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The map label for this gene is ydeN [H]

Identifier: 238920694

GI number: 238920694

Start: 2698078

End: 2699697

Strand: Reverse

Name: ydeN [H]

Synonym: NT01EI_2807

Alternate gene names: 238920694

Gene position: 2699697-2698078 (Counterclockwise)

Preceding gene: 238920695

Following gene: 238920693

Centisome position: 70.82

GC content: 60.56

Gene sequence:

>1620_bases
ATGACATTTTTCAGTAGTAAGAAAAAGCAGTTGGCAGGACTGGTGGCCGCTGCCTGTCTGTGCGGTGCCTCGTCAGCGTC
GGCGGCGCCGGCAGCCGCGACCGATAGCCGCCCCAATGTCCTGCTGGTGATTATGGACGATCTGGGCACCGGGCAGCTGG
ACTTTGCGCTGGATGCGCTGGATACCAAGGCGCTGGGCAAACGCCCGGTGGCTGAGCGCTACCAGGGCGATCTGGACAAG
ATGATCGATGCGGCGCGCCGGGCGATGCCCAACGTGGCCCAGCTGGCGAACCAGGGCGTGAAAATGACCAACGCCTTTGT
CGCCCATCCGGTGTGCGGGCCGTCGCGCGCCGGCATCTTCACCGGGCGCTATCCGGCCAGCTTTGGCACCTACAGCAACG
ACGATGCCATGCTCGGCGTTCCGCTGGACATCACGCTGCTGCCGGCACTGTTCCAGGAAAACGGCTACGCCACCGCCAAT
ATCGGCAAGTGGCACAACGCCCGTATCGATAAGAAGAACTTTGTCGATAAGGCCGATCAGACCCGTGACTATCACGACAA
TATGATCTCCGTCAGCGAGCCGGGCTATGGTCCGGAGTCGCGTGGTTTCGATTACTCCTACAGCTACTACGCCTCCGGTG
CGGCGCTGTGGAACTCGCCTGCGATTTGGCAGAATGGCAAGAATGTTGCTGCGCCGGGCTACCTGACCCACAACCTGACT
AACGAGACGTTGAAGTTTCTCGACGATCATCAGGGCAAGCCGTTCTTTATCAGCCTGGCCTACAGCGTTCCCCATATTCC
GCTGGAGCAGGCCTCCCCGGCTCGCTATATGGATAAATTCCATACCGGCAACGCCGAGGCGGATAAGTATTTCGCCGCCG
TTAATGCCGCTGACGAGGGCATTGGGCAGATTATCGAACGTCTGAAGGCGTTGGGTGAGCTGGATAACACCTTGATCTTC
TTCATTTCTGATAACGGGGCGGTGCATGAGTCACCGATGCCGCTCAACGGCATGGATCGCGGCTTTAAGGGGCAGATGTT
CAACGGTGGTGTGCATGTGCCGTTCGTTGCCTACTGGCCGAAGCATATTCCGGCCGGAACCCAGAGTAACGTGATGGTCA
GCGCCATCGACATCCTGCCTACGGCGCTGAAAGCTGCCGGGATCACCATTCCCGACGCGATGAAGGTGGACGGACGCGAC
ATCCTGCCGCAGCTGAGTGGCAAGGCACAGACGTCGCCGCACCGCTACCTTTTCTGGGCGGGGCCGGGCGCCAAGCACTA
CAGCGAGGAGAATCAGCCGTTCTGGTTCGACTACTGGAAGTGGATCACCTATGAGGCGCCGATGCCGCCGAAGAACCCCA
ACCTGGAGAAGCTCTCCCCCTCCTCCTGGGCGGTACGCGACGGAGAGTGGACGCTCTACTTCTATGACGACGGCAGCAAT
CGGGTGCAGCTGTTCAACGATCGCCTCGACCCGGCGGAGTCCCAGGATCTGGCGGCCAAGTATCCGCAGCGGGTGGCCGA
GATGAAGGCAGCCTACCACGACTGGATCAAGACCAAGCCCAAGCCGGTCGCCTGGGGACAGGATCGCTACCATATTCTGG
AGCAGTCGGCCCGCAGCTGA

Upstream 100 bases:

>100_bases
TGTGCCCTCCATCCTGATTACGCGCTTCTGGCTTAGCGTTGACGCCGCGCACAGTTACGGGGCACGCCTTGGTTAAGTAT
GTATAACAACGGAGTTGGCA

Downstream 100 bases:

>100_bases
GGGGCCTGAGCGGGGCAGCGCCGTATGCGCTGCCATTTTTTTGACTTTTTCTGAGCGGAGGCATCTGCATGGCGCAGAAG
AAAATCGAGGGCGCACCGCG

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MTFFSSKKKQLAGLVAAACLCGASSASAAPAAATDSRPNVLLVIMDDLGTGQLDFALDALDTKALGKRPVAERYQGDLDK
MIDAARRAMPNVAQLANQGVKMTNAFVAHPVCGPSRAGIFTGRYPASFGTYSNDDAMLGVPLDITLLPALFQENGYATAN
IGKWHNARIDKKNFVDKADQTRDYHDNMISVSEPGYGPESRGFDYSYSYYASGAALWNSPAIWQNGKNVAAPGYLTHNLT
NETLKFLDDHQGKPFFISLAYSVPHIPLEQASPARYMDKFHTGNAEADKYFAAVNAADEGIGQIIERLKALGELDNTLIF
FISDNGAVHESPMPLNGMDRGFKGQMFNGGVHVPFVAYWPKHIPAGTQSNVMVSAIDILPTALKAAGITIPDAMKVDGRD
ILPQLSGKAQTSPHRYLFWAGPGAKHYSEENQPFWFDYWKWITYEAPMPPKNPNLEKLSPSSWAVRDGEWTLYFYDDGSN
RVQLFNDRLDPAESQDLAAKYPQRVAEMKAAYHDWIKTKPKPVAWGQDRYHILEQSARS

Sequences:

>Translated_539_residues
MTFFSSKKKQLAGLVAAACLCGASSASAAPAAATDSRPNVLLVIMDDLGTGQLDFALDALDTKALGKRPVAERYQGDLDK
MIDAARRAMPNVAQLANQGVKMTNAFVAHPVCGPSRAGIFTGRYPASFGTYSNDDAMLGVPLDITLLPALFQENGYATAN
IGKWHNARIDKKNFVDKADQTRDYHDNMISVSEPGYGPESRGFDYSYSYYASGAALWNSPAIWQNGKNVAAPGYLTHNLT
NETLKFLDDHQGKPFFISLAYSVPHIPLEQASPARYMDKFHTGNAEADKYFAAVNAADEGIGQIIERLKALGELDNTLIF
FISDNGAVHESPMPLNGMDRGFKGQMFNGGVHVPFVAYWPKHIPAGTQSNVMVSAIDILPTALKAAGITIPDAMKVDGRD
ILPQLSGKAQTSPHRYLFWAGPGAKHYSEENQPFWFDYWKWITYEAPMPPKNPNLEKLSPSSWAVRDGEWTLYFYDDGSN
RVQLFNDRLDPAESQDLAAKYPQRVAEMKAAYHDWIKTKPKPVAWGQDRYHILEQSARS
>Mature_538_residues
TFFSSKKKQLAGLVAAACLCGASSASAAPAAATDSRPNVLLVIMDDLGTGQLDFALDALDTKALGKRPVAERYQGDLDKM
IDAARRAMPNVAQLANQGVKMTNAFVAHPVCGPSRAGIFTGRYPASFGTYSNDDAMLGVPLDITLLPALFQENGYATANI
GKWHNARIDKKNFVDKADQTRDYHDNMISVSEPGYGPESRGFDYSYSYYASGAALWNSPAIWQNGKNVAAPGYLTHNLTN
ETLKFLDDHQGKPFFISLAYSVPHIPLEQASPARYMDKFHTGNAEADKYFAAVNAADEGIGQIIERLKALGELDNTLIFF
ISDNGAVHESPMPLNGMDRGFKGQMFNGGVHVPFVAYWPKHIPAGTQSNVMVSAIDILPTALKAAGITIPDAMKVDGRDI
LPQLSGKAQTSPHRYLFWAGPGAKHYSEENQPFWFDYWKWITYEAPMPPKNPNLEKLSPSSWAVRDGEWTLYFYDDGSNR
VQLFNDRLDPAESQDLAAKYPQRVAEMKAAYHDWIKTKPKPVAWGQDRYHILEQSARS

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=432, Percent_Identity=29.1666666666667, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI59797060, Length=483, Percent_Identity=28.5714285714286, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI109389362, Length=514, Percent_Identity=25.6809338521401, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI71852584, Length=496, Percent_Identity=25.2016129032258, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI146229331, Length=407, Percent_Identity=26.2899262899263, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI146229329, Length=407, Percent_Identity=26.2899262899263, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI6005990, Length=407, Percent_Identity=26.2899262899263, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI146229324, Length=407, Percent_Identity=26.2899262899263, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI45430057, Length=422, Percent_Identity=25.8293838862559, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI53831991, Length=191, Percent_Identity=35.0785340314136, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI38569405, Length=355, Percent_Identity=27.0422535211268, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI38569407, Length=355, Percent_Identity=27.0422535211268, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4557659, Length=456, Percent_Identity=23.6842105263158, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI31742482, Length=197, Percent_Identity=27.9187817258883, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI157266309, Length=209, Percent_Identity=31.1004784688995, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI146229327, Length=303, Percent_Identity=26.0726072607261, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI5360208, Length=362, Percent_Identity=24.8618784530387, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI58743319, Length=182, Percent_Identity=29.6703296703297, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87081924, Length=507, Percent_Identity=40.8284023668639, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1790233, Length=399, Percent_Identity=27.0676691729323, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115533416, Length=520, Percent_Identity=24.2307692307692, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115533418, Length=467, Percent_Identity=24.6252676659529, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559078, Length=309, Percent_Identity=23.6245954692557, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24666109, Length=411, Percent_Identity=28.2238442822384, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281366397, Length=427, Percent_Identity=26.9320843091335, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281366395, Length=427, Percent_Identity=26.9320843091335, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666163, Length=427, Percent_Identity=26.9320843091335, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666175, Length=411, Percent_Identity=26.2773722627737, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281363223, Length=389, Percent_Identity=26.7352185089974, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24647401, Length=423, Percent_Identity=23.6406619385343, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 59434; Mature: 59303

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFFSSKKKQLAGLVAAACLCGASSASAAPAAATDSRPNVLLVIMDDLGTGQLDFALDAL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHH
DTKALGKRPVAERYQGDLDKMIDAARRAMPNVAQLANQGVKMTNAFVAHPVCGPSRAGIF
HHHHHCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCEEHHHEEECCCCCCCCCCEE
TGRYPASFGTYSNDDAMLGVPLDITLLPALFQENGYATANIGKWHNARIDKKNFVDKADQ
ECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
TRDYHDNMISVSEPGYGPESRGFDYSYSYYASGAALWNSPAIWQNGKNVAAPGYLTHNLT
CCCHHCCEEEECCCCCCCCCCCCCCEEHEEECCHHHCCCCCCEECCCCCCCCCCEECCCC
NETLKFLDDHQGKPFFISLAYSVPHIPLEQASPARYMDKFHTGNAEADKYFAAVNAADEG
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECHHHHH
IGQIIERLKALGELDNTLIFFISDNGAVHESPMPLNGMDRGFKGQMFNGGVHVPFVAYWP
HHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCEECCCCCCCEEEECC
KHIPAGTQSNVMVSAIDILPTALKAAGITIPDAMKVDGRDILPQLSGKAQTSPHRYLFWA
CCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEC
GPGAKHYSEENQPFWFDYWKWITYEAPMPPKNPNLEKLSPSSWAVRDGEWTLYFYDDGSN
CCCCHHCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEECCCC
RVQLFNDRLDPAESQDLAAKYPQRVAEMKAAYHDWIKTKPKPVAWGQDRYHILEQSARS
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TFFSSKKKQLAGLVAAACLCGASSASAAPAAATDSRPNVLLVIMDDLGTGQLDFALDAL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHH
DTKALGKRPVAERYQGDLDKMIDAARRAMPNVAQLANQGVKMTNAFVAHPVCGPSRAGIF
HHHHHCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCEEHHHEEECCCCCCCCCCEE
TGRYPASFGTYSNDDAMLGVPLDITLLPALFQENGYATANIGKWHNARIDKKNFVDKADQ
ECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
TRDYHDNMISVSEPGYGPESRGFDYSYSYYASGAALWNSPAIWQNGKNVAAPGYLTHNLT
CCCHHCCEEEECCCCCCCCCCCCCCEEHEEECCHHHCCCCCCEECCCCCCCCCCEECCCC
NETLKFLDDHQGKPFFISLAYSVPHIPLEQASPARYMDKFHTGNAEADKYFAAVNAADEG
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECHHHHH
IGQIIERLKALGELDNTLIFFISDNGAVHESPMPLNGMDRGFKGQMFNGGVHVPFVAYWP
HHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCEECCCCCCCEEEECC
KHIPAGTQSNVMVSAIDILPTALKAAGITIPDAMKVDGRDILPQLSGKAQTSPHRYLFWA
CCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEEC
GPGAKHYSEENQPFWFDYWKWITYEAPMPPKNPNLEKLSPSSWAVRDGEWTLYFYDDGSN
CCCCHHCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEECCCC
RVQLFNDRLDPAESQDLAAKYPQRVAEMKAAYHDWIKTKPKPVAWGQDRYHILEQSARS
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]