Click here to switch to the map view.

The map label for this gene is rlmA [H]

Identifier: 238919618

GI number: 238919618

Start: 1673136

End: 1673939

Strand: Direct

Name: rlmA [H]

Synonym: NT01EI_1717

Alternate gene names: 238919618

Gene position: 1673136-1673939 (Clockwise)

Preceding gene: 238919617

Following gene: 238919623

Centisome position: 43.89

GC content: 60.32

Gene sequence:

>804_bases
ATGCCGTACCAATGTCCCCTGTGCCACTCTCCGCTGCACCAGGATGCACGCCAGTGGCGCTGCGTTAATAACCATCGATT
TGACTGCGCTAAAGAGGGCTATGTCAACCTGATGCCGGTGCAGTTTAAGCATTCGCGTCAGCCAGGTGACAGCAGCGAGA
TGATGCAGGCCCGCCGAGCCTTTTTGCAGGCTGACCATTATTTGCCGCTGCGTGACGCCGTACAGGGCCTTCTGGCACGC
TATTTGCCTAGTGACGGCTGTAACGTCCTGGATATCGGCTGTGGAGAAGGGTATTACACCGCCAGCTGGGCTAGCGTACG
GGAGGCGCAGGTCTATGGGCTGGATATCGCCAAGGTGGCCATTCGCTATGCGGCGCGGCGCTATCCGCAGGCTCACTTCT
GCGTTGCGTCGAGTCTGCGGCTGCCATTTGCCGATGCCAGCATCGGCGGTGCGGTACGCATCTACGCGCCATGCAATGCG
CAGGAGTTGGCTCGAGTGGTGGCGACAGGCGGTTGTCTGGTGACCGTTACGCCGGCGGAGCGCCATTTGTATCAGCTGAA
AGCGTTGGTCTACCCTGCAGTACATCTACATATGCAGAAGGCGGAGTTACTCTCGGGCTTTACCCTGCTTGAGAGCCAGC
GCCTGGGCTATGCCATGGCGCTGAACGGTGTCGAGGCGGCCGAGTTGCTGCAGATGACCCCTTTTGCCTGGCGGGCTCCG
CAGGGGGTTGCTGAGGCGCTGCAGGCGCGTGAGGCGTTTGAGTGTGAGACTGACTTTCTGATCCGGGTTTACCGCCGCGA
CTGA

Upstream 100 bases:

>100_bases
CGGCTTGCGCATGCCGCCGTCGCCCCCGATAATACCCGTCCTGTGTTGCGCTCGTCCCCATCACCGGCGGCGCTGTTCCT
CCAAAATAAGAGTAAACGCC

Downstream 100 bases:

>100_bases
GGCGGCGGAAAGGGGAGCAGGCGCGGCCTCCCTTACGCTGGCTTTTGCTGGTGCTCCAGCAGGAACTTAAAGATCTCGTC
CAGTGAGTCCAGGTTGGCCA

Product: ribosomal RNA large subunit methyltransferase A (1)

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPYQCPLCHSPLHQDARQWRCVNNHRFDCAKEGYVNLMPVQFKHSRQPGDSSEMMQARRAFLQADHYLPLRDAVQGLLAR
YLPSDGCNVLDIGCGEGYYTASWASVREAQVYGLDIAKVAIRYAARRYPQAHFCVASSLRLPFADASIGGAVRIYAPCNA
QELARVVATGGCLVTVTPAERHLYQLKALVYPAVHLHMQKAELLSGFTLLESQRLGYAMALNGVEAAELLQMTPFAWRAP
QGVAEALQAREAFECETDFLIRVYRRD

Sequences:

>Translated_267_residues
MPYQCPLCHSPLHQDARQWRCVNNHRFDCAKEGYVNLMPVQFKHSRQPGDSSEMMQARRAFLQADHYLPLRDAVQGLLAR
YLPSDGCNVLDIGCGEGYYTASWASVREAQVYGLDIAKVAIRYAARRYPQAHFCVASSLRLPFADASIGGAVRIYAPCNA
QELARVVATGGCLVTVTPAERHLYQLKALVYPAVHLHMQKAELLSGFTLLESQRLGYAMALNGVEAAELLQMTPFAWRAP
QGVAEALQAREAFECETDFLIRVYRRD
>Mature_266_residues
PYQCPLCHSPLHQDARQWRCVNNHRFDCAKEGYVNLMPVQFKHSRQPGDSSEMMQARRAFLQADHYLPLRDAVQGLLARY
LPSDGCNVLDIGCGEGYYTASWASVREAQVYGLDIAKVAIRYAARRYPQAHFCVASSLRLPFADASIGGAVRIYAPCNAQ
ELARVVATGGCLVTVTPAERHLYQLKALVYPAVHLHMQKAELLSGFTLLESQRLGYAMALNGVEAAELLQMTPFAWRAPQ
GVAEALQAREAFECETDFLIRVYRRD

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=267, Percent_Identity=58.0524344569288, Blast_Score=315, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 29883; Mature: 29751

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYQCPLCHSPLHQDARQWRCVNNHRFDCAKEGYVNLMPVQFKHSRQPGDSSEMMQARRA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
FLQADHYLPLRDAVQGLLARYLPSDGCNVLDIGCGEGYYTASWASVREAQVYGLDIAKVA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECHHHHHHHHHHCCHHHHHHH
IRYAARRYPQAHFCVASSLRLPFADASIGGAVRIYAPCNAQELARVVATGGCLVTVTPAE
HHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEECCHH
RHLYQLKALVYPAVHLHMQKAELLSGFTLLESQRLGYAMALNGVEAAELLQMTPFAWRAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCC
QGVAEALQAREAFECETDFLIRVYRRD
HHHHHHHHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure 
PYQCPLCHSPLHQDARQWRCVNNHRFDCAKEGYVNLMPVQFKHSRQPGDSSEMMQARRA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
FLQADHYLPLRDAVQGLLARYLPSDGCNVLDIGCGEGYYTASWASVREAQVYGLDIAKVA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECHHHHHHHHHHCCHHHHHHH
IRYAARRYPQAHFCVASSLRLPFADASIGGAVRIYAPCNAQELARVVATGGCLVTVTPAE
HHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEECCHH
RHLYQLKALVYPAVHLHMQKAELLSGFTLLESQRLGYAMALNGVEAAELLQMTPFAWRAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCC
QGVAEALQAREAFECETDFLIRVYRRD
HHHHHHHHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]