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The map label for this gene is purP [H]

Identifier: 238921757

GI number: 238921757

Start: 3803666

End: 3804910

Strand: Direct

Name: purP [H]

Synonym: NT01EI_3926

Alternate gene names: 238921757

Gene position: 3803666-3804910 (Clockwise)

Preceding gene: 238921756

Following gene: 238921759

Centisome position: 99.77

GC content: 59.12

Gene sequence:

>1245_bases
GTGATTGCCGGTTTCACCACGTTCCTCACCATGGTGTATATCGTCTTCGTTAACCCGCAGATCCTCAGTGCCGCAGGCAT
GGATACCCAGGCCGTGTTTGTGACGACCTGTCTGATTGCTGCCTTCGGCAGTATTCTTATGGGGGTGTTAGCCAATCTTC
CGGTCGCGCTGGCGCCGGCGATGGGGCTGAATGCCTTCTTTGCTTTCGTGGTCGTCGGGGCAATGGGGCTCTCCTGGCAG
ATCGGGATGGGCGCCATTTTCTGGGGCGCCGTCGCTCTGCTGCTGCTGACGATATTCCGTATTCGCTATTGGATGATCGC
CAATATTCCGCTGAGTCTGCGGGTGGGGATCACCAGCGGTATCGGCCTGTTTATTGCCATGATGGGGCTCAAAAACGCCG
GCATCATCGTGCCGAACCAGGATACGCTGGTGACCGTGGGGGAGCTGACGTCGCACCATGTCCTGCTGGGAGCGCTGGGC
TTTTTCATCATCGCTGTTCTGGCATCGCGCAACATTCACGCCGCGGTGCTGGTATCTATTGTGGTGACCACGGCTATCGG
TCTGCTGTTGGGTGACGTGCAGTACAGCGGCATTTTCTCCATGCCGCCCAGCGTGACCAGCGTAGTCGGTCAGGTCGATT
TGAGCGGCGCGCTGAATATCGGTCTGTCCGGTGTTATCTTCTCCTTTATGCTGGTGAACCTGTTTGACTCCTCGGGCACG
CTGATTGGCGTTACGGATAAAGCAGGTCTGACGGACGTCAACGGCAAGTTTCCGCGCATGCAGCAGGCGCTGTATGTGGA
CAGTATCAGCTCCGTCGCCGGTTCTTTTATCGGTACCTCCTCTGTGACCGCCTATATTGAAAGCTCCTCTGGGGTCTCCG
TCGGCGGGCGCACTGGCCTGACCGCCGTGGTGGTGGGGCTGCTGTTTATGCTGGTTATCTTTCTCTCTCCGCTGGCGGCC
ATGGTGCCGGGATATGCTGCCGCTGGGGCGCTGATCTACGTCGGCGTGCTGATGACCTCGAGTCTGGCGCGGGTTACGTG
GGACGATCTGACCGAGGCGGTACCGGCGTTTATTACCGCGGTGATGATGCCGTTCAGCTTCTCGATCACCGAGGGGATCG
CGCTCGGCTTTATCGCCTACTGCGTGATGAAGGCGGGCACGGGACGCTGGCGTGAGATTAGCCCCTGCGTGGTGGTGGTG
GCGCTGCTGTTTGTGCTGAAGATAGCGTTGGTTGACGCGCACTGA

Upstream 100 bases:

>100_bases
TTCATGTATGAGCCAATCCACGTCCAATACCGCTCACTCCCGGGGCGTATTCGAGCGCGTCTTTAAACTACAGGCACATG
GTACCACCGTCAGGACCGAA

Downstream 100 bases:

>100_bases
TCCATGCAATGGGACGCAGCGACAGGGAGGGCATTGGCCCTCCCTGTTTGTTTATGGAGTATGGCAGTCGTCCATAAGTC
AGCGCAGCGGCTGGCGATAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MIAGFTTFLTMVYIVFVNPQILSAAGMDTQAVFVTTCLIAAFGSILMGVLANLPVALAPAMGLNAFFAFVVVGAMGLSWQ
IGMGAIFWGAVALLLLTIFRIRYWMIANIPLSLRVGITSGIGLFIAMMGLKNAGIIVPNQDTLVTVGELTSHHVLLGALG
FFIIAVLASRNIHAAVLVSIVVTTAIGLLLGDVQYSGIFSMPPSVTSVVGQVDLSGALNIGLSGVIFSFMLVNLFDSSGT
LIGVTDKAGLTDVNGKFPRMQQALYVDSISSVAGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGLLFMLVIFLSPLAA
MVPGYAAAGALIYVGVLMTSSLARVTWDDLTEAVPAFITAVMMPFSFSITEGIALGFIAYCVMKAGTGRWREISPCVVVV
ALLFVLKIALVDAH

Sequences:

>Translated_414_residues
MIAGFTTFLTMVYIVFVNPQILSAAGMDTQAVFVTTCLIAAFGSILMGVLANLPVALAPAMGLNAFFAFVVVGAMGLSWQ
IGMGAIFWGAVALLLLTIFRIRYWMIANIPLSLRVGITSGIGLFIAMMGLKNAGIIVPNQDTLVTVGELTSHHVLLGALG
FFIIAVLASRNIHAAVLVSIVVTTAIGLLLGDVQYSGIFSMPPSVTSVVGQVDLSGALNIGLSGVIFSFMLVNLFDSSGT
LIGVTDKAGLTDVNGKFPRMQQALYVDSISSVAGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGLLFMLVIFLSPLAA
MVPGYAAAGALIYVGVLMTSSLARVTWDDLTEAVPAFITAVMMPFSFSITEGIALGFIAYCVMKAGTGRWREISPCVVVV
ALLFVLKIALVDAH
>Mature_414_residues
MIAGFTTFLTMVYIVFVNPQILSAAGMDTQAVFVTTCLIAAFGSILMGVLANLPVALAPAMGLNAFFAFVVVGAMGLSWQ
IGMGAIFWGAVALLLLTIFRIRYWMIANIPLSLRVGITSGIGLFIAMMGLKNAGIIVPNQDTLVTVGELTSHHVLLGALG
FFIIAVLASRNIHAAVLVSIVVTTAIGLLLGDVQYSGIFSMPPSVTSVVGQVDLSGALNIGLSGVIFSFMLVNLFDSSGT
LIGVTDKAGLTDVNGKFPRMQQALYVDSISSVAGSFIGTSSVTAYIESSSGVSVGGRTGLTAVVVGLLFMLVIFLSPLAA
MVPGYAAAGALIYVGVLMTSSLARVTWDDLTEAVPAFITAVMMPFSFSITEGIALGFIAYCVMKAGTGRWREISPCVVVV
ALLFVLKIALVDAH

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=413, Percent_Identity=85.2300242130751, Blast_Score=680, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=412, Percent_Identity=77.6699029126214, Blast_Score=645, Evalue=0.0,
Organism=Escherichia coli, GI1790499, Length=412, Percent_Identity=37.378640776699, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI48994909, Length=407, Percent_Identity=36.3636363636364, Blast_Score=234, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 43103; Mature: 43103

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAGFTTFLTMVYIVFVNPQILSAAGMDTQAVFVTTCLIAAFGSILMGVLANLPVALAPA
CCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MGLNAFFAFVVVGAMGLSWQIGMGAIFWGAVALLLLTIFRIRYWMIANIPLSLRVGITSG
HHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCH
IGLFIAMMGLKNAGIIVPNQDTLVTVGELTSHHVLLGALGFFIIAVLASRNIHAAVLVSI
HHHHHHHHCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VVTTAIGLLLGDVQYSGIFSMPPSVTSVVGQVDLSGALNIGLSGVIFSFMLVNLFDSSGT
HHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCC
LIGVTDKAGLTDVNGKFPRMQQALYVDSISSVAGSFIGTSSVTAYIESSSGVSVGGRTGL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH
TAVVVGLLFMLVIFLSPLAAMVPGYAAAGALIYVGVLMTSSLARVTWDDLTEAVPAFITA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMMPFSFSITEGIALGFIAYCVMKAGTGRWREISPCVVVVALLFVLKIALVDAH
HHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAGFTTFLTMVYIVFVNPQILSAAGMDTQAVFVTTCLIAAFGSILMGVLANLPVALAPA
CCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MGLNAFFAFVVVGAMGLSWQIGMGAIFWGAVALLLLTIFRIRYWMIANIPLSLRVGITSG
HHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCH
IGLFIAMMGLKNAGIIVPNQDTLVTVGELTSHHVLLGALGFFIIAVLASRNIHAAVLVSI
HHHHHHHHCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VVTTAIGLLLGDVQYSGIFSMPPSVTSVVGQVDLSGALNIGLSGVIFSFMLVNLFDSSGT
HHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCC
LIGVTDKAGLTDVNGKFPRMQQALYVDSISSVAGSFIGTSSVTAYIESSSGVSVGGRTGL
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH
TAVVVGLLFMLVIFLSPLAAMVPGYAAAGALIYVGVLMTSSLARVTWDDLTEAVPAFITA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMMPFSFSITEGIALGFIAYCVMKAGTGRWREISPCVVVVALLFVLKIALVDAH
HHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]