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The map label for this gene is moaC

Identifier: 238920527

GI number: 238920527

Start: 2532297

End: 2532782

Strand: Reverse

Name: moaC

Synonym: NT01EI_2639

Alternate gene names: 238920527

Gene position: 2532782-2532297 (Counterclockwise)

Preceding gene: 238920528

Following gene: 238920526

Centisome position: 66.44

GC content: 61.11

Gene sequence:

>486_bases
ATGAGCCAGTTAACCCATATTAATGCGGCCGGTGAGGCGCACATGGTTGACGTTTCCGCCAAGGCGGAGACGGTACGTGA
AGCGCGCGCCGAGGCCTATGTCACCATGCGTCAGGATACCCTGGCGATGATCATCGACGGTAAACACCCTAAGGGGGACG
TATTTGCCACCGCCCGTATTGCCGGTATCCAGGCCGCCAAGAGCACCTGGCAGCTAATCCCGCTATGTCACCCGCTGTTG
CTGAGCAAGGTCGAGGTGACGCTGAGCGTCGAGCCGGTCCACAGTCGGGTACGGATCGAAACCTGCTGCCGTCTGTGCGG
TAAGACCGGGGTGGAGATGGAGGCGCTGAGCGCCGCCTCGGTGGCCGCGTTGACCATCTATGACATGTGCAAAGCGGTGC
AGAAAGACATGGTGATCGGGCCGGTGCGTCTGCTGGCCAAAAGCGGCGGCAAGTCCGGGGATTTTCACGCGGGGGAGGTA
CAATGA

Upstream 100 bases:

>100_bases
GCCATTTCCTGCATCAGGGCGACAGTGGCCATACCCAGAATCTTTCTTTCATCGGCGGCTAGTCCGCCGGGTAGACCCAC
CTTTTATACAGCGAAGAATG

Downstream 100 bases:

>100_bases
TCCAGGTGCACTTTTTTGCTCAGGTGCGCGAGCTGACCGGCTGCGCCGAGTTGGCCTGTGAGCCCTGTCGGGATGTCGAG
ACGCTGCGCGCCACGCTGGC

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSQLTHINAAGEAHMVDVSAKAETVREARAEAYVTMRQDTLAMIIDGKHPKGDVFATARIAGIQAAKSTWQLIPLCHPLL
LSKVEVTLSVEPVHSRVRIETCCRLCGKTGVEMEALSAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFHAGEV
Q

Sequences:

>Translated_161_residues
MSQLTHINAAGEAHMVDVSAKAETVREARAEAYVTMRQDTLAMIIDGKHPKGDVFATARIAGIQAAKSTWQLIPLCHPLL
LSKVEVTLSVEPVHSRVRIETCCRLCGKTGVEMEALSAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFHAGEV
Q
>Mature_160_residues
SQLTHINAAGEAHMVDVSAKAETVREARAEAYVTMRQDTLAMIIDGKHPKGDVFATARIAGIQAAKSTWQLIPLCHPLLL
SKVEVTLSVEPVHSRVRIETCCRLCGKTGVEMEALSAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFHAGEVQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=89.6774193548387, Blast_Score=286, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=40.9395973154362, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574490, Length=160, Percent_Identity=54.375, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=54.421768707483, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_EDWI9 (C5B7H1)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934042.1
- GeneID:   7961665
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2639
- OMA:   PMCHPLM
- ProtClustDB:   CLSK2813388
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17227; Mature: 17096

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLTHINAAGEAHMVDVSAKAETVREARAEAYVTMRQDTLAMIIDGKHPKGDVFATARI
CCCCCEECCCCCEEEEECCHHHHHHHHHHHHHEEEECCCEEEEEEECCCCCCCEEEEHHH
AGIQAAKSTWQLIPLCHPLLLSKVEVTLSVEPVHSRVRIETCCRLCGKTGVEMEALSAAS
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFHAGEVQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQLTHINAAGEAHMVDVSAKAETVREARAEAYVTMRQDTLAMIIDGKHPKGDVFATARI
CCCCEECCCCCEEEEECCHHHHHHHHHHHHHEEEECCCEEEEEEECCCCCCCEEEEHHH
AGIQAAKSTWQLIPLCHPLLLSKVEVTLSVEPVHSRVRIETCCRLCGKTGVEMEALSAAS
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFHAGEVQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA