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The map label for this gene is ptsG [H]

Identifier: 238920252

GI number: 238920252

Start: 2262849

End: 2264282

Strand: Reverse

Name: ptsG [H]

Synonym: NT01EI_2361

Alternate gene names: 238920252

Gene position: 2264282-2262849 (Counterclockwise)

Preceding gene: 238920253

Following gene: 238920250

Centisome position: 59.39

GC content: 58.58

Gene sequence:

>1434_bases
ATGTTTAAAAACGCATTTGCCAACCTGCAAAAGGTTGGTAAGTCACTGATGCTGCCCGTATCAGTCCTACCTATCGCAGG
CATACTGCTCGGCGTCGGATCGGCAAACTTTAGTTGGCTTCCCGCGGTGGTTTCCCATGTGATGGCTGAGGCCGGTGGCT
CGGTATTTGCCAATATGCCGCTGATCTTTGCCATCGGCGTGGCGTTGGGATTTACCAATAATGACGGGGTATCAGCCCTG
GCCGCCGTGGTTGCCTATGGCATCATGGTGAAAACCATGGCCGTGGTGGCACCGCTGGTGCTGCATCTGCCCTCGGAAGA
GATTGCCGCCAAGCATCTGGCGGATACCGGGGTGCTCGGCGGGATCATCGCCGGTTCTATCGCCGCCTATATGTTTAACC
GCTTCTACCGCATCAAACTGCCGGAATATCTGGGCTTCTTTGCCGGTAAACGCTTTGTGCCGATTATCTCCGGCCTGGCA
GCGATTGCGCTGGGCGTGGTGCTCTCCTTCATTTGGCCGCCGGTTGGCTCCGCCATTCAGCATTTTTCCCAGTGGGCCGC
CTATCAGAACCCGGTGGTCGCATTCGGCATCTATGGTCTGGTAGAGCGTGCACTGGTGCCATTTGGCCTGCACCATATCT
GGAACGTACCGTTCCAGATGCAGATCGGTGAGTATGTGAATGCGGCGGGACAGGTGTTCCACGGCGATATTCCGCGCTAT
ATGGCCGGCGATCCGACGGCGGGTAAACTCTCCGGTGGCTTCCTGTTCAAAATGTATGGCCTGCCGGCGGCGGCGATCGC
CATCTGGCATTCGGCGAAGCCGGAAAACCGTACCAAGGTGGCCGGGATCATGATCTCCGCGGCGCTGACCTCATTCCTGA
CCGGGATCACCGAGCCTATCGAGTTTGCCTTTATGTTCGTGGCGCCGATCCTGTATGTGATCCACGCGATTCTGGCCGGT
CTGGCGTTCCCGATCTGTATCCTGCTGGGGATGCGCGACGGAACCAGCTTCTCACATGGCCTGATCGATTTTATCGTTCT
GAGCGGCAACGGCAGCAAGCTGTGGCTGTTCCCGATCGTCGGCCTGTGCTACGCGCTGCTGTACTACGTGATCTTCCGCG
TGCTGATCGTCAAGCTGAACCTGAAGACGCCGGGCCGCGAGGAGAGCAGCAGCGAGCAGAGCGCGCAGAGCGGCAACGAC
ATGGCTGCGTCGCTGGTACAGGCATTTGGCGGTAAGGAAAATATTACCAACCTGGACGCCTGTATTACCCGCCTGCGCGT
CAGCGTCGCCGATGTCGCCAGGGTGGATCAGGCCGGGCTTAAGAAGCTGGGCGCTGCCGGGGTGGTGGTGGCGGGCTCTG
GGGTGCAGGCCATCTTTGGTACCAAGTCCGATAACCTGAAGACCGAAATGGACGACTATATTCGCAGCCATTGA

Upstream 100 bases:

>100_bases
GGTGCATAGACACCCGACGTCCGGGGCTCTCTTCCCTGCGGCGGTGCGCTGTTTCCGGCGCGGATAAAAAGAGCATTTTT
ACTCAGGAGCACACTCAATT

Downstream 100 bases:

>100_bases
TGCAAGTGCGTGATACGCCTTTGACAGGGTGGTTACGTTAGTTCGCCCCCGTTTTTACGGGGGTTAATGAGATGGTCACC
CCCCCACCCTGTGAGCGGTA

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVVSHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSAL
AAVVAYGIMVKTMAVVAPLVLHLPSEEIAAKHLADTGVLGGIIAGSIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
AIALGVVLSFIWPPVGSAIQHFSQWAAYQNPVVAFGIYGLVERALVPFGLHHIWNVPFQMQIGEYVNAAGQVFHGDIPRY
MAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPENRTKVAGIMISAALTSFLTGITEPIEFAFMFVAPILYVIHAILAG
LAFPICILLGMRDGTSFSHGLIDFIVLSGNGSKLWLFPIVGLCYALLYYVIFRVLIVKLNLKTPGREESSSEQSAQSGND
MAASLVQAFGGKENITNLDACITRLRVSVADVARVDQAGLKKLGAAGVVVAGSGVQAIFGTKSDNLKTEMDDYIRSH

Sequences:

>Translated_477_residues
MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVVSHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSAL
AAVVAYGIMVKTMAVVAPLVLHLPSEEIAAKHLADTGVLGGIIAGSIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
AIALGVVLSFIWPPVGSAIQHFSQWAAYQNPVVAFGIYGLVERALVPFGLHHIWNVPFQMQIGEYVNAAGQVFHGDIPRY
MAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPENRTKVAGIMISAALTSFLTGITEPIEFAFMFVAPILYVIHAILAG
LAFPICILLGMRDGTSFSHGLIDFIVLSGNGSKLWLFPIVGLCYALLYYVIFRVLIVKLNLKTPGREESSSEQSAQSGND
MAASLVQAFGGKENITNLDACITRLRVSVADVARVDQAGLKKLGAAGVVVAGSGVQAIFGTKSDNLKTEMDDYIRSH
>Mature_477_residues
MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVVSHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSAL
AAVVAYGIMVKTMAVVAPLVLHLPSEEIAAKHLADTGVLGGIIAGSIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
AIALGVVLSFIWPPVGSAIQHFSQWAAYQNPVVAFGIYGLVERALVPFGLHHIWNVPFQMQIGEYVNAAGQVFHGDIPRY
MAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPENRTKVAGIMISAALTSFLTGITEPIEFAFMFVAPILYVIHAILAG
LAFPICILLGMRDGTSFSHGLIDFIVLSGNGSKLWLFPIVGLCYALLYYVIFRVLIVKLNLKTPGREESSSEQSAQSGND
MAASLVQAFGGKENITNLDACITRLRVSVADVARVDQAGLKKLGAAGVVVAGSGVQAIFGTKSDNLKTEMDDYIRSH

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=477, Percent_Identity=90.7756813417191, Blast_Score=882, Evalue=0.0,
Organism=Escherichia coli, GI1786894, Length=485, Percent_Identity=39.5876288659794, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1787908, Length=514, Percent_Identity=36.9649805447471, Blast_Score=271, Evalue=9e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50670; Mature: 50670

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]