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The map label for this gene is gpmA

Identifier: 238920733

GI number: 238920733

Start: 2738763

End: 2739515

Strand: Direct

Name: gpmA

Synonym: NT01EI_2846

Alternate gene names: 238920733

Gene position: 2738763-2739515 (Clockwise)

Preceding gene: 238920731

Following gene: 238920735

Centisome position: 71.84

GC content: 60.16

Gene sequence:

>753_bases
ATGGCTGTCACTAAACTGGTTCTGCTCCGCCACGGCGAAAGCGAATGGAACCGGGAAAACCGCTTCACCGGCTGGACCGA
CGTTGAACTGTCAGAGAAGGGGCGCCAGGAGGCACTGGCAGCAGGCCGTCTTCTGAAGGCGCAGGGATTTTCCTTTGACA
TCGCCTACACCTCCGTGCTTAAACGTGCCATTCATACTCTGTGGCACGTACTGGATAAGCTCGATCAGCCGTGGCTGCCG
GTGGAGAAGTCATGGAAGCTCAATGAGCGTCACTATGGCGCTCTGCAGGGACTGAACAAGGCAGAGACCGCGCAGCAGTA
CGGCGATGAACAGGTCAAGCTATGGCGCCGCGCCTTTGCCATCACCCCGCCGGCCCTGACGCCGGACGATCCCCGCTATC
CCGGTCACGATCCGCGCTATGCGGCCCTGAGCGCCGACGAACTCCCGCTGACCGAGAGCCTGGCCACCACCATTGAACGG
GTGATCCCCTATTGGCAGCAGCAGATAGCACCACGTATCTCCGCCGGTGAGCGGATCATCATCGCCGCCCATGGCAATTC
GCTGCGCGCGCTGGTAAAGCATCTGGATCACCTGAGCGAAGGCGAGATTGTCGAGCTGAATATCCCGACCGGCGTTCCGC
TGGTATATGAGTTCGACAAAAATATGCGGCCGCTGCATCATTATTATCTCGGCGACGCCACCGAGATTGCCGCCCGCCAA
AGCGCCGTCGCCAATCAGGGCAAGGCAGGCTAA

Upstream 100 bases:

>100_bases
GCGGTCGGAGAAAAGCGCCAGACGTGCGCCGGGTTATTGCATTCCACACACTATAATGATAATAATTATCATTATAGTGT
CGTAATTAAGGAGTCTCACT

Downstream 100 bases:

>100_bases
CCTAGCCCGCCTTCTTAACTCCGCCACGGCGCCGGGCTCCGTGGCGGCCAGCGCACCTAGGCGGTTAGCCGTGTCCGGCG
CGCGCGTACCGCGTCGGCCA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAVTKLVLLRHGESEWNRENRFTGWTDVELSEKGRQEALAAGRLLKAQGFSFDIAYTSVLKRAIHTLWHVLDKLDQPWLP
VEKSWKLNERHYGALQGLNKAETAQQYGDEQVKLWRRAFAITPPALTPDDPRYPGHDPRYAALSADELPLTESLATTIER
VIPYWQQQIAPRISAGERIIIAAHGNSLRALVKHLDHLSEGEIVELNIPTGVPLVYEFDKNMRPLHHYYLGDATEIAARQ
SAVANQGKAG

Sequences:

>Translated_250_residues
MAVTKLVLLRHGESEWNRENRFTGWTDVELSEKGRQEALAAGRLLKAQGFSFDIAYTSVLKRAIHTLWHVLDKLDQPWLP
VEKSWKLNERHYGALQGLNKAETAQQYGDEQVKLWRRAFAITPPALTPDDPRYPGHDPRYAALSADELPLTESLATTIER
VIPYWQQQIAPRISAGERIIIAAHGNSLRALVKHLDHLSEGEIVELNIPTGVPLVYEFDKNMRPLHHYYLGDATEIAARQ
SAVANQGKAG
>Mature_249_residues
AVTKLVLLRHGESEWNRENRFTGWTDVELSEKGRQEALAAGRLLKAQGFSFDIAYTSVLKRAIHTLWHVLDKLDQPWLPV
EKSWKLNERHYGALQGLNKAETAQQYGDEQVKLWRRAFAITPPALTPDDPRYPGHDPRYAALSADELPLTESLATTIERV
IPYWQQQIAPRISAGERIIIAAHGNSLRALVKHLDHLSEGEIVELNIPTGVPLVYEFDKNMRPLHHYYLGDATEIAARQS
AVANQGKAG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=252, Percent_Identity=55.1587301587302, Blast_Score=291, Evalue=3e-79,
Organism=Homo sapiens, GI4505753, Length=252, Percent_Identity=56.3492063492063, Blast_Score=284, Evalue=5e-77,
Organism=Homo sapiens, GI71274132, Length=252, Percent_Identity=53.968253968254, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI4502445, Length=254, Percent_Identity=48.4251968503937, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI40353764, Length=254, Percent_Identity=48.4251968503937, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=57.5757575757576, Blast_Score=185, Evalue=3e-47,
Organism=Escherichia coli, GI1786970, Length=249, Percent_Identity=79.1164658634538, Blast_Score=407, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=52.0325203252033, Blast_Score=253, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6324516, Length=283, Percent_Identity=32.5088339222615, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=29.7658862876254, Blast_Score=127, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24646216, Length=249, Percent_Identity=51.8072289156626, Blast_Score=270, Evalue=9e-73,
Organism=Drosophila melanogaster, GI85725270, Length=249, Percent_Identity=53.8152610441767, Blast_Score=261, Evalue=3e-70,
Organism=Drosophila melanogaster, GI85725272, Length=249, Percent_Identity=53.8152610441767, Blast_Score=261, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24650981, Length=249, Percent_Identity=53.8152610441767, Blast_Score=261, Evalue=3e-70,
Organism=Drosophila melanogaster, GI28571817, Length=250, Percent_Identity=39.6, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28571815, Length=250, Percent_Identity=39.6, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24648979, Length=250, Percent_Identity=39.6, Blast_Score=178, Evalue=3e-45,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_EDWI9 (C5BEL3)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934248.1
- ProteinModelPortal:   C5BEL3
- GeneID:   7959494
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2846
- OMA:   TGWKDPD
- ProtClustDB:   PRK14115
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 28214; Mature: 28083

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 11-11 ACT_SITE 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTKLVLLRHGESEWNRENRFTGWTDVELSEKGRQEALAAGRLLKAQGFSFDIAYTSVL
CCHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHH
KRAIHTLWHVLDKLDQPWLPVEKSWKLNERHYGALQGLNKAETAQQYGDEQVKLWRRAFA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHH
ITPPALTPDDPRYPGHDPRYAALSADELPLTESLATTIERVIPYWQQQIAPRISAGERII
CCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IAAHGNSLRALVKHLDHLSEGEIVELNIPTGVPLVYEFDKNMRPLHHYYLGDATEIAARQ
EEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHH
SAVANQGKAG
HHHHCCCCCC
>Mature Secondary Structure 
AVTKLVLLRHGESEWNRENRFTGWTDVELSEKGRQEALAAGRLLKAQGFSFDIAYTSVL
CHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHH
KRAIHTLWHVLDKLDQPWLPVEKSWKLNERHYGALQGLNKAETAQQYGDEQVKLWRRAFA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHH
ITPPALTPDDPRYPGHDPRYAALSADELPLTESLATTIERVIPYWQQQIAPRISAGERII
CCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IAAHGNSLRALVKHLDHLSEGEIVELNIPTGVPLVYEFDKNMRPLHHYYLGDATEIAARQ
EEECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHCCCHHHHHHHH
SAVANQGKAG
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA