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The map label for this gene is clpX [H]

Identifier: 238919012

GI number: 238919012

Start: 1075090

End: 1076397

Strand: Direct

Name: clpX [H]

Synonym: NT01EI_1080

Alternate gene names: 238919012

Gene position: 1075090-1076397 (Clockwise)

Preceding gene: 238919011

Following gene: 238919014

Centisome position: 28.2

GC content: 57.34

Gene sequence:

>1308_bases
TTGGCGGGACAGCTATTAAATGAAAGAGGTTTACTGATGACAGATAAGCGCAAAGACGGTTCAGGCAAGCTGCTGTACTG
CTCTTTTTGCGGCAAAAGCCAGCATGAAGTTCGTAAGCTGATCGCCGGGCCGTCAGTGTATATCTGCGACGAGTGTGTCG
ATTTGTGCAATGACATCATTCGCGAAGAGATTAAGGATGTAACGTCGCACCGTGAGCGCAGTGCACTGCCGACGCCCCAT
GAAATTCGTCATCATCTGGATGACTATGTTATCGGTCAGGAGCAGGCGAAGAAGGTGCTGGCGGTGGCGGTGTATAACCA
CTACAAGCGCCTGCGCAACGGAGACGCCAGCAACGGCGTCGAACTGGGTAAGAGCAACATCCTGCTGATCGGCCCGACGG
GCAGCGGCAAGACCCTGCTGGCGGAGACGCTGGCGCGTCTGCTGGATGTGCCTTTCACTATGGCTGATGCCACAACGCTG
ACGGAAGCCGGCTATGTCGGTGAAGATGTTGAGAACATCATTCAGAAGCTGTTGCAGAAGTGTGATTATGATGTACAGAA
GGCCCAGCGTGGCATCGTGTATATCGATGAGATCGATAAGATCTCCCGTAAGTCAGACAACCCGTCGATCACCCGCGACG
TATCCGGCGAAGGGGTACAACAGGCGCTGCTGAAGCTGATCGAAGGTACGGTCGCTGCGGTACCGCCTCAGGGGGGGCGT
AAGCACCCGCAGCAGGAGTTCCTGCAGGTAGATACCTCCAAGATCCTGTTTATCTGTGGCGGCGCCTTTGCCGGCCTGGA
TAAAGTGATCGGCCAGCGCGTGAATACCGGCACCGGCATCGGCTTCGGCGCCAAGGTGAAGGGGAAGGCGGATAAGGCCA
GCGAAAGCGAGTTGCTGGGCCAGGTTGAGCCGGAGGATCTGATCAAGTTTGGCCTGATCCCGGAGTTTATTGGCCGTCTG
CCGGTCGTCGCGACCCTGAAAGAGCTGGATGAAGCCGCGCTGATCCAGATCCTGCAAGAGCCGAAAAACGCCCTGACCAA
GCAGTATCAGGCGCTGTTTGGTCTGGAGGGGGTCGATCTGGAGTTCCGTGACGAGGCTCTGACCGCTATCGCCAAGAAGG
CCATGGCGCGTAAGACCGGCGCGCGCGGGCTGCGCTCTATCGTTGAGGGGACGCTGCTCGACACGATGTACGATCTGCCC
TCCATGGAGAACGTGGAGAAAGTGGTCGTCGATGAGAACGTTATCAATGGCCAGAGCAAGCCGATGCTGATCTATGGTCA
GCCTGAGGCGCAGGCCTCCGGCGAGTAA

Upstream 100 bases:

>100_bases
GATATACTATAGTGATGCAAAGCGCCCCCGGGCGCTTTCGTTCGGATATCGCTGTGAACCGCGCGGGCCCTACATGCATG
GATGGGGCGTACGCCCGCCA

Downstream 100 bases:

>100_bases
CTCACCGTTACCGCTGTCGCGCGTCGCGTAGATCGCCGGCAGCGATACGGGAAATGGGGTAAAATGGGGGATAGCATCCC
CCATTTTTTTTCCGCGGGTG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MAGQLLNERGLLMTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVTSHRERSALPTPH
EIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDASNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTL
TEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGR
KHPQQEFLQVDTSKILFICGGAFAGLDKVIGQRVNTGTGIGFGAKVKGKADKASESELLGQVEPEDLIKFGLIPEFIGRL
PVVATLKELDEAALIQILQEPKNALTKQYQALFGLEGVDLEFRDEALTAIAKKAMARKTGARGLRSIVEGTLLDTMYDLP
SMENVEKVVVDENVINGQSKPMLIYGQPEAQASGE

Sequences:

>Translated_435_residues
MAGQLLNERGLLMTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVTSHRERSALPTPH
EIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDASNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTL
TEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGR
KHPQQEFLQVDTSKILFICGGAFAGLDKVIGQRVNTGTGIGFGAKVKGKADKASESELLGQVEPEDLIKFGLIPEFIGRL
PVVATLKELDEAALIQILQEPKNALTKQYQALFGLEGVDLEFRDEALTAIAKKAMARKTGARGLRSIVEGTLLDTMYDLP
SMENVEKVVVDENVINGQSKPMLIYGQPEAQASGE
>Mature_434_residues
AGQLLNERGLLMTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVTSHRERSALPTPHE
IRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDASNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLT
EAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRK
HPQQEFLQVDTSKILFICGGAFAGLDKVIGQRVNTGTGIGFGAKVKGKADKASESELLGQVEPEDLIKFGLIPEFIGRLP
VVATLKELDEAALIQILQEPKNALTKQYQALFGLEGVDLEFRDEALTAIAKKAMARKTGARGLRSIVEGTLLDTMYDLPS
MENVEKVVVDENVINGQSKPMLIYGQPEAQASGE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=342, Percent_Identity=50.5847953216374, Blast_Score=309, Evalue=3e-84,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=93.1603773584906, Blast_Score=803, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=45, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=47.4358974358974, Blast_Score=274, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=313, Percent_Identity=47.2843450479233, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=412, Percent_Identity=37.1359223300971, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=39.84375, Blast_Score=177, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=429, Percent_Identity=39.8601398601399, Blast_Score=269, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=47.3520249221184, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=47.3520249221184, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47455; Mature: 47324

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQLLNERGLLMTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDII
CCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHH
REEIKDVTSHRERSALPTPHEIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDASNGV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQK
EECCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHH
CDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGR
CCCCHHHHCCCCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCC
KHPQQEFLQVDTSKILFICGGAFAGLDKVIGQRVNTGTGIGFGAKVKGKADKASESELLG
CCCHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHC
QVEPEDLIKFGLIPEFIGRLPVVATLKELDEAALIQILQEPKNALTKQYQALFGLEGVDL
CCCHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EFRDEALTAIAKKAMARKTGARGLRSIVEGTLLDTMYDLPSMENVEKVVVDENVINGQSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCCC
PMLIYGQPEAQASGE
CEEEEECCCCCCCCC
>Mature Secondary Structure 
AGQLLNERGLLMTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDII
CCCCCCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHH
REEIKDVTSHRERSALPTPHEIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDASNGV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQK
EECCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHH
CDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGR
CCCCHHHHCCCCEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCC
KHPQQEFLQVDTSKILFICGGAFAGLDKVIGQRVNTGTGIGFGAKVKGKADKASESELLG
CCCHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHHHHC
QVEPEDLIKFGLIPEFIGRLPVVATLKELDEAALIQILQEPKNALTKQYQALFGLEGVDL
CCCHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EFRDEALTAIAKKAMARKTGARGLRSIVEGTLLDTMYDLPSMENVEKVVVDENVINGQSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCCC
PMLIYGQPEAQASGE
CEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA