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The map label for this gene is lipA [H]

Identifier: 238921977

GI number: 238921977

Start: 172932

End: 174125

Strand: Reverse

Name: lipA [H]

Synonym: EUBELI_20212

Alternate gene names: 238921977

Gene position: 174125-172932 (Counterclockwise)

Preceding gene: 238921978

Following gene: 238921976

Centisome position: 27.78

GC content: 41.46

Gene sequence:

>1194_bases
ATGGGGAGAATTAAAGTATGTAACTTTGGCAGAATTATGCTGAAAATATTCTGCTGGACGACAGTAATATTAGCAATATA
TCTTATATTAGGTATTACAGGCTGTTATGAAAAATGGTTTGGCGGTCCGGCAGGAATAGTAAAAACGCCAGTTTACTGGC
TTATCCGGGCAGGGATAGGAATTCTTGTGGAAAGCATTATTTTCTGGATAGGAATTATTATGGTGTATGCGACATCTGAG
CAGCTTGGGATCAGATGGAGAGTGCTTGGAATCGTGTGTGGATGGATACCTGTTGCACATCTTGTCATGCTTCATATTAT
TATAAAGACAGTTGGTGAGGAAGTCCGCATGGAGGAAATGCGTGCTAAGAGAAATCTGCAGCGCAAAGAACAGCGGATAT
GCAGTACTAAATATCCTGTTCTTATGGTGCATGGCGTATTTTTCAGGGATTTTGAACATCTTAATTACTGGGGAAGAATA
CCGGCAGAGCTTGAGGCTAATGGTGCAGTGATTTGTTATGGCAATCATAACAGTGCGGCGGCCGTGCGAGACAGTGCTAA
AGAGCTGGCAGAAAGGATTCACCAGATTGTCATTAAGACAGGCTGTGAGAAAGTAAATGTAATTGCCCATTCAAAAGGCG
GACTGGACATGAGGGCAGCGATAGCACTTACAGATATTGCACCTTATGTGGCTTCTCTTACAACGATAAATACACCACAC
AGGGGCTGTCAGTTTGCTGATTATCTTCTTGGCAAAATTCCTGAAAAACAGCAGCAGATGGTTGCAAATGCATATAACGC
TGGAGCGGCTAAACTCGGAGACATTAACCCTGATTTTCTTGCTGCCGTATATGACCTTACATCAGAAAAATGCAGTGAAT
TCAACAATGAAATAAAGGATAATCCAGACATTTATTATCAGTCAGTTGGTTCTAAACTAAACCATCCGGCTTCGGGAAGA
TTTCCACTTAATTTTACATATCCACTGGTGAAATATTTTGACGGACCTAATGACGGACTTGTTGGAGAAGAATCCTTTCG
ATGGGGACAGAACTATCAGTTTCTTACTGTCAGCGGTAAAAGAGGTATATCGCATGGTGATATGATAGATCTTAACAGGG
AGAACATTAAAGGATTTGATGTTCGGGAATTTTATGTGCAGGTTGTTGCGGGACTTAAGAAGATGGGGTTTTGA

Upstream 100 bases:

>100_bases
GATAATATTCCGAAGAGAAATATATGTCTTGTCTATGACAGCAGACACCCGGTGAGTTCGGCGGCAAGAAAGTTGAGAAA
AACAATAGGGGAGATTAATT

Downstream 100 bases:

>100_bases
TTTTTAAAATACAAATTATAAATTTTTAGTAAAATAAAATATTTGTAATTGACATATTTCTTGAAGATAGGTAATATAAT
ATTAAAGATAGGTAACTTGA

Product: triacylglycerol lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MGRIKVCNFGRIMLKIFCWTTVILAIYLILGITGCYEKWFGGPAGIVKTPVYWLIRAGIGILVESIIFWIGIIMVYATSE
QLGIRWRVLGIVCGWIPVAHLVMLHIIIKTVGEEVRMEEMRAKRNLQRKEQRICSTKYPVLMVHGVFFRDFEHLNYWGRI
PAELEANGAVICYGNHNSAAAVRDSAKELAERIHQIVIKTGCEKVNVIAHSKGGLDMRAAIALTDIAPYVASLTTINTPH
RGCQFADYLLGKIPEKQQQMVANAYNAGAAKLGDINPDFLAAVYDLTSEKCSEFNNEIKDNPDIYYQSVGSKLNHPASGR
FPLNFTYPLVKYFDGPNDGLVGEESFRWGQNYQFLTVSGKRGISHGDMIDLNRENIKGFDVREFYVQVVAGLKKMGF

Sequences:

>Translated_397_residues
MGRIKVCNFGRIMLKIFCWTTVILAIYLILGITGCYEKWFGGPAGIVKTPVYWLIRAGIGILVESIIFWIGIIMVYATSE
QLGIRWRVLGIVCGWIPVAHLVMLHIIIKTVGEEVRMEEMRAKRNLQRKEQRICSTKYPVLMVHGVFFRDFEHLNYWGRI
PAELEANGAVICYGNHNSAAAVRDSAKELAERIHQIVIKTGCEKVNVIAHSKGGLDMRAAIALTDIAPYVASLTTINTPH
RGCQFADYLLGKIPEKQQQMVANAYNAGAAKLGDINPDFLAAVYDLTSEKCSEFNNEIKDNPDIYYQSVGSKLNHPASGR
FPLNFTYPLVKYFDGPNDGLVGEESFRWGQNYQFLTVSGKRGISHGDMIDLNRENIKGFDVREFYVQVVAGLKKMGF
>Mature_396_residues
GRIKVCNFGRIMLKIFCWTTVILAIYLILGITGCYEKWFGGPAGIVKTPVYWLIRAGIGILVESIIFWIGIIMVYATSEQ
LGIRWRVLGIVCGWIPVAHLVMLHIIIKTVGEEVRMEEMRAKRNLQRKEQRICSTKYPVLMVHGVFFRDFEHLNYWGRIP
AELEANGAVICYGNHNSAAAVRDSAKELAERIHQIVIKTGCEKVNVIAHSKGGLDMRAAIALTDIAPYVASLTTINTPHR
GCQFADYLLGKIPEKQQQMVANAYNAGAAKLGDINPDFLAAVYDLTSEKCSEFNNEIKDNPDIYYQSVGSKLNHPASGRF
PLNFTYPLVKYFDGPNDGLVGEESFRWGQNYQFLTVSGKRGISHGDMIDLNRENIKGFDVREFYVQVVAGLKKMGF

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=267, Percent_Identity=26.5917602996255, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 44596; Mature: 44464

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRIKVCNFGRIMLKIFCWTTVILAIYLILGITGCYEKWFGGPAGIVKTPVYWLIRAGIG
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILVESIIFWIGIIMVYATSEQLGIRWRVLGIVCGWIPVAHLVMLHIIIKTVGEEVRMEEM
HHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKRNLQRKEQRICSTKYPVLMVHGVFFRDFEHLNYWGRIPAELEANGAVICYGNHNSAA
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCCCCH
AVRDSAKELAERIHQIVIKTGCEKVNVIAHSKGGLDMRAAIALTDIAPYVASLTTINTPH
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
RGCQFADYLLGKIPEKQQQMVANAYNAGAAKLGDINPDFLAAVYDLTSEKCSEFNNEIKD
CCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NPDIYYQSVGSKLNHPASGRFPLNFTYPLVKYFDGPNDGLVGEESFRWGQNYQFLTVSGK
CCCHHHHHHHHHCCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECC
RGISHGDMIDLNRENIKGFDVREFYVQVVAGLKKMGF
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRIKVCNFGRIMLKIFCWTTVILAIYLILGITGCYEKWFGGPAGIVKTPVYWLIRAGIG
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ILVESIIFWIGIIMVYATSEQLGIRWRVLGIVCGWIPVAHLVMLHIIIKTVGEEVRMEEM
HHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKRNLQRKEQRICSTKYPVLMVHGVFFRDFEHLNYWGRIPAELEANGAVICYGNHNSAA
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCCCCH
AVRDSAKELAERIHQIVIKTGCEKVNVIAHSKGGLDMRAAIALTDIAPYVASLTTINTPH
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
RGCQFADYLLGKIPEKQQQMVANAYNAGAAKLGDINPDFLAAVYDLTSEKCSEFNNEIKD
CCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NPDIYYQSVGSKLNHPASGRFPLNFTYPLVKYFDGPNDGLVGEESFRWGQNYQFLTVSGK
CCCHHHHHHHHHCCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECC
RGISHGDMIDLNRENIKGFDVREFYVQVVAGLKKMGF
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1476423; 7786905; 8405390; 8683577 [H]