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The map label for this gene is glnL [H]

Identifier: 238921703

GI number: 238921703

Start: 3743389

End: 3744456

Strand: Direct

Name: glnL [H]

Synonym: NT01EI_3864

Alternate gene names: 238921703

Gene position: 3743389-3744456 (Clockwise)

Preceding gene: 238921702

Following gene: 238921704

Centisome position: 98.19

GC content: 62.83

Gene sequence:

>1068_bases
ATGGCTGAATACCCTACGCCGCCCCACCGTGACCTACCCGATGCCGGGCCGCTGCTAAATGCCCTGATGACCTGCATCCT
GGTCCTGGACGACGATCTGGTCATTCGCTATGCCAATCCAGCCGCTCAGCAGCTGCTGGCGCAGAGCCCGCGTAAGCTGT
TTGGCACTCCGCTGCCGGATCTGCTGAGCTATCTTTCTTTGGATATCTCACTGATGCGCATCAGCCTGCGCACCGGACAG
GGTTTTACCGACAACGAGGTGATGCTGGTCATCGACAGCCAGCCGCACATCATGGCGCTGACGGCCCAGCCCCTGAGCGA
AGGGCAGATCCTGCTGGAGCTTTCCCCCCTGGACAGCCAGCGGCGCCTAAGCCAGGAGCAGCTCCAGCACTCCCAGCAGG
TCGCCGCCCGCGATCTGGTACGCGGGCTGGCCCATGAGATCAAAAACCCGCTCGGCGGGCTGCGCGGGGCAGCGCAGCTG
TTGGCCAGAGCACTACCGGATCCGGCCCTGACCGAGTACACCCAGGTGATCATTGAGCAGGCCGATCGCCTGCGCAACCT
GGTCGATCGTCTGCTGGGCCCCCAGAGGCCGGGGCAGCGCGTCACCCAGAGTATTCATCAAGTCGCCGAGCGGGTCTGCC
AGCTGGTCTCCCTGGAGTGCCCGGGGAACATCACCCTGCTGCGTGACTATGACCCCAGCCTGCCAGAGCTGAATCACGAT
CCGGAGCAAATCGAGCAGGTACTGCTGAACATCACGCGGAATGCCCTGCAGGCGCTGGGTGAGCGGGGCGGCACTATCAC
CCTGCGTACCCGTACAGCGCTGCAGGTCACCCTGCACGGCGAGCGCTATCGTCTGGCGGCGCGCATAGATATTGAAGACG
ATGGGCCAGGGGTCCCCGCCCAGCTGCAGGATACGCTGTTCTACCCAATGGTGAGCGGACGCAGCGGAGGCACCGGACTT
GGCCTGTCGATTGCAAGGAGCCTGATCGATCAGCATCAGGGAAAAATCGAGTTTAACAGCTGGCCGGGCCACACCGAGTT
TTCGGTATATTTGCCAATCCGCAAATAG

Upstream 100 bases:

>100_bases
GCAGGACGGAGAAAAAATTCTCCGCCCCCCCGCACAGGCAGCGAAAGCATGCTACAGTGCAAGGTATCCCATTGCACTAA
AATAGTGCAGGAGTGCACAA

Downstream 100 bases:

>100_bases
CCCACGCCCCTCACGCAACAGGTGGTCACCATGACAATGCAACCGGGTCTCGTCTGGATCGTCGACGATGACAGTGCCAT
CCGCTGGGTCTTAGAGCGCG

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MAEYPTPPHRDLPDAGPLLNALMTCILVLDDDLVIRYANPAAQQLLAQSPRKLFGTPLPDLLSYLSLDISLMRISLRTGQ
GFTDNEVMLVIDSQPHIMALTAQPLSEGQILLELSPLDSQRRLSQEQLQHSQQVAARDLVRGLAHEIKNPLGGLRGAAQL
LARALPDPALTEYTQVIIEQADRLRNLVDRLLGPQRPGQRVTQSIHQVAERVCQLVSLECPGNITLLRDYDPSLPELNHD
PEQIEQVLLNITRNALQALGERGGTITLRTRTALQVTLHGERYRLAARIDIEDDGPGVPAQLQDTLFYPMVSGRSGGTGL
GLSIARSLIDQHQGKIEFNSWPGHTEFSVYLPIRK

Sequences:

>Translated_355_residues
MAEYPTPPHRDLPDAGPLLNALMTCILVLDDDLVIRYANPAAQQLLAQSPRKLFGTPLPDLLSYLSLDISLMRISLRTGQ
GFTDNEVMLVIDSQPHIMALTAQPLSEGQILLELSPLDSQRRLSQEQLQHSQQVAARDLVRGLAHEIKNPLGGLRGAAQL
LARALPDPALTEYTQVIIEQADRLRNLVDRLLGPQRPGQRVTQSIHQVAERVCQLVSLECPGNITLLRDYDPSLPELNHD
PEQIEQVLLNITRNALQALGERGGTITLRTRTALQVTLHGERYRLAARIDIEDDGPGVPAQLQDTLFYPMVSGRSGGTGL
GLSIARSLIDQHQGKIEFNSWPGHTEFSVYLPIRK
>Mature_354_residues
AEYPTPPHRDLPDAGPLLNALMTCILVLDDDLVIRYANPAAQQLLAQSPRKLFGTPLPDLLSYLSLDISLMRISLRTGQG
FTDNEVMLVIDSQPHIMALTAQPLSEGQILLELSPLDSQRRLSQEQLQHSQQVAARDLVRGLAHEIKNPLGGLRGAAQLL
ARALPDPALTEYTQVIIEQADRLRNLVDRLLGPQRPGQRVTQSIHQVAERVCQLVSLECPGNITLLRDYDPSLPELNHDP
EQIEQVLLNITRNALQALGERGGTITLRTRTALQVTLHGERYRLAARIDIEDDGPGVPAQLQDTLFYPMVSGRSGGTGLG
LSIARSLIDQHQGKIEFNSWPGHTEFSVYLPIRK

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=343, Percent_Identity=79.0087463556851, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=31.5352697095436, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=31.3807531380753, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=31.6602316602317, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=243, Percent_Identity=27.5720164609054, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=24.6808510638298, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082128, Length=266, Percent_Identity=30.4511278195489, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=27.34375, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=24.0909090909091, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786600, Length=347, Percent_Identity=24.207492795389, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=27.2, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39263; Mature: 39131

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEYPTPPHRDLPDAGPLLNALMTCILVLDDDLVIRYANPAAQQLLAQSPRKLFGTPLPD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCHHHHCCCHHH
LLSYLSLDISLMRISLRTGQGFTDNEVMLVIDSQPHIMALTAQPLSEGQILLELSPLDSQ
HHHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEEECCCCHH
RRLSQEQLQHSQQVAARDLVRGLAHEIKNPLGGLRGAAQLLARALPDPALTEYTQVIIEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ADRLRNLVDRLLGPQRPGQRVTQSIHQVAERVCQLVSLECPGNITLLRDYDPSLPELNHD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCC
PEQIEQVLLNITRNALQALGERGGTITLRTRTALQVTLHGERYRLAARIDIEDDGPGVPA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCEEEEEEEEEECCCCCCCCH
QLQDTLFYPMVSGRSGGTGLGLSIARSLIDQHQGKIEFNSWPGHTEFSVYLPIRK
HHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure 
AEYPTPPHRDLPDAGPLLNALMTCILVLDDDLVIRYANPAAQQLLAQSPRKLFGTPLPD
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCHHHHCCCHHH
LLSYLSLDISLMRISLRTGQGFTDNEVMLVIDSQPHIMALTAQPLSEGQILLELSPLDSQ
HHHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEEECCCCHH
RRLSQEQLQHSQQVAARDLVRGLAHEIKNPLGGLRGAAQLLARALPDPALTEYTQVIIEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ADRLRNLVDRLLGPQRPGQRVTQSIHQVAERVCQLVSLECPGNITLLRDYDPSLPELNHD
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCC
PEQIEQVLLNITRNALQALGERGGTITLRTRTALQVTLHGERYRLAARIDIEDDGPGVPA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCEEEEEEEEEECCCCCCCCH
QLQDTLFYPMVSGRSGGTGLGLSIARSLIDQHQGKIEFNSWPGHTEFSVYLPIRK
HHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]