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The map label for this gene is pepN [H]

Identifier: 238919272

GI number: 238919272

Start: 1349514

End: 1352135

Strand: Direct

Name: pepN [H]

Synonym: NT01EI_1362

Alternate gene names: 238919272

Gene position: 1349514-1352135 (Clockwise)

Preceding gene: 238919268

Following gene: 238919273

Centisome position: 35.4

GC content: 63.04

Gene sequence:

>2622_bases
ATGACTCAGCAACAACCACAGGCGAAATATCGCCGCGACTATAAAACGCCGGATTACACCATTACCGATCTGGAGCTGGA
TTTTGTACTCGATGCGGACTGCACAACGGTGACGGCCGTCAGTCAGGTGATGCGGTTGGGGAGCCCGGGGGCGGCACTGG
TGCTCGACGGCGAGGCGCTGACCCTGCGCAGCCTGTCCGTGGATGGCGTCACCTGGATGGCATACCGGATTGAGGGTAAT
CAGCTGATCGTCGACGGACTGCCGGCGCAGTTTACCCTGACCATCGTCAACGAGATTCATCCGGCGCAAAACAGCGCCCT
TGAGGGGCTATACCAGTCAGGCGAGGCGCTGTGCACCCAGTGCGAGGCCGAGGGCTTCCGCCATATTACCTACTGTCTGG
ATCGCCCCGACGTGCTGGCCCGGTTCCGTACCCGCATCGTAGCGGACAAAGCGCGCTATCCCTACCTGCTGTCCAACGGC
AACCGCGTAGGCCAGGGCGAGCTGGAGGACGGGCGCCACTGGGTGCAGTGGGAGGATCCGTTCCCCAAGCCCTGCTATCT
GTTCGCCCTGGTGGCCGGTGACTTCGATCGGCTGAGCGATACCTTTATTACCCGCAGCGGGCGTCGGGTGGCGCTGGAGC
TGTACGTCGATCGCGGTAACCTCGATCGCGCCGACTGGGCGATGACCTCGCTGAAAAACGCCATGCGCTGGGACGAGCAG
CGCTTCGGTCTGGAGTACGACCTGGATATCTATATGGTCGTGGCGGTGGACTTCTTCAATATGGGGGCGATGGAGAACAA
GGGGCTGAATATCTTCAACGCCAAGTTCGTGCTGGCCAAGGCGCAGACGGCCACCGACAAGGATTATCTGAATATCGAGT
CAGTGATCGGCCACGAATATTTCCATAATTGGACCGGCAACCGGGTAACCTGTCGCGACTGGTTCCAGCTGAGTCTGAAA
GAGGGGCTGACCGTATTCCGCGATCAGGAGTTCAGCTCCGATCTGGGGTCGCGGGCGGTGAACCGCATCGACAACGTGCG
GGTGCTGCGCGGCGCCCAGTTCGCTGAGGATGCCGGCCCGATGGCGCACCCGATCCGTCCCGACAAAGTGATCGAGATGA
ATAACTTCTACACCCTGACGGTGTATGAGAAGGGCGCCGAAGTGATCCGCATGATGCACACCCTGCTGGGAGAGGAGAGG
TTCCAGGCGGGGATGCGGCTTTACTTTACGCGTCACGACGGCAGCGCCGCGACCTGCGACGATTTTGTCCAGGCGATGGA
GGACGCCTCCGGCATCGATCTGACGCAGTTCCGTCGCTGGTACAGCCAGTCTGGTACCCCGCTGCTGACGGTGCGCGACG
AATATGACGCCGAGCGCCGGCAGTACCGGCTGTATGTGACCCAGACGACCCCCGCCACGGCGGATCAGGCGGAGAAGCTG
CCGCTGCATATTCCGCTGGATATTGAGCTGTATGACGACCAGGGCGAGGTGATCCCGCTGGTGGTGAACGGCGAGCCGGT
CGGTAACGTACTGAGCGTGACCGGGGCGGAGCAGAGCTTCGCCTTTGACAACGTGCCGCAGGCGCCGACACCGTCGCTGC
TGCGGGAGTTTTCCGCGCCGGTACGCCTGGAGTATCCCTACAGCGATCGCCAGCTGACCTTCCTGATGCAGTATGCGCGC
AACGACTTTGCCCGCTGGGACGCGGCACAGATGCTGCTGGCCAAGTATGTGCGTCTGAACGTTTCGCGCAGCCAGCAGGG
GCAGCCTCTGTCGCTGCCGGAGCATGTGGTGGCGGCGTTTGGCAGCGTGCTGGCGGATGAGCGCCAGGATCCGGCGCTGC
GGGCGCAGATCCTGACCCTGCCGTCAGAGGTGGAGATGGCCGAGCTGTTCAGCCAGATCGACCCCGGGGCCATCGCCCAG
GTACACCAGGCGTTGACCCGTCTGTTGGCCCGGCAGCTGGCGGCGGAGTGGCTGCAGGCGTATCAGCGCAACACCACGCC
GCAGTACCGCATCGAGCATGGCGATATCGCCAGGCGGGCGCTGCGTAACGTCTGCCTGCGCTACCTGGCGTTTGGTGATG
ATGTGGCTCAGGCGGATGCCCTGGTCAGCACCCAGTATCGCGATGCAGATAATATGACCGATGCGCTCGGCGCCCTGTCG
GCGGCGGTGGCCGCACAGCTGCCCTGTCGCGAGACGCTGATGGCGCAGTTCGATCAACGCTGGCATCAGGATGGGCTGGT
AATGGATAAGTGGTTTACCCTGCAGGCGACCGCACCGGATGATGGGGTGCTGGCCCAGGTGCGCGCGCTGCTGCAACACC
GCGCATTTACCCTGAGCAATCCGAACCGCACCCGGGCGCTGGTAGGGGCCTTTGCCCAGCTGAACCCGCGCGCGTTCCAT
GCGGCCGACGGCTCTGGCTATGCTTTCCTGACGGAGATCCTGATGGATCTGAACACCCGCAATCCGCAGGTCGCCGCCCG
CATGGTGGATCCGCTGATCCGGCTGAAGCGCTATGACGCCGGGCGTCAGGCTCTGATGCGTCAGCAGCTGGAGTCCCTGC
TGGCGCTGGAAAATCTCTCCGGTGATCTGTATGAGAAGATCACCCGGGCACTGGAGGCCTGA

Upstream 100 bases:

>100_bases
GGTACCGGACAGATACGATGCCGTACGGATTGCACAGGTAAACCGGCCGACGGGGTCGGGCGCCTGGCGCTCCTCCAAAG
ACAGCCAATTAAGGGTAGCT

Downstream 100 bases:

>100_bases
TCCCTCGCCGCCGCGCATCCTTCGGCTCGCGGTGCCACGCCATGACGATACCGGCCTGCGGGCCGGTATTTTTGTCGCTG
CCGTGCGGTGTGGGAAGGCG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 873; Mature: 872

Protein sequence:

>873_residues
MTQQQPQAKYRRDYKTPDYTITDLELDFVLDADCTTVTAVSQVMRLGSPGAALVLDGEALTLRSLSVDGVTWMAYRIEGN
QLIVDGLPAQFTLTIVNEIHPAQNSALEGLYQSGEALCTQCEAEGFRHITYCLDRPDVLARFRTRIVADKARYPYLLSNG
NRVGQGELEDGRHWVQWEDPFPKPCYLFALVAGDFDRLSDTFITRSGRRVALELYVDRGNLDRADWAMTSLKNAMRWDEQ
RFGLEYDLDIYMVVAVDFFNMGAMENKGLNIFNAKFVLAKAQTATDKDYLNIESVIGHEYFHNWTGNRVTCRDWFQLSLK
EGLTVFRDQEFSSDLGSRAVNRIDNVRVLRGAQFAEDAGPMAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMMHTLLGEER
FQAGMRLYFTRHDGSAATCDDFVQAMEDASGIDLTQFRRWYSQSGTPLLTVRDEYDAERRQYRLYVTQTTPATADQAEKL
PLHIPLDIELYDDQGEVIPLVVNGEPVGNVLSVTGAEQSFAFDNVPQAPTPSLLREFSAPVRLEYPYSDRQLTFLMQYAR
NDFARWDAAQMLLAKYVRLNVSRSQQGQPLSLPEHVVAAFGSVLADERQDPALRAQILTLPSEVEMAELFSQIDPGAIAQ
VHQALTRLLARQLAAEWLQAYQRNTTPQYRIEHGDIARRALRNVCLRYLAFGDDVAQADALVSTQYRDADNMTDALGALS
AAVAAQLPCRETLMAQFDQRWHQDGLVMDKWFTLQATAPDDGVLAQVRALLQHRAFTLSNPNRTRALVGAFAQLNPRAFH
AADGSGYAFLTEILMDLNTRNPQVAARMVDPLIRLKRYDAGRQALMRQQLESLLALENLSGDLYEKITRALEA

Sequences:

>Translated_873_residues
MTQQQPQAKYRRDYKTPDYTITDLELDFVLDADCTTVTAVSQVMRLGSPGAALVLDGEALTLRSLSVDGVTWMAYRIEGN
QLIVDGLPAQFTLTIVNEIHPAQNSALEGLYQSGEALCTQCEAEGFRHITYCLDRPDVLARFRTRIVADKARYPYLLSNG
NRVGQGELEDGRHWVQWEDPFPKPCYLFALVAGDFDRLSDTFITRSGRRVALELYVDRGNLDRADWAMTSLKNAMRWDEQ
RFGLEYDLDIYMVVAVDFFNMGAMENKGLNIFNAKFVLAKAQTATDKDYLNIESVIGHEYFHNWTGNRVTCRDWFQLSLK
EGLTVFRDQEFSSDLGSRAVNRIDNVRVLRGAQFAEDAGPMAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMMHTLLGEER
FQAGMRLYFTRHDGSAATCDDFVQAMEDASGIDLTQFRRWYSQSGTPLLTVRDEYDAERRQYRLYVTQTTPATADQAEKL
PLHIPLDIELYDDQGEVIPLVVNGEPVGNVLSVTGAEQSFAFDNVPQAPTPSLLREFSAPVRLEYPYSDRQLTFLMQYAR
NDFARWDAAQMLLAKYVRLNVSRSQQGQPLSLPEHVVAAFGSVLADERQDPALRAQILTLPSEVEMAELFSQIDPGAIAQ
VHQALTRLLARQLAAEWLQAYQRNTTPQYRIEHGDIARRALRNVCLRYLAFGDDVAQADALVSTQYRDADNMTDALGALS
AAVAAQLPCRETLMAQFDQRWHQDGLVMDKWFTLQATAPDDGVLAQVRALLQHRAFTLSNPNRTRALVGAFAQLNPRAFH
AADGSGYAFLTEILMDLNTRNPQVAARMVDPLIRLKRYDAGRQALMRQQLESLLALENLSGDLYEKITRALEA
>Mature_872_residues
TQQQPQAKYRRDYKTPDYTITDLELDFVLDADCTTVTAVSQVMRLGSPGAALVLDGEALTLRSLSVDGVTWMAYRIEGNQ
LIVDGLPAQFTLTIVNEIHPAQNSALEGLYQSGEALCTQCEAEGFRHITYCLDRPDVLARFRTRIVADKARYPYLLSNGN
RVGQGELEDGRHWVQWEDPFPKPCYLFALVAGDFDRLSDTFITRSGRRVALELYVDRGNLDRADWAMTSLKNAMRWDEQR
FGLEYDLDIYMVVAVDFFNMGAMENKGLNIFNAKFVLAKAQTATDKDYLNIESVIGHEYFHNWTGNRVTCRDWFQLSLKE
GLTVFRDQEFSSDLGSRAVNRIDNVRVLRGAQFAEDAGPMAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMMHTLLGEERF
QAGMRLYFTRHDGSAATCDDFVQAMEDASGIDLTQFRRWYSQSGTPLLTVRDEYDAERRQYRLYVTQTTPATADQAEKLP
LHIPLDIELYDDQGEVIPLVVNGEPVGNVLSVTGAEQSFAFDNVPQAPTPSLLREFSAPVRLEYPYSDRQLTFLMQYARN
DFARWDAAQMLLAKYVRLNVSRSQQGQPLSLPEHVVAAFGSVLADERQDPALRAQILTLPSEVEMAELFSQIDPGAIAQV
HQALTRLLARQLAAEWLQAYQRNTTPQYRIEHGDIARRALRNVCLRYLAFGDDVAQADALVSTQYRDADNMTDALGALSA
AVAAQLPCRETLMAQFDQRWHQDGLVMDKWFTLQATAPDDGVLAQVRALLQHRAFTLSNPNRTRALVGAFAQLNPRAFHA
ADGSGYAFLTEILMDLNTRNPQVAARMVDPLIRLKRYDAGRQALMRQQLESLLALENLSGDLYEKITRALEA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=433, Percent_Identity=26.7898383371824, Blast_Score=133, Evalue=7e-31,
Organism=Homo sapiens, GI132814467, Length=383, Percent_Identity=26.6318537859008, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI61742777, Length=378, Percent_Identity=25.9259259259259, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI61742775, Length=378, Percent_Identity=25.9259259259259, Blast_Score=114, Evalue=6e-25,
Organism=Homo sapiens, GI194239713, Length=352, Percent_Identity=26.4204545454545, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI310133497, Length=331, Percent_Identity=27.4924471299094, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI310123622, Length=331, Percent_Identity=27.4924471299094, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI94818891, Length=502, Percent_Identity=25.6972111553785, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI94818901, Length=502, Percent_Identity=25.6972111553785, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI194306629, Length=457, Percent_Identity=25.8205689277899, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI11641261, Length=457, Percent_Identity=25.8205689277899, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI7019561, Length=391, Percent_Identity=26.5984654731458, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI4505029, Length=402, Percent_Identity=24.8756218905473, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI157266300, Length=356, Percent_Identity=24.7191011235955, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1787163, Length=868, Percent_Identity=73.3870967741936, Blast_Score=1315, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989071, Length=349, Percent_Identity=28.3667621776504, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71989076, Length=349, Percent_Identity=28.3667621776504, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17569221, Length=351, Percent_Identity=26.2108262108262, Blast_Score=109, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17569225, Length=382, Percent_Identity=26.4397905759162, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115533276, Length=370, Percent_Identity=25.6756756756757, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115533278, Length=370, Percent_Identity=25.6756756756757, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI133903840, Length=450, Percent_Identity=22.6666666666667, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193206928, Length=406, Percent_Identity=25.615763546798, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193206926, Length=411, Percent_Identity=26.2773722627737, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565628, Length=309, Percent_Identity=26.537216828479, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544504, Length=438, Percent_Identity=24.4292237442922, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990873, Length=405, Percent_Identity=21.7283950617284, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI9755335, Length=343, Percent_Identity=26.2390670553936, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321837, Length=402, Percent_Identity=25.8706467661692, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324283, Length=462, Percent_Identity=23.3766233766234, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655257, Length=399, Percent_Identity=27.5689223057644, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24655252, Length=399, Percent_Identity=27.5689223057644, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24655274, Length=410, Percent_Identity=27.0731707317073, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24655260, Length=410, Percent_Identity=27.0731707317073, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24655265, Length=410, Percent_Identity=27.0731707317073, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24655268, Length=410, Percent_Identity=27.0731707317073, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24646518, Length=380, Percent_Identity=27.8947368421053, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646516, Length=379, Percent_Identity=27.9683377308707, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646514, Length=346, Percent_Identity=27.1676300578035, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24651025, Length=391, Percent_Identity=27.3657289002558, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24651023, Length=391, Percent_Identity=27.3657289002558, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24651021, Length=391, Percent_Identity=27.3657289002558, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI221379089, Length=345, Percent_Identity=27.8260869565217, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646512, Length=400, Percent_Identity=26, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646510, Length=400, Percent_Identity=26, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21358341, Length=356, Percent_Identity=26.685393258427, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648786, Length=380, Percent_Identity=26.5789473684211, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24651016, Length=295, Percent_Identity=26.7796610169492, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650973, Length=412, Percent_Identity=25, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI45550850, Length=412, Percent_Identity=25, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI161078673, Length=538, Percent_Identity=24.1635687732342, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571901, Length=538, Percent_Identity=24.1635687732342, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571792, Length=356, Percent_Identity=24.7191011235955, Blast_Score=81, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 98646; Mature: 98515

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQQPQAKYRRDYKTPDYTITDLELDFVLDADCTTVTAVSQVMRLGSPGAALVLDGEAL
CCCCCCCHHHHHCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCEE
TLRSLSVDGVTWMAYRIEGNQLIVDGLPAQFTLTIVNEIHPAQNSALEGLYQSGEALCTQ
EEEEECCCCEEEEEEEEECCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHCCHHHHHH
CEAEGFRHITYCLDRPDVLARFRTRIVADKARYPYLLSNGNRVGQGELEDGRHWVQWEDP
HHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCEEEEECCC
FPKPCYLFALVAGDFDRLSDTFITRSGRRVALELYVDRGNLDRADWAMTSLKNAMRWDEQ
CCCCEEEEEEHHCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCHHH
RFGLEYDLDIYMVVAVDFFNMGAMENKGLNIFNAKFVLAKAQTATDKDYLNIESVIGHEY
HCCCEECCCEEEEEEEHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHH
FHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRIDNVRVLRGAQFAEDAGP
HHCCCCCEEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCEEEECCCCHHHHCCC
MAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMMHTLLGEERFQAGMRLYFTRHDGSAATCD
CCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCHHHHCCCEEEEEEECCCCCCCHH
DFVQAMEDASGIDLTQFRRWYSQSGTPLLTVRDEYDAERRQYRLYVTQTTPATADQAEKL
HHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCC
PLHIPLDIELYDDQGEVIPLVVNGEPVGNVLSVTGAEQSFAFDNVPQAPTPSLLREFSAP
CEEECEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCC
VRLEYPYSDRQLTFLMQYARNDFARWDAAQMLLAKYVRLNVSRSQQGQPLSLPEHVVAAF
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
GSVLADERQDPALRAQILTLPSEVEMAELFSQIDPGAIAQVHQALTRLLARQLAAEWLQA
HHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YQRNTTPQYRIEHGDIARRALRNVCLRYLAFGDDVAQADALVSTQYRDADNMTDALGALS
HHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
AAVAAQLPCRETLMAQFDQRWHQDGLVMDKWFTLQATAPDDGVLAQVRALLQHRAFTLSN
HHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCEECCC
PNRTRALVGAFAQLNPRAFHAADGSGYAFLTEILMDLNTRNPQVAARMVDPLIRLKRYDA
CCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
GRQALMRQQLESLLALENLSGDLYEKITRALEA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TQQQPQAKYRRDYKTPDYTITDLELDFVLDADCTTVTAVSQVMRLGSPGAALVLDGEAL
CCCCCCHHHHHCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCEE
TLRSLSVDGVTWMAYRIEGNQLIVDGLPAQFTLTIVNEIHPAQNSALEGLYQSGEALCTQ
EEEEECCCCEEEEEEEEECCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHCCHHHHHH
CEAEGFRHITYCLDRPDVLARFRTRIVADKARYPYLLSNGNRVGQGELEDGRHWVQWEDP
HHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCEEEEECCC
FPKPCYLFALVAGDFDRLSDTFITRSGRRVALELYVDRGNLDRADWAMTSLKNAMRWDEQ
CCCCEEEEEEHHCCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCHHH
RFGLEYDLDIYMVVAVDFFNMGAMENKGLNIFNAKFVLAKAQTATDKDYLNIESVIGHEY
HCCCEECCCEEEEEEEHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHH
FHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRIDNVRVLRGAQFAEDAGP
HHCCCCCEEEEHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCEEEECCCCHHHHCCC
MAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMMHTLLGEERFQAGMRLYFTRHDGSAATCD
CCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCHHHHCCCEEEEEEECCCCCCCHH
DFVQAMEDASGIDLTQFRRWYSQSGTPLLTVRDEYDAERRQYRLYVTQTTPATADQAEKL
HHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCC
PLHIPLDIELYDDQGEVIPLVVNGEPVGNVLSVTGAEQSFAFDNVPQAPTPSLLREFSAP
CEEECEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCC
VRLEYPYSDRQLTFLMQYARNDFARWDAAQMLLAKYVRLNVSRSQQGQPLSLPEHVVAAF
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
GSVLADERQDPALRAQILTLPSEVEMAELFSQIDPGAIAQVHQALTRLLARQLAAEWLQA
HHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YQRNTTPQYRIEHGDIARRALRNVCLRYLAFGDDVAQADALVSTQYRDADNMTDALGALS
HHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
AAVAAQLPCRETLMAQFDQRWHQDGLVMDKWFTLQATAPDDGVLAQVRALLQHRAFTLSN
HHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCEECCC
PNRTRALVGAFAQLNPRAFHAADGSGYAFLTEILMDLNTRNPQVAARMVDPLIRLKRYDA
CCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
GRQALMRQQLESLLALENLSGDLYEKITRALEA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]