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The map label for this gene is grx [H]

Identifier: 238920418

GI number: 238920418

Start: 2428878

End: 2428997

Strand: Direct

Name: grx [H]

Synonym: NT01EI_2528

Alternate gene names: 238920418

Gene position: 2428878-2428997 (Clockwise)

Preceding gene: 238920413

Following gene: 238920420

Centisome position: 63.71

GC content: 51.67

Gene sequence:

>120_bases
GTGGGCAAACCGGTCGAAACCGTTCCGCAGGTGTTCATCGATCAGCAGCATATCGGCGGCTGCACCGATTTTGAGGCCTA
TGCCAAAACGCATCTGCAGCTGTTTGATAAGAGCAAATAA

Upstream 100 bases:

>100_bases
AAGAGTTGGCTGAAAAACTGGCCGCCGAGCGCGACGACTTCACTTTCGCTACGTCGATATCCACGCAGAGGGCATCAGTA
AAGAGGATCTCTCCAAGACT

Downstream 100 bases:

>100_bases
CGCCACCTGCACAGCAAAAAACCCGCCGCGGCGGGTTTTTTATTTTGGCGCAACGCTACCGTTAAAGCGATAGAGATTAA
TCGGTATAGACTATCTAACC

Product: glutaredoxin-1 (Grx1)

Products: deoxyribonucleotides [C]

Alternate protein names: NA

Number of amino acids: Translated: 39; Mature: 38

Protein sequence:

>39_residues
MGKPVETVPQVFIDQQHIGGCTDFEAYAKTHLQLFDKSK

Sequences:

>Translated_39_residues
MGKPVETVPQVFIDQQHIGGCTDFEAYAKTHLQLFDKSK
>Mature_38_residues
GKPVETVPQVFIDQQHIGGCTDFEAYAKTHLQLFDKSK

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011902
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 4408; Mature: 4277

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPVETVPQVFIDQQHIGGCTDFEAYAKTHLQLFDKSK
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GKPVETVPQVFIDQQHIGGCTDFEAYAKTHLQLFDKSK
CCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ribonucleotides [C]

Specific reaction: ribonucleotides = deoxyribonucleotides [C]

General reaction: deoxyribonucleotide biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]