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The map label for this gene is cheA [H]

Identifier: 238919364

GI number: 238919364

Start: 1433250

End: 1435388

Strand: Direct

Name: cheA [H]

Synonym: NT01EI_1458

Alternate gene names: 238919364

Gene position: 1433250-1435388 (Clockwise)

Preceding gene: 238919362

Following gene: 238919365

Centisome position: 37.6

GC content: 61.06

Gene sequence:

>2139_bases
ATGGATATGAGTGCGTTTTATCAAACGTTCTTTGATGAAGCGGATGAACTGTTGGCTGATATGGAACAGCACCTGCTGGC
GCTGGATCCCCAGGAGCCGGATAACGAACAACTGAACGCTATCTTTCGCGCTGCCCACTCTATCAAGGGGGGGGCGGCCA
CTTTCGGTTTTACCGTACTGCAGGAGACCACGCATCTGCTGGAAAACCTGCTCGACGGTGCCCGCCGTGGTGAAATGCGG
CTGAGTACCGAAATCATCAACCTGTTTCTGGAAACCAAAGATATTATGCAGGATCAGCTCGATGCCTATAAGTCCGCGCA
GGACCCCGATGCCGATAGCTTTGAGTATATCTGTCAGGCGCTGAGGCAGCTGGCGCAGGAAGCCAAAGGGGAGGCTCCTG
TCGCGGCTCCGGCAAGCGTTGTGGCAGAGACGGTCAGCGCTCCCGCAGCCCCGGCTGCAGCCCCCGCCGCGGCCGCGGCC
CCGGCAACCGGAGCCATGACGGTCTCCCTGACCGGGCTCAAGCCGGCCGAAATCCCGCTGATGCTGGAGGAGCTGGGGAA
TCTGGGTACCGTACAGCAGCATCAGGAGAGCGACAGTTCGCTGGAGGTGGTACTGGATACCACGGTCAGTGAGGATGATA
TTACGGCGGTGCTGTGCTTTGTGCTGGAGCCGGAGCAGATCCACTTTACCCATCCGACGGCGGAGGTAGCGCCGCAGGTC
AGCCTGGAAGAGGCAGCCCTGTCATCTGATGCGGTGACCACCGAGACTTCCGTGGTGGAGCCTGCCCCGGTTTCTGCGGC
CGCAGAGGCCACCGTGGCCCCGGCCGGAACCACACCGGCCCAAGCTGAAACCACACCAGCCGCTGCGACTCCTGCTGAGG
CTGGCGCAGCATCTGCCGCGCCAGCCCCGCATATCCCGCGTCACAACCCCCGCGCGGCCAAAGGGGCAGAGAGCAGCACC
AGCATTCGCGTCGCCGTGGAGAAGGTCGATCAGCTGATCAATCTGGTGGGCGAACTGGTGATCACCCAGTCGATGCTGGC
GCAGCGTTCCAATATGCTGGATCCGGTCGATCACGGCGATCTGCTCAATAGCCTGGGCCAGCTTGAGCGCAACGCCCGGG
ATCTGCAGGAGTCGGTCATGTCGATCCGCATGATGCCGATGGAGTACGTCTTCAGCCGTTTCCCGCGTCTGGTGCGTGAT
CTGGCCAGCAAGCTCGACAAGCAGGTAGAGCTGACCCTGCTGGGCAGCTCCACCGAACTGGATAAGAGCCTGATCGAGCG
CATTATCGATCCGCTGACTCACCTGGTGCGCAACAGTCTGGACCACGGCATCGAATCGCCGCAGGTACGCCAGGCGGCGG
GTAAGAGCGCCGTCGGTAACCTGACTCTCTCTGCGGAACACCAGGGGGGCAATATCTATATTGAGGTCATCGACGATGGC
GCCGGGCTGAATCACCAGAAGATCCTGGATAAAGCGCGTTCCCAGGGGATGGCGATACACGACAACATGACCGACGAAGA
GATTGGCCTGCTGATCTTTGCGCCGGGTTTCTCCACCGCCGATAAAGTAACCGATGTTTCCGGACGCGGCGTCGGGATGG
ATGTGGTGAAGCGAAACATTCAGGCGATGGGCGGCCACGTTGAGATCGAATCGCGTGAAGGGAAAGGTACGACGATCCGT
ATCGTCCTGCCGCTGACCCTGGCGATTCTGGACGGTATGTCGGTCAAAGTCAGCGGCGAGGTTTTCATTCTGCCACTGAA
CGCCGTGATGGAGTCACTGCAGCCAAGCGACGATGATCTCTACCCGCTGGCCGGTGGTGAGCGGGTGTTGCAGGTGCGCG
GCGAATATTTGCCGCTGGTGGAGCTGCATCGCGTCTTTGACGTCGCCGATGCCAAGACCGACGCCACTCAGGGGATTGTG
GTGATCCTGCAAAGCGCCGGACGCCGCTATGCGCTGTTGGTCGATCAGCTGATCGGCCAGCATCAGGTGGTGGTGAAAAA
CCTGGAAACCAACTACCGCAAAGTGCCGGGTATTTCCGCGGCAACCATCCTCGGCGACGGCAGCGTGGCGCTGATCGTCG
ACGTGGCGGCGCTGCAGGGCATCAACCGGGAAAAACGGGTCTCCGGCACGGCCGCCTGA

Upstream 100 bases:

>100_bases
ACCGGCGGTAACACCCTTGATTCCGACTCCGACGCCGATGGCGCCAATGAACGACCACGTCAAAATTCCGAGCGCGATAG
ATAAGAGGTGACCTGTGAGC

Downstream 100 bases:

>100_bases
CTCTTAACCATGCAACCGGCGCCGCCGTAGGCGGCGCTGATGACGATGAATAAATAAAGGTGAACTGACATGACTGGACT
GGCTTCCGTAGACAAACTGG

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MDMSAFYQTFFDEADELLADMEQHLLALDPQEPDNEQLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRGEMR
LSTEIINLFLETKDIMQDQLDAYKSAQDPDADSFEYICQALRQLAQEAKGEAPVAAPASVVAETVSAPAAPAAAPAAAAA
PATGAMTVSLTGLKPAEIPLMLEELGNLGTVQQHQESDSSLEVVLDTTVSEDDITAVLCFVLEPEQIHFTHPTAEVAPQV
SLEEAALSSDAVTTETSVVEPAPVSAAAEATVAPAGTTPAQAETTPAAATPAEAGAASAAPAPHIPRHNPRAAKGAESST
SIRVAVEKVDQLINLVGELVITQSMLAQRSNMLDPVDHGDLLNSLGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRD
LASKLDKQVELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIESPQVRQAAGKSAVGNLTLSAEHQGGNIYIEVIDDG
AGLNHQKILDKARSQGMAIHDNMTDEEIGLLIFAPGFSTADKVTDVSGRGVGMDVVKRNIQAMGGHVEIESREGKGTTIR
IVLPLTLAILDGMSVKVSGEVFILPLNAVMESLQPSDDDLYPLAGGERVLQVRGEYLPLVELHRVFDVADAKTDATQGIV
VILQSAGRRYALLVDQLIGQHQVVVKNLETNYRKVPGISAATILGDGSVALIVDVAALQGINREKRVSGTAA

Sequences:

>Translated_712_residues
MDMSAFYQTFFDEADELLADMEQHLLALDPQEPDNEQLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRGEMR
LSTEIINLFLETKDIMQDQLDAYKSAQDPDADSFEYICQALRQLAQEAKGEAPVAAPASVVAETVSAPAAPAAAPAAAAA
PATGAMTVSLTGLKPAEIPLMLEELGNLGTVQQHQESDSSLEVVLDTTVSEDDITAVLCFVLEPEQIHFTHPTAEVAPQV
SLEEAALSSDAVTTETSVVEPAPVSAAAEATVAPAGTTPAQAETTPAAATPAEAGAASAAPAPHIPRHNPRAAKGAESST
SIRVAVEKVDQLINLVGELVITQSMLAQRSNMLDPVDHGDLLNSLGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRD
LASKLDKQVELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIESPQVRQAAGKSAVGNLTLSAEHQGGNIYIEVIDDG
AGLNHQKILDKARSQGMAIHDNMTDEEIGLLIFAPGFSTADKVTDVSGRGVGMDVVKRNIQAMGGHVEIESREGKGTTIR
IVLPLTLAILDGMSVKVSGEVFILPLNAVMESLQPSDDDLYPLAGGERVLQVRGEYLPLVELHRVFDVADAKTDATQGIV
VILQSAGRRYALLVDQLIGQHQVVVKNLETNYRKVPGISAATILGDGSVALIVDVAALQGINREKRVSGTAA
>Mature_712_residues
MDMSAFYQTFFDEADELLADMEQHLLALDPQEPDNEQLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRGEMR
LSTEIINLFLETKDIMQDQLDAYKSAQDPDADSFEYICQALRQLAQEAKGEAPVAAPASVVAETVSAPAAPAAAPAAAAA
PATGAMTVSLTGLKPAEIPLMLEELGNLGTVQQHQESDSSLEVVLDTTVSEDDITAVLCFVLEPEQIHFTHPTAEVAPQV
SLEEAALSSDAVTTETSVVEPAPVSAAAEATVAPAGTTPAQAETTPAAATPAEAGAASAAPAPHIPRHNPRAAKGAESST
SIRVAVEKVDQLINLVGELVITQSMLAQRSNMLDPVDHGDLLNSLGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRD
LASKLDKQVELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIESPQVRQAAGKSAVGNLTLSAEHQGGNIYIEVIDDG
AGLNHQKILDKARSQGMAIHDNMTDEEIGLLIFAPGFSTADKVTDVSGRGVGMDVVKRNIQAMGGHVEIESREGKGTTIR
IVLPLTLAILDGMSVKVSGEVFILPLNAVMESLQPSDDDLYPLAGGERVLQVRGEYLPLVELHRVFDVADAKTDATQGIV
VILQSAGRRYALLVDQLIGQHQVVVKNLETNYRKVPGISAATILGDGSVALIVDVAALQGINREKRVSGTAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=712, Percent_Identity=68.5393258426966, Blast_Score=946, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75814; Mature: 75814

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMSAFYQTFFDEADELLADMEQHLLALDPQEPDNEQLNAIFRAAHSIKGGAATFGFTVL
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
QETTHLLENLLDGARRGEMRLSTEIINLFLETKDIMQDQLDAYKSAQDPDADSFEYICQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LRQLAQEAKGEAPVAAPASVVAETVSAPAAPAAAPAAAAAPATGAMTVSLTGLKPAEIPL
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCEEEEEEECCCCCCCHH
MLEELGNLGTVQQHQESDSSLEVVLDTTVSEDDITAVLCFVLEPEQIHFTHPTAEVAPQV
HHHHCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHEEEEEEECCCEEEEECCHHHHCCCC
SLEEAALSSDAVTTETSVVEPAPVSAAAEATVAPAGTTPAQAETTPAAATPAEAGAASAA
CHHHHHCCCCCCCCCCCCCCCCCCCHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAPHIPRHNPRAAKGAESSTSIRVAVEKVDQLINLVGELVITQSMLAQRSNMLDPVDHGD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LLNSLGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRDLASKLDKQVELTLLGSSTEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
DKSLIERIIDPLTHLVRNSLDHGIESPQVRQAAGKSAVGNLTLSAEHQGGNIYIEVIDDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECC
AGLNHQKILDKARSQGMAIHDNMTDEEIGLLIFAPGFSTADKVTDVSGRGVGMDVVKRNI
CCCCHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCHHHHHHHH
QAMGGHVEIESREGKGTTIRIVLPLTLAILDGMSVKVSGEVFILPLNAVMESLQPSDDDL
HHCCCEEEEECCCCCCCEEEEEHHHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCCCCE
YPLAGGERVLQVRGEYLPLVELHRVFDVADAKTDATQGIVVILQSAGRRYALLVDQLIGQ
EECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCC
HQVVVKNLETNYRKVPGISAATILGDGSVALIVDVAALQGINREKRVSGTAA
HHHHHHHHCCCHHCCCCCCEEEEECCCCEEEEEEHHHHHCCCHHHCCCCCCC
>Mature Secondary Structure
MDMSAFYQTFFDEADELLADMEQHLLALDPQEPDNEQLNAIFRAAHSIKGGAATFGFTVL
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
QETTHLLENLLDGARRGEMRLSTEIINLFLETKDIMQDQLDAYKSAQDPDADSFEYICQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LRQLAQEAKGEAPVAAPASVVAETVSAPAAPAAAPAAAAAPATGAMTVSLTGLKPAEIPL
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCEEEEEEECCCCCCCHH
MLEELGNLGTVQQHQESDSSLEVVLDTTVSEDDITAVLCFVLEPEQIHFTHPTAEVAPQV
HHHHCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHEEEEEEECCCEEEEECCHHHHCCCC
SLEEAALSSDAVTTETSVVEPAPVSAAAEATVAPAGTTPAQAETTPAAATPAEAGAASAA
CHHHHHCCCCCCCCCCCCCCCCCCCHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAPHIPRHNPRAAKGAESSTSIRVAVEKVDQLINLVGELVITQSMLAQRSNMLDPVDHGD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LLNSLGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRDLASKLDKQVELTLLGSSTEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
DKSLIERIIDPLTHLVRNSLDHGIESPQVRQAAGKSAVGNLTLSAEHQGGNIYIEVIDDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECC
AGLNHQKILDKARSQGMAIHDNMTDEEIGLLIFAPGFSTADKVTDVSGRGVGMDVVKRNI
CCCCHHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCHHHHHHHH
QAMGGHVEIESREGKGTTIRIVLPLTLAILDGMSVKVSGEVFILPLNAVMESLQPSDDDL
HHCCCEEEEECCCCCCCEEEEEHHHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCCCCE
YPLAGGERVLQVRGEYLPLVELHRVFDVADAKTDATQGIVVILQSAGRRYALLVDQLIGQ
EECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCC
HQVVVKNLETNYRKVPGISAATILGDGSVALIVDVAALQGINREKRVSGTAA
HHHHHHHHCCCHHCCCCCCEEEEECCCCEEEEEEHHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]