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The map label for this gene is dtd

Identifier: 238921697

GI number: 238921697

Start: 3737351

End: 3737788

Strand: Reverse

Name: dtd

Synonym: NT01EI_3858

Alternate gene names: 238921697

Gene position: 3737788-3737351 (Counterclockwise)

Preceding gene: 238921698

Following gene: 238921695

Centisome position: 98.05

GC content: 59.13

Gene sequence:

>438_bases
ATGATCGCATTAATTCAGCGGGTTACCCATGCCAGTGTGATGGTAGATAATCAGCTTATCGGAGAGATCGGCGCGGGCCT
GCTGGTGTTGCTGGGGGTGGAGAGAGGCGACGATGAGCAGAAGGCAAAGCGCTTGTGTGACAAGGTATTGGGCTACCGCG
TCTTTAGCGACGAAGAGGGTAAAATGAACCTCAACGTGCGCCAGTCCGGCGGCAGCGTGCTGGTGGTCTCTCAATTTACC
CTGGCGGCGGATACCCAAAAGGGGATGCGCCCCGGGTTTTCCCGCGGCGCTGCGCCGGATGAGGCTGAGCGCCTGTATAC
CCATTTTTCCGACGCCTGCCGCGCCAGCGGGATCACCACCGCGACCGGATGCTTTGCTGCCGATATGCAGGTCTCCCTGC
TCAATGACGGTCCGGTCACTTTCTGGCTGCAGGTTTAA

Upstream 100 bases:

>100_bases
GGTGACCGTGGCCATCGGCGATTTTCGGGCACACCGCCGGCAGGCGCAGGGGCTGCAGCAGGCGTTGACATCACATCATG
ATTAAGGAGTAAACGGTTCG

Downstream 100 bases:

>100_bases
GCCGATGGCGGCGTACAGCCTGTCATACGTCTGCGCCGCTGTCTCATCTACCCGCCATCCTCCCCACCAGCTGATCGCGC
AGCATCCGTGCGATCAGCGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRVTHASVMVDNQLIGEIGAGLLVLLGVERGDDEQKAKRLCDKVLGYRVFSDEEGKMNLNVRQSGGSVLVVSQFT
LAADTQKGMRPGFSRGAAPDEAERLYTHFSDACRASGITTATGCFAADMQVSLLNDGPVTFWLQV

Sequences:

>Translated_145_residues
MIALIQRVTHASVMVDNQLIGEIGAGLLVLLGVERGDDEQKAKRLCDKVLGYRVFSDEEGKMNLNVRQSGGSVLVVSQFT
LAADTQKGMRPGFSRGAAPDEAERLYTHFSDACRASGITTATGCFAADMQVSLLNDGPVTFWLQV
>Mature_145_residues
MIALIQRVTHASVMVDNQLIGEIGAGLLVLLGVERGDDEQKAKRLCDKVLGYRVFSDEEGKMNLNVRQSGGSVLVVSQFT
LAADTQKGMRPGFSRGAAPDEAERLYTHFSDACRASGITTATGCFAADMQVSLLNDGPVTFWLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=39.4557823129252, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=75.1724137931034, Blast_Score=229, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=40.5594405594406, Blast_Score=92, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=36.986301369863, Blast_Score=95, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=39.041095890411, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_EDWI9 (C5BC71)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002935212.1
- GeneID:   7959899
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3858
- OMA:   MKAVIQR
- ProtClustDB:   CLSK2813751
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15622; Mature: 15622

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVTHASVMVDNQLIGEIGAGLLVLLGVERGDDEQKAKRLCDKVLGYRVFSDEEG
CHHHHHHHHHHHHEECHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEECCCCC
KMNLNVRQSGGSVLVVSQFTLAADTQKGMRPGFSRGAAPDEAERLYTHFSDACRASGITT
EEEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
ATGCFAADMQVSLLNDGPVTFWLQV
CCCEEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVTHASVMVDNQLIGEIGAGLLVLLGVERGDDEQKAKRLCDKVLGYRVFSDEEG
CHHHHHHHHHHHHEECHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEECCCCC
KMNLNVRQSGGSVLVVSQFTLAADTQKGMRPGFSRGAAPDEAERLYTHFSDACRASGITT
EEEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
ATGCFAADMQVSLLNDGPVTFWLQV
CCCEEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA