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The map label for this gene is mukE [H]

Identifier: 238920328

GI number: 238920328

Start: 2329839

End: 2330591

Strand: Reverse

Name: mukE [H]

Synonym: NT01EI_2438

Alternate gene names: 238920328

Gene position: 2330591-2329839 (Counterclockwise)

Preceding gene: 238920329

Following gene: 238920327

Centisome position: 61.13

GC content: 60.56

Gene sequence:

>753_bases
ATGAGTACGGAGCCAAGGTGCAGGCCCATGTCATCGACAAATACTGAAAATACTATGCCGGCCAAGCTGGCACAGGCGGT
GTTTAATCCGCTGTTTCCCGCGCTGGACAGCCAGTTGCGCGCCGGGCGTCATATCGGCATCGACGATCTGGACAATCACG
CTTTCCTGATGGATTTTCAGGAGGAGCTGGAGCTGTTTTATGGGCGCTATAATGTCGAGCTGATCCGTGCGCCGGAGGGC
TTCTTCTATCTGCGTCCCCGCTCCACGACCCTGATCCCCCGCTCGGTGCTGTCTGAGCTGGACATGCTGGTGGGCAAGAT
CCTCTGTTATCTCTACCTCAGCCCGGAGCGGCTGGCCCATGAGGGGATCTTCAGTCAGCAGGAGCTGTATGACGAGCTGC
TGACCCTGACCGATGAGAGCAAGTTGCTCAGGCTGGTTAACCAGCGCTCGACCGGCTCTGATCTGGACCGTCAGAAGCTA
CAGGAGAAGCTGCGCACCTCGCTGAACCGCCTGCGCCGGCTGGGAATGGTGTTCTTTATCGGTAGCGACAGCGCCAGGTT
CCGCATTACCGAGGCGGTGTTCCGCTTCGGCGCCGACGTACGTGCCGGCGACGATGTGCGCGATGCCCAGATGCGCCTGA
TCCGCGATGGCGAGGCGGTCACGCTGGAGCCATCGCTGGCGCTCAATGACGGCGCGGCGGACGACGCGCAGGCGGAACAA
GAATCCGAGGATGCAGAGGATGAACAGGAATGA

Upstream 100 bases:

>100_bases
CGCCATTTTGACATGGCAAGAATTTTGGTTGACCAGGCGGTACGCCTGGGTGTAGCCGAAGCAGATTTTAACGGATTGCA
GGCCCAGTGGCAGGCGATCA

Downstream 100 bases:

>100_bases
TTGAACGCGGTAAGTTTCGCTCGCTGACCCTGGTTAACTGGAACGGCTTCTTTGCCCGGACCTTCGATTTGGACGAGCTG
GTGACCACCCTCTCCGGCGG

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSTEPRCRPMSSTNTENTMPAKLAQAVFNPLFPALDSQLRAGRHIGIDDLDNHAFLMDFQEELELFYGRYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMLVGKILCYLYLSPERLAHEGIFSQQELYDELLTLTDESKLLRLVNQRSTGSDLDRQKL
QEKLRTSLNRLRRLGMVFFIGSDSARFRITEAVFRFGADVRAGDDVRDAQMRLIRDGEAVTLEPSLALNDGAADDAQAEQ
ESEDAEDEQE

Sequences:

>Translated_250_residues
MSTEPRCRPMSSTNTENTMPAKLAQAVFNPLFPALDSQLRAGRHIGIDDLDNHAFLMDFQEELELFYGRYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMLVGKILCYLYLSPERLAHEGIFSQQELYDELLTLTDESKLLRLVNQRSTGSDLDRQKL
QEKLRTSLNRLRRLGMVFFIGSDSARFRITEAVFRFGADVRAGDDVRDAQMRLIRDGEAVTLEPSLALNDGAADDAQAEQ
ESEDAEDEQE
>Mature_249_residues
STEPRCRPMSSTNTENTMPAKLAQAVFNPLFPALDSQLRAGRHIGIDDLDNHAFLMDFQEELELFYGRYNVELIRAPEGF
FYLRPRSTTLIPRSVLSELDMLVGKILCYLYLSPERLAHEGIFSQQELYDELLTLTDESKLLRLVNQRSTGSDLDRQKLQ
EKLRTSLNRLRRLGMVFFIGSDSARFRITEAVFRFGADVRAGDDVRDAQMRLIRDGEAVTLEPSLALNDGAADDAQAEQE
SEDAEDEQE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=234, Percent_Identity=79.0598290598291, Blast_Score=379, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 28471; Mature: 28340

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEPRCRPMSSTNTENTMPAKLAQAVFNPLFPALDSQLRAGRHIGIDDLDNHAFLMDFQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHH
EELELFYGRYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMLVGKILCYLYLSPERLAH
HHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EGIFSQQELYDELLTLTDESKLLRLVNQRSTGSDLDRQKLQEKLRTSLNRLRRLGMVFFI
HCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
GSDSARFRITEAVFRFGADVRAGDDVRDAQMRLIRDGEAVTLEPSLALNDGAADDAQAEQ
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHH
ESEDAEDEQE
HHHCCCCCCC
>Mature Secondary Structure 
STEPRCRPMSSTNTENTMPAKLAQAVFNPLFPALDSQLRAGRHIGIDDLDNHAFLMDFQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHH
EELELFYGRYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMLVGKILCYLYLSPERLAH
HHHHHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EGIFSQQELYDELLTLTDESKLLRLVNQRSTGSDLDRQKLQEKLRTSLNRLRRLGMVFFI
HCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
GSDSARFRITEAVFRFGADVRAGDDVRDAQMRLIRDGEAVTLEPSLALNDGAADDAQAEQ
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHH
ESEDAEDEQE
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]