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The map label for this gene is iolC [H]

Identifier: 238919658

GI number: 238919658

Start: 1707369

End: 1708364

Strand: Reverse

Name: iolC [H]

Synonym: NT01EI_1759

Alternate gene names: 238919658

Gene position: 1708364-1707369 (Counterclockwise)

Preceding gene: 238919659

Following gene: 238919656

Centisome position: 44.81

GC content: 55.12

Gene sequence:

>996_bases
ATGCATAAACGTCGGGGGATCATTGCGATCGGCAATTTGATAGTCGATCAGTCGCTGCGTTGCACGGAATATCCACAGGA
GTCGATGCTGACGCAAATTACCCACGTCGACAAAAGCTGCGGCGGTGGTTGTACCAACGTTTTGTTCGGCCTCTCCCGTA
TCGATCCCTCTCTGCCGCTGGCGCTTAGCGGCGTGATCGGGCGCGATACGTACGGTGACTTTATCTTGCAGGAGACCGCG
CGGCATAATGTCAGCACCTCACGGGTGCATGTTTCAGCTCAGGATGTGACCTCATTCACCTATGTCATGGTGAATAGCCA
AAATGGTAACCGTACATTTTTCCATCACATGGGCGCTAACCATCGGCTTGGCGCGACGGACTTCAGCAATCTGGACAGCC
AGGCACGGATTGCCCACGTTGCTTATCTACTGCTGTTGCCCGCACTCGAACAGGAGGATCGCCAGTGGCAAACCTGCGGC
GCGCGGGCATTGGCGGATCTGCAACGTCAAGGATTTGCAGTGTCGCTTGATCTAGTCTCTGCGCCTGAAACCGAACGCTA
TCAACGCTGGGTAAAACCGGTTTTACCTTACGTTGATTACTTGATCATCAATGATCAGGAGGCCCGTCGCCTGTGTCAAC
GGCCTGGGGATGACGATTATATCGCGCAGGCGCGCAGCCTGCTACAGATGGGCGTACGCAAGCTGGTCTGTATTCACTTT
CCACAGGGTGCGGTTGCCATTGATGCCGAGGGTAAAACCTACAAGGCCGACGCCTATCATGTTCCATCACATGAGGTCGT
GAGCACTTTGGGCGCCGGTGACGCTTTTTGCGCCGGCATGCTGTACGGCATCCATGAGGAATGGCCGCTGGCTGACGCTC
TGCGTTTGGGATGCGCCTGCGCACATTTCAATTTATTTAGCCTCTCAGCGACGGAGGGCGCGCGTACGCTCAGCGAGCTT
CATGACTTTATACAGCATGAGGAGAGCCAGATATGA

Upstream 100 bases:

>100_bases
GACCACTACCTGCTGCTGATGAAAGAGGTCGAGCATGGCGTTAGCACCACCGTCGCAGAGCAAATGGCCATCTTCGGCAG
TCTGGGCAAGGCAGACGGCT

Downstream 100 bases:

>100_bases
CCTCATATGGACTACGGTGCTGACAGCACCACGCGCTACAGCGCTTTAGCATACCGAAAAGCGGCGATGATGAAATCCTC
GTCAAAGTGGAAGGATGCGG

Product: PfkB domain protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MHKRRGIIAIGNLIVDQSLRCTEYPQESMLTQITHVDKSCGGGCTNVLFGLSRIDPSLPLALSGVIGRDTYGDFILQETA
RHNVSTSRVHVSAQDVTSFTYVMVNSQNGNRTFFHHMGANHRLGATDFSNLDSQARIAHVAYLLLLPALEQEDRQWQTCG
ARALADLQRQGFAVSLDLVSAPETERYQRWVKPVLPYVDYLIINDQEARRLCQRPGDDDYIAQARSLLQMGVRKLVCIHF
PQGAVAIDAEGKTYKADAYHVPSHEVVSTLGAGDAFCAGMLYGIHEEWPLADALRLGCACAHFNLFSLSATEGARTLSEL
HDFIQHEESQI

Sequences:

>Translated_331_residues
MHKRRGIIAIGNLIVDQSLRCTEYPQESMLTQITHVDKSCGGGCTNVLFGLSRIDPSLPLALSGVIGRDTYGDFILQETA
RHNVSTSRVHVSAQDVTSFTYVMVNSQNGNRTFFHHMGANHRLGATDFSNLDSQARIAHVAYLLLLPALEQEDRQWQTCG
ARALADLQRQGFAVSLDLVSAPETERYQRWVKPVLPYVDYLIINDQEARRLCQRPGDDDYIAQARSLLQMGVRKLVCIHF
PQGAVAIDAEGKTYKADAYHVPSHEVVSTLGAGDAFCAGMLYGIHEEWPLADALRLGCACAHFNLFSLSATEGARTLSEL
HDFIQHEESQI
>Mature_331_residues
MHKRRGIIAIGNLIVDQSLRCTEYPQESMLTQITHVDKSCGGGCTNVLFGLSRIDPSLPLALSGVIGRDTYGDFILQETA
RHNVSTSRVHVSAQDVTSFTYVMVNSQNGNRTFFHHMGANHRLGATDFSNLDSQARIAHVAYLLLLPALEQEDRQWQTCG
ARALADLQRQGFAVSLDLVSAPETERYQRWVKPVLPYVDYLIINDQEARRLCQRPGDDDYIAQARSLLQMGVRKLVCIHF
PQGAVAIDAEGKTYKADAYHVPSHEVVSTLGAGDAFCAGMLYGIHEEWPLADALRLGCACAHFNLFSLSATEGARTLSEL
HDFIQHEESQI

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI5670342, Length=303, Percent_Identity=26.4026402640264, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4557693, Length=303, Percent_Identity=25.0825082508251, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87081971, Length=340, Percent_Identity=26.1764705882353, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 36714; Mature: 36714

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKRRGIIAIGNLIVDQSLRCTEYPQESMLTQITHVDKSCGGGCTNVLFGLSRIDPSLPL
CCCCCCEEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCE
ALSGVIGRDTYGDFILQETARHNVSTSRVHVSAQDVTSFTYVMVNSQNGNRTFFHHMGAN
EECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHCCEEEEEEEECCCCCEEEEEECCCC
HRLGATDFSNLDSQARIAHVAYLLLLPALEQEDRQWQTCGARALADLQRQGFAVSLDLVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECC
APETERYQRWVKPVLPYVDYLIINDQEARRLCQRPGDDDYIAQARSLLQMGVRKLVCIHF
CCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEC
PQGAVAIDAEGKTYKADAYHVPSHEVVSTLGAGDAFCAGMLYGIHEEWPLADALRLGCAC
CCCCEEEECCCCEEECCCEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
AHFNLFSLSATEGARTLSELHDFIQHEESQI
HCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHKRRGIIAIGNLIVDQSLRCTEYPQESMLTQITHVDKSCGGGCTNVLFGLSRIDPSLPL
CCCCCCEEEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCE
ALSGVIGRDTYGDFILQETARHNVSTSRVHVSAQDVTSFTYVMVNSQNGNRTFFHHMGAN
EECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHCCEEEEEEEECCCCCEEEEEECCCC
HRLGATDFSNLDSQARIAHVAYLLLLPALEQEDRQWQTCGARALADLQRQGFAVSLDLVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEECC
APETERYQRWVKPVLPYVDYLIINDQEARRLCQRPGDDDYIAQARSLLQMGVRKLVCIHF
CCCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEC
PQGAVAIDAEGKTYKADAYHVPSHEVVSTLGAGDAFCAGMLYGIHEEWPLADALRLGCAC
CCCCEEEECCCCEEECCCEECCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
AHFNLFSLSATEGARTLSELHDFIQHEESQI
HCCEEEEEECCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA