Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 238920728

GI number: 238920728

Start: 2732649

End: 2733665

Strand: Direct

Name: galE [H]

Synonym: NT01EI_2841

Alternate gene names: 238920728

Gene position: 2732649-2733665 (Clockwise)

Preceding gene: 238920727

Following gene: 238920729

Centisome position: 71.68

GC content: 63.13

Gene sequence:

>1017_bases
ATGATTGTATTAGTCACCGGAGGAAGCGGTTACATTGGCAGCCATACCTGCGTTCAGCTGCTGCAAGCGGGCCATACGCC
GGTCATCCTCGATAATCAGTGCAACAGCAAGGCCAGCGTGCTGGATCGTATCGCCACCCTGACCGGCACACGCCCGCGGC
TGTATCAGGGGGATGTTCGCGATCGGGCGCTGCTCAAGCGCATCTTTGCCGAGCAGGCCATCGACGCCGTGATCCACTTT
GCCGGCCTGAAGGCCGTCGGCGAATCGGTGCAGCAGCCGCTGGCCTACTACGACAATAACGTCGGCGGTACGCTGATCCT
GCTGGAGGCCATGGGCGACGCCGGGGTGCATAACATCATCTTCAGCTCTTCCGCCACCGTCTATGGCGAGCAGCCCCAGA
TACCCTATGTCGAAACCATGCCCACCGGCATGCCCGCCAGTCCCTATGGCCGCAGCAAGCTGATGGTGGAGCAAATCCTA
CAGGATCTGCAGCGTGCGGCGCCGCAGTGGAGCGTTACCCTGCTGCGCTACTTCAATCCGGTCGGCGCCCACCCCTCCGG
CCTGATGGGCGAGGATCCGCAGGGGATCCCCAACAACCTGATGCCCTATATCTCCCAGGTAGCCATCGGCCGCCGCGACG
CCCTGACTATTTTCGGCAACGACTATCCAACGCCCGACGGCACCGGCGTACGCGATTACATTCACGTGATGGATCTGGCC
GATGGCCATCTGGCGGCACTACAGGCCAAGACCCAACGGCCCGGCGTGCACATCTACAACCTCGGCGCCGGGGTTGGCTA
CAGCGTTCTACAGGTGGTGGACGCCTTCAGCCGCGCCTGTGGTAAGGTGCTGCCCTACCGCTTTGCCCCGCGCAGAGAGG
GCGATCTACCCGCCTACTGGGCCGACGCCGTCAAGGCCGATCGCGAGCTGAACTGGCGGGTCAGCCACACGCTACAGGCG
ATGGTCGAGGACACCTGGCGCTGGCAGTCACAGAACCCCACCGGTTACCCACAGTAA

Upstream 100 bases:

>100_bases
CTATCCAATGTAAACGATTCCATTTTTACCGTGCGGATCACCTTTTTAAGCCCATGAGCATGCTATCTTTCTATTATTGG
CATCGCATTGGGAGTCCAAC

Downstream 100 bases:

>100_bases
GGAGCGTAGCGATGAGCATTCCCTTTAATCCGGTGGATCACCCGCACCGCCGCTACAACCCCCTCAGCGATCAGTGGGTG
CTGGTGTCACCGCACCGCGC

Product: UDP-galactose-4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIVLVTGGSGYIGSHTCVQLLQAGHTPVILDNQCNSKASVLDRIATLTGTRPRLYQGDVRDRALLKRIFAEQAIDAVIHF
AGLKAVGESVQQPLAYYDNNVGGTLILLEAMGDAGVHNIIFSSSATVYGEQPQIPYVETMPTGMPASPYGRSKLMVEQIL
QDLQRAAPQWSVTLLRYFNPVGAHPSGLMGEDPQGIPNNLMPYISQVAIGRRDALTIFGNDYPTPDGTGVRDYIHVMDLA
DGHLAALQAKTQRPGVHIYNLGAGVGYSVLQVVDAFSRACGKVLPYRFAPRREGDLPAYWADAVKADRELNWRVSHTLQA
MVEDTWRWQSQNPTGYPQ

Sequences:

>Translated_338_residues
MIVLVTGGSGYIGSHTCVQLLQAGHTPVILDNQCNSKASVLDRIATLTGTRPRLYQGDVRDRALLKRIFAEQAIDAVIHF
AGLKAVGESVQQPLAYYDNNVGGTLILLEAMGDAGVHNIIFSSSATVYGEQPQIPYVETMPTGMPASPYGRSKLMVEQIL
QDLQRAAPQWSVTLLRYFNPVGAHPSGLMGEDPQGIPNNLMPYISQVAIGRRDALTIFGNDYPTPDGTGVRDYIHVMDLA
DGHLAALQAKTQRPGVHIYNLGAGVGYSVLQVVDAFSRACGKVLPYRFAPRREGDLPAYWADAVKADRELNWRVSHTLQA
MVEDTWRWQSQNPTGYPQ
>Mature_338_residues
MIVLVTGGSGYIGSHTCVQLLQAGHTPVILDNQCNSKASVLDRIATLTGTRPRLYQGDVRDRALLKRIFAEQAIDAVIHF
AGLKAVGESVQQPLAYYDNNVGGTLILLEAMGDAGVHNIIFSSSATVYGEQPQIPYVETMPTGMPASPYGRSKLMVEQIL
QDLQRAAPQWSVTLLRYFNPVGAHPSGLMGEDPQGIPNNLMPYISQVAIGRRDALTIFGNDYPTPDGTGVRDYIHVMDLA
DGHLAALQAKTQRPGVHIYNLGAGVGYSVLQVVDAFSRACGKVLPYRFAPRREGDLPAYWADAVKADRELNWRVSHTLQA
MVEDTWRWQSQNPTGYPQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=56.1764705882353, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=56.1764705882353, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=56.1764705882353, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI7657641, Length=272, Percent_Identity=28.6764705882353, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=74.1839762611276, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI48994969, Length=361, Percent_Identity=25.7617728531856, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788353, Length=360, Percent_Identity=25.8333333333333, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788366, Length=361, Percent_Identity=24.6537396121884, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=49.2753623188406, Blast_Score=342, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=48.9913544668588, Blast_Score=341, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=50.5813953488372, Blast_Score=342, Evalue=4e-95,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=53.2163742690059, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36975; Mature: 36975

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLVTGGSGYIGSHTCVQLLQAGHTPVILDNQCNSKASVLDRIATLTGTRPRLYQGDVR
CEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
DRALLKRIFAEQAIDAVIHFAGLKAVGESVQQPLAYYDNNVGGTLILLEAMGDAGVHNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHEE
FSSSATVYGEQPQIPYVETMPTGMPASPYGRSKLMVEQILQDLQRAAPQWSVTLLRYFNP
ECCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
VGAHPSGLMGEDPQGIPNNLMPYISQVAIGRRDALTIFGNDYPTPDGTGVRDYIHVMDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
DGHLAALQAKTQRPGVHIYNLGAGVGYSVLQVVDAFSRACGKVLPYRFAPRREGDLPAYW
CCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ADAVKADRELNWRVSHTLQAMVEDTWRWQSQNPTGYPQ
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIVLVTGGSGYIGSHTCVQLLQAGHTPVILDNQCNSKASVLDRIATLTGTRPRLYQGDVR
CEEEEECCCCCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
DRALLKRIFAEQAIDAVIHFAGLKAVGESVQQPLAYYDNNVGGTLILLEAMGDAGVHNII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHEE
FSSSATVYGEQPQIPYVETMPTGMPASPYGRSKLMVEQILQDLQRAAPQWSVTLLRYFNP
ECCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
VGAHPSGLMGEDPQGIPNNLMPYISQVAIGRRDALTIFGNDYPTPDGTGVRDYIHVMDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
DGHLAALQAKTQRPGVHIYNLGAGVGYSVLQVVDAFSRACGKVLPYRFAPRREGDLPAYW
CCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ADAVKADRELNWRVSHTLQAMVEDTWRWQSQNPTGYPQ
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]