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The map label for this gene is minC

Identifier: 238919527

GI number: 238919527

Start: 1584161

End: 1584841

Strand: Reverse

Name: minC

Synonym: NT01EI_1623

Alternate gene names: 238919527

Gene position: 1584841-1584161 (Counterclockwise)

Preceding gene: 238919532

Following gene: 238919526

Centisome position: 41.57

GC content: 55.65

Gene sequence:

>681_bases
ATGTCACAAGCGCCAATAGAACTGAAAGGCAGCAGTTTTACACTCTCGGTTGTCCATTTGCATAATTCTCAACCAGAGGT
AATTCGCCCGGCATTAATCGCCAAAGTCGGTCAAGCGCCCGCGTTTTTGAAAAATGCGCCTGTTGTTATTAATATTACTG
ATGTGAATGGCAGTGTGGAATGGCATGAAATGCTACGCATGTTCAGTGCTGCAGGGCTGCACGTCATCGGCGTCAGCGGC
TGTCGCGACGAAACACAAAAACAGGCGGTACTGCATGCGGGATTACCGTTGCTCAGCGAAGGTAAAGGCGCGGTGAAGAA
GGCGCCCGTCGCCCCGGCCACTCCCGTCGCGGCGAAAACCAAAATCATCAGTACCCCGGTGCGGTCAGGCCAGCAGATTT
ATGCGCGCAGCGGCGATTTGATCGTCACCAGTCACGTCAGCGCCGGCGCAGAGCTAATCGCCGACGGTAATATACATGTC
TACGGCATAATGCGTGGGCGAGCGTTGGCCGGCGCCGCAGGCGACAGCGGCAGCCAGATCTTCTGCAGCCATCTCTCCGC
CGAGCTGGTATCCATCGCTGGTCAGTACTGGCTAAGCGATCAGATCCCGGAAAACTATTATGGGCAGGCCGCCCACCTCA
CCCTGAGCAGCGGCGCCCTTACTATCCAATCTTTATTCTAG

Upstream 100 bases:

>100_bases
TAGATATACAGCTGACTATAACATGCTTAGATACATCGGAATATCACGCGCGCCGTGGTTATTTCGGAGATTTCCCAGTT
GCTGAGCTGAGTAAGGATAG

Downstream 100 bases:

>100_bases
GCCCTTCTTCAAAAAGGATATTTTCATGGCACGCATTATTGTTGTTACATCGGGTAAAGGGGGCGTTGGCAAGACTACAT
CAAGCGCGGCCATCGCAACC

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSQAPIELKGSSFTLSVVHLHNSQPEVIRPALIAKVGQAPAFLKNAPVVINITDVNGSVEWHEMLRMFSAAGLHVIGVSG
CRDETQKQAVLHAGLPLLSEGKGAVKKAPVAPATPVAAKTKIISTPVRSGQQIYARSGDLIVTSHVSAGAELIADGNIHV
YGIMRGRALAGAAGDSGSQIFCSHLSAELVSIAGQYWLSDQIPENYYGQAAHLTLSSGALTIQSLF

Sequences:

>Translated_226_residues
MSQAPIELKGSSFTLSVVHLHNSQPEVIRPALIAKVGQAPAFLKNAPVVINITDVNGSVEWHEMLRMFSAAGLHVIGVSG
CRDETQKQAVLHAGLPLLSEGKGAVKKAPVAPATPVAAKTKIISTPVRSGQQIYARSGDLIVTSHVSAGAELIADGNIHV
YGIMRGRALAGAAGDSGSQIFCSHLSAELVSIAGQYWLSDQIPENYYGQAAHLTLSSGALTIQSLF
>Mature_225_residues
SQAPIELKGSSFTLSVVHLHNSQPEVIRPALIAKVGQAPAFLKNAPVVINITDVNGSVEWHEMLRMFSAAGLHVIGVSGC
RDETQKQAVLHAGLPLLSEGKGAVKKAPVAPATPVAAKTKIISTPVRSGQQIYARSGDLIVTSHVSAGAELIADGNIHVY
GIMRGRALAGAAGDSGSQIFCSHLSAELVSIAGQYWLSDQIPENYYGQAAHLTLSSGALTIQSLF

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=231, Percent_Identity=63.6363636363636, Blast_Score=287, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_EDWI9 (C5B9V6)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933042.1
- GeneID:   7961951
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1623
- OMA:   IFCTHLA
- ProtClustDB:   PRK03511
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 23653; Mature: 23522

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAPIELKGSSFTLSVVHLHNSQPEVIRPALIAKVGQAPAFLKNAPVVINITDVNGSVE
CCCCCEEECCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCHHHCCCCEEEEEEECCCCCH
WHEMLRMFSAAGLHVIGVSGCRDETQKQAVLHAGLPLLSEGKGAVKKAPVAPATPVAAKT
HHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHH
KIISTPVRSGQQIYARSGDLIVTSHVSAGAELIADGNIHVYGIMRGRALAGAAGDSGSQI
EEEECCCCCCCEEEECCCCEEEEECCCCCEEEEECCCEEEEEEEECCEEECCCCCCCCEE
FCSHLSAELVSIAGQYWLSDQIPENYYGQAAHLTLSSGALTIQSLF
EHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEECC
>Mature Secondary Structure 
SQAPIELKGSSFTLSVVHLHNSQPEVIRPALIAKVGQAPAFLKNAPVVINITDVNGSVE
CCCCEEECCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCHHHCCCCEEEEEEECCCCCH
WHEMLRMFSAAGLHVIGVSGCRDETQKQAVLHAGLPLLSEGKGAVKKAPVAPATPVAAKT
HHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHH
KIISTPVRSGQQIYARSGDLIVTSHVSAGAELIADGNIHVYGIMRGRALAGAAGDSGSQI
EEEECCCCCCCEEEECCCCEEEEECCCCCEEEEECCCEEEEEEEECCEEECCCCCCCCEE
FCSHLSAELVSIAGQYWLSDQIPENYYGQAAHLTLSSGALTIQSLF
EHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA