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The map label for this gene is mppA [H]

Identifier: 238919737

GI number: 238919737

Start: 1778800

End: 1780419

Strand: Direct

Name: mppA [H]

Synonym: NT01EI_1841

Alternate gene names: 238919737

Gene position: 1778800-1780419 (Clockwise)

Preceding gene: 238919735

Following gene: 238919738

Centisome position: 46.66

GC content: 58.89

Gene sequence:

>1620_bases
ATGCAGCTTTTTCGTCTGGCCGTCGCGGCGGCCGTTGGGGTCGTCGCCGTAAGTCAAAGCGTCCTGGCGGCGCAGGTACC
GCCAGGTACCGTGCTGGCCGAGACGCAGAGCGTGGTACGCCAACTGAAGGATGAGCCGGTGTCGCTGGATCCCGTCGCCG
CCGTCGGATTGCCGGAGGCACAGGTGCTGCGCGATCTGTTTGAGGGGCTGGTTAATCAAGGGGAAGATGGCAGCATCCAG
CCCGGCGTGGCCTATGCCTGGCAGAGTAAGGATCAGCAGCGCTATGTATTTCATCTGCGCGATACGGCACGCTGGTCCAA
CGGCGATCCCGTGACAGCCTACGACTTTGTCTATTCCTGGCGGCGTCTGGTTGATCCGAAGACCCATTCCCCCTTTGCCT
GGTTTGCCGAGACGGCGGGGATCGCCAACGCCGCGGAGATTGTCAGCGGAAAACTGCCCCCCGATCGACTGGGTGTGACG
GCTCTGGATGCCCATACGCTGGTGGTGCAGCTGAATTTCCCGCTGTCCTATTTCCCACAGCTTTGCGCCCATTTCAGTCT
GCTCCCACAGCCACAGAAGGTGGTTGAGCGCTATGGCCAGTCGTGGACGCGTCCGGGTAACCTGGTGGGTAACGGCGCTT
TCCAGCTGAAGCAGCATGTGGTCAACGAACATATCGTGCTGACGCCGAACCCCTATTACTGGGATAAGGCCCATACTCAA
CTGACAAAGGTGACCTTTGTTTTAATAAACCAAGAGAGCACGGCGACCAAACGCTATCTGGCCGGGGATCTGGATATCAC
CGAGTCTTTTCCGAAAAACATGTATCAGACGCTGAAAAAGCGCATTCCCGGTGAGGTGTTTACGCCGATTCAGCTGGGGA
CCTACTACTATGCGTTCAATACCCGCCGCGCGCCGTTGAACGATGTGCGGGTGCGACGTGCGCTCTCCTATGCCATCGAT
CGCGAGATTATCGCCGGCAAGGTGCTGGGCAGTGGGGAGAAGCCCGCCTATCGGCTGACGCCGGATGCGACAAACGGTAT
GGCGCCGCAGCAGCTGCCGATGCAGCTGATGAGTCAGGCAGAGCGTAACCGTCAGGCGCAGGCCTGGCTGCACGAGGCGG
GCTACGGGCCATCGCGGCCGCTCCGGCTGTCGCTGCTGTATAACACAGCGGAGAATAACCAGAAAATTGCCATCGCCGTG
GCATCAATGTGGAAAAAGACCTTGGGGGTTCAGGTTGAGCTGACCAATCAGGAGTGGAAAACCTATGTTGATAACCGTCA
CAGCGGTCGGTTTGACGTGGTACGTGGGTCGTGGATTGCTGACTATAATGAGCCCTCCAGCTTTCTGGGGTTGCTGGGGA
GCCACAACAGCGGCAACCTGACCGGCTTTAGCCAGCCGGGATACGATGCGCTGCTGCTGCAGGCCGCGCGGGAAGGCAAT
GCGCAGAAGCGTAGCGCCATATACCAACAGGCGGAGCGCATGCTGGCAGAGGAGGCGCCGATCGCCCCTCTGTATCAGTA
CACCAATGCTAGGTTGATTAAGCCTTGGGTAAAGGGATACCCCATCAATAATCCGGAGGATGTCGCCTACAGCCGCCAGC
TGTATATCATAAAGCACTAG

Upstream 100 bases:

>100_bases
AAGTGGGGGTGGTGATGAATGCACGCTTCAGGCAGAGTAGGGTAGCGTGGCACCAACCGGGCGCCCTACGGGCAGTGTGA
TCAACATAGGATAGTAAACG

Downstream 100 bases:

>100_bases
CCCGTATTATTCCGCTGGATGACGATATTGTCCTCGTTGGCCATGGCTCTAAAATAAGAGTGCCATGGCCATTCTATTCT
GCTTATTTAAAGAAAGAACA

Product: periplasmic murein peptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MQLFRLAVAAAVGVVAVSQSVLAAQVPPGTVLAETQSVVRQLKDEPVSLDPVAAVGLPEAQVLRDLFEGLVNQGEDGSIQ
PGVAYAWQSKDQQRYVFHLRDTARWSNGDPVTAYDFVYSWRRLVDPKTHSPFAWFAETAGIANAAEIVSGKLPPDRLGVT
ALDAHTLVVQLNFPLSYFPQLCAHFSLLPQPQKVVERYGQSWTRPGNLVGNGAFQLKQHVVNEHIVLTPNPYYWDKAHTQ
LTKVTFVLINQESTATKRYLAGDLDITESFPKNMYQTLKKRIPGEVFTPIQLGTYYYAFNTRRAPLNDVRVRRALSYAID
REIIAGKVLGSGEKPAYRLTPDATNGMAPQQLPMQLMSQAERNRQAQAWLHEAGYGPSRPLRLSLLYNTAENNQKIAIAV
ASMWKKTLGVQVELTNQEWKTYVDNRHSGRFDVVRGSWIADYNEPSSFLGLLGSHNSGNLTGFSQPGYDALLLQAAREGN
AQKRSAIYQQAERMLAEEAPIAPLYQYTNARLIKPWVKGYPINNPEDVAYSRQLYIIKH

Sequences:

>Translated_539_residues
MQLFRLAVAAAVGVVAVSQSVLAAQVPPGTVLAETQSVVRQLKDEPVSLDPVAAVGLPEAQVLRDLFEGLVNQGEDGSIQ
PGVAYAWQSKDQQRYVFHLRDTARWSNGDPVTAYDFVYSWRRLVDPKTHSPFAWFAETAGIANAAEIVSGKLPPDRLGVT
ALDAHTLVVQLNFPLSYFPQLCAHFSLLPQPQKVVERYGQSWTRPGNLVGNGAFQLKQHVVNEHIVLTPNPYYWDKAHTQ
LTKVTFVLINQESTATKRYLAGDLDITESFPKNMYQTLKKRIPGEVFTPIQLGTYYYAFNTRRAPLNDVRVRRALSYAID
REIIAGKVLGSGEKPAYRLTPDATNGMAPQQLPMQLMSQAERNRQAQAWLHEAGYGPSRPLRLSLLYNTAENNQKIAIAV
ASMWKKTLGVQVELTNQEWKTYVDNRHSGRFDVVRGSWIADYNEPSSFLGLLGSHNSGNLTGFSQPGYDALLLQAAREGN
AQKRSAIYQQAERMLAEEAPIAPLYQYTNARLIKPWVKGYPINNPEDVAYSRQLYIIKH
>Mature_539_residues
MQLFRLAVAAAVGVVAVSQSVLAAQVPPGTVLAETQSVVRQLKDEPVSLDPVAAVGLPEAQVLRDLFEGLVNQGEDGSIQ
PGVAYAWQSKDQQRYVFHLRDTARWSNGDPVTAYDFVYSWRRLVDPKTHSPFAWFAETAGIANAAEIVSGKLPPDRLGVT
ALDAHTLVVQLNFPLSYFPQLCAHFSLLPQPQKVVERYGQSWTRPGNLVGNGAFQLKQHVVNEHIVLTPNPYYWDKAHTQ
LTKVTFVLINQESTATKRYLAGDLDITESFPKNMYQTLKKRIPGEVFTPIQLGTYYYAFNTRRAPLNDVRVRRALSYAID
REIIAGKVLGSGEKPAYRLTPDATNGMAPQQLPMQLMSQAERNRQAQAWLHEAGYGPSRPLRLSLLYNTAENNQKIAIAV
ASMWKKTLGVQVELTNQEWKTYVDNRHSGRFDVVRGSWIADYNEPSSFLGLLGSHNSGNLTGFSQPGYDALLLQAAREGN
AQKRSAIYQQAERMLAEEAPIAPLYQYTNARLIKPWVKGYPINNPEDVAYSRQLYIIKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=532, Percent_Identity=63.5338345864662, Blast_Score=706, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=535, Percent_Identity=46.7289719626168, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1789397, Length=518, Percent_Identity=44.2084942084942, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1787762, Length=518, Percent_Identity=24.7104247104247, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789966, Length=481, Percent_Identity=23.0769230769231, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789887, Length=484, Percent_Identity=23.7603305785124, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1787551, Length=451, Percent_Identity=23.5033259423503, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60253; Mature: 60253

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLFRLAVAAAVGVVAVSQSVLAAQVPPGTVLAETQSVVRQLKDEPVSLDPVAAVGLPEA
CHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QVLRDLFEGLVNQGEDGSIQPGVAYAWQSKDQQRYVFHLRDTARWSNGDPVTAYDFVYSW
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHH
RRLVDPKTHSPFAWFAETAGIANAAEIVSGKLPPDRLGVTALDAHTLVVQLNFPLSYFPQ
HHHCCCCCCCCHHHHHHHCCCCHHHHHHCCCCCHHHCCEEEEECEEEEEEECCCHHHHHH
LCAHFSLLPQPQKVVERYGQSWTRPGNLVGNGAFQLKQHVVNEHIVLTPNPYYWDKAHTQ
HHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCEEEECCCCCCCCHHHHE
LTKVTFVLINQESTATKRYLAGDLDITESFPKNMYQTLKKRIPGEVFTPIQLGTYYYAFN
EEEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEECCEEECEEEEEEE
TRRAPLNDVRVRRALSYAIDREIIAGKVLGSGEKPAYRLTPDATNGMAPQQLPMQLMSQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHH
ERNRQAQAWLHEAGYGPSRPLRLSLLYNTAENNQKIAIAVASMWKKTLGVQVELTNQEWK
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHCEEEEECCCHHH
TYVDNRHSGRFDVVRGSWIADYNEPSSFLGLLGSHNSGNLTGFSQPGYDALLLQAAREGN
HHHCCCCCCCEEEEECCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCC
AQKRSAIYQQAERMLAEEAPIAPLYQYTNARLIKPWVKGYPINNPEDVAYSRQLYIIKH
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MQLFRLAVAAAVGVVAVSQSVLAAQVPPGTVLAETQSVVRQLKDEPVSLDPVAAVGLPEA
CHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
QVLRDLFEGLVNQGEDGSIQPGVAYAWQSKDQQRYVFHLRDTARWSNGDPVTAYDFVYSW
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHH
RRLVDPKTHSPFAWFAETAGIANAAEIVSGKLPPDRLGVTALDAHTLVVQLNFPLSYFPQ
HHHCCCCCCCCHHHHHHHCCCCHHHHHHCCCCCHHHCCEEEEECEEEEEEECCCHHHHHH
LCAHFSLLPQPQKVVERYGQSWTRPGNLVGNGAFQLKQHVVNEHIVLTPNPYYWDKAHTQ
HHHHHCCCCCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHCCEEEECCCCCCCCHHHHE
LTKVTFVLINQESTATKRYLAGDLDITESFPKNMYQTLKKRIPGEVFTPIQLGTYYYAFN
EEEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEECCEEECEEEEEEE
TRRAPLNDVRVRRALSYAIDREIIAGKVLGSGEKPAYRLTPDATNGMAPQQLPMQLMSQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHH
ERNRQAQAWLHEAGYGPSRPLRLSLLYNTAENNQKIAIAVASMWKKTLGVQVELTNQEWK
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHCEEEEECCCHHH
TYVDNRHSGRFDVVRGSWIADYNEPSSFLGLLGSHNSGNLTGFSQPGYDALLLQAAREGN
HHHCCCCCCCEEEEECCEEECCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCC
AQKRSAIYQQAERMLAEEAPIAPLYQYTNARLIKPWVKGYPINNPEDVAYSRQLYIIKH
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]