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The map label for this gene is polC [H]

Identifier: 238917782

GI number: 238917782

Start: 1924841

End: 1925542

Strand: Reverse

Name: polC [H]

Synonym: EUBELI_01863

Alternate gene names: 238917782

Gene position: 1925542-1924841 (Counterclockwise)

Preceding gene: 238917783

Following gene: 238917780

Centisome position: 89.8

GC content: 37.89

Gene sequence:

>702_bases
ATGATTAACAGATATGTTGCACTGGATATTGAGACTACAGGTCTTAATCCGGCTGTTGACAGAATTATTGAAGTTGGAAT
GGCAAGAGTGGAAGATGGTCAGATAACACAGAAGTATTCTACGCTTGTGTATCCGGGAATAAGTGTAAGTGAGCGCATAA
CAGAGCTTACAGGCATACATAATGAGGAACTTACAGGTAAACCACGAATAGAGGATATTATAGGTGAAATAACAGAGTTC
ATAGGTGACTGGCCTGTATTAGGTCATAATGTTATATTTGATTTTAGTTTTCTTAAAAAGGCGGCAGTCAATAATGGTCT
TACTATCAATGATGATGGGATTGATACATTGAAGTTAGCCAGAAGGATTTTGCCGGAAGTGGAACACAAGAGTCTTTCCT
TTTTGTGCCAGTATTTTAATATAGATCCAGGCAGGTCACACAGAGCATACGATGATGCAGTCAGTGCAAGCCTGTTATAT
GCAAAGTTAGAAGAAATAAAGCCGGACGATGAAGGCTTTAGTAATACAACAAAACTTGTGTATACAGTGAAGAAGGATTC
ACCAATAACACTGCCACAGAAAAGATATCTCGCAGCACTTGTAGAAAAGCACAATATAAAGCTTGAGATTCCTATGGAAG
AAATGACTAAAAGCATGGCTTCAAGACAGATAGATACAATAATAGCACAGTATGGAAAATGA

Upstream 100 bases:

>100_bases
GGAAGATATAAGCTTGATAAGAAATGGGCAGAGAGCGACATGAATTTCCTTGCTATTATAGGTGATTACATAGGAAGAAT
ATTCCTGAAAGAGAGAAAAC

Downstream 100 bases:

>100_bases
TTCCACGCTGTGCTATTTTTTTAGTATGTCATCAAGCTGGCTGATTATTGAATCCCGGGAAAGGCTTTTTAATTGTGATG
CCTGTTCTTTTAAAGCGCTA

Product: DNA polymerase

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MINRYVALDIETTGLNPAVDRIIEVGMARVEDGQITQKYSTLVYPGISVSERITELTGIHNEELTGKPRIEDIIGEITEF
IGDWPVLGHNVIFDFSFLKKAAVNNGLTINDDGIDTLKLARRILPEVEHKSLSFLCQYFNIDPGRSHRAYDDAVSASLLY
AKLEEIKPDDEGFSNTTKLVYTVKKDSPITLPQKRYLAALVEKHNIKLEIPMEEMTKSMASRQIDTIIAQYGK

Sequences:

>Translated_233_residues
MINRYVALDIETTGLNPAVDRIIEVGMARVEDGQITQKYSTLVYPGISVSERITELTGIHNEELTGKPRIEDIIGEITEF
IGDWPVLGHNVIFDFSFLKKAAVNNGLTINDDGIDTLKLARRILPEVEHKSLSFLCQYFNIDPGRSHRAYDDAVSASLLY
AKLEEIKPDDEGFSNTTKLVYTVKKDSPITLPQKRYLAALVEKHNIKLEIPMEEMTKSMASRQIDTIIAQYGK
>Mature_233_residues
MINRYVALDIETTGLNPAVDRIIEVGMARVEDGQITQKYSTLVYPGISVSERITELTGIHNEELTGKPRIEDIIGEITEF
IGDWPVLGHNVIFDFSFLKKAAVNNGLTINDDGIDTLKLARRILPEVEHKSLSFLCQYFNIDPGRSHRAYDDAVSASLLY
AKLEEIKPDDEGFSNTTKLVYTVKKDSPITLPQKRYLAALVEKHNIKLEIPMEEMTKSMASRQIDTIIAQYGK

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26229; Mature: 26229

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRYVALDIETTGLNPAVDRIIEVGMARVEDGQITQKYSTLVYPGISVSERITELTGIH
CCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCHHHHHHHHHCCC
NEELTGKPRIEDIIGEITEFIGDWPVLGHNVIFDFSFLKKAAVNNGLTINDDGIDTLKLA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHHCCCCEECCCCCHHHHHH
RRILPEVEHKSLSFLCQYFNIDPGRSHRAYDDAVSASLLYAKLEEIKPDDEGFSNTTKLV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
YTVKKDSPITLPQKRYLAALVEKHNIKLEIPMEEMTKSMASRQIDTIIAQYGK
EEEECCCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINRYVALDIETTGLNPAVDRIIEVGMARVEDGQITQKYSTLVYPGISVSERITELTGIH
CCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCCHHHHHHHHHCCC
NEELTGKPRIEDIIGEITEFIGDWPVLGHNVIFDFSFLKKAAVNNGLTINDDGIDTLKLA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHHCCCCEECCCCCHHHHHH
RRILPEVEHKSLSFLCQYFNIDPGRSHRAYDDAVSASLLYAKLEEIKPDDEGFSNTTKLV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
YTVKKDSPITLPQKRYLAALVEKHNIKLEIPMEEMTKSMASRQIDTIIAQYGK
EEEECCCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]