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The map label for this gene is arnT

Identifier: 238919326

GI number: 238919326

Start: 1405080

End: 1406738

Strand: Direct

Name: arnT

Synonym: NT01EI_1417

Alternate gene names: 238919326

Gene position: 1405080-1406738 (Clockwise)

Preceding gene: 238919325

Following gene: 238919327

Centisome position: 36.86

GC content: 60.76

Gene sequence:

>1659_bases
ATGAAGAAGATCGCAGGATGGTTTACGCTGGCTGTACTGTTTGTCCTTTATTACATCGTTCCGCTGCCGGGACGTTTATT
ATGGCAGCCGGATGAAACCCGCTATGCCGAAATCAGCCGCGAGATGCTGGCCAGTGGAGACTGGATCGTACCGCACTTCC
TCGGCCTGCGCTATTTTGAAAAGCCGGTGGCCGGTTATTGGGTGAATAATCTGGGGCAGTGGCTGTTTGGCGACGGCAAC
TTTGCTGTCCGCTTTGGCGCTGTGCTGGCGACGGTATTGAGTGCGCTGCTGGTGTTCTGGCTGGCGCGTCGGTTACTGTC
TGGCCCCCGCCCGGCTGTTGTGGCTGTACTGATTTACCTGACCAGTTTTCTGGTCTACGGCGTTGGCAGCTATGCGGTGT
TGGACCCGATCTTTACCCTGTGGATGACCGCGGCCATGTGCAGCTTCTGGTTGGGTGAGCAGGCCAGCAGTGCGCGGGGC
AAGGCTGGTGGCTACATTTTGCTGGGGTTGGCCTGCGGTATGGGCTTTATGACCAAAGGGTTCCTGGCGCTGGCGATCCC
GGTGATTGCCGTCCTGCCCTGGGTGATCGCCCAACGGCGCTGGAAATCCCTGTTCTGCTTTGGTCCGCTGGCGGTATTGA
GCGCCATTCTCATCAGCCTGCCGTGGGTGCTGGCGATCGCACAGCACGAGCCGGACTATTGGCGCTACTTCTTCTGGGTG
GAGCATATTCAGCGCTTTGCCGAAGATAACGCCCAGCATAAGGCGCCGTTCTGGTATTACCTGCCGATCCTCCTCATCGG
CCTGCTGCCCTGGCTGGGGCTGCTGCCCGGCGCGCTGCGGGAAGGGTGGCGGGGCCGGGTCAGTCAGGGCGGGGATTTTT
ACCTGCTCGGCTGGGCGGTAATGCCATTTTTACTGTTCAGCATCGCCAAAGGAAAGCTGCCGACCTATATTTTGCCCTGC
TTTGCGCCGCTGGCGATCCTGATGGCGGGCTATGTACAGCGTCTGACCGGAGAGAATGGCAAGGCACTGCGGATCAACGG
GTTGATTAACCTGCTGGTCGGCCTGGGCGGCATGGCGGCGATCCTGCTGGTGCTGGCGCCCTGGGGCATCACGGGACACC
CGCTGTTCGGCGCACATGAGATCGGTAAAGTGATCCTGGGCACCATCGCTTTTGGCGTATGGGCGCTGTTTGGCGCACTG
TCGCTGTATCATTCACGCCGCTACTGGCGCTGGAGCGCCGCCTGCCTGCTGGGGGTCGCCCTGCTGATCGGTACGGCGCT
GCCACAGCAGGTCATGGAGTCCAAGCAGCCGCAGGCGCTGATCCAGGCGGCGATGCCGCAGCTGCAGGCGAGCCGCTATA
TTCTGAGTGACAGCGTCGGTGTCGCCGCGGGGCTGGCCTGGGAGCTCAAGCGCAGTGATATCTATATGTATGATAAAACT
GGCGAGCTTCAGTATGGGCTGAGCTACCCGGATGCCGCGGGTCACCTGGTCAAGGCAGAGCAGTTCCCGGCCTGGCTGGC
GGAGCACCGGAAACAGGGGGCGATTTCCCTGGTATTACTGCTGCCGCGCGACGGACAGATTAACCCGGCGCTGCCGTCGG
CGGATATGACTTTGCGTAAAGGGCGTTTCCTGCTGTTACAGTATCAGCAGCAGCCATGA

Upstream 100 bases:

>100_bases
TGCCAGATGATATTACGCTGTTGCCGTGCGGGAGAGTCGTTCGCGCGACGCTGAGCGGGCGTGAGGGATGGCTGGGTTGT
CAGCAGGAGATGGAGTCACC

Downstream 100 bases:

>100_bases
GCTATCTGCTGATCATGTTATCCAGCCTGCTCAGCTGCGCAGGACAGCTGTGCCAGAAACAGGCTATGTGCGGTGTGCCC
CGCGGCTCACCGCGCCGCCA

Product: 4-amino-4-deoxy-L-arabinose transferase

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKKIAGWFTLAVLFVLYYIVPLPGRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPVAGYWVNNLGQWLFGDGN
FAVRFGAVLATVLSALLVFWLARRLLSGPRPAVVAVLIYLTSFLVYGVGSYAVLDPIFTLWMTAAMCSFWLGEQASSARG
KAGGYILLGLACGMGFMTKGFLALAIPVIAVLPWVIAQRRWKSLFCFGPLAVLSAILISLPWVLAIAQHEPDYWRYFFWV
EHIQRFAEDNAQHKAPFWYYLPILLIGLLPWLGLLPGALREGWRGRVSQGGDFYLLGWAVMPFLLFSIAKGKLPTYILPC
FAPLAILMAGYVQRLTGENGKALRINGLINLLVGLGGMAAILLVLAPWGITGHPLFGAHEIGKVILGTIAFGVWALFGAL
SLYHSRRYWRWSAACLLGVALLIGTALPQQVMESKQPQALIQAAMPQLQASRYILSDSVGVAAGLAWELKRSDIYMYDKT
GELQYGLSYPDAAGHLVKAEQFPAWLAEHRKQGAISLVLLLPRDGQINPALPSADMTLRKGRFLLLQYQQQP

Sequences:

>Translated_552_residues
MKKIAGWFTLAVLFVLYYIVPLPGRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPVAGYWVNNLGQWLFGDGN
FAVRFGAVLATVLSALLVFWLARRLLSGPRPAVVAVLIYLTSFLVYGVGSYAVLDPIFTLWMTAAMCSFWLGEQASSARG
KAGGYILLGLACGMGFMTKGFLALAIPVIAVLPWVIAQRRWKSLFCFGPLAVLSAILISLPWVLAIAQHEPDYWRYFFWV
EHIQRFAEDNAQHKAPFWYYLPILLIGLLPWLGLLPGALREGWRGRVSQGGDFYLLGWAVMPFLLFSIAKGKLPTYILPC
FAPLAILMAGYVQRLTGENGKALRINGLINLLVGLGGMAAILLVLAPWGITGHPLFGAHEIGKVILGTIAFGVWALFGAL
SLYHSRRYWRWSAACLLGVALLIGTALPQQVMESKQPQALIQAAMPQLQASRYILSDSVGVAAGLAWELKRSDIYMYDKT
GELQYGLSYPDAAGHLVKAEQFPAWLAEHRKQGAISLVLLLPRDGQINPALPSADMTLRKGRFLLLQYQQQP
>Mature_552_residues
MKKIAGWFTLAVLFVLYYIVPLPGRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPVAGYWVNNLGQWLFGDGN
FAVRFGAVLATVLSALLVFWLARRLLSGPRPAVVAVLIYLTSFLVYGVGSYAVLDPIFTLWMTAAMCSFWLGEQASSARG
KAGGYILLGLACGMGFMTKGFLALAIPVIAVLPWVIAQRRWKSLFCFGPLAVLSAILISLPWVLAIAQHEPDYWRYFFWV
EHIQRFAEDNAQHKAPFWYYLPILLIGLLPWLGLLPGALREGWRGRVSQGGDFYLLGWAVMPFLLFSIAKGKLPTYILPC
FAPLAILMAGYVQRLTGENGKALRINGLINLLVGLGGMAAILLVLAPWGITGHPLFGAHEIGKVILGTIAFGVWALFGAL
SLYHSRRYWRWSAACLLGVALLIGTALPQQVMESKQPQALIQAAMPQLQASRYILSDSVGVAAGLAWELKRSDIYMYDKT
GELQYGLSYPDAAGHLVKAEQFPAWLAEHRKQGAISLVLLLPRDGQINPALPSADMTLRKGRFLLLQYQQQP

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family

Homologues:

Organism=Escherichia coli, GI1788591, Length=552, Percent_Identity=56.3405797101449, Blast_Score=637, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNT_EDWI9 (C5BDQ8)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002932841.1
- GeneID:   7962233
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1417
- OMA:   CPLGIAL
- ProtClustDB:   PRK13279
- HAMAP:   MF_01165
- InterPro:   IPR022839
- InterPro:   IPR003342

Pfam domain/function: PF02366 PMT

EC number: =2.4.2.43

Molecular weight: Translated: 61274; Mature: 61274

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c5d1fc8)-; HASH(0x1bc74a2c)-; HASH(0x1ae037f4)-; HASH(0x1becd7d8)-; HASH(0x4081402c)-; HASH(0x4083d378)-; HASH(0x1bffb4b8)-; HASH(0x40832254)-; HASH(0x1bde5298)-; HASH(0x1befb334)-; HASH(0x1a85cc24)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEEEEECCCH
>Mature Secondary Structure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CCEEEEEECCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA