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The map label for this gene is nagA [H]

Identifier: 238921847

GI number: 238921847

Start: 61715

End: 62848

Strand: Reverse

Name: nagA [H]

Synonym: EUBELI_20080

Alternate gene names: 238921847

Gene position: 62848-61715 (Counterclockwise)

Preceding gene: 238921848

Following gene: 238921846

Centisome position: 10.03

GC content: 38.98

Gene sequence:

>1134_bases
ATGATTATAAAGAATGCTGATGTTTATACACAGGACAATGTATTTGTTAAGGGAGATGTCGTTGTAGATAACGGTACATT
CACCAAAGTGCTGGATGTACATAATTATGTTGGCGATGAAGTTGTAGATGCTACAGGACTTAAGATGATTCCAGGACTTG
TTGACATTCATTTTCATGGATGCAAAGGCGCAGATATGTGTGATGGAACTAAAGAGGCACTTGATATAATTTCGCGGTAT
GAGGCTTCTGTCGGAGTGACGAGTATATGTCCGGCAACCATGACGATAGCTAAGGAAGAACTTGTTGAAGTTATGAAGAA
TGCCGGAGAGTATTTATATAATGGTGGAGCCCATCTGGTAGGAATTAATATGGAGGGACCTTTTATAAGTCCACAAAAAA
AGGGTGCACAGGCAGCAGAGAATATTATGCATTGTAATTATGAGTATTTCTGTGAACTCCAGAAAGCTGCACATGATTTA
ATAAAGATTGTTGATATTGCACCAGAAGAGCCGGGTGCGATGAATTTCATAGATAAAGTAAAAGATAATGTTGTGGTGTC
GATTGCTCATACAGCAGCAGATTATGATACTGCGATGGAGGCAATTCAACATGGTGCAACTCATGCAACACATTTATACA
ATGCAATGCCCCCTATGAATCATAGAAAGCCTGGTGTTATAGGTGCAATAAGAGATTCATATCAATGTCATGCAGAACTG
ATATGTGATGGAGTTCATATTCATCCATCAGTAATACGGGCAACATTTGCTATGTTGGGTGCGGGACGCATAATACTAAT
CAGTGACAGCATGAGAGCAACAGGATTAGAGGATGGCGAATATACTCTTGGAGGACAGCCTGTAGTGGTAAAAGGTAATC
TGGCAACATTACATGATGGAACAATTGCCGGTTCAGCAACTAATTTAATGGATTGTCTTCGATATGTCGTTAAAAAAGCA
GGGATTTCATTAGAAACAGCTGTTATGTGTGCAACAGAGAATCCGGCAAAGGAAATTGGTATATATGATAAAGTCGGAAG
TATTTCTGTAGGAAAACAAGCGGATTTCGTGCTTATTGATGAGGAATTGAATATTAAGAGGGTATATATTGATGGAAAGG
AGATAATATGCTAG

Upstream 100 bases:

>100_bases
TTTGCAGCTGCATAATGATGTAACACTGGTAGCAGATGAAGCAGCTCTTAGTAAGATTTACTAAAGCTTATTAACTTGGT
GGATAGAAGGTTGAGAACAT

Downstream 100 bases:

>100_bases
GTTTTTTCAAAGGAAAGTCAAAGGATAATGTTATTTATTCTCCGTGTAAAGGAAAAGTGGTGCCAATTACTGAAGTTTCA
GATCCAACATTTTCAGAAAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MIIKNADVYTQDNVFVKGDVVVDNGTFTKVLDVHNYVGDEVVDATGLKMIPGLVDIHFHGCKGADMCDGTKEALDIISRY
EASVGVTSICPATMTIAKEELVEVMKNAGEYLYNGGAHLVGINMEGPFISPQKKGAQAAENIMHCNYEYFCELQKAAHDL
IKIVDIAPEEPGAMNFIDKVKDNVVVSIAHTAADYDTAMEAIQHGATHATHLYNAMPPMNHRKPGVIGAIRDSYQCHAEL
ICDGVHIHPSVIRATFAMLGAGRIILISDSMRATGLEDGEYTLGGQPVVVKGNLATLHDGTIAGSATNLMDCLRYVVKKA
GISLETAVMCATENPAKEIGIYDKVGSISVGKQADFVLIDEELNIKRVYIDGKEIIC

Sequences:

>Translated_377_residues
MIIKNADVYTQDNVFVKGDVVVDNGTFTKVLDVHNYVGDEVVDATGLKMIPGLVDIHFHGCKGADMCDGTKEALDIISRY
EASVGVTSICPATMTIAKEELVEVMKNAGEYLYNGGAHLVGINMEGPFISPQKKGAQAAENIMHCNYEYFCELQKAAHDL
IKIVDIAPEEPGAMNFIDKVKDNVVVSIAHTAADYDTAMEAIQHGATHATHLYNAMPPMNHRKPGVIGAIRDSYQCHAEL
ICDGVHIHPSVIRATFAMLGAGRIILISDSMRATGLEDGEYTLGGQPVVVKGNLATLHDGTIAGSATNLMDCLRYVVKKA
GISLETAVMCATENPAKEIGIYDKVGSISVGKQADFVLIDEELNIKRVYIDGKEIIC
>Mature_377_residues
MIIKNADVYTQDNVFVKGDVVVDNGTFTKVLDVHNYVGDEVVDATGLKMIPGLVDIHFHGCKGADMCDGTKEALDIISRY
EASVGVTSICPATMTIAKEELVEVMKNAGEYLYNGGAHLVGINMEGPFISPQKKGAQAAENIMHCNYEYFCELQKAAHDL
IKIVDIAPEEPGAMNFIDKVKDNVVVSIAHTAADYDTAMEAIQHGATHATHLYNAMPPMNHRKPGVIGAIRDSYQCHAEL
ICDGVHIHPSVIRATFAMLGAGRIILISDSMRATGLEDGEYTLGGQPVVVKGNLATLHDGTIAGSATNLMDCLRYVVKKA
GISLETAVMCATENPAKEIGIYDKVGSISVGKQADFVLIDEELNIKRVYIDGKEIIC

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=419, Percent_Identity=29.1169451073986, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI224922791, Length=419, Percent_Identity=29.1169451073986, Blast_Score=172, Evalue=6e-43,
Organism=Escherichia coli, GI1786892, Length=338, Percent_Identity=27.5147928994083, Blast_Score=155, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=386, Percent_Identity=31.3471502590674, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI19920392, Length=347, Percent_Identity=31.9884726224784, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI281361140, Length=356, Percent_Identity=31.7415730337079, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40656; Mature: 40656

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKNADVYTQDNVFVKGDVVVDNGTFTKVLDVHNYVGDEVVDATGLKMIPGLVDIHFHG
CEEECCCCEECCCEEEEEEEEEECCCEEEHHHHHHHCCCHHCCCCCCCCCCCEEEEEEEC
CKGADMCDGTKEALDIISRYEASVGVTSICPATMTIAKEELVEVMKNAGEYLYNGGAHLV
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHCCCCEEECCCCEEE
GINMEGPFISPQKKGAQAAENIMHCNYEYFCELQKAAHDLIKIVDIAPEEPGAMNFIDKV
EEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
KDNVVVSIAHTAADYDTAMEAIQHGATHATHLYNAMPPMNHRKPGVIGAIRDSYQCHAEL
CCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEECCCHHEEEHH
ICDGVHIHPSVIRATFAMLGAGRIILISDSMRATGLEDGEYTLGGQPVVVKGNLATLHDG
EECCCEECHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCEEEEEECCEEEEECC
TIAGSATNLMDCLRYVVKKAGISLETAVMCATENPAKEIGIYDKVGSISVGKQADFVLID
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHCCCEECCCCEECCCCCCEEEEE
EELNIKRVYIDGKEIIC
CCCCEEEEEECCCEECC
>Mature Secondary Structure
MIIKNADVYTQDNVFVKGDVVVDNGTFTKVLDVHNYVGDEVVDATGLKMIPGLVDIHFHG
CEEECCCCEECCCEEEEEEEEEECCCEEEHHHHHHHCCCHHCCCCCCCCCCCEEEEEEEC
CKGADMCDGTKEALDIISRYEASVGVTSICPATMTIAKEELVEVMKNAGEYLYNGGAHLV
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHCCCCEEECCCCEEE
GINMEGPFISPQKKGAQAAENIMHCNYEYFCELQKAAHDLIKIVDIAPEEPGAMNFIDKV
EEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHH
KDNVVVSIAHTAADYDTAMEAIQHGATHATHLYNAMPPMNHRKPGVIGAIRDSYQCHAEL
CCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEECCCHHEEEHH
ICDGVHIHPSVIRATFAMLGAGRIILISDSMRATGLEDGEYTLGGQPVVVKGNLATLHDG
EECCCEECHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCEEEEEECCEEEEECC
TIAGSATNLMDCLRYVVKKAGISLETAVMCATENPAKEIGIYDKVGSISVGKQADFVLID
CCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHCCCEECCCCEECCCCCCEEEEE
EELNIKRVYIDGKEIIC
CCCCEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]