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The map label for this gene is cysS

Identifier: 238920879

GI number: 238920879

Start: 2892951

End: 2894336

Strand: Reverse

Name: cysS

Synonym: NT01EI_3006

Alternate gene names: 238920879

Gene position: 2894336-2892951 (Counterclockwise)

Preceding gene: 238920882

Following gene: 238920874

Centisome position: 75.92

GC content: 61.04

Gene sequence:

>1386_bases
ATGCTTAAAATCTTTAATACACTCAGTCGCCAGAAAGAGGAATTTAAACCCATCCATGCCGGTGAAGTCGGTATGTATGT
GTGTGGGGTAACCATTTACGACCTGTGTCACATCGGTCACGGCCGTACCTTTGTCTGTTTCGACGTGGTGGCCCGCTACC
TGCGCTATCTGGGCTACAGGCTGAAGTATGTGCGTAACGTCACCGATGTGGACGATAAAATCATCAAGCGTGCGCTGGAG
AACCAAGAGAGCTGTGAGCAGCTGACCGAGCGTATGCTGGCAGAGATGCATCGCGATTTCGATGCCCTGAATATCGCCCG
TCCCGACGTAGAGCCGCGGGCGACCCACCATATCGCCGAGATCATCGCGCTGGTGGAGCAGCTGATCGCCCGCGATCATG
CCTATGTGGCCAGCAACGGCGACGTGATGTTCGCCGTCGATACCGATCCGGACTACGGCGTGCTGTCGCGTCAGGATCTG
GAGCAGCTGCAGGCCGGTGCGCGGGTGGAGGTGGCCGACGTGAAGCGCAACCCGATGGACTTTGTGCTGTGGAAGATGTC
CAAGCCGGGCGAGCCGAGCTGGCCGTCACCGTGGGGCGAAGGGCGTCCCGGCTGGCACATCGAGTGCTCGGCGATGAACT
GCAAGCAGCTGGGATCGCACTTTGATATTCACGGCGGTGGCTCGGATCTGATGTTCCCGCACCATGAAAACGAGATCGCC
CAGTCGACCTGCGCCCACGACGGCGCCTACGTCAACTGCTGGATGCACTCTGGCATGGTGATGATCGATCGCGAGAAGAT
GTCCAAGTCGCTGGGCAACTTCTTCACCATTCGCGACGTGTTGGCGCACTATGACGCGGAGACGGTGCGTTACTTCCTGA
TGTCCGGCCACTACCGCAGCCAGCTGAACTACAGCGAAGAGAACCTGAAGCAGGCGCGTGCGGCGCTGGAGCGTCTGTAT
ACCGCGTTGCGCGGTACCGATGTCGCGGCGCAGCCGACGGCAGATGAGACCTTTACCACTCGCTTCCGGGCGGCGATGGA
TGATGACTTCAACACGCCGGAGGCCTACTCGGTACTGTTTGACATGGCGCGTGAGATCAACCGCCTGAAAGGGGAAGATA
TGGCGCAGGCGAATGCGCTGGCGGCCCAGATGCGCGGTCTGGCCCACGTACTGGGGCTGTTGGAGCAGACGCCGGAGCAC
TTCCTGCAGAGCGGCGCCGCGGCAGGCGATGACGAGGTTGCGCAGATCGAGGCGCTGATCAGGCAGCGCAACGACGCCCG
CGCCGCCAAGGCATGGGCGCTTGCCGATGAGGCGCGTGACAGCCTGAATGCGATGGGGATCGTGCTGGAGGATGGGCCGC
AGGGTACCACCTGGCGGCGTAAGTAA

Upstream 100 bases:

>100_bases
TCGCCGGGCGCCGCTCCCGGGCTTCATTCTCTCCGGGCGCTGCGTTAGTATAACCTTTACGTTTTTATCCTGTTATCAGC
AACTATCACGGATACCCCCG

Downstream 100 bases:

>100_bases
GGCCGGGCGATAATGCGCAAAAAGCCGGACCCGGGTCCGGCTTTTTTACGTCTGGCGTTCAGCTTAGGCGATGACGCGCG
CCTGCTGCCCGGCGAAGTCG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MLKIFNTLSRQKEEFKPIHAGEVGMYVCGVTIYDLCHIGHGRTFVCFDVVARYLRYLGYRLKYVRNVTDVDDKIIKRALE
NQESCEQLTERMLAEMHRDFDALNIARPDVEPRATHHIAEIIALVEQLIARDHAYVASNGDVMFAVDTDPDYGVLSRQDL
EQLQAGARVEVADVKRNPMDFVLWKMSKPGEPSWPSPWGEGRPGWHIECSAMNCKQLGSHFDIHGGGSDLMFPHHENEIA
QSTCAHDGAYVNCWMHSGMVMIDREKMSKSLGNFFTIRDVLAHYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLY
TALRGTDVAAQPTADETFTTRFRAAMDDDFNTPEAYSVLFDMAREINRLKGEDMAQANALAAQMRGLAHVLGLLEQTPEH
FLQSGAAAGDDEVAQIEALIRQRNDARAAKAWALADEARDSLNAMGIVLEDGPQGTTWRRK

Sequences:

>Translated_461_residues
MLKIFNTLSRQKEEFKPIHAGEVGMYVCGVTIYDLCHIGHGRTFVCFDVVARYLRYLGYRLKYVRNVTDVDDKIIKRALE
NQESCEQLTERMLAEMHRDFDALNIARPDVEPRATHHIAEIIALVEQLIARDHAYVASNGDVMFAVDTDPDYGVLSRQDL
EQLQAGARVEVADVKRNPMDFVLWKMSKPGEPSWPSPWGEGRPGWHIECSAMNCKQLGSHFDIHGGGSDLMFPHHENEIA
QSTCAHDGAYVNCWMHSGMVMIDREKMSKSLGNFFTIRDVLAHYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLY
TALRGTDVAAQPTADETFTTRFRAAMDDDFNTPEAYSVLFDMAREINRLKGEDMAQANALAAQMRGLAHVLGLLEQTPEH
FLQSGAAAGDDEVAQIEALIRQRNDARAAKAWALADEARDSLNAMGIVLEDGPQGTTWRRK
>Mature_461_residues
MLKIFNTLSRQKEEFKPIHAGEVGMYVCGVTIYDLCHIGHGRTFVCFDVVARYLRYLGYRLKYVRNVTDVDDKIIKRALE
NQESCEQLTERMLAEMHRDFDALNIARPDVEPRATHHIAEIIALVEQLIARDHAYVASNGDVMFAVDTDPDYGVLSRQDL
EQLQAGARVEVADVKRNPMDFVLWKMSKPGEPSWPSPWGEGRPGWHIECSAMNCKQLGSHFDIHGGGSDLMFPHHENEIA
QSTCAHDGAYVNCWMHSGMVMIDREKMSKSLGNFFTIRDVLAHYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLY
TALRGTDVAAQPTADETFTTRFRAAMDDDFNTPEAYSVLFDMAREINRLKGEDMAQANALAAQMRGLAHVLGLLEQTPEH
FLQSGAAAGDDEVAQIEALIRQRNDARAAKAWALADEARDSLNAMGIVLEDGPQGTTWRRK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=386, Percent_Identity=38.3419689119171, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI10835051, Length=233, Percent_Identity=43.3476394849785, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI62240992, Length=233, Percent_Identity=43.3476394849785, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI303304987, Length=233, Percent_Identity=43.3476394849785, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI21269877, Length=233, Percent_Identity=43.3476394849785, Blast_Score=192, Evalue=6e-49,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=83.2971800433839, Blast_Score=794, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509797, Length=242, Percent_Identity=40.495867768595, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17509795, Length=242, Percent_Identity=40.495867768595, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324082, Length=336, Percent_Identity=33.3333333333333, Blast_Score=186, Evalue=5e-48,
Organism=Drosophila melanogaster, GI19922218, Length=500, Percent_Identity=35, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI19922364, Length=232, Percent_Identity=40.948275862069, Blast_Score=172, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_EDWI9 (C5B8V6)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934394.1
- GeneID:   7960284
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3006
- OMA:   DFDALNM
- ProtClustDB:   CLSK2813528
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 52049; Mature: 52049

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 269-269

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIFNTLSRQKEEFKPIHAGEVGMYVCGVTIYDLCHIGHGRTFVCFDVVARYLRYLGYR
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
LKYVRNVTDVDDKIIKRALENQESCEQLTERMLAEMHRDFDALNIARPDVEPRATHHIAE
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHH
IIALVEQLIARDHAYVASNGDVMFAVDTDPDYGVLSRQDLEQLQAGARVEVADVKRNPMD
HHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCC
FVLWKMSKPGEPSWPSPWGEGRPGWHIECSAMNCKQLGSHFDIHGGGSDLMFPHHENEIA
EEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCEEECCCCCCCCCCCCCHHHH
QSTCAHDGAYVNCWMHSGMVMIDREKMSKSLGNFFTIRDVLAHYDAETVRYFLMSGHYRS
HHHHCCCCCEEEEEECCCEEEEEHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCHHH
QLNYSEENLKQARAALERLYTALRGTDVAAQPTADETFTTRFRAAMDDDFNTPEAYSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
DMAREINRLKGEDMAQANALAAQMRGLAHVLGLLEQTPEHFLQSGAAAGDDEVAQIEALI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHH
RQRNDARAAKAWALADEARDSLNAMGIVLEDGPQGTTWRRK
HHCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLKIFNTLSRQKEEFKPIHAGEVGMYVCGVTIYDLCHIGHGRTFVCFDVVARYLRYLGYR
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
LKYVRNVTDVDDKIIKRALENQESCEQLTERMLAEMHRDFDALNIARPDVEPRATHHIAE
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHH
IIALVEQLIARDHAYVASNGDVMFAVDTDPDYGVLSRQDLEQLQAGARVEVADVKRNPMD
HHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCC
FVLWKMSKPGEPSWPSPWGEGRPGWHIECSAMNCKQLGSHFDIHGGGSDLMFPHHENEIA
EEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCCEEECCCCCCCCCCCCCHHHH
QSTCAHDGAYVNCWMHSGMVMIDREKMSKSLGNFFTIRDVLAHYDAETVRYFLMSGHYRS
HHHHCCCCCEEEEEECCCEEEEEHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCHHH
QLNYSEENLKQARAALERLYTALRGTDVAAQPTADETFTTRFRAAMDDDFNTPEAYSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
DMAREINRLKGEDMAQANALAAQMRGLAHVLGLLEQTPEHFLQSGAAAGDDEVAQIEALI
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHHHHH
RQRNDARAAKAWALADEARDSLNAMGIVLEDGPQGTTWRRK
HHCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA