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The map label for this gene is pth

Identifier: 238917834

GI number: 238917834

Start: 1982825

End: 1983385

Strand: Reverse

Name: pth

Synonym: EUBELI_01915

Alternate gene names: 238917834

Gene position: 1983385-1982825 (Counterclockwise)

Preceding gene: 238917835

Following gene: 238917833

Centisome position: 92.5

GC content: 38.15

Gene sequence:

>561_bases
ATGTATATAATAGCGGGACTTGGTAATCCGGGTAAAGAATATATGGGAACAAGACACAATGCAGGATTTTCAGTAATAGA
CGAGCTTGCAGACAAATATAATATCAGTGTGGACACAGCAAAGCACAAGGGACTTATCGGAAAAGGCGTAATAGCAGGTC
AGAAAGTAATACTTGTTAAGCCTATGACATATATGAATAATTCAGGCGAGTGTATAAGAGAAGTTATGGATTATTACAAA
TGTGATATAGATGATTTTCTTGTTATCTTTGATGATATAAGTCTTGATGTAGGTAAGCTAAGACTCCGTGCAAAGGGAAG
TGCAGGTGGACACAATGGAATCAAGAGTATAATAGCACATCTTGGAAGCGACAAGTTCAAGAGAATAAAGTTCGGAGTCG
GCGATAAGCCTAAGAACTGGGATCTTGCAGACTGGGTGCTTGGGAAATTTCCTGCAGAGGAATATGCAACATTAAGAGAG
GCTAATAAGAAAGCCTGTGAAGCTGTAGAATGCATACTTACAGATGGAATAGAAAGTGGTATGAATAAATATAACGGATA
A

Upstream 100 bases:

>100_bases
GCCAGCCTGTGAAAGCAGACTGGCTCTTTTGTACTTGCTTTAAATTTATTGAATAAGTATAATCTCAATAAATGTTATAA
TAAAAAGAGAGGAAAACACA

Downstream 100 bases:

>100_bases
CTGGTGGTATAATATGAAAGCAATATTTGAGCCGGTGTATAATACAGCCGGTGTGGAACAACTTAATAAAGAGCTTGCTA
AAGATGGTGGCAGAACAGTA

Product: hypothetical protein

Products: NA

Alternate protein names: PTH

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MYIIAGLGNPGKEYMGTRHNAGFSVIDELADKYNISVDTAKHKGLIGKGVIAGQKVILVKPMTYMNNSGECIREVMDYYK
CDIDDFLVIFDDISLDVGKLRLRAKGSAGGHNGIKSIIAHLGSDKFKRIKFGVGDKPKNWDLADWVLGKFPAEEYATLRE
ANKKACEAVECILTDGIESGMNKYNG

Sequences:

>Translated_186_residues
MYIIAGLGNPGKEYMGTRHNAGFSVIDELADKYNISVDTAKHKGLIGKGVIAGQKVILVKPMTYMNNSGECIREVMDYYK
CDIDDFLVIFDDISLDVGKLRLRAKGSAGGHNGIKSIIAHLGSDKFKRIKFGVGDKPKNWDLADWVLGKFPAEEYATLRE
ANKKACEAVECILTDGIESGMNKYNG
>Mature_186_residues
MYIIAGLGNPGKEYMGTRHNAGFSVIDELADKYNISVDTAKHKGLIGKGVIAGQKVILVKPMTYMNNSGECIREVMDYYK
CDIDDFLVIFDDISLDVGKLRLRAKGSAGGHNGIKSIIAHLGSDKFKRIKFGVGDKPKNWDLADWVLGKFPAEEYATLRE
ANKKACEAVECILTDGIESGMNKYNG

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis

COG id: COG0193

COG function: function code J; Peptidyl-tRNA hydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH family

Homologues:

Organism=Homo sapiens, GI50897284, Length=157, Percent_Identity=29.2993630573248, Blast_Score=88, Evalue=6e-18,
Organism=Escherichia coli, GI1787455, Length=186, Percent_Identity=34.4086021505376, Blast_Score=104, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321983, Length=173, Percent_Identity=31.7919075144509, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTH_EUBE2 (C4Z4L5)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002931351.1
- GeneID:   7957656
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_01915
- OMA:   SHAGHNG
- ProtClustDB:   CLSK2540824
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_00083
- InterPro:   IPR001328
- InterPro:   IPR018171
- Gene3D:   G3DSA:3.40.50.1470
- PANTHER:   PTHR17224
- TIGRFAMs:   TIGR00447

Pfam domain/function: PF01195 Pept_tRNA_hydro; SSF53178 Pept_tRNA_hydro

EC number: =3.1.1.29

Molecular weight: Translated: 20441; Mature: 20441

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS01195 PEPT_TRNA_HYDROL_1; PS01196 PEPT_TRNA_HYDROL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIIAGLGNPGKEYMGTRHNAGFSVIDELADKYNISVDTAKHKGLIGKGVIAGQKVILVK
CEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHCCCEECHHHCCCCCCCEECCCEEEEEC
PMTYMNNSGECIREVMDYYKCDIDDFLVIFDDISLDVGKLRLRAKGSAGGHNGIKSIIAH
CHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHH
LGSDKFKRIKFGVGDKPKNWDLADWVLGKFPAEEYATLREANKKACEAVECILTDGIESG
HCCCHHEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNKYNG
HHHCCC
>Mature Secondary Structure
MYIIAGLGNPGKEYMGTRHNAGFSVIDELADKYNISVDTAKHKGLIGKGVIAGQKVILVK
CEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHCCCEECHHHCCCCCCCEECCCEEEEEC
PMTYMNNSGECIREVMDYYKCDIDDFLVIFDDISLDVGKLRLRAKGSAGGHNGIKSIIAH
CHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHH
LGSDKFKRIKFGVGDKPKNWDLADWVLGKFPAEEYATLREANKKACEAVECILTDGIESG
HCCCHHEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNKYNG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA