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The map label for this gene is hdfR [H]

Identifier: 238921667

GI number: 238921667

Start: 3703014

End: 3703835

Strand: Direct

Name: hdfR [H]

Synonym: NT01EI_3823

Alternate gene names: 238921667

Gene position: 3703014-3703835 (Clockwise)

Preceding gene: 238921665

Following gene: 238921673

Centisome position: 97.13

GC content: 55.6

Gene sequence:

>822_bases
GTGGATACCGAATTACTCAAAACCTTTCTGGAAGTCAGCCGTACCCGCCACTTTGGTAAAGCGGCCGAATCACTGTACCT
GACACAGTCCGCTGTCAGTTTTCGCATCCGCCAGTTGGAAAATCAAGTAGGTACCGAGCTATTCACTCGCCACCGCAATA
ATATTCAACTTACGCCGGCCGGGCAGACATTAGTGCCCTATGCAGAAAATCTAATGAATACCTGGCTACTGGCCAAGCAG
GAGATGATCAGCGCCCGTCAGCATAAGGCGCTTTCACTGGGAGCTCCAGCATTGCTATGGGAGTCTATGCTGACCGACTG
GCTTGCCCGACTCTACGGCAATAACCCCGCGCAAATGCTAGAGGCCCGCACCGGTCAGCGCCATATCCATATCCGCCAGC
TACACGAGCGCCATCTGGATCTGCTTATCGCAACCGAAATCCCCAAAGCCGATGAATTTATGAGCGAACGGGTCGGTGAA
TTTACGCTGGGGCTCTATACCGCTGGCCAAAGTGCATCGGCACGCCCATTCATCCGCCTCGACTGGGGGGCAGACTTCAG
TCCGCAGCCCTCGACGCTGATCGAGAGTGGCGCTCCCCTGCTGGAGAGTAGCTCACTGCTGATAGCCGAGCGTATTCTGC
GTCAGGTGCACGCCAGCGCGTTTTTACCCATCTCTTGGGCTGCCAGTGACTTACAGCGGCTAACCCACCCAGAAACGCTC
ATAAGGCCGATCTATGCCATCTGGCTGCGCAACAGCGACCGTGTAAATGAGATCCACCCCATGGTACATGATCTGCGCCG
TTTTTTGATGCCGGGTGCCTGA

Upstream 100 bases:

>100_bases
CTATGGCCGTGCTATTTATGGCGCGGAGTATTAGTTAGCCTTGACAAGCTGTAAAACAAAACATTTAAATCATCATGATT
AAAATTTTTATGGATACGCC

Downstream 100 bases:

>100_bases
GGGCACCGGTATTGACGCGATGAAATAACGTCGTACGAAAACGTCGTTAGAGGAAAAACAAAAAAGCCTTCTGTTTTCAC
AGAAGGCTTTTTATCTGGCA

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MDTELLKTFLEVSRTRHFGKAAESLYLTQSAVSFRIRQLENQVGTELFTRHRNNIQLTPAGQTLVPYAENLMNTWLLAKQ
EMISARQHKALSLGAPALLWESMLTDWLARLYGNNPAQMLEARTGQRHIHIRQLHERHLDLLIATEIPKADEFMSERVGE
FTLGLYTAGQSASARPFIRLDWGADFSPQPSTLIESGAPLLESSSLLIAERILRQVHASAFLPISWAASDLQRLTHPETL
IRPIYAIWLRNSDRVNEIHPMVHDLRRFLMPGA

Sequences:

>Translated_273_residues
MDTELLKTFLEVSRTRHFGKAAESLYLTQSAVSFRIRQLENQVGTELFTRHRNNIQLTPAGQTLVPYAENLMNTWLLAKQ
EMISARQHKALSLGAPALLWESMLTDWLARLYGNNPAQMLEARTGQRHIHIRQLHERHLDLLIATEIPKADEFMSERVGE
FTLGLYTAGQSASARPFIRLDWGADFSPQPSTLIESGAPLLESSSLLIAERILRQVHASAFLPISWAASDLQRLTHPETL
IRPIYAIWLRNSDRVNEIHPMVHDLRRFLMPGA
>Mature_273_residues
MDTELLKTFLEVSRTRHFGKAAESLYLTQSAVSFRIRQLENQVGTELFTRHRNNIQLTPAGQTLVPYAENLMNTWLLAKQ
EMISARQHKALSLGAPALLWESMLTDWLARLYGNNPAQMLEARTGQRHIHIRQLHERHLDLLIATEIPKADEFMSERVGE
FTLGLYTAGQSASARPFIRLDWGADFSPQPSTLIESGAPLLESSSLLIAERILRQVHASAFLPISWAASDLQRLTHPETL
IRPIYAIWLRNSDRVNEIHPMVHDLRRFLMPGA

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=273, Percent_Identity=53.8461538461538, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI2367136, Length=164, Percent_Identity=32.9268292682927, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788626, Length=150, Percent_Identity=31.3333333333333, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31078; Mature: 31078

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTELLKTFLEVSRTRHFGKAAESLYLTQSAVSFRIRQLENQVGTELFTRHRNNIQLTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GQTLVPYAENLMNTWLLAKQEMISARQHKALSLGAPALLWESMLTDWLARLYGNNPAQML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
EARTGQRHIHIRQLHERHLDLLIATEIPKADEFMSERVGEFTLGLYTAGQSASARPFIRL
HHHCCCCHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEEE
DWGADFSPQPSTLIESGAPLLESSSLLIAERILRQVHASAFLPISWAASDLQRLTHPETL
ECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHH
IRPIYAIWLRNSDRVNEIHPMVHDLRRFLMPGA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDTELLKTFLEVSRTRHFGKAAESLYLTQSAVSFRIRQLENQVGTELFTRHRNNIQLTPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GQTLVPYAENLMNTWLLAKQEMISARQHKALSLGAPALLWESMLTDWLARLYGNNPAQML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
EARTGQRHIHIRQLHERHLDLLIATEIPKADEFMSERVGEFTLGLYTAGQSASARPFIRL
HHHCCCCHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCCCCEEEE
DWGADFSPQPSTLIESGAPLLESSSLLIAERILRQVHASAFLPISWAASDLQRLTHPETL
ECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHH
IRPIYAIWLRNSDRVNEIHPMVHDLRRFLMPGA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA