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The map label for this gene is tsr [H]

Identifier: 238919367

GI number: 238919367

Start: 1436212

End: 1437798

Strand: Direct

Name: tsr [H]

Synonym: NT01EI_1461

Alternate gene names: 238919367

Gene position: 1436212-1437798 (Clockwise)

Preceding gene: 238919365

Following gene: 238919368

Centisome position: 37.67

GC content: 59.48

Gene sequence:

>1587_bases
GTGTTCTTTGACGCCCTGAAAAGCGACAAAGAAAGTATGACCGTTTTACAAACCATTCGCCAACAGCAGGCCGCACTTAA
CGCCAGCTGGGTGGCATTGCTCCAGACGCGCAATACCTTAAACCGTGCCGGGATCCGCTATATGGCCGATCTGAACAAGA
CCGGCACCGGTTCGACGGTGACTGATTTGATGCAGCTTGCCCGAACGGAGCTGAAAACTGCGGAAGGTGAGTGGCAACGC
TATCAGGGATTGCCGCGCGATCCGCGTCAGAGCGAGGAAGCCATGGAGGCCATGGAGCAAAACTATGGCACCCTGCATAA
TGCGCTGGGAGAGCTGATCCAGCTGCTTTCCGCCGGCCACATCAATGAATTCTTCGAACAGCCGACCCAAAGTTATCAGA
ATAGCTTTGAGAAGAGCTATACAACCTACCTCGCTCAGAATGATCGCCTTTATAAAGGTGCAATGTCAGATAATAATGAC
GCTTATCACTCAGCCCTGTGGACACTGTTTGGCGTTATGGTGGTGGTTATCGCAGCCATCGTGCTGGTGTGGATGGGGAT
CTACCGTGCGCTGAGTCGTCCGCTCAATAGCCTGATGGGCAATATCCGCCAGTTTGCCGTCGGCGATCTCTCCGGTCGCA
TTGAGGTGCGCGGCAGCAATGAAATGGGACAGCTGGCCGACAGCCTGCGCCATATGCAGAGCGAATTTATCCGCACCGTC
AGCGACGTCCGTCAGGGCGCCAATGCCATCTACAGCGGCGCCAGCGAAATCTCTGCCGGAAATCACGATCTCTCCTCGCG
TACCGAACAACAGGCGGCATCGCTGGAAGAAACGGCGGCCAGCATGGAACAGCTGACGGCGACCGTGAAACAGAACGCCG
AAAACGCCCGCCAGGCCAGTCAGCTGGCGCTGAGCGCCTCTGAGACGGCCCAGCGCGGCGGCAAGGTCGTTGCCAACGTA
GTGCAGACCATGCATGACATCGCCGGCAGCTCGCAGAAGATCGCTGACATTACCGGGGTCATCGACGGCATCGCCTTCCA
GACCAATATTCTGGCGCTGAACGCGGCGGTAGAAGCGGCGCGCGCCGGTGAGCAGGGGCGTGGTTTTGCCGTGGTGGCGG
GCGAGGTGCGTAACCTGGCTCAGCGCAGCGCCCAGGCAGCGAAAGAGATTAAAGGGCTGATTGAGGACTCCGTCAGCAAG
GTCGATACCGGTTCGGTATTGGTCGAAAGCGCCGGCGATACCATGGGTGACATCGTTAACGCGGTCACCCGGGTCACCGA
CATCATGGGTGAGATTGCCTCGGCCTCTGACGAACAGAGCCGCGGTATCGAGCAGGTGGGCCAGGCCGTCTCCGAGATGG
ACAGGGTGACACAGCAGAACGCCGCACTGGTAGAAGAGTCCGCCTCTGCCGCCGCGTCGCTGGAGGATCAGGCCAGCCAT
CTGAATCAGGCTGTCGCGGTATTCCGCATTGAGCCTCAGGGCGAGGCGGAGCCGGTAGTCCGCACCGCGCCGCTCAGCAG
CGCCGCTCCCGCGCCGGTGAAAGCCAAAGCGTCGGACAGCAGCGACGATAACTGGGAGACGTTCTGA

Upstream 100 bases:

>100_bases
CAGCAAAAATGAGACGCCCATGTTAAACCGCATAAAAGTAGTTACCAGTTTGCTACTGGTGTTGGGGTTATTTGGCATTT
TGCAGATGACTTCCGGAGGA

Downstream 100 bases:

>100_bases
CCACCCGACGGCTTTCCGCCCCTGATGGCGGAGAGCTGACTGCCAGTGCCGGGCGCCGTGAGGCGCCATAGGCATATGGG
AGCCAACATAAAAATGACAA

Product: methyl-accepting chemotaxis protein I

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MFFDALKSDKESMTVLQTIRQQQAALNASWVALLQTRNTLNRAGIRYMADLNKTGTGSTVTDLMQLARTELKTAEGEWQR
YQGLPRDPRQSEEAMEAMEQNYGTLHNALGELIQLLSAGHINEFFEQPTQSYQNSFEKSYTTYLAQNDRLYKGAMSDNND
AYHSALWTLFGVMVVVIAAIVLVWMGIYRALSRPLNSLMGNIRQFAVGDLSGRIEVRGSNEMGQLADSLRHMQSEFIRTV
SDVRQGANAIYSGASEISAGNHDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASQLALSASETAQRGGKVVANV
VQTMHDIAGSSQKIADITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKGLIEDSVSK
VDTGSVLVESAGDTMGDIVNAVTRVTDIMGEIASASDEQSRGIEQVGQAVSEMDRVTQQNAALVEESASAAASLEDQASH
LNQAVAVFRIEPQGEAEPVVRTAPLSSAAPAPVKAKASDSSDDNWETF

Sequences:

>Translated_528_residues
MFFDALKSDKESMTVLQTIRQQQAALNASWVALLQTRNTLNRAGIRYMADLNKTGTGSTVTDLMQLARTELKTAEGEWQR
YQGLPRDPRQSEEAMEAMEQNYGTLHNALGELIQLLSAGHINEFFEQPTQSYQNSFEKSYTTYLAQNDRLYKGAMSDNND
AYHSALWTLFGVMVVVIAAIVLVWMGIYRALSRPLNSLMGNIRQFAVGDLSGRIEVRGSNEMGQLADSLRHMQSEFIRTV
SDVRQGANAIYSGASEISAGNHDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASQLALSASETAQRGGKVVANV
VQTMHDIAGSSQKIADITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKGLIEDSVSK
VDTGSVLVESAGDTMGDIVNAVTRVTDIMGEIASASDEQSRGIEQVGQAVSEMDRVTQQNAALVEESASAAASLEDQASH
LNQAVAVFRIEPQGEAEPVVRTAPLSSAAPAPVKAKASDSSDDNWETF
>Mature_528_residues
MFFDALKSDKESMTVLQTIRQQQAALNASWVALLQTRNTLNRAGIRYMADLNKTGTGSTVTDLMQLARTELKTAEGEWQR
YQGLPRDPRQSEEAMEAMEQNYGTLHNALGELIQLLSAGHINEFFEQPTQSYQNSFEKSYTTYLAQNDRLYKGAMSDNND
AYHSALWTLFGVMVVVIAAIVLVWMGIYRALSRPLNSLMGNIRQFAVGDLSGRIEVRGSNEMGQLADSLRHMQSEFIRTV
SDVRQGANAIYSGASEISAGNHDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASQLALSASETAQRGGKVVANV
VQTMHDIAGSSQKIADITGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKGLIEDSVSK
VDTGSVLVESAGDTMGDIVNAVTRVTDIMGEIASASDEQSRGIEQVGQAVSEMDRVTQQNAALVEESASAAASLEDQASH
LNQAVAVFRIEPQGEAEPVVRTAPLSSAAPAPVKAKASDSSDDNWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=529, Percent_Identity=72.9678638941399, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1788195, Length=529, Percent_Identity=55.765595463138, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1788194, Length=498, Percent_Identity=48.5943775100402, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1787690, Length=446, Percent_Identity=49.5515695067265, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1789453, Length=321, Percent_Identity=40.4984423676012, Blast_Score=227, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56818; Mature: 56818

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFDALKSDKESMTVLQTIRQQQAALNASWVALLQTRNTLNRAGIRYMADLNKTGTGSTV
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
TDLMQLARTELKTAEGEWQRYQGLPRDPRQSEEAMEAMEQNYGTLHNALGELIQLLSAGH
HHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INEFFEQPTQSYQNSFEKSYTTYLAQNDRLYKGAMSDNNDAYHSALWTLFGVMVVVIAAI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVWMGIYRALSRPLNSLMGNIRQFAVGDLSGRIEVRGSNEMGQLADSLRHMQSEFIRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
SDVRQGANAIYSGASEISAGNHDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQAS
HHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLALSASETAQRGGKVVANVVQTMHDIAGSSQKIADITGVIDGIAFQTNILALNAAVEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKGLIEDSVSKVDTGSVLVESAGDTMGDIVN
HCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHH
AVTRVTDIMGEIASASDEQSRGIEQVGQAVSEMDRVTQQNAALVEESASAAASLEDQASH
HHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQAVAVFRIEPQGEAEPVVRTAPLSSAAPAPVKAKASDSSDDNWETF
HHHHHHEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFFDALKSDKESMTVLQTIRQQQAALNASWVALLQTRNTLNRAGIRYMADLNKTGTGSTV
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
TDLMQLARTELKTAEGEWQRYQGLPRDPRQSEEAMEAMEQNYGTLHNALGELIQLLSAGH
HHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INEFFEQPTQSYQNSFEKSYTTYLAQNDRLYKGAMSDNNDAYHSALWTLFGVMVVVIAAI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
VLVWMGIYRALSRPLNSLMGNIRQFAVGDLSGRIEVRGSNEMGQLADSLRHMQSEFIRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
SDVRQGANAIYSGASEISAGNHDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQAS
HHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLALSASETAQRGGKVVANVVQTMHDIAGSSQKIADITGVIDGIAFQTNILALNAAVEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKGLIEDSVSKVDTGSVLVESAGDTMGDIVN
HCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHH
AVTRVTDIMGEIASASDEQSRGIEQVGQAVSEMDRVTQQNAALVEESASAAASLEDQASH
HHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNQAVAVFRIEPQGEAEPVVRTAPLSSAAPAPVKAKASDSSDDNWETF
HHHHHHEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]