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The map label for this gene is 238919274

Identifier: 238919274

GI number: 238919274

Start: 1353479

End: 1353829

Strand: Direct

Name: 238919274

Synonym: NT01EI_1364

Alternate gene names: NA

Gene position: 1353479-1353829 (Clockwise)

Preceding gene: 238919273

Following gene: 238919275

Centisome position: 35.5

GC content: 54.99

Gene sequence:

>351_bases
GTGATTACGGTTCAGGATGTGGAGAAAACGCTGGCGTTTTATGTCGCCGGTCTGGGGATGTCGCTGGACAGCCGCAATGG
CCGTCTGGCCCTGACGTTTGGTACGCAAAAAATCAATATTCACCGTCAGAAGGCCGAATTTACCCCGGCGGCGCAAAACG
TGACCTATGGCAGTGTGGATATATGCTTTGTCGCCGAAGGTGATATCGAACAAATCAAGGCTGAGCTGGAAAACCGGGGG
CTGGAGATCGAACTCGGCGTGGTGCCGCGCACCGGTGCCCAGGGGCCGATTGATAGCGTCTACCTGCGCGACCCTGACGG
TAATCTGGTCGAGATCAGTGTCTATAAATAA

Upstream 100 bases:

>100_bases
ATCCACTGCTGCTGCCGTGGATGATAAGTCAGGGAAGTTATATTTATTACGCTGATTTATCATGAGGTGTTTTATGTTAA
TTACAGGCATAGATCATGTA

Downstream 100 bases:

>100_bases
TAGATGGGCTTACCGATAGCATAATAATCAAATTCTATTATTACAGCGGTTGACCATGGATGGTATTTGCGGTTTCTTTT
CCTCCGGGGCGCGGGGAACA

Product: glyoxalase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MITVQDVEKTLAFYVAGLGMSLDSRNGRLALTFGTQKINIHRQKAEFTPAAQNVTYGSVDICFVAEGDIEQIKAELENRG
LEIELGVVPRTGAQGPIDSVYLRDPDGNLVEISVYK

Sequences:

>Translated_116_residues
MITVQDVEKTLAFYVAGLGMSLDSRNGRLALTFGTQKINIHRQKAEFTPAAQNVTYGSVDICFVAEGDIEQIKAELENRG
LEIELGVVPRTGAQGPIDSVYLRDPDGNLVEISVYK
>Mature_116_residues
MITVQDVEKTLAFYVAGLGMSLDSRNGRLALTFGTQKINIHRQKAEFTPAAQNVTYGSVDICFVAEGDIEQIKAELENRG
LEIELGVVPRTGAQGPIDSVYLRDPDGNLVEISVYK

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=116, Percent_Identity=44.8275862068966, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 12687; Mature: 12687

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVQDVEKTLAFYVAGLGMSLDSRNGRLALTFGTQKINIHRQKAEFTPAAQNVTYGSVD
CCCHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCEEEEEEECCCCCCCCCCCCEECCEE
ICFVAEGDIEQIKAELENRGLEIELGVVPRTGAQGPIDSVYLRDPDGNLVEISVYK
EEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCCEEEEEEEC
>Mature Secondary Structure
MITVQDVEKTLAFYVAGLGMSLDSRNGRLALTFGTQKINIHRQKAEFTPAAQNVTYGSVD
CCCHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCEEEEEEECCCCCCCCCCCCEECCEE
ICFVAEGDIEQIKAELENRGLEIELGVVPRTGAQGPIDSVYLRDPDGNLVEISVYK
EEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]