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The map label for this gene is mecA2 [H]

Identifier: 238917866

GI number: 238917866

Start: 2013746

End: 2014594

Strand: Direct

Name: mecA2 [H]

Synonym: EUBELI_01947

Alternate gene names: 238917866

Gene position: 2013746-2014594 (Clockwise)

Preceding gene: 238917856

Following gene: 238917868

Centisome position: 93.92

GC content: 35.69

Gene sequence:

>849_bases
ATGAAAATAGAAAGACTTAATGAAAATCAGATCAGATGCACACTTAACAAGTCCGATCTGGCTTCAAGACATTTGAAAAT
CAACGAGCTTGCCTATGGCAGCGATAAAGCGAAAGAACTTTTTCGTGATATGATGCAGCAGGCATCGTATGAATTAGGCT
TTGAAGCAGAGGACACTCCTTTAATGATAGAGGCAATTCCTGTTTCAGCAGAATGTATTGTTCTTATTGTTACTAAAGTT
GATAATCCTGAAGAACTTGATACCCGTTTTTCCCGTTTCTCACCGTCAGATTCTGATGATGATGACGGCTTTGATTTTGA
TGATATAGAGACAATTGAAAGCAACGGCTACTCATCCTATTCTCCTCCTAAAGCTAACGAAGAACTTGATGAAGAAAGCG
CCGCTACTGAGGAAGATAATAACATTTCAGAAGATAATCTTATGAATATATTAGACCGTGTTAAGGAGTATTTTAATAAT
AAAGAAACTTCCGGCAAAAAATCCGGTGAGTCTGACACCTCAGAAAACAAACCTACTGTTAAAGAAGCATCCAGCCATAT
TGTCAGAGTGTTTTCATTCGGTTCACTTGATGATATCAGTAGTGCTGCCCGGATAATTAACCGCTTTTACCACGATAATA
ACTCTGTTTATAAGAATCCATCTGATAAGCGTTATTATCTCACAATTTCCAAAAACAAAACATCTTCTAAAGATTTTAAT
AAAGTATGCAACATTCTTTCTGAATATGGTAATAAAGAAGCTGCATTCGATAATTATACAGGTTTCTTTTCAGAGCATTG
TGAATGTATTGTAAAAGAACATGCCATTCATATTCTAAGCAGACTATAA

Upstream 100 bases:

>100_bases
TATTTATTTTACTACTGCTTTCTTACACCGCCTTTACATATCCATAAAAAATGGGTATTATATCTTTACGATAATTAACA
AATTTAGTCAGAGGTGGCTT

Downstream 100 bases:

>100_bases
TAACAGAGCCGGAGCAATTAAATCTAATGCTCCGGCTCTGTTATTATCACTCATTGTCTGTATTTATCCAATAGACTGAA
GATAATTCTGAATCTCCTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKIERLNENQIRCTLNKSDLASRHLKINELAYGSDKAKELFRDMMQQASYELGFEAEDTPLMIEAIPVSAECIVLIVTKV
DNPEELDTRFSRFSPSDSDDDDGFDFDDIETIESNGYSSYSPPKANEELDEESAATEEDNNISEDNLMNILDRVKEYFNN
KETSGKKSGESDTSENKPTVKEASSHIVRVFSFGSLDDISSAARIINRFYHDNNSVYKNPSDKRYYLTISKNKTSSKDFN
KVCNILSEYGNKEAAFDNYTGFFSEHCECIVKEHAIHILSRL

Sequences:

>Translated_282_residues
MKIERLNENQIRCTLNKSDLASRHLKINELAYGSDKAKELFRDMMQQASYELGFEAEDTPLMIEAIPVSAECIVLIVTKV
DNPEELDTRFSRFSPSDSDDDDGFDFDDIETIESNGYSSYSPPKANEELDEESAATEEDNNISEDNLMNILDRVKEYFNN
KETSGKKSGESDTSENKPTVKEASSHIVRVFSFGSLDDISSAARIINRFYHDNNSVYKNPSDKRYYLTISKNKTSSKDFN
KVCNILSEYGNKEAAFDNYTGFFSEHCECIVKEHAIHILSRL
>Mature_282_residues
MKIERLNENQIRCTLNKSDLASRHLKINELAYGSDKAKELFRDMMQQASYELGFEAEDTPLMIEAIPVSAECIVLIVTKV
DNPEELDTRFSRFSPSDSDDDDGFDFDDIETIESNGYSSYSPPKANEELDEESAATEEDNNISEDNLMNILDRVKEYFNN
KETSGKKSGESDTSENKPTVKEASSHIVRVFSFGSLDDISSAARIINRFYHDNNSVYKNPSDKRYYLTISKNKTSSKDFN
KVCNILSEYGNKEAAFDNYTGFFSEHCECIVKEHAIHILSRL

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 32098; Mature: 32098

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIERLNENQIRCTLNKSDLASRHLKINELAYGSDKAKELFRDMMQQASYELGFEAEDTP
CCCCCCCCCCEEEEECHHHHHHHCEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LMIEAIPVSAECIVLIVTKVDNPEELDTRFSRFSPSDSDDDDGFDFDDIETIESNGYSSY
EEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCC
SPPKANEELDEESAATEEDNNISEDNLMNILDRVKEYFNNKETSGKKSGESDTSENKPTV
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
KEASSHIVRVFSFGSLDDISSAARIINRFYHDNNSVYKNPSDKRYYLTISKNKTSSKDFN
HHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCCCHHHH
KVCNILSEYGNKEAAFDNYTGFFSEHCECIVKEHAIHILSRL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIERLNENQIRCTLNKSDLASRHLKINELAYGSDKAKELFRDMMQQASYELGFEAEDTP
CCCCCCCCCCEEEEECHHHHHHHCEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LMIEAIPVSAECIVLIVTKVDNPEELDTRFSRFSPSDSDDDDGFDFDDIETIESNGYSSY
EEEEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCC
SPPKANEELDEESAATEEDNNISEDNLMNILDRVKEYFNNKETSGKKSGESDTSENKPTV
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
KEASSHIVRVFSFGSLDDISSAARIINRFYHDNNSVYKNPSDKRYYLTISKNKTSSKDFN
HHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCCCHHHH
KVCNILSEYGNKEAAFDNYTGFFSEHCECIVKEHAIHILSRL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]