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The map label for this gene is ydeL [H]

Identifier: 238920234

GI number: 238920234

Start: 2240183

End: 2241640

Strand: Direct

Name: ydeL [H]

Synonym: NT01EI_2343

Alternate gene names: 238920234

Gene position: 2240183-2241640 (Clockwise)

Preceding gene: 238920233

Following gene: 238920236

Centisome position: 58.76

GC content: 62.21

Gene sequence:

>1458_bases
ATGCTGTCGTTTACTTTGGACCGTAACAGCCCACTTTCGCTGCAAAAACAAATCTACCAACAGTTTCATACCGCCCTGCA
CGATGGCTCGCTGCAGTGCGGTGAACGCCTGCCCTCGATCCGCGAGCTGGGCAGCAAGCTGCAGGTCTCACGCAATACCA
TTACCGCCGTCTATGAGAAGCTGCTGCAGGAGGGGTTCATCGCCAGCCGCCCCGGCGTCGGCTATAACGTCGTGCAGGCC
AGCCATATTGATCTACCCGAGAGCCCGGCGGCGCAGCAAGAGCTGGATCATCCGCCCAGCGTGCTGTGTACTCAGGCGCC
AGAAACCTACGTCGACGTCAACAGTCCGCTGTTCTTCAGCCTGGGCAATCCCGATGAGTCGGCCTTTCCCTGGCAGCGCT
GGCGTAGCTGGAACAACAAGGCATCGCGCAGCAAGCACCTGCTGATGACCCGCTATCATCCTCCGGCCGGGCTGCTGTCA
CTGCGCCAGGAGCTGGTTAAATACCTGGCTGGCGCCCGCGGCTTCCATACCGATCCGCAGCACATCATCATCACCAACGG
CGTGCAGGAGGGACTGGCGCTGCTGGCCCGCACCCTGCTGACACCGCAGGAGCACATCGCCGTCGAATCACCGTGCTATT
CCGGCGCCTGGAACCTATTCAACAGTTTCGCCCCCCATATTCACGCCATACCGGTCGATGACGGCGGTCTGCGTACCGAT
CTGCTGCCTGAGCAGCAGTGCGCGCTGGCCTATGTGACCCCCTCTCATCAATACCCGGTGGGCAGCACCCTGCCACTGGC
GCGCCGCCTGGCCCTGCTCGAGTGGTCGCGCCGTTCCAACGCCTACGTGATCGAAGATGACTACGACACCACCTTCCTCT
ACGGGACGCAGCCGCTGCCGGCGCTAAAGTCACTGGAGGATGCCAACAACGTGATCTACCTGAGCAGCTTCTCCAAAACT
CTGGGGCCGGGCATGCGGCTCGGCTTTATGGTTTGCCCGGATCGACTGGTGGAGCCGATCCTGAATCTGAAGGCGCTGTG
GAACCACGGCGCCAGCTGGCTATATCAACAGTTCCTGGCCGATTTTATGCAGGATCAGGGCTACCACCGCCACCTGCGCA
AGCTGGAGCTGGAGTATGCCGCGCGGCAGAAGCTGCTGCGCGAAGGGCTGAGCGCCCTGTTTCCGCGCGCGCGCCTGTTG
GGCACCTCATCGGGACTGCACCTGACCCTGAAGACCGATCTCCCGGCGCAGCGGGTTAACCAGCTGCGCGAACGCTGCCT
GCGCGACGGCGTGCGCTTCGATACGCTGCAAAGCATGTGCAATGGCTCGGAGTGCGCCTACATGGCGCACAACGGTGCAC
CGCTGATGCTGTTTGGATTTAGCGCCCTGTCTGAAGTGAAGATCCGGCGGGCGCTGGCGATCATCGCCAGCGCAGCCAAA
GAGCTGGGGCTGGCCTAA

Upstream 100 bases:

>100_bases
CCACACAATTTATGTGAACAGCCGCGCATGCCGCGTGCACATCGCCATCCGCTGTGATAATAGTGGAACCATCAGGTCAT
TGATCCCGTTTGGAACAGGC

Downstream 100 bases:

>100_bases
ACGCTACGTTAGGCGTGGGGTGGCTCATCGGCCGGCAGCTGCAGGCGGAACACCTGCTGCAGGACGCCGGGCGCGTCGCT
GTTCAACAGCTGCTGATAAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MLSFTLDRNSPLSLQKQIYQQFHTALHDGSLQCGERLPSIRELGSKLQVSRNTITAVYEKLLQEGFIASRPGVGYNVVQA
SHIDLPESPAAQQELDHPPSVLCTQAPETYVDVNSPLFFSLGNPDESAFPWQRWRSWNNKASRSKHLLMTRYHPPAGLLS
LRQELVKYLAGARGFHTDPQHIIITNGVQEGLALLARTLLTPQEHIAVESPCYSGAWNLFNSFAPHIHAIPVDDGGLRTD
LLPEQQCALAYVTPSHQYPVGSTLPLARRLALLEWSRRSNAYVIEDDYDTTFLYGTQPLPALKSLEDANNVIYLSSFSKT
LGPGMRLGFMVCPDRLVEPILNLKALWNHGASWLYQQFLADFMQDQGYHRHLRKLELEYAARQKLLREGLSALFPRARLL
GTSSGLHLTLKTDLPAQRVNQLRERCLRDGVRFDTLQSMCNGSECAYMAHNGAPLMLFGFSALSEVKIRRALAIIASAAK
ELGLA

Sequences:

>Translated_485_residues
MLSFTLDRNSPLSLQKQIYQQFHTALHDGSLQCGERLPSIRELGSKLQVSRNTITAVYEKLLQEGFIASRPGVGYNVVQA
SHIDLPESPAAQQELDHPPSVLCTQAPETYVDVNSPLFFSLGNPDESAFPWQRWRSWNNKASRSKHLLMTRYHPPAGLLS
LRQELVKYLAGARGFHTDPQHIIITNGVQEGLALLARTLLTPQEHIAVESPCYSGAWNLFNSFAPHIHAIPVDDGGLRTD
LLPEQQCALAYVTPSHQYPVGSTLPLARRLALLEWSRRSNAYVIEDDYDTTFLYGTQPLPALKSLEDANNVIYLSSFSKT
LGPGMRLGFMVCPDRLVEPILNLKALWNHGASWLYQQFLADFMQDQGYHRHLRKLELEYAARQKLLREGLSALFPRARLL
GTSSGLHLTLKTDLPAQRVNQLRERCLRDGVRFDTLQSMCNGSECAYMAHNGAPLMLFGFSALSEVKIRRALAIIASAAK
ELGLA
>Mature_485_residues
MLSFTLDRNSPLSLQKQIYQQFHTALHDGSLQCGERLPSIRELGSKLQVSRNTITAVYEKLLQEGFIASRPGVGYNVVQA
SHIDLPESPAAQQELDHPPSVLCTQAPETYVDVNSPLFFSLGNPDESAFPWQRWRSWNNKASRSKHLLMTRYHPPAGLLS
LRQELVKYLAGARGFHTDPQHIIITNGVQEGLALLARTLLTPQEHIAVESPCYSGAWNLFNSFAPHIHAIPVDDGGLRTD
LLPEQQCALAYVTPSHQYPVGSTLPLARRLALLEWSRRSNAYVIEDDYDTTFLYGTQPLPALKSLEDANNVIYLSSFSKT
LGPGMRLGFMVCPDRLVEPILNLKALWNHGASWLYQQFLADFMQDQGYHRHLRKLELEYAARQKLLREGLSALFPRARLL
GTSSGLHLTLKTDLPAQRVNQLRERCLRDGVRFDTLQSMCNGSECAYMAHNGAPLMLFGFSALSEVKIRRALAIIASAAK
ELGLA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=393, Percent_Identity=23.1552162849873, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI33469970, Length=393, Percent_Identity=23.1552162849873, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1787710, Length=423, Percent_Identity=26.4775413711584, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790797, Length=419, Percent_Identity=27.2076372315036, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356535, Length=235, Percent_Identity=26.8085106382979, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54267; Mature: 54267

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFTLDRNSPLSLQKQIYQQFHTALHDGSLQCGERLPSIRELGSKLQVSRNTITAVYEK
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LLQEGFIASRPGVGYNVVQASHIDLPESPAAQQELDHPPSVLCTQAPETYVDVNSPLFFS
HHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCEEECCCCCCEEECCCCEEEE
LGNPDESAFPWQRWRSWNNKASRSKHLLMTRYHPPAGLLSLRQELVKYLAGARGFHTDPQ
ECCCCCCCCCHHHHHCCCCHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HIIITNGVQEGLALLARTLLTPQEHIAVESPCYSGAWNLFNSFAPHIHAIPVDDGGLRTD
EEEEECCHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCC
LLPEQQCALAYVTPSHQYPVGSTLPLARRLALLEWSRRSNAYVIEDDYDTTFLYGTQPLP
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCH
ALKSLEDANNVIYLSSFSKTLGPGMRLGFMVCPDRLVEPILNLKALWNHGASWLYQQFLA
HHHHHHCCCCEEEEECCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHH
DFMQDQGYHRHLRKLELEYAARQKLLREGLSALFPRARLLGTSSGLHLTLKTDLPAQRVN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCHHHHH
QLRERCLRDGVRFDTLQSMCNGSECAYMAHNGAPLMLFGFSALSEVKIRRALAIIASAAK
HHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
ELGLA
HHCCC
>Mature Secondary Structure
MLSFTLDRNSPLSLQKQIYQQFHTALHDGSLQCGERLPSIRELGSKLQVSRNTITAVYEK
CEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LLQEGFIASRPGVGYNVVQASHIDLPESPAAQQELDHPPSVLCTQAPETYVDVNSPLFFS
HHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCEEECCCCCCEEECCCCEEEE
LGNPDESAFPWQRWRSWNNKASRSKHLLMTRYHPPAGLLSLRQELVKYLAGARGFHTDPQ
ECCCCCCCCCHHHHHCCCCHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HIIITNGVQEGLALLARTLLTPQEHIAVESPCYSGAWNLFNSFAPHIHAIPVDDGGLRTD
EEEEECCHHHHHHHHHHHHCCCHHHHEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCC
LLPEQQCALAYVTPSHQYPVGSTLPLARRLALLEWSRRSNAYVIEDDYDTTFLYGTQPLP
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCH
ALKSLEDANNVIYLSSFSKTLGPGMRLGFMVCPDRLVEPILNLKALWNHGASWLYQQFLA
HHHHHHCCCCEEEEECCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHH
DFMQDQGYHRHLRKLELEYAARQKLLREGLSALFPRARLLGTSSGLHLTLKTDLPAQRVN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCHHHHH
QLRERCLRDGVRFDTLQSMCNGSECAYMAHNGAPLMLFGFSALSEVKIRRALAIIASAAK
HHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
ELGLA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]