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The map label for this gene is exuT [H]

Identifier: 238919679

GI number: 238919679

Start: 1723998

End: 1725287

Strand: Reverse

Name: exuT [H]

Synonym: NT01EI_1780

Alternate gene names: 238919679

Gene position: 1725287-1723998 (Counterclockwise)

Preceding gene: 238919680

Following gene: 238919675

Centisome position: 45.26

GC content: 57.6

Gene sequence:

>1290_bases
ATGAAAAAGATCAAGAATTTTCGGTGGTATATGATCTTGCTGGTCTGCTTCATTACCATCATTAACTACCTCGACAGAAC
CGCGCTCGGTATCGCGGCACCCACGATCATGGAGAGCACCGGGATCACCAAAGAGCAGTACTCCTGGGTGGTCAGCGCCT
TTCAGCTGGCCTACACAATTGGTCAACCAATCATGGGATTCTTCATTGATACCATCGGTCTGAAGATCGGCTTCTTTATC
TGCGCCATCGTCTGGGGGCTGGCCACCATGGGACATGCGCTGACGGGTACCTGGCAGGGGCTGGCCTTTATGCGCGGCCT
GATGGGATTCAGCGAGGCCTCCGCCATTCCTTCCGGCATCAAAACGGCGTCGACGTGGTTTCCGGCCAAAGAGCGCGGCA
TTGCCACCGGGGTCTTCAACATGGGCACCTCATTCGGCGCCATGCTGGCGCCGCCGCTGATTGCCTGGTGTATTCTGTTC
CACAGCTGGCAATTCGCGTTTATCGTCTCCGGTAGCCTGGCTATCATCGCCGCCTTCGTCTGGTATTTTTGCTATAAGGA
CCCTCAAGAGGCCAAACGCCTCTCCGATGAAGAACGCCGCTATATTGAAGCTGGCCAAGAGTCGTTTCTACAATCCGCCA
GCCAAGAGAAAACCTCAGTGCGCCATATCATCACCCAGCGCAACTTCTGGGGAATCGGCATCGCCCGCTTCCTGGCCGAT
CCGGCCTGGGGAACCATTAACTTCTGGGTACCCATCTTCTTCGTGGAGACCCTGCACTTCAGTCTGAAAGAGATCGCCAT
GTTTGTCTGGTTGCCCTTCCTGATGGCGGATCTCGGTTGTCTGGCCAGCGGCTTTGTGGCCCGTTTTTTCAACGACAGGG
GCATCACCCTGATCAACTCGCGCCGTATCACCTTTACGCTTGGCGCGCTGCTGATGACCACCATCGGTCTGGTCAGTATC
GTGGAAAATCCCTATATCGCGGTGCTGCTGATCAGCATCGGCGGCTTCGCCCACCAGCTGCTGTCGACGGTTGCCGCGAC
GCTGGGAGCGGATTTGTTTAAGAAGAACGAGGTGGCGACGGCGGTCGGGATGGCCGGGGCCTGCGCCTGGTCCGGTCAGC
TCATCTTCAACCTATTTATCGGCGCCTTCGTCAGCATCATCGGCTTTGGCCCCTTCTTTATCGCCCTGGCGGTATTCGAC
CTGATCGGCGCCCTGGCGTTATGGCTGCTGATAGTCGACCGCCAGCCCATCTCTCACGGCAGCGGCACCACACTGGCCGG
GCAGCGCTGA

Upstream 100 bases:

>100_bases
ATTGTTCACGATGCGGAGACCCGCTGATTTACGCATTGGCAAGGCTGTGGCACAACCCCGTAAATAACAAAATCAACAAA
CGAATCCAAAAGAGATTACT

Downstream 100 bases:

>100_bases
AGCCCGGCAGGACGGCGGGCACGATGCCGCCCTGTGCATCCGGGGTTAACGGTTCAGGATCCGGATAGAGCGGATGTGGT
CGTTAAACCCGGTCGCCTCC

Product: hypothetical protein

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKKIKNFRWYMILLVCFITIINYLDRTALGIAAPTIMESTGITKEQYSWVVSAFQLAYTIGQPIMGFFIDTIGLKIGFFI
CAIVWGLATMGHALTGTWQGLAFMRGLMGFSEASAIPSGIKTASTWFPAKERGIATGVFNMGTSFGAMLAPPLIAWCILF
HSWQFAFIVSGSLAIIAAFVWYFCYKDPQEAKRLSDEERRYIEAGQESFLQSASQEKTSVRHIITQRNFWGIGIARFLAD
PAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLMADLGCLASGFVARFFNDRGITLINSRRITFTLGALLMTTIGLVSI
VENPYIAVLLISIGGFAHQLLSTVAATLGADLFKKNEVATAVGMAGACAWSGQLIFNLFIGAFVSIIGFGPFFIALAVFD
LIGALALWLLIVDRQPISHGSGTTLAGQR

Sequences:

>Translated_429_residues
MKKIKNFRWYMILLVCFITIINYLDRTALGIAAPTIMESTGITKEQYSWVVSAFQLAYTIGQPIMGFFIDTIGLKIGFFI
CAIVWGLATMGHALTGTWQGLAFMRGLMGFSEASAIPSGIKTASTWFPAKERGIATGVFNMGTSFGAMLAPPLIAWCILF
HSWQFAFIVSGSLAIIAAFVWYFCYKDPQEAKRLSDEERRYIEAGQESFLQSASQEKTSVRHIITQRNFWGIGIARFLAD
PAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLMADLGCLASGFVARFFNDRGITLINSRRITFTLGALLMTTIGLVSI
VENPYIAVLLISIGGFAHQLLSTVAATLGADLFKKNEVATAVGMAGACAWSGQLIFNLFIGAFVSIIGFGPFFIALAVFD
LIGALALWLLIVDRQPISHGSGTTLAGQR
>Mature_429_residues
MKKIKNFRWYMILLVCFITIINYLDRTALGIAAPTIMESTGITKEQYSWVVSAFQLAYTIGQPIMGFFIDTIGLKIGFFI
CAIVWGLATMGHALTGTWQGLAFMRGLMGFSEASAIPSGIKTASTWFPAKERGIATGVFNMGTSFGAMLAPPLIAWCILF
HSWQFAFIVSGSLAIIAAFVWYFCYKDPQEAKRLSDEERRYIEAGQESFLQSASQEKTSVRHIITQRNFWGIGIARFLAD
PAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLMADLGCLASGFVARFFNDRGITLINSRRITFTLGALLMTTIGLVSI
VENPYIAVLLISIGGFAHQLLSTVAATLGADLFKKNEVATAVGMAGACAWSGQLIFNLFIGAFVSIIGFGPFFIALAVFD
LIGALALWLLIVDRQPISHGSGTTLAGQR

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=338, Percent_Identity=26.3313609467456, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI9966811, Length=247, Percent_Identity=28.3400809716599, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI154350196, Length=362, Percent_Identity=23.2044198895028, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9945322, Length=351, Percent_Identity=25.3561253561254, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI2367193, Length=424, Percent_Identity=49.0566037735849, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI87082320, Length=420, Percent_Identity=27.8571428571429, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789515, Length=401, Percent_Identity=25.4364089775561, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI2367379, Length=345, Percent_Identity=28.9855072463768, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1789152, Length=447, Percent_Identity=24.1610738255034, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082071, Length=233, Percent_Identity=26.1802575107296, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788573, Length=389, Percent_Identity=23.1362467866324, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=284, Percent_Identity=24.6478873239437, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583789, Length=300, Percent_Identity=24, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550460, Length=401, Percent_Identity=25.1870324189526, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655255, Length=379, Percent_Identity=26.1213720316623, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658658, Length=400, Percent_Identity=23.25, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584153, Length=271, Percent_Identity=25.0922509225092, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI20130135, Length=340, Percent_Identity=25, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24655271, Length=340, Percent_Identity=25, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24641682, Length=299, Percent_Identity=24.0802675585284, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130167, Length=350, Percent_Identity=22.2857142857143, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648416, Length=348, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356189, Length=348, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573299, Length=320, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658666, Length=292, Percent_Identity=27.0547945205479, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129235, Length=281, Percent_Identity=25.6227758007117, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639764, Length=406, Percent_Identity=22.4137931034483, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24580790, Length=241, Percent_Identity=24.0663900414938, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24653727, Length=276, Percent_Identity=23.9130434782609, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47194; Mature: 47194

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKNFRWYMILLVCFITIINYLDRTALGIAAPTIMESTGITKEQYSWVVSAFQLAYTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GQPIMGFFIDTIGLKIGFFICAIVWGLATMGHALTGTWQGLAFMRGLMGFSEASAIPSGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
KTASTWFPAKERGIATGVFNMGTSFGAMLAPPLIAWCILFHSWQFAFIVSGSLAIIAAFV
CHHHCCCCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHH
WYFCYKDPQEAKRLSDEERRYIEAGQESFLQSASQEKTSVRHIITQRNFWGIGIARFLAD
HHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
PAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLMADLGCLASGFVARFFNDRGITLINS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
RRITFTLGALLMTTIGLVSIVENPYIAVLLISIGGFAHQLLSTVAATLGADLFKKNEVAT
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AVGMAGACAWSGQLIFNLFIGAFVSIIGFGPFFIALAVFDLIGALALWLLIVDRQPISHG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SGTTLAGQR
CCCCCCCCC
>Mature Secondary Structure
MKKIKNFRWYMILLVCFITIINYLDRTALGIAAPTIMESTGITKEQYSWVVSAFQLAYTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GQPIMGFFIDTIGLKIGFFICAIVWGLATMGHALTGTWQGLAFMRGLMGFSEASAIPSGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
KTASTWFPAKERGIATGVFNMGTSFGAMLAPPLIAWCILFHSWQFAFIVSGSLAIIAAFV
CHHHCCCCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHH
WYFCYKDPQEAKRLSDEERRYIEAGQESFLQSASQEKTSVRHIITQRNFWGIGIARFLAD
HHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
PAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLMADLGCLASGFVARFFNDRGITLINS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
RRITFTLGALLMTTIGLVSIVENPYIAVLLISIGGFAHQLLSTVAATLGADLFKKNEVAT
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AVGMAGACAWSGQLIFNLFIGAFVSIIGFGPFFIALAVFDLIGALALWLLIVDRQPISHG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SGTTLAGQR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]