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The map label for this gene is ampH [H]

Identifier: 238921308

GI number: 238921308

Start: 3341263

End: 3342414

Strand: Direct

Name: ampH [H]

Synonym: NT01EI_3452

Alternate gene names: 238921308

Gene position: 3341263-3342414 (Clockwise)

Preceding gene: 238921307

Following gene: 238921311

Centisome position: 87.64

GC content: 64.58

Gene sequence:

>1152_bases
ATGGATACTCCTTTTCGCTCGTTGTTTCCGCTGGCCGCGCTGGCCATCGGCTGTATGCTGAGCAGCATTTCCGCCCAAGC
CGCCGTACCGGATGCCCAGATCCGCGCGACCGTTGATCGTTACGCCGAGCATATCTTTTATAACAGCGGCGCCACCGGCA
TGGCGCTGGTCGCCATCGACGGCAGGGAGCAGCTGTTCCGCAGCTACGGTGAGACCAAGCCGGGTAACCATCAGCGCCCG
CGCCCCGACTCACTGATCCGTATCGCCTCGCTGACCAAGCTGATGACCAGTGAAGTCCTGGTCAAACTGGATGCAGAGGG
TAAGGTCAAGCTGACCGATCCCCTGTCACGCTATGCTCCGTCAGGTAAGCGGGTGCCCACCAACGCCTCCGGCAGACCGA
TCCGCCTGATGCATCTGGCCTCCCATACCAGCGGCCTGCCGCGCGAGCAGCCGGGCGGTGCCGCCAATCGGACAGTGTTC
ACCTGGCCGACCTATAGCCAGCGCTGGCAGTGGCTGCAGAGCGCACGCCTGAGCGTAGCCCCGGGCAGCAGCGCCGCCTA
TTCTAATCTGGCCTACGATCTGCTGGCCGACGCGCTGGCCCACGCCACCAGGCAGAGCTACCCGGCACTGTTCCAGCGCC
TGATCGCCCGCCCGCTGGGAATGAGCAGCACCACCTATACCCCGACGGCGACACAGTGCGCACGCCTGATGATCCCGGCG
CGCAGCGCCAGCCCGTGTGTCTCCTCACTGGCGGCCATCGGCAGCGGCGGCGTCTACTCCACGCCGGACGACATGCGCCG
CTGGATGCAGCAGTTTCTGGCCGGTGGTCAGCAGCCGCGCAGCCCCTATGCCGCACGCCTGCTGAAGATGTACTATCCGC
GCGCCAAGCTGAATCAGGTGAAAGGCATGGATGTGCCGGGCAAGGCCTCCGCCCTGGGGCTGGGGTGGGTGGCGATGGCG
CCACAGGACGGGCACCCGGCCATCATTCAGAAGACCGGCGGCGCCGGTGGCTTTATTACCTATATGGCGCTGATCCCGGA
GAAAAACATCGGAGTCTTCGTGGTGGTTACCCGCAGCGATCTGACCCGCTTTAATAACATGAGCGACGGGGTTAACGATC
TGGTCAGCGCGCTGGCGGCGCAGAAGTCATAG

Upstream 100 bases:

>100_bases
TGGCGGTATTTTTTACAAAATTCCCGGCGAAAAGCGCTGCCGTACAGCTTTGACTGGCATTACTATAGCTATCCTCTTAA
TTCCTTGGCGTTTAAATGAC

Downstream 100 bases:

>100_bases
GCGGAAGTGCGACTCTAAGTAAGCACACGCTTACACTGTATAACCTGAGAGGCGGCGCCGGAGAGGCAGCAAAAAGGGGC
GCCGTAGCTCCCCTTTTCCC

Product: beta-lactam binding protein AmpH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDTPFRSLFPLAALAIGCMLSSISAQAAVPDAQIRATVDRYAEHIFYNSGATGMALVAIDGREQLFRSYGETKPGNHQRP
RPDSLIRIASLTKLMTSEVLVKLDAEGKVKLTDPLSRYAPSGKRVPTNASGRPIRLMHLASHTSGLPREQPGGAANRTVF
TWPTYSQRWQWLQSARLSVAPGSSAAYSNLAYDLLADALAHATRQSYPALFQRLIARPLGMSSTTYTPTATQCARLMIPA
RSASPCVSSLAAIGSGGVYSTPDDMRRWMQQFLAGGQQPRSPYAARLLKMYYPRAKLNQVKGMDVPGKASALGLGWVAMA
PQDGHPAIIQKTGGAGGFITYMALIPEKNIGVFVVVTRSDLTRFNNMSDGVNDLVSALAAQKS

Sequences:

>Translated_383_residues
MDTPFRSLFPLAALAIGCMLSSISAQAAVPDAQIRATVDRYAEHIFYNSGATGMALVAIDGREQLFRSYGETKPGNHQRP
RPDSLIRIASLTKLMTSEVLVKLDAEGKVKLTDPLSRYAPSGKRVPTNASGRPIRLMHLASHTSGLPREQPGGAANRTVF
TWPTYSQRWQWLQSARLSVAPGSSAAYSNLAYDLLADALAHATRQSYPALFQRLIARPLGMSSTTYTPTATQCARLMIPA
RSASPCVSSLAAIGSGGVYSTPDDMRRWMQQFLAGGQQPRSPYAARLLKMYYPRAKLNQVKGMDVPGKASALGLGWVAMA
PQDGHPAIIQKTGGAGGFITYMALIPEKNIGVFVVVTRSDLTRFNNMSDGVNDLVSALAAQKS
>Mature_383_residues
MDTPFRSLFPLAALAIGCMLSSISAQAAVPDAQIRATVDRYAEHIFYNSGATGMALVAIDGREQLFRSYGETKPGNHQRP
RPDSLIRIASLTKLMTSEVLVKLDAEGKVKLTDPLSRYAPSGKRVPTNASGRPIRLMHLASHTSGLPREQPGGAANRTVF
TWPTYSQRWQWLQSARLSVAPGSSAAYSNLAYDLLADALAHATRQSYPALFQRLIARPLGMSSTTYTPTATQCARLMIPA
RSASPCVSSLAAIGSGGVYSTPDDMRRWMQQFLAGGQQPRSPYAARLLKMYYPRAKLNQVKGMDVPGKASALGLGWVAMA
PQDGHPAIIQKTGGAGGFITYMALIPEKNIGVFVVVTRSDLTRFNNMSDGVNDLVSALAAQKS

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI239747261, Length=341, Percent_Identity=28.4457478005865, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI239752721, Length=341, Percent_Identity=28.4457478005865, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI239741085, Length=341, Percent_Identity=28.4457478005865, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786574, Length=377, Percent_Identity=64.1909814323607, Blast_Score=486, Evalue=1e-139,
Organism=Escherichia coli, GI1790593, Length=376, Percent_Identity=24.7340425531915, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 41276; Mature: 41276

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPFRSLFPLAALAIGCMLSSISAQAAVPDAQIRATVDRYAEHIFYNSGATGMALVAID
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEC
GREQLFRSYGETKPGNHQRPRPDSLIRIASLTKLMTSEVLVKLDAEGKVKLTDPLSRYAP
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCHHHHCC
SGKRVPTNASGRPIRLMHLASHTSGLPREQPGGAANRTVFTWPTYSQRWQWLQSARLSVA
CCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEC
PGSSAAYSNLAYDLLADALAHATRQSYPALFQRLIARPLGMSSTTYTPTATQCARLMIPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCC
RSASPCVSSLAAIGSGGVYSTPDDMRRWMQQFLAGGQQPRSPYAARLLKMYYPRAKLNQV
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHC
KGMDVPGKASALGLGWVAMAPQDGHPAIIQKTGGAGGFITYMALIPEKNIGVFVVVTRSD
CCCCCCCCCCCEECCEEEECCCCCCCEEEEECCCCCHHHHHHEECCCCCCCEEEEEECCH
LTRFNNMSDGVNDLVSALAAQKS
HHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDTPFRSLFPLAALAIGCMLSSISAQAAVPDAQIRATVDRYAEHIFYNSGATGMALVAID
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEC
GREQLFRSYGETKPGNHQRPRPDSLIRIASLTKLMTSEVLVKLDAEGKVKLTDPLSRYAP
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCHHHHCC
SGKRVPTNASGRPIRLMHLASHTSGLPREQPGGAANRTVFTWPTYSQRWQWLQSARLSVA
CCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEC
PGSSAAYSNLAYDLLADALAHATRQSYPALFQRLIARPLGMSSTTYTPTATQCARLMIPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCC
RSASPCVSSLAAIGSGGVYSTPDDMRRWMQQFLAGGQQPRSPYAARLLKMYYPRAKLNQV
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHC
KGMDVPGKASALGLGWVAMAPQDGHPAIIQKTGGAGGFITYMALIPEKNIGVFVVVTRSD
CCCCCCCCCCCEECCEEEECCCCCCCEEEEECCCCCHHHHHHEECCCCCCCEEEEEECCH
LTRFNNMSDGVNDLVSALAAQKS
HHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]