BacMap

Definition	Edwardsiella ictaluri 93-146 chromosome, complete genome.
Accession	NC_012779
Length	3,812,315

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The map label for this gene is caiD [H]

Identifier: 238920830

GI number: 238920830

Start: 2844004

End: 2844789

Strand: Reverse

Name: caiD [H]

Synonym: NT01EI_2956

Alternate gene names: 238920830

Gene position: 2844789-2844004 (Counterclockwise)

Preceding gene: 238920831

Following gene: 238920829

Centisome position: 74.62

GC content: 66.16

Gene sequence:

>786_bases
ATGAGCGAGTCATTACAGATAGCGCGCAACGGTGGAGTTCTGGAAATTACGCTGAACCGCCCCAAGGCCAATGCCATCGA
TGCCAAGACCAGTCTGGCCATGGGGGAGGCGTTTATCGCTTTCCGCGACGATCCGACGCTGCGGGTCGCCATCATTACCG
GCGCCGGCGGACGCTTTTTCTCCGCCGGCTGGGATCTGAAGGCGGCGGCGGAGGGCGAGGCGCCGGATGCCGACTTTGGC
CCGGGCGGCTTTGCCGGCTTGACGGAGCTGTTCAACCTGGATAAGCCGGTGATTGCCGCGGTCAACGGCTACGCCTTTGG
CGGCGGCTTTGAGCTGGCGCTGGCGGCAGACATGATCGTCTGCGCCGACAATGCCTGTTTCGCCCTGCCGGAAGCCAGGC
TGGGGATCGTCCCGGACAGCGGCGGCATGCTGCGTCTGCCCAAGTGCATTCCGCCGGCGATCGCCAACGAGATGATGATG
AGCGGGCGCCGTATGGAGGCCGAAGAGGCGTTGCGCTGGGGGATCGTCAATCAGGTGGTTCCGGGCGATCGGCTGATGGA
GACGGCGCGGGCGCTGGCCCAGCAGGTGGCGGAGAGCGCACCGCTGGCGCTGGCAGCGCTGAAGGAGATTGTCCGCGCCA
CCGCAGAGCTGTCCGTCGAGGAGGGCTATCGCCTGATCCGCAGCGGCGCCCTGAAGCACTATCCGGCCGTGCTGCATTCG
GAGGATGCGCTGGAGGGGCCACAGGCCTTTGCCGAAAAACGCGAGCCGGTCTGGAAGGGGCGCTGA

Upstream 100 bases:

>100_bases
AAAAGTTTATGTTAATCCGCACCGGGGGCCGGCGTACGCCGCCAGCCCTGTGGCTACGCGCCGGTGCGATCACCCTGTTG
AATCGGAATGGAGTATGAGG

Downstream 100 bases:

>100_bases
GCGCCGTGAAGTGACTGTGTGGCTGAGACCGTAGACGGAGGGCTTTTCCCCTCCGTCTTTTTTTGGGCATCGGTGAAGGG
AGTACGGGCATATTCCGCAC

Product: carnitinyl-CoA dehydratase

Products: L-Carnitine.; L-carnitinyl-CoA [C]

Alternate protein names: Crotonobetainyl-CoA hydratase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSESLQIARNGGVLEITLNRPKANAIDAKTSLAMGEAFIAFRDDPTLRVAIITGAGGRFFSAGWDLKAAAEGEAPDADFG
PGGFAGLTELFNLDKPVIAAVNGYAFGGGFELALAADMIVCADNACFALPEARLGIVPDSGGMLRLPKCIPPAIANEMMM
SGRRMEAEEALRWGIVNQVVPGDRLMETARALAQQVAESAPLALAALKEIVRATAELSVEEGYRLIRSGALKHYPAVLHS
EDALEGPQAFAEKREPVWKGR

Sequences:

>Translated_261_residues
MSESLQIARNGGVLEITLNRPKANAIDAKTSLAMGEAFIAFRDDPTLRVAIITGAGGRFFSAGWDLKAAAEGEAPDADFG
PGGFAGLTELFNLDKPVIAAVNGYAFGGGFELALAADMIVCADNACFALPEARLGIVPDSGGMLRLPKCIPPAIANEMMM
SGRRMEAEEALRWGIVNQVVPGDRLMETARALAQQVAESAPLALAALKEIVRATAELSVEEGYRLIRSGALKHYPAVLHS
EDALEGPQAFAEKREPVWKGR
>Mature_260_residues
SESLQIARNGGVLEITLNRPKANAIDAKTSLAMGEAFIAFRDDPTLRVAIITGAGGRFFSAGWDLKAAAEGEAPDADFGP
GGFAGLTELFNLDKPVIAAVNGYAFGGGFELALAADMIVCADNACFALPEARLGIVPDSGGMLRLPKCIPPAIANEMMMS
GRRMEAEEALRWGIVNQVVPGDRLMETARALAQQVAESAPLALAALKEIVRATAELSVEEGYRLIRSGALKHYPAVLHSE
DALEGPQAFAEKREPVWKGR

Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=35.4330708661417, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI70995211, Length=269, Percent_Identity=33.0855018587361, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI68989263, Length=184, Percent_Identity=35.8695652173913, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=29.2, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4502327, Length=257, Percent_Identity=31.9066147859922, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI45643119, Length=225, Percent_Identity=29.7777777777778, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI260275230, Length=225, Percent_Identity=29.7777777777778, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI260274832, Length=225, Percent_Identity=29.7777777777778, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI150378541, Length=255, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI37594469, Length=189, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI37594471, Length=189, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI221136756, Length=135, Percent_Identity=30.3703703703704, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI221136753, Length=135, Percent_Identity=30.3703703703704, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI221307494, Length=135, Percent_Identity=30.3703703703704, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4757966, Length=136, Percent_Identity=28.6764705882353, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI51538581, Length=136, Percent_Identity=28.6764705882353, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI25453481, Length=136, Percent_Identity=28.6764705882353, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI51538573, Length=136, Percent_Identity=28.6764705882353, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI20127408, Length=177, Percent_Identity=27.683615819209, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI213417737, Length=227, Percent_Identity=28.6343612334802, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI157694516, Length=227, Percent_Identity=28.6343612334802, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4757968, Length=223, Percent_Identity=25.1121076233184, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI49355787, Length=223, Percent_Identity=25.1121076233184, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=81.2260536398467, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=40.530303030303, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787660, Length=256, Percent_Identity=33.59375, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082183, Length=223, Percent_Identity=30.0448430493274, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788682, Length=194, Percent_Identity=35.0515463917526, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=30.8, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790281, Length=252, Percent_Identity=29.3650793650794, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=258, Percent_Identity=35.2713178294574, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17554946, Length=257, Percent_Identity=34.2412451361868, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17560910, Length=257, Percent_Identity=31.1284046692607, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17549921, Length=231, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=221, Percent_Identity=29.8642533936652, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=266, Percent_Identity=26.6917293233083, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=257, Percent_Identity=29.1828793774319, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=259, Percent_Identity=25.0965250965251, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=220, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=217, Percent_Identity=24.8847926267281, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=36.4372469635627, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=36.4372469635627, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24653139, Length=267, Percent_Identity=33.7078651685393, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19920382, Length=230, Percent_Identity=32.1739130434783, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19922422, Length=265, Percent_Identity=28.6792452830189, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357171, Length=207, Percent_Identity=31.8840579710145, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650670, Length=197, Percent_Identity=34.5177664974619, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24654903, Length=214, Percent_Identity=26.1682242990654, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24583165, Length=226, Percent_Identity=25.6637168141593, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28571729, Length=179, Percent_Identity=29.0502793296089, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571730, Length=179, Percent_Identity=29.0502793296089, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19921018, Length=205, Percent_Identity=26.3414634146341, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022852
- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 27665; Mature: 27534

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESLQIARNGGVLEITLNRPKANAIDAKTSLAMGEAFIAFRDDPTLRVAIITGAGGRFF
CCCCCEEECCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEECCCCCEEEEEEECCCCCEE
SAGWDLKAAAEGEAPDADFGPGGFAGLTELFNLDKPVIAAVNGYAFGGGFELALAADMIV
ECCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCEEECCCEEHHHHHCEEE
CADNACFALPEARLGIVPDSGGMLRLPKCIPPAIANEMMMSGRRMEAEEALRWGIVNQVV
ECCCCEEECCCCCEEEEECCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PGDRLMETARALAQQVAESAPLALAALKEIVRATAELSVEEGYRLIRSGALKHYPAVLHS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCC
EDALEGPQAFAEKREPVWKGR
CHHCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SESLQIARNGGVLEITLNRPKANAIDAKTSLAMGEAFIAFRDDPTLRVAIITGAGGRFF
CCCCEEECCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEECCCCCEEEEEEECCCCCEE
SAGWDLKAAAEGEAPDADFGPGGFAGLTELFNLDKPVIAAVNGYAFGGGFELALAADMIV
ECCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEECCEEECCCEEHHHHHCEEE
CADNACFALPEARLGIVPDSGGMLRLPKCIPPAIANEMMMSGRRMEAEEALRWGIVNQVV
ECCCCEEECCCCCEEEEECCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PGDRLMETARALAQQVAESAPLALAALKEIVRATAELSVEEGYRLIRSGALKHYPAVLHS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCC
EDALEGPQAFAEKREPVWKGR
CHHCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Carnitine; D-carnitinyl-CoA [C]

Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA