Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 238918992

GI number: 238918992

Start: 1055858

End: 1056829

Strand: Direct

Name: thiL [H]

Synonym: NT01EI_1059

Alternate gene names: 238918992

Gene position: 1055858-1056829 (Clockwise)

Preceding gene: 238918991

Following gene: 238918993

Centisome position: 27.7

GC content: 63.48

Gene sequence:

>972_bases
ATGGCACACGGTGAATTTGATCTGATAGCCCGTTACTTTAACCGTCGGTCTACCCCGCGACACGATGTCCAGCGTGGTAT
CGGCGATGACTGTGCGCTGCTGTCTGTGTCGGAAAAACAGTGGGTGGCCGTCAGCAGCGATACGCTGGTCAGCGGCATTC
ATTTTTTACCGGAGATTGATCCGGTCGATCTCGGCTATAAATCCCTGGCGGTAAACATCAGCGATTTGGCGGCGATGGGG
GCTGATCCGGCCTGGGTATCACTGGCGCTGACCCTGCCCGCGGTGGACGAACCCTGGCTACAGGCCTTCAGCGATGCCCT
GTTTGAGCAGTTAGACTACTACGGTATGCAGCTGATCGGGGGGGATACGACCCGCGGCCCGCTGAGCCTGACCTATACCG
TTCAGGGATTGGTGCCGGCCGGCCGGGCGCTGCTGCGCAGCGGCGCCCGCGTGGGTGACTGGATCTATGTCACCGGGACG
CTGGGTGACAGCGCAGCGGGGCTGGCGCTGCTGCAGGCGCGCCTGACGGTGGCCGATGAGGCCGATCGGCGCTATCTGCT
CGGGCGCCATCTGCGCCCGCAGCCGCGGGTGCTACAGGGGCAGGCGCTGCGCGATCTGGCCAGCGCTGCCATCGATATTT
CCGACGGGCTACTCGCCGATTTGGGGCATATCCTCAAGGCCAGCGACTGCGGGGCCAACCTGTATCTGGATAAGCTGCCG
CTCTCGGCGGAGCTGATGTGCCACGTCGACGCCGAAACCTGCCAGCGCTGGGCACTGGGCGGTGGTGAAGACTATGAACT
GTGCTTTACCGTGCCGGAGATGTACCGCGGCGCGCTGGATATGGCGCTCGCCCAGCTGGGGTGCCGCTATACCTGCATCG
GGCAGATGGCTCCGGCGTCGGAGGGGGTATGCCTGTGGCGTGGGGAGCGTCAGGTGACGCTGGATATACAGGGGTTTGAT
CACTTTGGCTAA

Upstream 100 bases:

>100_bases
GTCGTCCGCCCGGCCTTATGGGGCCTGACAGCTATGCCACAGGCCGGTTCTCCGGCCTTTTTTTCGGCTGTGCGAACGAC
CAGATCGCAGGAAACAAGCT

Downstream 100 bases:

>100_bases
GATGACGAAGCAACAGCAGCGGGCGGCCAGGGCGCGCCTGCGTATGGGGAATCCCTGGCACCTGCTGGCGACCGGCTTTG
GCAGCGGTTTGAGCCCACTG

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAHGEFDLIARYFNRRSTPRHDVQRGIGDDCALLSVSEKQWVAVSSDTLVSGIHFLPEIDPVDLGYKSLAVNISDLAAMG
ADPAWVSLALTLPAVDEPWLQAFSDALFEQLDYYGMQLIGGDTTRGPLSLTYTVQGLVPAGRALLRSGARVGDWIYVTGT
LGDSAAGLALLQARLTVADEADRRYLLGRHLRPQPRVLQGQALRDLASAAIDISDGLLADLGHILKASDCGANLYLDKLP
LSAELMCHVDAETCQRWALGGGEDYELCFTVPEMYRGALDMALAQLGCRYTCIGQMAPASEGVCLWRGERQVTLDIQGFD
HFG

Sequences:

>Translated_323_residues
MAHGEFDLIARYFNRRSTPRHDVQRGIGDDCALLSVSEKQWVAVSSDTLVSGIHFLPEIDPVDLGYKSLAVNISDLAAMG
ADPAWVSLALTLPAVDEPWLQAFSDALFEQLDYYGMQLIGGDTTRGPLSLTYTVQGLVPAGRALLRSGARVGDWIYVTGT
LGDSAAGLALLQARLTVADEADRRYLLGRHLRPQPRVLQGQALRDLASAAIDISDGLLADLGHILKASDCGANLYLDKLP
LSAELMCHVDAETCQRWALGGGEDYELCFTVPEMYRGALDMALAQLGCRYTCIGQMAPASEGVCLWRGERQVTLDIQGFD
HFG
>Mature_322_residues
AHGEFDLIARYFNRRSTPRHDVQRGIGDDCALLSVSEKQWVAVSSDTLVSGIHFLPEIDPVDLGYKSLAVNISDLAAMGA
DPAWVSLALTLPAVDEPWLQAFSDALFEQLDYYGMQLIGGDTTRGPLSLTYTVQGLVPAGRALLRSGARVGDWIYVTGTL
GDSAAGLALLQARLTVADEADRRYLLGRHLRPQPRVLQGQALRDLASAAIDISDGLLADLGHILKASDCGANLYLDKLPL
SAELMCHVDAETCQRWALGGGEDYELCFTVPEMYRGALDMALAQLGCRYTCIGQMAPASEGVCLWRGERQVTLDIQGFDH
FG

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=322, Percent_Identity=68.6335403726708, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35030; Mature: 34899

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHGEFDLIARYFNRRSTPRHDVQRGIGDDCALLSVSEKQWVAVSSDTLVSGIHFLPEID
CCCCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCEEEECCCHHHHHHHHCCCCC
PVDLGYKSLAVNISDLAAMGADPAWVSLALTLPAVDEPWLQAFSDALFEQLDYYGMQLIG
CCCCCHHHEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEC
GDTTRGPLSLTYTVQGLVPAGRALLRSGARVGDWIYVTGTLGDSAAGLALLQARLTVADE
CCCCCCCEEEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
ADRRYLLGRHLRPQPRVLQGQALRDLASAAIDISDGLLADLGHILKASDCGANLYLDKLP
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCC
LSAELMCHVDAETCQRWALGGGEDYELCFTVPEMYRGALDMALAQLGCRYTCIGQMAPAS
CCEEEEEEECHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEEEECCCCCCC
EGVCLWRGERQVTLDIQGFDHFG
CCEEEEECCEEEEEEECCCCCCC
>Mature Secondary Structure 
AHGEFDLIARYFNRRSTPRHDVQRGIGDDCALLSVSEKQWVAVSSDTLVSGIHFLPEID
CCCHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCEEEECCCHHHHHHHHCCCCC
PVDLGYKSLAVNISDLAAMGADPAWVSLALTLPAVDEPWLQAFSDALFEQLDYYGMQLIG
CCCCCHHHEEEEHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEC
GDTTRGPLSLTYTVQGLVPAGRALLRSGARVGDWIYVTGTLGDSAAGLALLQARLTVADE
CCCCCCCEEEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
ADRRYLLGRHLRPQPRVLQGQALRDLASAAIDISDGLLADLGHILKASDCGANLYLDKLP
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEECCC
LSAELMCHVDAETCQRWALGGGEDYELCFTVPEMYRGALDMALAQLGCRYTCIGQMAPAS
CCEEEEEEECHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEEEECCCCCCC
EGVCLWRGERQVTLDIQGFDHFG
CCEEEEECCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]