Click here to switch to the map view.

The map label for this gene is csgD [H]

Identifier: 238920403

GI number: 238920403

Start: 2414245

End: 2414865

Strand: Reverse

Name: csgD [H]

Synonym: NT01EI_2513

Alternate gene names: 238920403

Gene position: 2414865-2414245 (Counterclockwise)

Preceding gene: 238920414

Following gene: 238920402

Centisome position: 63.34

GC content: 47.34

Gene sequence:

>621_bases
ATGGCGACCAGCCATAACATACTTAAGAAAAAAAACGGACTATCATTAATTACCTACCCCACGCTACAGTCGATGCTTTT
GGTCGATGTGCTTAATAATTACCTTGGTGTGCCAATTTGTCTGTGTGATGCAACCAGAAATTCAAATTATTTATTGGGTG
ACTGTAGTCTGATTATATTTGATACAATGTTACTTGATGGTGATCCGACGCAGCGAGCGTGTTGGCTTGAGGCTATATTT
AACCGGCGGGTAGGCCCGCGAATTATTTTGATCAACGTGGGTACCTATGATGAGGTGCTGGCGTGGTGCCAGCATGGGAA
TATCATTGCCGTTTTTCCAGCCAAGACGCATCAGCAGGCACTGATCCGCCGGCTACGAACCCTGTTGATGGCCGCGCAGG
AGGAGGGGCCGGGCTATATGACTCCCACGCCTCGCCTGACTCTGCGTGAACTGGAGGTACTGAAGGCGATGCAGCAGGGG
GCCAGTAATCTGGATATCTCGCGCATCCTGTATATCAGTAAAAATACGGTAAGAACGCATGTATATAATATTTTTAAGAA
AATATCAGTGAAAAATCGGATCCAGGCGGTGATATGGGCCGATACTCACCTGTGTGGATAG

Upstream 100 bases:

>100_bases
TATAATTAGAACACGTTATGATATTTCAATTGGTTATTAGTCAGTGCTTGGCCTTATCGTTAAAAATTAGCATCTGCGTT
TCCATGAAGAGGATTTCATG

Downstream 100 bases:

>100_bases
GGAGGGTATCAGCAGCGGGGCTGACGTCGTAGGCCACGGTGGGTAATATCTGCGGTGGAGAATACGCAAGGAGAAGCGAT
GAGGGTAAAAACGTCTGTCC

Product: csgAB operon transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MATSHNILKKKNGLSLITYPTLQSMLLVDVLNNYLGVPICLCDATRNSNYLLGDCSLIIFDTMLLDGDPTQRACWLEAIF
NRRVGPRIILINVGTYDEVLAWCQHGNIIAVFPAKTHQQALIRRLRTLLMAAQEEGPGYMTPTPRLTLRELEVLKAMQQG
ASNLDISRILYISKNTVRTHVYNIFKKISVKNRIQAVIWADTHLCG

Sequences:

>Translated_206_residues
MATSHNILKKKNGLSLITYPTLQSMLLVDVLNNYLGVPICLCDATRNSNYLLGDCSLIIFDTMLLDGDPTQRACWLEAIF
NRRVGPRIILINVGTYDEVLAWCQHGNIIAVFPAKTHQQALIRRLRTLLMAAQEEGPGYMTPTPRLTLRELEVLKAMQQG
ASNLDISRILYISKNTVRTHVYNIFKKISVKNRIQAVIWADTHLCG
>Mature_205_residues
ATSHNILKKKNGLSLITYPTLQSMLLVDVLNNYLGVPICLCDATRNSNYLLGDCSLIIFDTMLLDGDPTQRACWLEAIFN
RRVGPRIILINVGTYDEVLAWCQHGNIIAVFPAKTHQQALIRRLRTLLMAAQEEGPGYMTPTPRLTLRELEVLKAMQQGA
SNLDISRILYISKNTVRTHVYNIFKKISVKNRIQAVIWADTHLCG

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=208, Percent_Identity=31.7307692307692, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 23239; Mature: 23107

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSHNILKKKNGLSLITYPTLQSMLLVDVLNNYLGVPICLCDATRNSNYLLGDCSLIIF
CCCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECHHEEEH
DTMLLDGDPTQRACWLEAIFNRRVGPRIILINVGTYDEVLAWCQHGNIIAVFPAKTHQQA
HHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCHHHH
LIRRLRTLLMAAQEEGPGYMTPTPRLTLRELEVLKAMQQGASNLDISRILYISKNTVRTH
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHH
VYNIFKKISVKNRIQAVIWADTHLCG
HHHHHHHHHHHHHEEEEEEECCCCCC
>Mature Secondary Structure 
ATSHNILKKKNGLSLITYPTLQSMLLVDVLNNYLGVPICLCDATRNSNYLLGDCSLIIF
CCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECHHEEEH
DTMLLDGDPTQRACWLEAIFNRRVGPRIILINVGTYDEVLAWCQHGNIIAVFPAKTHQQA
HHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEEECCCCHHHH
LIRRLRTLLMAAQEEGPGYMTPTPRLTLRELEVLKAMQQGASNLDISRILYISKNTVRTH
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHH
VYNIFKKISVKNRIQAVIWADTHLCG
HHHHHHHHHHHHHEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]