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The map label for this gene is mdtN [H]

Identifier: 238920660

GI number: 238920660

Start: 2669104

End: 2670093

Strand: Direct

Name: mdtN [H]

Synonym: NT01EI_2772

Alternate gene names: 238920660

Gene position: 2669104-2670093 (Clockwise)

Preceding gene: 238920659

Following gene: 238920661

Centisome position: 70.01

GC content: 56.87

Gene sequence:

>990_bases
ATGTTAAAGTCACCCGCTTCACGCACGGCGCTATTTCTCGCCATTACCTTCTCGATCATTATCTTTGGCATCCACAAGTA
CAACCAGCAACTGAGTACCCGCCATGGCGTTGTGCGGGCGAATATCATCGATATCGCGCCTCAGGTGAGCGGTCTGGTTA
CTCAGGTCAATGTGCGCCACAATCAGTCAGTCAAAAAGGGGGAGCTGCTTTTTTCCATCGACGACAGCGACTACAAGATC
AGCGTCCAGAAGGCCCAGGCGAATCTGGCTAACGTCGAACAACAGCTGTTAGAGCAGAGCGCGGCGGTTCTCTCGGCCAA
GGCGGCGCTGCAAAACGCGCAGAGCCAATGCAGCTATATGCAGGCAAACTTCCAGCGCATCAGTAACCTGAAGCAACGTG
ATTTTGCCTCGACCAATGATTACCAGCAGGCCGGGACGGATCTCAGCGTGAGCAAGGGAAATGTGGCCACTGCGCAGGCA
CGTCTGCAGCAGGCAATCGCCGCACGCGGTGCCATCGGCCCGGACAACGCCCAGCTGCTGACCGCCAGGGCAGCCTTGGC
CAAGGCCGAGCTGGATCTCTCCCGTACCCGGGTCTATGCGCCCAGCAACGGCAACATCGCCACGGTCAACCTGAACGCAG
GCGACTACGCTCGTCCCGGCAGCGCGGTTCTGGCTGAGGTCGATACCGATAATGTCTGGGTTGAGGGCGCCTTCCCGGAA
ACCGTCATCACCGGCATTCGCGTCGGCGATAAGGCCAGGATCTACCTGATGGCCGATACCAACACCGTCTACCACGGCCA
TGTACAAAGCATCGGCTCGGCGATCAACTCCAAAGAGTTGCCAAATCCGGGCTTACTTTCTGAACTGCCGCAAGTCTTTG
ACTGGGTTCGCCTGGCGGAAAACGTTCCGGTCAATATTCAATTGGATCCCGGTACCAATATGGAGAATCTCATTCCGGGA
CTCAGCGCGACCGTCAATATCATTAAGTAA

Upstream 100 bases:

>100_bases
TAAGCTATTTCTGGCATCCACGTCTGATCGTCTGGGCTTATGCATCAGCCATCTATGCATTACTGGTTATCGCCATCATT
TATATTTAACAGGTTATGAT

Downstream 100 bases:

>100_bases
GGCGCCCCATGCTACTGCAAAGTTTAAAAGCCCTGCGGCTCACCCTAGCCGTCATGCTCTCGCTCTATATTGCCATGCGA
CTGGGGATGCACTCGCCGGA

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MLKSPASRTALFLAITFSIIIFGIHKYNQQLSTRHGVVRANIIDIAPQVSGLVTQVNVRHNQSVKKGELLFSIDDSDYKI
SVQKAQANLANVEQQLLEQSAAVLSAKAALQNAQSQCSYMQANFQRISNLKQRDFASTNDYQQAGTDLSVSKGNVATAQA
RLQQAIAARGAIGPDNAQLLTARAALAKAELDLSRTRVYAPSNGNIATVNLNAGDYARPGSAVLAEVDTDNVWVEGAFPE
TVITGIRVGDKARIYLMADTNTVYHGHVQSIGSAINSKELPNPGLLSELPQVFDWVRLAENVPVNIQLDPGTNMENLIPG
LSATVNIIK

Sequences:

>Translated_329_residues
MLKSPASRTALFLAITFSIIIFGIHKYNQQLSTRHGVVRANIIDIAPQVSGLVTQVNVRHNQSVKKGELLFSIDDSDYKI
SVQKAQANLANVEQQLLEQSAAVLSAKAALQNAQSQCSYMQANFQRISNLKQRDFASTNDYQQAGTDLSVSKGNVATAQA
RLQQAIAARGAIGPDNAQLLTARAALAKAELDLSRTRVYAPSNGNIATVNLNAGDYARPGSAVLAEVDTDNVWVEGAFPE
TVITGIRVGDKARIYLMADTNTVYHGHVQSIGSAINSKELPNPGLLSELPQVFDWVRLAENVPVNIQLDPGTNMENLIPG
LSATVNIIK
>Mature_329_residues
MLKSPASRTALFLAITFSIIIFGIHKYNQQLSTRHGVVRANIIDIAPQVSGLVTQVNVRHNQSVKKGELLFSIDDSDYKI
SVQKAQANLANVEQQLLEQSAAVLSAKAALQNAQSQCSYMQANFQRISNLKQRDFASTNDYQQAGTDLSVSKGNVATAQA
RLQQAIAARGAIGPDNAQLLTARAALAKAELDLSRTRVYAPSNGNIATVNLNAGDYARPGSAVLAEVDTDNVWVEGAFPE
TVITGIRVGDKARIYLMADTNTVYHGHVQSIGSAINSKELPNPGLLSELPQVFDWVRLAENVPVNIQLDPGTNMENLIPG
LSATVNIIK

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=319, Percent_Identity=29.7805642633229, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87081951, Length=302, Percent_Identity=31.1258278145695, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789637, Length=324, Percent_Identity=30.5555555555556, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788711, Length=350, Percent_Identity=30, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790024, Length=296, Percent_Identity=27.027027027027, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790012, Length=295, Percent_Identity=24.7457627118644, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789041, Length=310, Percent_Identity=25.1612903225806, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081796, Length=288, Percent_Identity=22.9166666666667, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 35432; Mature: 35432

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSPASRTALFLAITFSIIIFGIHKYNQQLSTRHGVVRANIIDIAPQVSGLVTQVNVRH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHEECCCHHCCCEEEEEECC
NQSVKKGELLFSIDDSDYKISVQKAQANLANVEQQLLEQSAAVLSAKAALQNAQSQCSYM
CCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QANFQRISNLKQRDFASTNDYQQAGTDLSVSKGNVATAQARLQQAIAARGAIGPDNAQLL
HHHHHHHHHHHHHCCCCCCCHHHCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
TARAALAKAELDLSRTRVYAPSNGNIATVNLNAGDYARPGSAVLAEVDTDNVWVEGAFPE
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCH
TVITGIRVGDKARIYLMADTNTVYHGHVQSIGSAINSKELPNPGLLSELPQVFDWVRLAE
HHHHHEEECCCEEEEEEECCCEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
NVPVNIQLDPGTNMENLIPGLSATVNIIK
CCCEEEEECCCCCHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MLKSPASRTALFLAITFSIIIFGIHKYNQQLSTRHGVVRANIIDIAPQVSGLVTQVNVRH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHEECCCHHCCCEEEEEECC
NQSVKKGELLFSIDDSDYKISVQKAQANLANVEQQLLEQSAAVLSAKAALQNAQSQCSYM
CCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QANFQRISNLKQRDFASTNDYQQAGTDLSVSKGNVATAQARLQQAIAARGAIGPDNAQLL
HHHHHHHHHHHHHCCCCCCCHHHCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
TARAALAKAELDLSRTRVYAPSNGNIATVNLNAGDYARPGSAVLAEVDTDNVWVEGAFPE
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCH
TVITGIRVGDKARIYLMADTNTVYHGHVQSIGSAINSKELPNPGLLSELPQVFDWVRLAE
HHHHHEEECCCEEEEEEECCCEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
NVPVNIQLDPGTNMENLIPGLSATVNIIK
CCCEEEEECCCCCHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]