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The map label for this gene is rsmA [H]

Identifier: 238917939

GI number: 238917939

Start: 2096291

End: 2097172

Strand: Direct

Name: rsmA [H]

Synonym: EUBELI_02027

Alternate gene names: 238917939

Gene position: 2096291-2097172 (Clockwise)

Preceding gene: 238917936

Following gene: 238917942

Centisome position: 97.77

GC content: 40.93

Gene sequence:

>882_bases
ATGAGCGATAATAAATATAATAATGTTATGCACCTTGGCAACCCAACTAACACGATTGCCGTGCTTAACAGATATGGTTT
TGATTTCAAGAAAAAGTTCGGGCAGAACTTTCTTATAGATGAAAATGTTGTTGAGAAAATCGTCCGTGAAGCAGGCGTTA
CCAAAGATGATTTTGTTGTTGAAGTTGGTCCGGGAATCGGAACAATGACCCAGATTCTTTGTGAGAATGCCAGAGAAGTT
GTTGCCGTTGAGATTGATAAGAAGCTTATTCCTATTCTTACAGAAGATACTCTTTCTTATTATGACAATGTGACAGTAAT
CAATGAAGATATCTTAAAGCTTGATATTAAGAAGCTTGCTGATGAGAAGAATGAAGGCAGACCAATCAAGGTTGTTGCCA
ACCTTCCATACTATATAACAACACCTATTATTATGGGACTTTTTGAGAGCCATGTACCATTAGACAGTATAACTATCATG
GTTCAGAAAGAGGTAGCTGACCGCATGCAATGTGGTCCTGGAACTAAAGATTATGGCGCACTTTCACTTGCTGTACAGTT
CTACGCCAAGCCTAAGGTTGTGCTTAATGTGCCTGCTAGCTGCTTCATGCCTCGTCCTAATGTTGATTCAGCGGTTATCC
GTCTTGAGCGCTTCAAAACCCCACCTGTTGATGTTAAGAATGAACATCTTATGTTCAAGATAATAAGAGCATCATTTAAC
CAGCGCCGAAAGACTATGCTTAACAGTGTCGGCAATTCCGGCATCGGCATCACGAAAGAAGCTCTTACCAACGCATTAGA
AACTATGGGACTTCCGCTTACTATCCGCGGCGAAGCCCTTACACTTGAGCAGTTTGCACAATTAAGCAATCTGCTGTGCT
AA

Upstream 100 bases:

>100_bases
CTATAGTATCATACAAAAGTTACTTTTGCACTACATTTTTATTGCAGCTTGACATTTTTTATTAAGTTTCATAACATTAT
TCTTATAGATTGGAGGCAAT

Downstream 100 bases:

>100_bases
ATAACATGATACCTATAAGTAGTCGCATTTTCACTGCTTTAGTAGGTTTTTTTGCAGCAAAATTCACGTAAATCAGGTTA
CTTCCAGACTAAAGACCTAT

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSDNKYNNVMHLGNPTNTIAVLNRYGFDFKKKFGQNFLIDENVVEKIVREAGVTKDDFVVEVGPGIGTMTQILCENAREV
VAVEIDKKLIPILTEDTLSYYDNVTVINEDILKLDIKKLADEKNEGRPIKVVANLPYYITTPIIMGLFESHVPLDSITIM
VQKEVADRMQCGPGTKDYGALSLAVQFYAKPKVVLNVPASCFMPRPNVDSAVIRLERFKTPPVDVKNEHLMFKIIRASFN
QRRKTMLNSVGNSGIGITKEALTNALETMGLPLTIRGEALTLEQFAQLSNLLC

Sequences:

>Translated_293_residues
MSDNKYNNVMHLGNPTNTIAVLNRYGFDFKKKFGQNFLIDENVVEKIVREAGVTKDDFVVEVGPGIGTMTQILCENAREV
VAVEIDKKLIPILTEDTLSYYDNVTVINEDILKLDIKKLADEKNEGRPIKVVANLPYYITTPIIMGLFESHVPLDSITIM
VQKEVADRMQCGPGTKDYGALSLAVQFYAKPKVVLNVPASCFMPRPNVDSAVIRLERFKTPPVDVKNEHLMFKIIRASFN
QRRKTMLNSVGNSGIGITKEALTNALETMGLPLTIRGEALTLEQFAQLSNLLC
>Mature_292_residues
SDNKYNNVMHLGNPTNTIAVLNRYGFDFKKKFGQNFLIDENVVEKIVREAGVTKDDFVVEVGPGIGTMTQILCENAREVV
AVEIDKKLIPILTEDTLSYYDNVTVINEDILKLDIKKLADEKNEGRPIKVVANLPYYITTPIIMGLFESHVPLDSITIMV
QKEVADRMQCGPGTKDYGALSLAVQFYAKPKVVLNVPASCFMPRPNVDSAVIRLERFKTPPVDVKNEHLMFKIIRASFNQ
RRKTMLNSVGNSGIGITKEALTNALETMGLPLTIRGEALTLEQFAQLSNLLC

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Homo sapiens, GI156415992, Length=281, Percent_Identity=28.4697508896797, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI7657198, Length=232, Percent_Identity=31.0344827586207, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1786236, Length=264, Percent_Identity=36.3636363636364, Blast_Score=170, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI25141369, Length=295, Percent_Identity=31.1864406779661, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25146882, Length=230, Percent_Identity=34.3478260869565, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324989, Length=212, Percent_Identity=30.188679245283, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357273, Length=293, Percent_Identity=28.3276450511945, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21358017, Length=204, Percent_Identity=32.843137254902, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 32697; Mature: 32565

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS01131 RRNA_A_DIMETH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNKYNNVMHLGNPTNTIAVLNRYGFDFKKKFGQNFLIDENVVEKIVREAGVTKDDFVV
CCCCCCCCEEECCCCCCCEEEHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEE
EVGPGIGTMTQILCENAREVVAVEIDKKLIPILTEDTLSYYDNVTVINEDILKLDIKKLA
EECCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHHCCEEEECHHHHHHHHHHHH
DEKNEGRPIKVVANLPYYITTPIIMGLFESHVPLDSITIMVQKEVADRMQCGPGTKDYGA
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCCCCHH
LSLAVQFYAKPKVVLNVPASCFMPRPNVDSAVIRLERFKTPPVDVKNEHLMFKIIRASFN
HEEEEEECCCCEEEEECCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
QRRKTMLNSVGNSGIGITKEALTNALETMGLPLTIRGEALTLEQFAQLSNLLC
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCEECHHHHHHHHHCCC
>Mature Secondary Structure 
SDNKYNNVMHLGNPTNTIAVLNRYGFDFKKKFGQNFLIDENVVEKIVREAGVTKDDFVV
CCCCCCCEEECCCCCCCEEEHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEE
EVGPGIGTMTQILCENAREVVAVEIDKKLIPILTEDTLSYYDNVTVINEDILKLDIKKLA
EECCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEHHHHHHHCCEEEECHHHHHHHHHHHH
DEKNEGRPIKVVANLPYYITTPIIMGLFESHVPLDSITIMVQKEVADRMQCGPGTKDYGA
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCCCCHH
LSLAVQFYAKPKVVLNVPASCFMPRPNVDSAVIRLERFKTPPVDVKNEHLMFKIIRASFN
HEEEEEECCCCEEEEECCHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
QRRKTMLNSVGNSGIGITKEALTNALETMGLPLTIRGEALTLEQFAQLSNLLC
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA