Click here to switch to the map view.

The map label for this gene is yhcK [H]

Identifier: 238921986

GI number: 238921986

Start: 180170

End: 181735

Strand: Reverse

Name: yhcK [H]

Synonym: EUBELI_20221

Alternate gene names: 238921986

Gene position: 181735-180170 (Counterclockwise)

Preceding gene: 238921987

Following gene: 238921985

Centisome position: 29.0

GC content: 36.97

Gene sequence:

>1566_bases
ATGCATTTTATAAAGAAAAATATTATTATTCCACTTGTTGTATTTATAATCGGAATGAGTGCTGTGGCAGGTATTGTATG
CAGCATAAATAACGAGCAGAATAAGCAGAACAGGACAATGGCGAATCTTAACGCAATGACTTATGCAGAGCGTATGAAGA
CGGATATTATGAAAGGCATAGCCGTTTCGGACTCATTAAGACAGATAATTATAAGTGAAGATGGACAGCTTAATAAATTC
TGTGAGATAGCAGAGGAGATGATGGCAGATTCTGTTCAGAGTATCCAGATTGCACCAGATGGTGTTGTGACAGATATTTA
TCCTCAGGAAGGCAATGATGCGGGAAAGATTGATTTGTTAAATGACAAAGATCGTGGTGAAATATGCCGTTATGGAAGAG
ATAATAAAGTTGTTACAATGCAGGGACCATTTCAATTAAAGCAAGGGGGATATGGTATAGTTGTAAGAAATCCTGTATAT
ATTGAAGAAAACGGACATGAAGATTTCTGGGGATTTGCAATAGTTATAATCCGTGTTCCTGAGATTTTTGCTGATTCAAT
GAAGGCACTTTCTGATTTTGGTTATAATTATATATTATATAAAACTGCTTTTCCGTGGGGGTCTGAATTTGAAGAAGTGT
ATGGCTCGGAAGAAGAGTTAAAGAATCCTGTTTCATATACATTTGATATAGGAGACAGCAAGTGGAAGCTTGATATAATG
CCATATAAGACTCAGTCTGAAAGAAGATATCTGTATGCGGCTGGAATAGGCGGAGTTATTATTGTTCTGCTTCTTACAGG
ATTTACATGTGCTCTGCTTGTGCTTGACAAACACAGAAAGAAGTTTAAGAAACTGGCTATAACAGATGCTTTGACAGGAA
TATATAACCGTCATGGATATGATGAAAGAGTAACAAGGTATCTTAAGCAGAATCCGGATAATCACTGTGTAGGAGTAGAA
TTTGATATTGATGATTTTAAGACTATCAATGATATGTATGGCCATGTTTATGGCGATGTGGCACTTAAGGTATTGTCCGA
GGGAATGCAGAAGTTTTTTGATAAAAATGTGGTTTTAGGACGAAATGGTGGTGATGAATTCTGTATTTTCCTGCCAGACT
GCACATGTGCAGATGTTAAGGAAAAACTTGAGGAATTCACAAAGTTAAAACGTTCATTTAAATATGAAGGTGAAGAGCAG
CAGTTCACTATATCAGTTGGATATGCTGAATATCCGGTTCATGCTGACAAGCCATCAAAGCTCATGCGTTGTGCTGATAC
TGCACTTTATGAGGTGAAACTTCGTGGAAAAAATGGCTGCATGGCATATAAGAACGGACTCAGGATGGAGATTCGTACAC
AGCTTGGTTTTGCACTTAAAGATGTTTCTGAAAATCTTCCAGGAGCATTTATCATATACAAAGCAGATAAGAATGATGAT
GAAATTCTTTTTGCAAACCGTGAATTTATCAGATTTGCAGGCTGTAAGAACATGGATGAACTGCTTGAATATACAAAAAG
AAGTTTCCGTAATATCTTAGAGTGGATGAACGGGAAGCTGTTATAG

Upstream 100 bases:

>100_bases
CAGTGACGCAGGAAATTCCTGCGTCATTTTTAATGCGGAATAAAATTTAAAGTGATATAATAAATAAATATTTACAAATC
AGCAGTTTGGAGTGAATGAA

Downstream 100 bases:

>100_bases
CGGATATATGGAAGCAGATAGATGAAGGACATACTAATGGTTATACGCATTTTAATATGCAGAAAGCAGATGGCGGGCAT
ATACAGGTGTTTGACCATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MHFIKKNIIIPLVVFIIGMSAVAGIVCSINNEQNKQNRTMANLNAMTYAERMKTDIMKGIAVSDSLRQIIISEDGQLNKF
CEIAEEMMADSVQSIQIAPDGVVTDIYPQEGNDAGKIDLLNDKDRGEICRYGRDNKVVTMQGPFQLKQGGYGIVVRNPVY
IEENGHEDFWGFAIVIIRVPEIFADSMKALSDFGYNYILYKTAFPWGSEFEEVYGSEEELKNPVSYTFDIGDSKWKLDIM
PYKTQSERRYLYAAGIGGVIIVLLLTGFTCALLVLDKHRKKFKKLAITDALTGIYNRHGYDERVTRYLKQNPDNHCVGVE
FDIDDFKTINDMYGHVYGDVALKVLSEGMQKFFDKNVVLGRNGGDEFCIFLPDCTCADVKEKLEEFTKLKRSFKYEGEEQ
QFTISVGYAEYPVHADKPSKLMRCADTALYEVKLRGKNGCMAYKNGLRMEIRTQLGFALKDVSENLPGAFIIYKADKNDD
EILFANREFIRFAGCKNMDELLEYTKRSFRNILEWMNGKLL

Sequences:

>Translated_521_residues
MHFIKKNIIIPLVVFIIGMSAVAGIVCSINNEQNKQNRTMANLNAMTYAERMKTDIMKGIAVSDSLRQIIISEDGQLNKF
CEIAEEMMADSVQSIQIAPDGVVTDIYPQEGNDAGKIDLLNDKDRGEICRYGRDNKVVTMQGPFQLKQGGYGIVVRNPVY
IEENGHEDFWGFAIVIIRVPEIFADSMKALSDFGYNYILYKTAFPWGSEFEEVYGSEEELKNPVSYTFDIGDSKWKLDIM
PYKTQSERRYLYAAGIGGVIIVLLLTGFTCALLVLDKHRKKFKKLAITDALTGIYNRHGYDERVTRYLKQNPDNHCVGVE
FDIDDFKTINDMYGHVYGDVALKVLSEGMQKFFDKNVVLGRNGGDEFCIFLPDCTCADVKEKLEEFTKLKRSFKYEGEEQ
QFTISVGYAEYPVHADKPSKLMRCADTALYEVKLRGKNGCMAYKNGLRMEIRTQLGFALKDVSENLPGAFIIYKADKNDD
EILFANREFIRFAGCKNMDELLEYTKRSFRNILEWMNGKLL
>Mature_521_residues
MHFIKKNIIIPLVVFIIGMSAVAGIVCSINNEQNKQNRTMANLNAMTYAERMKTDIMKGIAVSDSLRQIIISEDGQLNKF
CEIAEEMMADSVQSIQIAPDGVVTDIYPQEGNDAGKIDLLNDKDRGEICRYGRDNKVVTMQGPFQLKQGGYGIVVRNPVY
IEENGHEDFWGFAIVIIRVPEIFADSMKALSDFGYNYILYKTAFPWGSEFEEVYGSEEELKNPVSYTFDIGDSKWKLDIM
PYKTQSERRYLYAAGIGGVIIVLLLTGFTCALLVLDKHRKKFKKLAITDALTGIYNRHGYDERVTRYLKQNPDNHCVGVE
FDIDDFKTINDMYGHVYGDVALKVLSEGMQKFFDKNVVLGRNGGDEFCIFLPDCTCADVKEKLEEFTKLKRSFKYEGEEQ
QFTISVGYAEYPVHADKPSKLMRCADTALYEVKLRGKNGCMAYKNGLRMEIRTQLGFALKDVSENLPGAFIIYKADKNDD
EILFANREFIRFAGCKNMDELLEYTKRSFRNILEWMNGKLL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=163, Percent_Identity=31.9018404907975, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787802, Length=200, Percent_Identity=32, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=27.810650887574, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=32.2981366459627, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788381, Length=173, Percent_Identity=28.9017341040462, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=184, Percent_Identity=29.8913043478261, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693134, Length=133, Percent_Identity=34.5864661654135, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082007, Length=209, Percent_Identity=26.7942583732057, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081977, Length=155, Percent_Identity=30.9677419354839, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787816, Length=154, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 59405; Mature: 59405

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50839 CHASE ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFIKKNIIIPLVVFIIGMSAVAGIVCSINNEQNKQNRTMANLNAMTYAERMKTDIMKGI
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSDSLRQIIISEDGQLNKFCEIAEEMMADSVQSIQIAPDGVVTDIYPQEGNDAGKIDLL
HHHHHHHHEEECCCCCHHHHHHHHHHHHHCCHHEEEECCCCCEEECCCCCCCCCCEEEEE
NDKDRGEICRYGRDNKVVTMQGPFQLKQGGYGIVVRNPVYIEENGHEDFWGFAIVIIRVP
CCCCCCHHHHCCCCCEEEEEECCEEECCCCEEEEECCEEEEECCCCCCHHHEEEEEEECC
EIFADSMKALSDFGYNYILYKTAFPWGSEFEEVYGSEEELKNPVSYTFDIGDSKWKLDIM
HHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCCCHHHHCCCCEEEEECCCCEEEEEEE
PYKTQSERRYLYAAGIGGVIIVLLLTGFTCALLVLDKHRKKFKKLAITDALTGIYNRHGY
CCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DERVTRYLKQNPDNHCVGVEFDIDDFKTINDMYGHVYGDVALKVLSEGMQKFFDKNVVLG
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
RNGGDEFCIFLPDCTCADVKEKLEEFTKLKRSFKYEGEEQQFTISVGYAEYPVHADKPSK
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCCCCCCHHH
LMRCADTALYEVKLRGKNGCMAYKNGLRMEIRTQLGFALKDVSENLPGAFIIYKADKNDD
HHHHHHCEEEEEEEECCCCCEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCC
EILFANREFIRFAGCKNMDELLEYTKRSFRNILEWMNGKLL
CEEEECCHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHFIKKNIIIPLVVFIIGMSAVAGIVCSINNEQNKQNRTMANLNAMTYAERMKTDIMKGI
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSDSLRQIIISEDGQLNKFCEIAEEMMADSVQSIQIAPDGVVTDIYPQEGNDAGKIDLL
HHHHHHHHEEECCCCCHHHHHHHHHHHHHCCHHEEEECCCCCEEECCCCCCCCCCEEEEE
NDKDRGEICRYGRDNKVVTMQGPFQLKQGGYGIVVRNPVYIEENGHEDFWGFAIVIIRVP
CCCCCCHHHHCCCCCEEEEEECCEEECCCCEEEEECCEEEEECCCCCCHHHEEEEEEECC
EIFADSMKALSDFGYNYILYKTAFPWGSEFEEVYGSEEELKNPVSYTFDIGDSKWKLDIM
HHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHCCCHHHHCCCCEEEEECCCCEEEEEEE
PYKTQSERRYLYAAGIGGVIIVLLLTGFTCALLVLDKHRKKFKKLAITDALTGIYNRHGY
CCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DERVTRYLKQNPDNHCVGVEFDIDDFKTINDMYGHVYGDVALKVLSEGMQKFFDKNVVLG
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
RNGGDEFCIFLPDCTCADVKEKLEEFTKLKRSFKYEGEEQQFTISVGYAEYPVHADKPSK
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCCCCCCHHH
LMRCADTALYEVKLRGKNGCMAYKNGLRMEIRTQLGFALKDVSENLPGAFIIYKADKNDD
HHHHHHCEEEEEEEECCCCCEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCC
EILFANREFIRFAGCKNMDELLEYTKRSFRNILEWMNGKLL
CEEEECCHHHEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]