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The map label for this gene is dnaC [H]

Identifier: 238917869

GI number: 238917869

Start: 2015409

End: 2016755

Strand: Reverse

Name: dnaC [H]

Synonym: EUBELI_01950

Alternate gene names: 238917869

Gene position: 2016755-2015409 (Counterclockwise)

Preceding gene: 238917870

Following gene: 238917867

Centisome position: 94.06

GC content: 42.09

Gene sequence:

>1347_bases
ATGGATGAGTCAGTGGTAACACGGGTGATGCCTAACAGCATTGAAGCTGAGCAGTCTGTTGTTGGTTCAATGATTCTGGA
CAGACAGGCAATTATAACTGCCGCTGAAATCTTAAGGCAGGATGATTTCTACTACAGGCAGTATGGAACTATGTTCCAGA
CGATGGTAGACATGAATAACGAGGGAAAACCTGTAGATATAGTTACTCTGCAGGCAAGATTGAAGGAGACAGATGTACCG
GCTGAAGTCTATAGTATAGAGTTTGTAAGAGAACTGTTATCATCAGTGCCAACATCGGCTAATATAAGACAGTATGCGGG
TATTGTTAAGGAAAAAGCAGTACTCAGGAATATCATAAGAGTTAATGATGATATTGCCAATCAGTGTTATGCGGGCAAGG
AAAAGACTGAAGATATACTTGCTGATACTGAAAAGAAGATATTTGAGCTTGTTAAGAATAAGGGTGGAAAGGAATATACA
CCTATTGATAAGGTTGTTCTTGAGGCACTTGACAGAATATCTGCGGCAGCAAAGACTAAAGGTGCTGTAACAGGTGTTCC
TACAGGGTTCAAGGACTTAGATACTTATCTGTCAGGTCTGCAGCCGTCAGATTTTATTCTTGTTGCAGCCAGACCTTCAA
TGGGTAAGACCGCATTTGTCCTTAATGTTGCTGAAAATGTAGCTATCAAGCAGCAGATTACAACAGTTGTATTCAGCTTG
GAGATGTCTAATGTCCAGCTTGTAAATCGTATGTTATCACTTGAATCAACAGTGGATGCGGACAAGATAAGAAAAGGACA
TCTGGATTCTAATGACTGGGGCAAGCTTATAGAGGGTGCGGACAGCATTGCCAAGTCGAAGCTTATAATTGATGATACGC
CGGGTATCTCAATCGCAGAATTACGTAGTAAATGCAGGAAATACAAGATGGAGAATAATCTTGGACTTATTATTATCGAT
TACCTCCAGCTTATGAGTGGCAGTGGAAGCGGACGTTCTGAGGGAAGACAGCAGGAAGTATCTGACATATCCAGAGCGTT
AAAGGCACTTGCGAGAGAGTTAAATGTACCAGTAGTAACACTTTCACAGTTAAGCCGTGCAGTAGAGCAGAGACCAGACC
ACAGACCTATGCTTTCGGATCTTCGAGAGTCAGGAGCTATCGAGCAGGATGCCGACGTTGTTATGTTCCTTTACAGAGAT
GATTATTACAATAAGGATACAGAGCAGAAGGGTATTGCAGAGATTATTATTGCCAAGCAGCGTAACGGTCCTATTGGAAC
TGTTAAGATGGCATGGCTGCCGGAACAGACAAGATTTGCAGATCTTTCAAGAGACTTAAGACAGTAA

Upstream 100 bases:

>100_bases
TTATCCAGATAAAGCTTCATAAAGATGTAACAGCTGAGCTGACTGTTAAGGTTGTTGAGAAATAAATATATAAGATACAT
TTGTAAGAAGGGGAATTACT

Downstream 100 bases:

>100_bases
TTGAACATGCAAAAAAAACCCCGAATCAGTATTAAACTGGTCCGGGGTTTTATGTAAGTACCGTTCAGGTACATTGAACA
CCATCTGGTGAACATTAATC

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDESVVTRVMPNSIEAEQSVVGSMILDRQAIITAAEILRQDDFYYRQYGTMFQTMVDMNNEGKPVDIVTLQARLKETDVP
AEVYSIEFVRELLSSVPTSANIRQYAGIVKEKAVLRNIIRVNDDIANQCYAGKEKTEDILADTEKKIFELVKNKGGKEYT
PIDKVVLEALDRISAAAKTKGAVTGVPTGFKDLDTYLSGLQPSDFILVAARPSMGKTAFVLNVAENVAIKQQITTVVFSL
EMSNVQLVNRMLSLESTVDADKIRKGHLDSNDWGKLIEGADSIAKSKLIIDDTPGISIAELRSKCRKYKMENNLGLIIID
YLQLMSGSGSGRSEGRQQEVSDISRALKALARELNVPVVTLSQLSRAVEQRPDHRPMLSDLRESGAIEQDADVVMFLYRD
DYYNKDTEQKGIAEIIIAKQRNGPIGTVKMAWLPEQTRFADLSRDLRQ

Sequences:

>Translated_448_residues
MDESVVTRVMPNSIEAEQSVVGSMILDRQAIITAAEILRQDDFYYRQYGTMFQTMVDMNNEGKPVDIVTLQARLKETDVP
AEVYSIEFVRELLSSVPTSANIRQYAGIVKEKAVLRNIIRVNDDIANQCYAGKEKTEDILADTEKKIFELVKNKGGKEYT
PIDKVVLEALDRISAAAKTKGAVTGVPTGFKDLDTYLSGLQPSDFILVAARPSMGKTAFVLNVAENVAIKQQITTVVFSL
EMSNVQLVNRMLSLESTVDADKIRKGHLDSNDWGKLIEGADSIAKSKLIIDDTPGISIAELRSKCRKYKMENNLGLIIID
YLQLMSGSGSGRSEGRQQEVSDISRALKALARELNVPVVTLSQLSRAVEQRPDHRPMLSDLRESGAIEQDADVVMFLYRD
DYYNKDTEQKGIAEIIIAKQRNGPIGTVKMAWLPEQTRFADLSRDLRQ
>Mature_448_residues
MDESVVTRVMPNSIEAEQSVVGSMILDRQAIITAAEILRQDDFYYRQYGTMFQTMVDMNNEGKPVDIVTLQARLKETDVP
AEVYSIEFVRELLSSVPTSANIRQYAGIVKEKAVLRNIIRVNDDIANQCYAGKEKTEDILADTEKKIFELVKNKGGKEYT
PIDKVVLEALDRISAAAKTKGAVTGVPTGFKDLDTYLSGLQPSDFILVAARPSMGKTAFVLNVAENVAIKQQITTVVFSL
EMSNVQLVNRMLSLESTVDADKIRKGHLDSNDWGKLIEGADSIAKSKLIIDDTPGISIAELRSKCRKYKMENNLGLIIID
YLQLMSGSGSGRSEGRQQEVSDISRALKALARELNVPVVTLSQLSRAVEQRPDHRPMLSDLRESGAIEQDADVVMFLYRD
DYYNKDTEQKGIAEIIIAKQRNGPIGTVKMAWLPEQTRFADLSRDLRQ

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=441, Percent_Identity=45.3514739229025, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49920; Mature: 49920

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESVVTRVMPNSIEAEQSVVGSMILDRQAIITAAEILRQDDFYYRQYGTMFQTMVDMNN
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
EGKPVDIVTLQARLKETDVPAEVYSIEFVRELLSSVPTSANIRQYAGIVKEKAVLRNIIR
CCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VNDDIANQCYAGKEKTEDILADTEKKIFELVKNKGGKEYTPIDKVVLEALDRISAAAKTK
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GAVTGVPTGFKDLDTYLSGLQPSDFILVAARPSMGKTAFVLNVAENVAIKQQITTVVFSL
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
EMSNVQLVNRMLSLESTVDADKIRKGHLDSNDWGKLIEGADSIAKSKLIIDDTPGISIAE
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHH
LRSKCRKYKMENNLGLIIIDYLQLMSGSGSGRSEGRQQEVSDISRALKALARELNVPVVT
HHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
LSQLSRAVEQRPDHRPMLSDLRESGAIEQDADVVMFLYRDDYYNKDTEQKGIAEIIIAKQ
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHCCHHHHEEEEC
RNGPIGTVKMAWLPEQTRFADLSRDLRQ
CCCCCCEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDESVVTRVMPNSIEAEQSVVGSMILDRQAIITAAEILRQDDFYYRQYGTMFQTMVDMNN
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
EGKPVDIVTLQARLKETDVPAEVYSIEFVRELLSSVPTSANIRQYAGIVKEKAVLRNIIR
CCCCEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VNDDIANQCYAGKEKTEDILADTEKKIFELVKNKGGKEYTPIDKVVLEALDRISAAAKTK
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
GAVTGVPTGFKDLDTYLSGLQPSDFILVAARPSMGKTAFVLNVAENVAIKQQITTVVFSL
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
EMSNVQLVNRMLSLESTVDADKIRKGHLDSNDWGKLIEGADSIAKSKLIIDDTPGISIAE
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHH
LRSKCRKYKMENNLGLIIIDYLQLMSGSGSGRSEGRQQEVSDISRALKALARELNVPVVT
HHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
LSQLSRAVEQRPDHRPMLSDLRESGAIEQDADVVMFLYRDDYYNKDTEQKGIAEIIIAKQ
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHCCHHHHEEEEC
RNGPIGTVKMAWLPEQTRFADLSRDLRQ
CCCCCCEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]