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The map label for this gene is aroQ

Identifier: 238921355

GI number: 238921355

Start: 3395872

End: 3396321

Strand: Direct

Name: aroQ

Synonym: NT01EI_3499

Alternate gene names: 238921355

Gene position: 3395872-3396321 (Clockwise)

Preceding gene: 238921354

Following gene: 238921356

Centisome position: 89.08

GC content: 57.56

Gene sequence:

>450_bases
ATGGCAGATAAATTCAACATTTTGCTTCTTAACGGCCCCAATCTGAATATGCTGGGCGTCCGCGAGCCGGAGAAATATGG
CACCCTGACGCTGGCGCAGATTGCGGCGCGCCTGGATCGGCGTGCGCAGGCGCTCGGCGTTTCGCTGCACCATATTCAGT
CCAATGCAGAGCATGAGCTGATCGCCCAGATCCATGCCGCGTTTGGCAATACCGATTTTATTCTGGTTAATCCGGCAGCG
TTTACCCATACCAGTGTAGCGCTGCGCGATGCCCTGTTGGCGGTGCAGATCCCGTTTATCGAGATCCACCTGTCCAACGT
GCACGCCCGGGAGCCGTTCCGCCACCACTCCTATCTGTCCGATATCGCCGTGGGGGTCATTTGCGGTCTGGGCGCCGAGG
GGTATGAATATGCCCTGCAGGCGGCGGTTAATCGCCTGAACAAATCATGA

Upstream 100 bases:

>100_bases
TACGCCGATCGATGCCACAAATTGGCAGAGAAAGAGTGACAACGTGGCGACATCGGGTTATTTTGGCAAAATTCGTCTGA
TTGCCGGAGATAGCAGCACA

Downstream 100 bases:

>100_bases
TAAACAGGGATATGCGTCCGTCTGCCGCGGCGCGCGTCCACAATCTTCGTAACAACAACGAGTACGGAATCACACATGGA
TATTCGTAAAATCAAGAAAC

Product: 3-dehydroquinate dehydratase, type II

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MADKFNILLLNGPNLNMLGVREPEKYGTLTLAQIAARLDRRAQALGVSLHHIQSNAEHELIAQIHAAFGNTDFILVNPAA
FTHTSVALRDALLAVQIPFIEIHLSNVHAREPFRHHSYLSDIAVGVICGLGAEGYEYALQAAVNRLNKS

Sequences:

>Translated_149_residues
MADKFNILLLNGPNLNMLGVREPEKYGTLTLAQIAARLDRRAQALGVSLHHIQSNAEHELIAQIHAAFGNTDFILVNPAA
FTHTSVALRDALLAVQIPFIEIHLSNVHAREPFRHHSYLSDIAVGVICGLGAEGYEYALQAAVNRLNKS
>Mature_148_residues
ADKFNILLLNGPNLNMLGVREPEKYGTLTLAQIAARLDRRAQALGVSLHHIQSNAEHELIAQIHAAFGNTDFILVNPAAF
THTSVALRDALLAVQIPFIEIHLSNVHAREPFRHHSYLSDIAVGVICGLGAEGYEYALQAAVNRLNKS

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_EDWI9 (C5BEW3)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934870.1
- GeneID:   7962497
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3499
- OMA:   TFQSNHE
- ProtClustDB:   CLSK2813647
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16313; Mature: 16182

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 26-26 ACT_SITE 103-103 BINDING 77-77 BINDING 83-83 BINDING 90-90 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKFNILLLNGPNLNMLGVREPEKYGTLTLAQIAARLDRRAQALGVSLHHIQSNAEHEL
CCCCEEEEEEECCCCCEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IAQIHAAFGNTDFILVNPAAFTHTSVALRDALLAVQIPFIEIHLSNVHAREPFRHHSYLS
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCCHHHHHHHH
DIAVGVICGLGAEGYEYALQAAVNRLNKS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADKFNILLLNGPNLNMLGVREPEKYGTLTLAQIAARLDRRAQALGVSLHHIQSNAEHEL
CCCEEEEEEECCCCCEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IAQIHAAFGNTDFILVNPAAFTHTSVALRDALLAVQIPFIEIHLSNVHAREPFRHHSYLS
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCCHHHHHHHH
DIAVGVICGLGAEGYEYALQAAVNRLNKS
HHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA