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The map label for this gene is gapA [H]

Identifier: 238919545

GI number: 238919545

Start: 1603580

End: 1604575

Strand: Reverse

Name: gapA [H]

Synonym: NT01EI_1641

Alternate gene names: 238919545

Gene position: 1604575-1603580 (Counterclockwise)

Preceding gene: 238919548

Following gene: 238919544

Centisome position: 42.09

GC content: 53.11

Gene sequence:

>996_bases
ATGACTATCAAAGTAGGTATCAACGGTTTTGGTCGTATCGGCCGTATTGTTTTCCGTGCTGCTCAGGAACGTTCTGACAT
CGAAATCGTTGGCATCAACGATCTGCTGGATGCCAACTACATGGCATACATGCTGAAGTACGACTCTACTCACGGTCGTT
TCAACGGCACTGTTGAAGTGGAAGAGGGCCACCTGATCGTTAACGGTAAAAAAATCCGTGTTACCGCTGAAAGAGATCCG
GCTAACCTGAAGTGGAATGAAATCGGTGTTGACGTTGTTGCCGAGGCGACCGGTCTGTTCCTGACCGACGAAACCGCACG
TAAGCACATCGCCGCCGGCGCCAAGAAAGTCGTCATGACTGGCCCGTCCAAAGATGCTACCCCGATGTTCGTTATGGGCG
TAAACCACAAGAACTACGCTGGCCAGGCGATCGTTTCCAACGCATCCTGCACCACCAACTGCCTGGCTCCGCTGGCTAAA
GTCCTGAACGACAACTTCGGCATCGTTGAAGCACTGATGACCACCGTTCACGCAACCACTGCTACCCAGAAAACCGTTGA
TGGTCCGTCCATGAAGGATTGGCGTGGCGGCCGCGGTGCCAGCCAGAACATCATCCCGTCCTCCACCGGCGCAGCCAAAG
CCGTTGGCAAAGTAATCCCGGAGCTGAACGGCAAACTGACCGGCATGGCTTTCCGCGTTCCGACCCCGAACGTATCCGTT
GTTGATCTGACTGCACGCCTGGCCAAGCCAGCTACCTATCAGCAGATCTGTGAAGTGATGAAGGCCGCTTCTGAAGGCGA
AATGAAAGGCGTTCTGGGCTACACCGATGAAGCCGTCGTTTCTACCGATTTCAATGGCGAAGTATGCACCTCAGTGTTTG
ATGCCGACGCCGGTATCTCTCTGAATGACAACTTCGTGAAACTGGTTTCCTGGTATGACAACGAAACTGGCTACTCGAAT
AAAGTTCTGGATCTGATCGCGCACATCTCCAAATAA

Upstream 100 bases:

>100_bases
ACGTATAGCAACAATTGACACGATTCCGCTTGACGCTCCATAAGGTTTTTGTAATTTTACAGGCAACCTTTTATTCACTA
ACCAATAGCTGGTGGAATAT

Downstream 100 bases:

>100_bases
ATGCGCATTGTGATCCCGTGATAAAAGGGCGACACTCAGTGTCGCCCTTTTTATTTTGTGTCTGTGGCACCACCTTCACC
AAGGAGTCTTACCATGTCCC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH-A [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTIKVGINGFGRIGRIVFRAAQERSDIEIVGINDLLDANYMAYMLKYDSTHGRFNGTVEVEEGHLIVNGKKIRVTAERDP
ANLKWNEIGVDVVAEATGLFLTDETARKHIAAGAKKVVMTGPSKDATPMFVMGVNHKNYAGQAIVSNASCTTNCLAPLAK
VLNDNFGIVEALMTTVHATTATQKTVDGPSMKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV
VDLTARLAKPATYQQICEVMKAASEGEMKGVLGYTDEAVVSTDFNGEVCTSVFDADAGISLNDNFVKLVSWYDNETGYSN
KVLDLIAHISK

Sequences:

>Translated_331_residues
MTIKVGINGFGRIGRIVFRAAQERSDIEIVGINDLLDANYMAYMLKYDSTHGRFNGTVEVEEGHLIVNGKKIRVTAERDP
ANLKWNEIGVDVVAEATGLFLTDETARKHIAAGAKKVVMTGPSKDATPMFVMGVNHKNYAGQAIVSNASCTTNCLAPLAK
VLNDNFGIVEALMTTVHATTATQKTVDGPSMKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV
VDLTARLAKPATYQQICEVMKAASEGEMKGVLGYTDEAVVSTDFNGEVCTSVFDADAGISLNDNFVKLVSWYDNETGYSN
KVLDLIAHISK
>Mature_330_residues
TIKVGINGFGRIGRIVFRAAQERSDIEIVGINDLLDANYMAYMLKYDSTHGRFNGTVEVEEGHLIVNGKKIRVTAERDPA
NLKWNEIGVDVVAEATGLFLTDETARKHIAAGAKKVVMTGPSKDATPMFVMGVNHKNYAGQAIVSNASCTTNCLAPLAKV
LNDNFGIVEALMTTVHATTATQKTVDGPSMKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVV
DLTARLAKPATYQQICEVMKAASEGEMKGVLGYTDEAVVSTDFNGEVCTSVFDADAGISLNDNFVKLVSWYDNETGYSNK
VLDLIAHISK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=66.6666666666667, Blast_Score=457, Evalue=1e-129,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=62.1212121212121, Blast_Score=427, Evalue=1e-120,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=89.4259818731118, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=41.6413373860182, Blast_Score=260, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=65.5688622754491, Blast_Score=439, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=65.5688622754491, Blast_Score=439, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=64.3712574850299, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=63.7724550898204, Blast_Score=429, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=66.4652567975831, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=65.558912386707, Blast_Score=442, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=65.2567975830816, Blast_Score=441, Evalue=1e-125,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=67.0731707317073, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=67.0731707317073, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=66.4634146341463, Blast_Score=441, Evalue=1e-124,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=66.4634146341463, Blast_Score=441, Evalue=1e-124,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=64.4171779141104, Blast_Score=426, Evalue=1e-119,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35450; Mature: 35319

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRIVFRAAQERSDIEIVGINDLLDANYMAYMLKYDSTHGRFNGTVEV
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECHHHHCCCEEEEEEEECCCCCEECCEEEE
EEGHLIVNGKKIRVTAERDPANLKWNEIGVDVVAEATGLFLTDETARKHIAAGAKKVVMT
ECCEEEECCEEEEEEECCCCCCCEEHHCCCEEEECCCCEEEECHHHHHHHHCCCCEEEEE
GPSKDATPMFVMGVNHKNYAGQAIVSNASCTTNCLAPLAKVLNDNFGIVEALMTTVHATT
CCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
ATQKTVDGPSMKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDLTARLAKPATYQQICEVMKAASEGEMKGVLGYTDEAVVSTDFNGEVCTSVFDADAGIS
EEEHHHHCCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCHHHHHHHCCCCCCE
LNDNFVKLVSWYDNETGYSNKVLDLIAHISK
ECCCEEEEEEEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVGINGFGRIGRIVFRAAQERSDIEIVGINDLLDANYMAYMLKYDSTHGRFNGTVEV
EEEEECCCCHHHHHHHHHHHHCCCCEEEEECHHHHCCCEEEEEEEECCCCCEECCEEEE
EEGHLIVNGKKIRVTAERDPANLKWNEIGVDVVAEATGLFLTDETARKHIAAGAKKVVMT
ECCEEEECCEEEEEEECCCCCCCEEHHCCCEEEECCCCEEEECHHHHHHHHCCCCEEEEE
GPSKDATPMFVMGVNHKNYAGQAIVSNASCTTNCLAPLAKVLNDNFGIVEALMTTVHATT
CCCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
ATQKTVDGPSMKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEE
VDLTARLAKPATYQQICEVMKAASEGEMKGVLGYTDEAVVSTDFNGEVCTSVFDADAGIS
EEEHHHHCCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCHHHHHHHCCCCCCE
LNDNFVKLVSWYDNETGYSNKVLDLIAHISK
ECCCEEEEEEEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]