Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 238920022

GI number: 238920022

Start: 2051571

End: 2052482

Strand: Reverse

Name: htpX [H]

Synonym: NT01EI_2126

Alternate gene names: 238920022

Gene position: 2052482-2051571 (Counterclockwise)

Preceding gene: 238920023

Following gene: 238920021

Centisome position: 53.84

GC content: 59.76

Gene sequence:

>912_bases
ATGTTTGAGAGGATTGATGACGATATGATGCGTATTGCTTTGTTCCTGTTGACCAACCTGGCCGTGATGCTGGTGTTCGG
TCTGGTGCTGAGCCTGACAGGCATTCGTTCCAGCAGCGTGCAGGGACTGATGATCATGGCACTGCTGTTCGGTTTTGGCG
GCTCCATTGTTTCTCTGCTGATGTCCAAGTGGATGGCGCTGCGCTCCGTTGGCGGCGAGGTGATTGAGCAGCCGCGCAAT
GAAACCGAACGCTGGCTGGTCGAGACGGTACGCCGTCAGGCCCAGCAGGCCGGTATCGGCATGCCGCAGGTTGCCATCTA
TCACGCTCCGGATATCAATGCGTTCGCCACCGGCGCCCGGCGCGATGCCTCGCTGGTCGCGGTGAGCACCGGCCTGCTGC
AGAGCATGAGCCGCGATGAGGCCGAGGCGGTGCTGGCACATGAGATCAGCCATGTCGCCAACGGCGACATGGTGACGATG
ACGCTGGTGCAGGGGGTGGTGAACACCTTCGTGATCTTTATTTCCCGCCTGATAGCCCAGGTGGCGGCAGGTTTTCTCTC
TGGCAACCGCGATGAGGGTGAGGGCGAGAGCAGCGGCAACCCGATGATCTATTTCGCCGTTTCCATGGTGTTGGAGCTGG
TGTTTGGCATTCTGGCCAGCATCATTACCATGTGGTTCTCGCGCTACCGTGAGTTTCGCGCCGATGCCGGGTCAGCCGGC
CTGGTCGGTCGCGAGAAGATGATCGCTGCGCTACAGCGTCTGAAGACCAGCTATGAGCCGCAGGAAGCCGGCAGCATGAT
GGCTTTCTGTATCAACGGTCGTGGTAATCGTACCTTTGGCGAGCTGTTCCTGTCGCATCCGCCGCTGGATAAGCGCATCG
AGGCGCTGCGCAGCGGCCAGTATCTGAAGTAA

Upstream 100 bases:

>100_bases
CAGCGTAAATGTAAAGTTGTGTTTCTTTACCCCGTTATTGCACCGTAGCCCTTGAAACCGGCGCAGATGGCCTTACCATC
TGATCATCGCATGGTGCGAT

Downstream 100 bases:

>100_bases
TGACCGATCGCACGTCGCGCGCGGCGGTGTGACTTAGAGCCGCTAACAAAACCGAGTTGATTCGAATAACATCAATTCCC
ATATAGTAGGCATGACACGA

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MFERIDDDMMRIALFLLTNLAVMLVFGLVLSLTGIRSSSVQGLMIMALLFGFGGSIVSLLMSKWMALRSVGGEVIEQPRN
ETERWLVETVRRQAQQAGIGMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQSMSRDEAEAVLAHEISHVANGDMVTM
TLVQGVVNTFVIFISRLIAQVAAGFLSGNRDEGEGESSGNPMIYFAVSMVLELVFGILASIITMWFSRYREFRADAGSAG
LVGREKMIAALQRLKTSYEPQEAGSMMAFCINGRGNRTFGELFLSHPPLDKRIEALRSGQYLK

Sequences:

>Translated_303_residues
MFERIDDDMMRIALFLLTNLAVMLVFGLVLSLTGIRSSSVQGLMIMALLFGFGGSIVSLLMSKWMALRSVGGEVIEQPRN
ETERWLVETVRRQAQQAGIGMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQSMSRDEAEAVLAHEISHVANGDMVTM
TLVQGVVNTFVIFISRLIAQVAAGFLSGNRDEGEGESSGNPMIYFAVSMVLELVFGILASIITMWFSRYREFRADAGSAG
LVGREKMIAALQRLKTSYEPQEAGSMMAFCINGRGNRTFGELFLSHPPLDKRIEALRSGQYLK
>Mature_303_residues
MFERIDDDMMRIALFLLTNLAVMLVFGLVLSLTGIRSSSVQGLMIMALLFGFGGSIVSLLMSKWMALRSVGGEVIEQPRN
ETERWLVETVRRQAQQAGIGMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQSMSRDEAEAVLAHEISHVANGDMVTM
TLVQGVVNTFVIFISRLIAQVAAGFLSGNRDEGEGESSGNPMIYFAVSMVLELVFGILASIITMWFSRYREFRADAGSAG
LVGREKMIAALQRLKTSYEPQEAGSMMAFCINGRGNRTFGELFLSHPPLDKRIEALRSGQYLK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=295, Percent_Identity=86.4406779661017, Blast_Score=520, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 33183; Mature: 33183

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERIDDDMMRIALFLLTNLAVMLVFGLVLSLTGIRSSSVQGLMIMALLFGFGGSIVSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHH
MSKWMALRSVGGEVIEQPRNETERWLVETVRRQAQQAGIGMPQVAIYHAPDINAFATGAR
HHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCC
RDASLVAVSTGLLQSMSRDEAEAVLAHEISHVANGDMVTMTLVQGVVNTFVIFISRLIAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAAGFLSGNRDEGEGESSGNPMIYFAVSMVLELVFGILASIITMWFSRYREFRADAGSAG
HHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVGREKMIAALQRLKTSYEPQEAGSMMAFCINGRGNRTFGELFLSHPPLDKRIEALRSGQ
CCHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHCCC
YLK
CCC
>Mature Secondary Structure
MFERIDDDMMRIALFLLTNLAVMLVFGLVLSLTGIRSSSVQGLMIMALLFGFGGSIVSLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHH
MSKWMALRSVGGEVIEQPRNETERWLVETVRRQAQQAGIGMPQVAIYHAPDINAFATGAR
HHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHCCCC
RDASLVAVSTGLLQSMSRDEAEAVLAHEISHVANGDMVTMTLVQGVVNTFVIFISRLIAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAAGFLSGNRDEGEGESSGNPMIYFAVSMVLELVFGILASIITMWFSRYREFRADAGSAG
HHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVGREKMIAALQRLKTSYEPQEAGSMMAFCINGRGNRTFGELFLSHPPLDKRIEALRSGQ
CCHHHHHHHHHHHHHHCCCHHHHCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHCCC
YLK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA