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The map label for this gene is engA

Identifier: 238921035

GI number: 238921035

Start: 3046514

End: 3047998

Strand: Reverse

Name: engA

Synonym: NT01EI_3165

Alternate gene names: 238921035

Gene position: 3047998-3046514 (Counterclockwise)

Preceding gene: 238921036

Following gene: 238921034

Centisome position: 79.95

GC content: 59.12

Gene sequence:

>1485_bases
ATGATACCTGTCGTCGCGCTGGTCGGGCGCCCGAATGTGGGGAAATCCACCTTATTCAACCGGTTGACGCGTACCCGCGA
TGCGTTGGTCGCCGACTTCCCCGGATTAACCCGAGATCGCAAGTATGGTCGTGCTGAAGTAAACGGTCACGAGTTTATCA
TTATCGATACCGGCGGTATCGACGGCACCGAAAACGGGGTCGAGACCCACATGGCGGAGCAGTCGCTGATGGCGATTGAA
GAGGCCGATATCGTGCTGTTTCTGGTCGATGCCCGCGATGGCCTGCTGCCGGCGGACGAGGCCATTGCCCGCCATCTGCG
CAGCCGCGATAAGGCGACGTTCCTGGTCGCCAACAAAACCGACGGCATTGACGCCGAGGTGGCCGTCGGGGACTTTTATT
CCCTGGGTATGGGGGAGGTTCACCCTATCGCGGCCTCCCATGGGCGCGGTGTGACCCAGCTTATCGAAGATGCGCTGGTC
CCGTTTATTCCACAGGAAGCGCCGGCACCGGTGCTGAGCGAGGAAGAAGAGAACGCGGCCTACTGGGCGGAGCTGGAGGC
GGAAGCCGACGGCGAGGCACAGGAGGAGGAAGAGGCGTTTGATCCCATCAATCAGCCCATTAAAATTGCGATTGTCGGGC
GTCCCAACGTCGGTAAGTCCACGCTGACCAACCGCATCCTGGGCGAAGACCGGGTGGTGGTGTATGACATGCCGGGCACC
ACCCGCGACAGTATCTATATTCCGATGGAGCGTGACGAGCGCGAATACGTTCTGATCGACACCGCCGGGGTGCGCAAGCG
CGGCAAGGTTACGGATACCGTTGAGAAGTTCTCGGTCATCAAGACGCTGCAGGCGATTGAAGATGCCAACGTGGTGCTGC
TGGTGATCGATGCCCGCCAGGGGATCTCCGATCAGGATCTTTCTCTGCTCGGCTTTATCCTCAATAGTGGGCGCTCACTG
GTGGTGGTGGTCAATAAGTGGGACGGCCTGAGCCTGGAGGTCAAAGAGCAGGTGAAGGATATGCTGGATCTGCGTCTGGG
ATTCGTCGACTTCGCCCGTATCCACTTTATCTCCGCTCTGCACGGCAGCGGTGTGGGCAACCTGTTCGAATCGATTCAGG
AAGCCTACGAAAGTGCCACCCGCCGCGTCAGCACCGCGATGCTGACCCGCATTATGACCATGGCGCAGGATGACCATCAG
CCGCCGATGGTGCGCGGGCGCCGGGTGAAGCTGAAGTATGCGCACGCCGGGGGCTATAACCCACCGATCGTGGTGATCCA
CGGTAACCAGGTGAAGGATCTGCCGGACTCCTACAAGCGCTACCTGATGAACTACTTCCGCCGCTCTTTGAACGTAATGG
GGACGCCGATCCGCATTCAGTTTAAAGAAGGGGATAACCCGTTCGCCAATAAGCGCAACACCCTGACGCCAAACCAGATG
CGCAAGCGTAAGCGTCTGTTGAGCCACCTGAAAAAGACGAAGTAA

Upstream 100 bases:

>100_bases
GGAACGGCTCCTGATGACCTCAGGGGCCGTTTCGTCTTCTGCATATTTTCCCGTCGCCGACGGCGGCGGGGAATGACATT
ACGTAATAGAGGCTTCAACA

Downstream 100 bases:

>100_bases
TCGTTAATAGCGGGACACATTGGTGTCCCGTTTTTTTTGACCCGGTCCTATGTTAGGCTATTTATCGTACCTGTTCTGGG
CGTCCTTGACGCTCATGTTG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVNGHEFIIIDTGGIDGTENGVETHMAEQSLMAIE
EADIVLFLVDARDGLLPADEAIARHLRSRDKATFLVANKTDGIDAEVAVGDFYSLGMGEVHPIAASHGRGVTQLIEDALV
PFIPQEAPAPVLSEEEENAAYWAELEAEADGEAQEEEEAFDPINQPIKIAIVGRPNVGKSTLTNRILGEDRVVVYDMPGT
TRDSIYIPMERDEREYVLIDTAGVRKRGKVTDTVEKFSVIKTLQAIEDANVVLLVIDARQGISDQDLSLLGFILNSGRSL
VVVVNKWDGLSLEVKEQVKDMLDLRLGFVDFARIHFISALHGSGVGNLFESIQEAYESATRRVSTAMLTRIMTMAQDDHQ
PPMVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRRSLNVMGTPIRIQFKEGDNPFANKRNTLTPNQM
RKRKRLLSHLKKTK

Sequences:

>Translated_494_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVNGHEFIIIDTGGIDGTENGVETHMAEQSLMAIE
EADIVLFLVDARDGLLPADEAIARHLRSRDKATFLVANKTDGIDAEVAVGDFYSLGMGEVHPIAASHGRGVTQLIEDALV
PFIPQEAPAPVLSEEEENAAYWAELEAEADGEAQEEEEAFDPINQPIKIAIVGRPNVGKSTLTNRILGEDRVVVYDMPGT
TRDSIYIPMERDEREYVLIDTAGVRKRGKVTDTVEKFSVIKTLQAIEDANVVLLVIDARQGISDQDLSLLGFILNSGRSL
VVVVNKWDGLSLEVKEQVKDMLDLRLGFVDFARIHFISALHGSGVGNLFESIQEAYESATRRVSTAMLTRIMTMAQDDHQ
PPMVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRRSLNVMGTPIRIQFKEGDNPFANKRNTLTPNQM
RKRKRLLSHLKKTK
>Mature_494_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVNGHEFIIIDTGGIDGTENGVETHMAEQSLMAIE
EADIVLFLVDARDGLLPADEAIARHLRSRDKATFLVANKTDGIDAEVAVGDFYSLGMGEVHPIAASHGRGVTQLIEDALV
PFIPQEAPAPVLSEEEENAAYWAELEAEADGEAQEEEEAFDPINQPIKIAIVGRPNVGKSTLTNRILGEDRVVVYDMPGT
TRDSIYIPMERDEREYVLIDTAGVRKRGKVTDTVEKFSVIKTLQAIEDANVVLLVIDARQGISDQDLSLLGFILNSGRSL
VVVVNKWDGLSLEVKEQVKDMLDLRLGFVDFARIHFISALHGSGVGNLFESIQEAYESATRRVSTAMLTRIMTMAQDDHQ
PPMVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRRSLNVMGTPIRIQFKEGDNPFANKRNTLTPNQM
RKRKRLLSHLKKTK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=494, Percent_Identity=82.1862348178138, Blast_Score=827, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=37.8947368421053, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=162, Percent_Identity=34.5679012345679, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_EDWI9 (C5BES7)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934550.1
- GeneID:   7958683
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3165
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54984; Mature: 54984

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVNGHEFIIIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEEECCCC
DGTENGVETHMAEQSLMAIEEADIVLFLVDARDGLLPADEAIARHLRSRDKATFLVANKT
CCCCCCHHHHHHHHHHHHEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECC
DGIDAEVAVGDFYSLGMGEVHPIAASHGRGVTQLIEDALVPFIPQEAPAPVLSEEEENAA
CCCCCEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
YWAELEAEADGEAQEEEEAFDPINQPIKIAIVGRPNVGKSTLTNRILGEDRVVVYDMPGT
EEEEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCC
TRDSIYIPMERDEREYVLIDTAGVRKRGKVTDTVEKFSVIKTLQAIEDANVVLLVIDARQ
CCCCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
GISDQDLSLLGFILNSGRSLVVVVNKWDGLSLEVKEQVKDMLDLRLGFVDFARIHFISAL
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGSGVGNLFESIQEAYESATRRVSTAMLTRIMTMAQDDHQPPMVRGRRVKLKYAHAGGYN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCC
PPIVVIHGNQVKDLPDSYKRYLMNYFRRSLNVMGTPIRIQFKEGDNPFANKRNTLTPNQM
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHH
RKRKRLLSHLKKTK
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVNGHEFIIIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEEECCCC
DGTENGVETHMAEQSLMAIEEADIVLFLVDARDGLLPADEAIARHLRSRDKATFLVANKT
CCCCCCHHHHHHHHHHHHEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECC
DGIDAEVAVGDFYSLGMGEVHPIAASHGRGVTQLIEDALVPFIPQEAPAPVLSEEEENAA
CCCCCEEEECCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
YWAELEAEADGEAQEEEEAFDPINQPIKIAIVGRPNVGKSTLTNRILGEDRVVVYDMPGT
EEEEEECCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCC
TRDSIYIPMERDEREYVLIDTAGVRKRGKVTDTVEKFSVIKTLQAIEDANVVLLVIDARQ
CCCCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
GISDQDLSLLGFILNSGRSLVVVVNKWDGLSLEVKEQVKDMLDLRLGFVDFARIHFISAL
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGSGVGNLFESIQEAYESATRRVSTAMLTRIMTMAQDDHQPPMVRGRRVKLKYAHAGGYN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCC
PPIVVIHGNQVKDLPDSYKRYLMNYFRRSLNVMGTPIRIQFKEGDNPFANKRNTLTPNQM
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHH
RKRKRLLSHLKKTK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA