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The map label for this gene is atoS [H]

Identifier: 238920097

GI number: 238920097

Start: 2122855

End: 2124627

Strand: Direct

Name: atoS [H]

Synonym: NT01EI_2203

Alternate gene names: 238920097

Gene position: 2122855-2124627 (Clockwise)

Preceding gene: 238920096

Following gene: 238920098

Centisome position: 55.68

GC content: 62.27

Gene sequence:

>1773_bases
ATGGCGATCCTGCTGGTCATCGTGCCGACGCTGTCGATTGGCTATATCGTCGAGACCGAGGGACGCTCCGCGGTGCTGGC
CGAAAAAGAGAAAAAGCTGGCCGCCGTCGTTCAGCTGCTCGACCAGGCGCTGGAGGGACACTTTGACCATTTCGCGACGC
TGCCGCGCGCTGAGCGTATCCGGGCGCTGAATACCGAGCTCAGCCCCATCACCGAGCGTATCACCCAGGCGTTTCCCGGC
ATCGGCGCGGGCTACTACAGCAAAACGCTGGATGCGATCATTACCTATGCCCCGTTCGCGCTGTATCAAAGCAACGTCGG
CGTGGCCATTGCCGCCGACCACCCCGGACGTGAGGTGATGCGCAGCGATACGCCGCTCGTCTTTTCCGGCCACCAGGTGC
GCGGCGATATCCTCAATTCGATGATCCCGATTAAGCGGGGTGGCGAGGTGCTGGGCTACATCTGGGCCAATGAGCTGACG
CAGGATATCCGTCGTCAGGCCAGACAAATGGATCTGCGTATTATGGCGGTGCTGACGGCGGGCCTGCTGTGCAGCCTGCT
GCTGATCGTCCTCTTCTCACGGCGTTTCAGCGCCCATATCGACATCATCACCGAAGGGCTGTCAGCGCTGGTGCACAAAA
CGCCTGAGCCGCTCCCCGAGCTGCCCGGCGAGCTGGGGCAAATCAGCCGCAGCGTCAACGCACTGGCGCAAACGCTGCGT
GAGACCAAGACCCTTAACGATCTGATCATTGAAAACGCCGCCGACGGGGTGATCGCCATCGACCGGCTGGGCAATCTCAC
CACCATCAACCCGGCGGCTGAGGCCATCACCGGCTATACGCGGGATGAGCTGGTGGGCCAGCCCTACGCCGCTCTGTTCT
CCGGCTCCCATTTCGCCAGTCCGGTGCTGGATACCCTGGCACACGGCACCGAACATCTGGCGCAAGAGGTCAGCTTCCCG
GCGCGTCATCGGACCATTGAACTCAGCGTCACCACCAGCCGCATCCATAACCCCCATGGCGAACTGATGGGGGCGCTGGT
GATCTTTTCCGATCTGACCGCCCGCAAAGAGGCCCAGCGGCGTCTGGCGCAGACCGAAAGGCTTGCCACGCTGGGCGAGC
TGATGGCCGGCGTCGCCCATGAGGTGCGCAACCCGCTGACTGCCATCCGCGGCTATGTGCAGATCATCCGTCAGCAAACC
GCCCTGCCAGCGCATCAGGAGTATCTGTCCGTAGTACTGAAAGAGATTGATTCAATTAATAAAGTCATTCAACAGCTGCT
CGACTTTTCCCGACCGCGGCAAAGCCAGTGGCAGCGGGTGTCGCTCAACGTGCTGATCGAAGAGGCGCTGATCCTGGTGC
AAACCTCCGGGGTTCAGGCGCGGATCACCTTCCACTGCGCGCTGGACAGCACGCTGCCGGCGATCGTGGCCGATCGCGAA
CTGCTCAAGCAGGTACTGCTGAACATCTTAATCAATGCGGTGCAGGCCATCAGCGCGCGCGGCGAGATCCGCATACGCAC
CTGGCAACCCACCCCCGCACAGCAGGCGGTGACCATCACGGACAGCGGCTGCGGCATCGATATCGCGCTGCAGAAAAAAA
TCTTTGACCCCTTCTTCACCACCAAGGCCGCGGGAACCGGCCTTGGGCTGGCCCTGAGCCAGCGCATCATCAACGCCCAC
CGGGGGGATATTGACGTGGCCAGCACGCCGGGAGGCGGTACCGCCTTTACCCTCATGTTACCGACCCATCCGCCGGAGAG
CCCGCCAGAATGA

Upstream 100 bases:

>100_bases
CGCCGATAATGGGGGTTTGCCTACGCCGAGCCACCGGGATACCTGCATGCGCTTTTTAAGAGTGCTATACCCACGACGAT
TACGCAATCAAATGATACTC

Downstream 100 bases:

>100_bases
AATCCCGCTACCGTATCCTCATCGTGGATGACGAAGAGAATGTGCGCCGCATGCTCACCACCGCGTTTGCGCTCCAGGGG
CATGAAACGTACGACGCCAG

Product: sensory histidine kinase AtoS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MAILLVIVPTLSIGYIVETEGRSAVLAEKEKKLAAVVQLLDQALEGHFDHFATLPRAERIRALNTELSPITERITQAFPG
IGAGYYSKTLDAIITYAPFALYQSNVGVAIAADHPGREVMRSDTPLVFSGHQVRGDILNSMIPIKRGGEVLGYIWANELT
QDIRRQARQMDLRIMAVLTAGLLCSLLLIVLFSRRFSAHIDIITEGLSALVHKTPEPLPELPGELGQISRSVNALAQTLR
ETKTLNDLIIENAADGVIAIDRLGNLTTINPAAEAITGYTRDELVGQPYAALFSGSHFASPVLDTLAHGTEHLAQEVSFP
ARHRTIELSVTTSRIHNPHGELMGALVIFSDLTARKEAQRRLAQTERLATLGELMAGVAHEVRNPLTAIRGYVQIIRQQT
ALPAHQEYLSVVLKEIDSINKVIQQLLDFSRPRQSQWQRVSLNVLIEEALILVQTSGVQARITFHCALDSTLPAIVADRE
LLKQVLLNILINAVQAISARGEIRIRTWQPTPAQQAVTITDSGCGIDIALQKKIFDPFFTTKAAGTGLGLALSQRIINAH
RGDIDVASTPGGGTAFTLMLPTHPPESPPE

Sequences:

>Translated_590_residues
MAILLVIVPTLSIGYIVETEGRSAVLAEKEKKLAAVVQLLDQALEGHFDHFATLPRAERIRALNTELSPITERITQAFPG
IGAGYYSKTLDAIITYAPFALYQSNVGVAIAADHPGREVMRSDTPLVFSGHQVRGDILNSMIPIKRGGEVLGYIWANELT
QDIRRQARQMDLRIMAVLTAGLLCSLLLIVLFSRRFSAHIDIITEGLSALVHKTPEPLPELPGELGQISRSVNALAQTLR
ETKTLNDLIIENAADGVIAIDRLGNLTTINPAAEAITGYTRDELVGQPYAALFSGSHFASPVLDTLAHGTEHLAQEVSFP
ARHRTIELSVTTSRIHNPHGELMGALVIFSDLTARKEAQRRLAQTERLATLGELMAGVAHEVRNPLTAIRGYVQIIRQQT
ALPAHQEYLSVVLKEIDSINKVIQQLLDFSRPRQSQWQRVSLNVLIEEALILVQTSGVQARITFHCALDSTLPAIVADRE
LLKQVLLNILINAVQAISARGEIRIRTWQPTPAQQAVTITDSGCGIDIALQKKIFDPFFTTKAAGTGLGLALSQRIINAH
RGDIDVASTPGGGTAFTLMLPTHPPESPPE
>Mature_589_residues
AILLVIVPTLSIGYIVETEGRSAVLAEKEKKLAAVVQLLDQALEGHFDHFATLPRAERIRALNTELSPITERITQAFPGI
GAGYYSKTLDAIITYAPFALYQSNVGVAIAADHPGREVMRSDTPLVFSGHQVRGDILNSMIPIKRGGEVLGYIWANELTQ
DIRRQARQMDLRIMAVLTAGLLCSLLLIVLFSRRFSAHIDIITEGLSALVHKTPEPLPELPGELGQISRSVNALAQTLRE
TKTLNDLIIENAADGVIAIDRLGNLTTINPAAEAITGYTRDELVGQPYAALFSGSHFASPVLDTLAHGTEHLAQEVSFPA
RHRTIELSVTTSRIHNPHGELMGALVIFSDLTARKEAQRRLAQTERLATLGELMAGVAHEVRNPLTAIRGYVQIIRQQTA
LPAHQEYLSVVLKEIDSINKVIQQLLDFSRPRQSQWQRVSLNVLIEEALILVQTSGVQARITFHCALDSTLPAIVADREL
LKQVLLNILINAVQAISARGEIRIRTWQPTPAQQAVTITDSGCGIDIALQKKIFDPFFTTKAAGTGLGLALSQRIINAHR
GDIDVASTPGGGTAFTLMLPTHPPESPPE

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=584, Percent_Identity=78.5958904109589, Blast_Score=922, Evalue=0.0,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=41.49377593361, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI1790300, Length=344, Percent_Identity=28.1976744186047, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI145693157, Length=300, Percent_Identity=28, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=32.3008849557522, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI48994928, Length=392, Percent_Identity=27.0408163265306, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=26.0683760683761, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=29.5774647887324, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=26.1467889908257, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=27.8225806451613, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=29.3388429752066, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=26.9058295964126, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=261, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788279, Length=206, Percent_Identity=25.2427184466019, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64317; Mature: 64186

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00436 PEROXIDASE_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILLVIVPTLSIGYIVETEGRSAVLAEKEKKLAAVVQLLDQALEGHFDHFATLPRAERI
CEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RALNTELSPITERITQAFPGIGAGYYSKTLDAIITYAPFALYQSNVGVAIAADHPGREVM
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHH
RSDTPLVFSGHQVRGDILNSMIPIKRGGEVLGYIWANELTQDIRRQARQMDLRIMAVLTA
HCCCCEEEECCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLCSLLLIVLFSRRFSAHIDIITEGLSALVHKTPEPLPELPGELGQISRSVNALAQTLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHH
ETKTLNDLIIENAADGVIAIDRLGNLTTINPAAEAITGYTRDELVGQPYAALFSGSHFAS
HHHHHHHHHHHCCCCCEEEEECCCCCEECCHHHHHHHCCCHHHHCCCCHHHHHCCCCHHH
PVLDTLAHGTEHLAQEVSFPARHRTIELSVTTSRIHNPHGELMGALVIFSDLTARKEAQR
HHHHHHHCCHHHHHHHCCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLAQTERLATLGELMAGVAHEVRNPLTAIRGYVQIIRQQTALPAHQEYLSVVLKEIDSIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KVIQQLLDFSRPRQSQWQRVSLNVLIEEALILVQTSGVQARITFHCALDSTLPAIVADRE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEECCCHHHHHHHHH
LLKQVLLNILINAVQAISARGEIRIRTWQPTPAQQAVTITDSGCGIDIALQKKIFDPFFT
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEHHHHCCHHHH
TKAAGTGLGLALSQRIINAHRGDIDVASTPGGGTAFTLMLPTHPPESPPE
HHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
AILLVIVPTLSIGYIVETEGRSAVLAEKEKKLAAVVQLLDQALEGHFDHFATLPRAERI
EEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RALNTELSPITERITQAFPGIGAGYYSKTLDAIITYAPFALYQSNVGVAIAADHPGREVM
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHH
RSDTPLVFSGHQVRGDILNSMIPIKRGGEVLGYIWANELTQDIRRQARQMDLRIMAVLTA
HCCCCEEEECCHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLCSLLLIVLFSRRFSAHIDIITEGLSALVHKTPEPLPELPGELGQISRSVNALAQTLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHH
ETKTLNDLIIENAADGVIAIDRLGNLTTINPAAEAITGYTRDELVGQPYAALFSGSHFAS
HHHHHHHHHHHCCCCCEEEEECCCCCEECCHHHHHHHCCCHHHHCCCCHHHHHCCCCHHH
PVLDTLAHGTEHLAQEVSFPARHRTIELSVTTSRIHNPHGELMGALVIFSDLTARKEAQR
HHHHHHHCCHHHHHHHCCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RLAQTERLATLGELMAGVAHEVRNPLTAIRGYVQIIRQQTALPAHQEYLSVVLKEIDSIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KVIQQLLDFSRPRQSQWQRVSLNVLIEEALILVQTSGVQARITFHCALDSTLPAIVADRE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEECCCHHHHHHHHH
LLKQVLLNILINAVQAISARGEIRIRTWQPTPAQQAVTITDSGCGIDIALQKKIFDPFFT
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCEEEEEHHHHCCHHHH
TKAAGTGLGLALSQRIINAHRGDIDVASTPGGGTAFTLMLPTHPPESPPE
HHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]