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The map label for this gene is iolC [H]

Identifier: 238920026

GI number: 238920026

Start: 2056650

End: 2058554

Strand: Reverse

Name: iolC [H]

Synonym: NT01EI_2130

Alternate gene names: 238920026

Gene position: 2058554-2056650 (Counterclockwise)

Preceding gene: 238920027

Following gene: 238920025

Centisome position: 54.0

GC content: 64.2

Gene sequence:

>1905_bases
GTGGAAAAGCAGTTTGATGTGATATGCATGGGGCGGGTCGCCGTTGATCTCTACAGCCAGCAGATTGGCGCGAGGCTTGA
AGATGCGTCGGGTTTTGCCAAATACCTCGGCGGATCGTCGGGAAACGTCGCCTATGGCACGGCGCGCCAGGGGCTGCGCT
CATCGATGCTGGCGCGGGTCGGCGATGAACATATGGGGCGCTTCCTGCGCGAGGAGCTCCGTCAGGCCGGCTGCGATACC
CGCCATCTGATCATCGATAAAGAGCGGCTGACGGCGCTGGTGCTGCTCGGCATCAAGGATCAGGACACCTTCCCGCTGAT
TTTTTACCGCGACAACTGCGCCGACATGGCGATCAGCGCAGACGACGTAGATGAGGCGTACATTGCCTCGTCCCGCTGCC
TGGCGATTACCGGCACGCACCTGTCCCATCCGCAAACCCGCGAGGCGGTGCTGACGGCACTGGGTTACGCCCGTCGTCAC
GGCGTGCGCACGGTGTTGGATATCGACTACCGTCCGGTGCTCTGGGGGCTGACCTCGCTGGGTGACGGCGAAACACGGTT
TATCGCCGCCGATCGGGTGAGCCGTGAGCTACAGGAGGTGCTGCACCTGTTCGACGTTATCGTCGGCACTGAGGAGGAGT
TCCACATCGCGGGCGGCAGCATCGACACGCTACAGGCACTGACGCAGGTGAGACGCGTCAGTCCGGCGACGCTGGTGTGC
AAGCGTGGCGCGCGGGGTTGCTCGGTGTATACCGATGCGATTCCGCCCCGCCTTGATGACGGCCTGACCGTTACCGGCGT
CCGGGTGGCGATCCTCAACGTGCTGGGTGCCGGGGATGCGTTTATGTCCGGACTGCTGCGGGGCTACCTCAACGATGAAG
GCTGGGAGCAGAGCTGCCGCTATGCCAATGCCTGCGGTGCGCTGGTGGTATCACGCCACGGCTGTTCGCCCGCCATGCCG
AGCAAAATCGAGCTTGATGACTATCTGTCACGCGAGCGCGACGTTCCGCGACCGGATCTCGACCCGCGCCTTAACCATTT
GCACCGGGTAACCACCCGTCGCCGCGAGTGGTCTGAGCTATGCGTGATGGCGTTTGACCACCGCAGCCAGCTTGAAGAGA
TGGCGATGCAGTGCGGCGCCAGCCTGAAGCGTATCCCCGTGCTGAAAACGCTGATCCTGCAGGCCAGCCGCGCAGCGGCG
CAGTGTGCCGGGCTTGCGGGAAGGGCCGGGCTGCTGTGCGATGGCACCTTCGGACAGGATGCGCTGAACGCCATAACCGG
CGAGGGCTGGTGGATCGGGCGGCCCATTGAGCTGCCGGGATCACGACCGCTGGAGATGGAGCACGGCAATATTGGCACCC
AGCTGATCAGCTGGCCGCAGGAGCACGTGGTGAAGTGTCTGGTTCTCTACCACCCGGAGGATGTACATGCCCTGCGCCTG
GCGCAGGAGCGGAGCGTGGCGGAGGTCTACCGCGCCTGCTGCCAGTCCGGGCATGAGCTGCTGCTGGAGCTGATTTTACC
GCCCGATATGTCACACAGTGACGATCTCTATCTGCGGGCGGTTTCCCGCTTCTACAACCTGGGGGTTTACCCCGACTGCT
GGAAGCTGCCGCCGCTCTCCTCTGCGGGATGGTCGGCGCTGGAAGCGATCATCGAACGGCGCGATCCGCACTGCCGCGGC
GTGCTTATTCTCGGCCTTGATGCCCCGGCGGAAGAGTTGCGTGCCGGGTTTAACGCCGCGGCCGACCACGCGTGGGTAAA
AGGGTTTGCCGTGGGCCGCACGCTGTTTGGCGACGCCGCCCGCGCGTGGCTGAGGCAGGATATCGACGATGCGCAGCTGG
TGGCGCGCATTCGGGACAACTACCTGCAGCTTATCGCCTGGTGGCGCGAGCGTGGGCAAGCATAA

Upstream 100 bases:

>100_bases
CGAGGGTTGGAAGGTGTCGCGGGTGCTTGACGCTATCGCCCTCTCTCATCGCGAAGGCCGCTGGCTGAACGTGACTGACA
TTGTTTGACGAGGTATCAAC

Downstream 100 bases:

>100_bases
TTAAGGAGAAGGGTATGGCTGTGCAATTAGGTATTAATCCGCTGACATGGACCAACGACGATCTCCCGTCTCTCGGCGCG
GAGACGTCGCTTGAGACCTG

Product: PfkB domain protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MEKQFDVICMGRVAVDLYSQQIGARLEDASGFAKYLGGSSGNVAYGTARQGLRSSMLARVGDEHMGRFLREELRQAGCDT
RHLIIDKERLTALVLLGIKDQDTFPLIFYRDNCADMAISADDVDEAYIASSRCLAITGTHLSHPQTREAVLTALGYARRH
GVRTVLDIDYRPVLWGLTSLGDGETRFIAADRVSRELQEVLHLFDVIVGTEEEFHIAGGSIDTLQALTQVRRVSPATLVC
KRGARGCSVYTDAIPPRLDDGLTVTGVRVAILNVLGAGDAFMSGLLRGYLNDEGWEQSCRYANACGALVVSRHGCSPAMP
SKIELDDYLSRERDVPRPDLDPRLNHLHRVTTRRREWSELCVMAFDHRSQLEEMAMQCGASLKRIPVLKTLILQASRAAA
QCAGLAGRAGLLCDGTFGQDALNAITGEGWWIGRPIELPGSRPLEMEHGNIGTQLISWPQEHVVKCLVLYHPEDVHALRL
AQERSVAEVYRACCQSGHELLLELILPPDMSHSDDLYLRAVSRFYNLGVYPDCWKLPPLSSAGWSALEAIIERRDPHCRG
VLILGLDAPAEELRAGFNAAADHAWVKGFAVGRTLFGDAARAWLRQDIDDAQLVARIRDNYLQLIAWWRERGQA

Sequences:

>Translated_634_residues
MEKQFDVICMGRVAVDLYSQQIGARLEDASGFAKYLGGSSGNVAYGTARQGLRSSMLARVGDEHMGRFLREELRQAGCDT
RHLIIDKERLTALVLLGIKDQDTFPLIFYRDNCADMAISADDVDEAYIASSRCLAITGTHLSHPQTREAVLTALGYARRH
GVRTVLDIDYRPVLWGLTSLGDGETRFIAADRVSRELQEVLHLFDVIVGTEEEFHIAGGSIDTLQALTQVRRVSPATLVC
KRGARGCSVYTDAIPPRLDDGLTVTGVRVAILNVLGAGDAFMSGLLRGYLNDEGWEQSCRYANACGALVVSRHGCSPAMP
SKIELDDYLSRERDVPRPDLDPRLNHLHRVTTRRREWSELCVMAFDHRSQLEEMAMQCGASLKRIPVLKTLILQASRAAA
QCAGLAGRAGLLCDGTFGQDALNAITGEGWWIGRPIELPGSRPLEMEHGNIGTQLISWPQEHVVKCLVLYHPEDVHALRL
AQERSVAEVYRACCQSGHELLLELILPPDMSHSDDLYLRAVSRFYNLGVYPDCWKLPPLSSAGWSALEAIIERRDPHCRG
VLILGLDAPAEELRAGFNAAADHAWVKGFAVGRTLFGDAARAWLRQDIDDAQLVARIRDNYLQLIAWWRERGQA
>Mature_634_residues
MEKQFDVICMGRVAVDLYSQQIGARLEDASGFAKYLGGSSGNVAYGTARQGLRSSMLARVGDEHMGRFLREELRQAGCDT
RHLIIDKERLTALVLLGIKDQDTFPLIFYRDNCADMAISADDVDEAYIASSRCLAITGTHLSHPQTREAVLTALGYARRH
GVRTVLDIDYRPVLWGLTSLGDGETRFIAADRVSRELQEVLHLFDVIVGTEEEFHIAGGSIDTLQALTQVRRVSPATLVC
KRGARGCSVYTDAIPPRLDDGLTVTGVRVAILNVLGAGDAFMSGLLRGYLNDEGWEQSCRYANACGALVVSRHGCSPAMP
SKIELDDYLSRERDVPRPDLDPRLNHLHRVTTRRREWSELCVMAFDHRSQLEEMAMQCGASLKRIPVLKTLILQASRAAA
QCAGLAGRAGLLCDGTFGQDALNAITGEGWWIGRPIELPGSRPLEMEHGNIGTQLISWPQEHVVKCLVLYHPEDVHALRL
AQERSVAEVYRACCQSGHELLLELILPPDMSHSDDLYLRAVSRFYNLGVYPDCWKLPPLSSAGWSALEAIIERRDPHCRG
VLILGLDAPAEELRAGFNAAADHAWVKGFAVGRTLFGDAARAWLRQDIDDAQLVARIRDNYLQLIAWWRERGQA

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1790193, Length=343, Percent_Identity=22.7405247813411, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 70218; Mature: 70218

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQFDVICMGRVAVDLYSQQIGARLEDASGFAKYLGGSSGNVAYGTARQGLRSSMLARV
CCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHH
GDEHMGRFLREELRQAGCDTRHLIIDKERLTALVLLGIKDQDTFPLIFYRDNCADMAISA
CHHHHHHHHHHHHHHCCCCCEEEEEEHHHEEEEEEEECCCCCCCEEEEEECCCCCCEECC
DDVDEAYIASSRCLAITGTHLSHPQTREAVLTALGYARRHGVRTVLDIDYRPVLWGLTSL
CCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCC
GDGETRFIAADRVSRELQEVLHLFDVIVGTEEEFHIAGGSIDTLQALTQVRRVSPATLVC
CCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHH
KRGARGCSVYTDAIPPRLDDGLTVTGVRVAILNVLGAGDAFMSGLLRGYLNDEGWEQSCR
HCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
YANACGALVVSRHGCSPAMPSKIELDDYLSRERDVPRPDLDPRLNHLHRVTTRRREWSEL
HHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CVMAFDHRSQLEEMAMQCGASLKRIPVLKTLILQASRAAAQCAGLAGRAGLLCDGTFGQD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHH
ALNAITGEGWWIGRPIELPGSRPLEMEHGNIGTQLISWPQEHVVKCLVLYHPEDVHALRL
HHHHHCCCCEEECCCEECCCCCCCEECCCCCCHHHHCCCHHHHHEEHEEECCCCHHHHHH
AQERSVAEVYRACCQSGHELLLELILPPDMSHSDDLYLRAVSRFYNLGVYPDCWKLPPLS
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
SAGWSALEAIIERRDPHCRGVLILGLDAPAEELRAGFNAAADHAWVKGFAVGRTLFGDAA
CCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RAWLRQDIDDAQLVARIRDNYLQLIAWWRERGQA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKQFDVICMGRVAVDLYSQQIGARLEDASGFAKYLGGSSGNVAYGTARQGLRSSMLARV
CCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHH
GDEHMGRFLREELRQAGCDTRHLIIDKERLTALVLLGIKDQDTFPLIFYRDNCADMAISA
CHHHHHHHHHHHHHHCCCCCEEEEEEHHHEEEEEEEECCCCCCCEEEEEECCCCCCEECC
DDVDEAYIASSRCLAITGTHLSHPQTREAVLTALGYARRHGVRTVLDIDYRPVLWGLTSL
CCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCC
GDGETRFIAADRVSRELQEVLHLFDVIVGTEEEFHIAGGSIDTLQALTQVRRVSPATLVC
CCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHH
KRGARGCSVYTDAIPPRLDDGLTVTGVRVAILNVLGAGDAFMSGLLRGYLNDEGWEQSCR
HCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
YANACGALVVSRHGCSPAMPSKIELDDYLSRERDVPRPDLDPRLNHLHRVTTRRREWSEL
HHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CVMAFDHRSQLEEMAMQCGASLKRIPVLKTLILQASRAAAQCAGLAGRAGLLCDGTFGQD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHH
ALNAITGEGWWIGRPIELPGSRPLEMEHGNIGTQLISWPQEHVVKCLVLYHPEDVHALRL
HHHHHCCCCEEECCCEECCCCCCCEECCCCCCHHHHCCCHHHHHEEHEEECCCCHHHHHH
AQERSVAEVYRACCQSGHELLLELILPPDMSHSDDLYLRAVSRFYNLGVYPDCWKLPPLS
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
SAGWSALEAIIERRDPHCRGVLILGLDAPAEELRAGFNAAADHAWVKGFAVGRTLFGDAA
CCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RAWLRQDIDDAQLVARIRDNYLQLIAWWRERGQA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA