Click here to switch to the map view.

The map label for this gene is yugH [H]

Identifier: 238917777

GI number: 238917777

Start: 1921354

End: 1922514

Strand: Reverse

Name: yugH [H]

Synonym: EUBELI_01858

Alternate gene names: 238917777

Gene position: 1922514-1921354 (Counterclockwise)

Preceding gene: 238917778

Following gene: 238917776

Centisome position: 89.66

GC content: 37.9

Gene sequence:

>1161_bases
ATGAGAAACCCATTATCACAGAAAATAACAGGTATACAGCCATCAGGAATAAGAAAGTTCTTTGATGTTGTAAGCGAGAT
GCCGGATGCTATTTCTTTAGGAGTAGGTGAACCTGATTTTGATACTCCCTGGAATGTAAGAGAAGAAGGTATATATGCCC
TTGAAAAAGGAAGAACATTTTACACATCTAATGCAGGTCTAAAGGAATTAAGAGAAGAGATATGTAATTATCTTGCGAGA
AAGATGGATTTACATTATGATCCTATCAAAGAAGTTCTTGTAACAGTAGGTGGAAGTGAGGCAATTGATGTTGCATTAAG
ATGTATGTGCGATCCGGGTGATGAGGTGCTTATTCCACAGCCTAGCTATGTATCATATCTTCCATGTGCAGTTATGGCTG
ATGCAAAGCCTGTAATTATTGAATTAAAGGAAGAAAACGAGTTTAAGCTTACTAAGGAAGAGCTGCTTGCCAGTATAACA
GATAAAACTAAAGTACTTGTTATGCCATTTCCTAATAATCCTACAGGTGCTGTTATGACAAGGGAGGAATTGGAAGAGCT
TGTACCTGTCATAATTGAGAAGGACATATTTGTTATATCGGATGAGATATATTCAGCTCTTACATATAACGGAGAGCATT
GTTCAATAGGAAGTCTTTCAGGGATGAAAGAGAGAACAATAGTAATTAATGGTTTTTCTAAGGCATTTGCAATGACAGGC
TGGAGACTGGGCTATGCATGTGGCCCTAAGGAAATAATAAGCCAGATGACTAAGCTTCATCAATATGCAATTATGTGCGC
ACCGACTAACAGCCAGTTTGCAGCAGTGGAGGCACTTAAGAATTGTGATATGGAAGTTGAGAAGATGGTTACTGCTTATG
ATCAGAGGCGAAGATATCTTATGCATGCTTTTAAAGAAATGGGGATTGATTGTTTTGAGCCATTTGGAGCATTTTATGTA
TTTCCATCAATCAAGAAATTTGGACTCACATCGGAAGAGTTTGCTAACAGGTTGCTTAGGGAACAGAAGCTGGCTGTAGT
GCCAGGAACAGCATTTGGAGACTGTGGAGAAGGGTTTTTACGAATATCATATGCATATTCTATTGACAATCTTAAAGAAG
GACTTGAGAGAATAGAGAAGTTTATCAATACACTTAAGTAA

Upstream 100 bases:

>100_bases
CAGTCCTTAGTACATCAACACATTTTGTACTTAAGAAATATAAGGACTACGGAACAATAATAGAGGACGAGGCTAAAGAC
GAAAGGATGCTGATTACACC

Downstream 100 bases:

>100_bases
GGAGAATAAGAAATATGGCAGAGATTAATGTTGACCATATCAATCCTTTTCTGATGGCAGCAAGTACAATTATGCGTGAT
GCCTGCCAGATGGAAATGAA

Product: hypothetical protein

Products: N-succinyl-2-L-amino-6-oxoheptanedioate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRNPLSQKITGIQPSGIRKFFDVVSEMPDAISLGVGEPDFDTPWNVREEGIYALEKGRTFYTSNAGLKELREEICNYLAR
KMDLHYDPIKEVLVTVGGSEAIDVALRCMCDPGDEVLIPQPSYVSYLPCAVMADAKPVIIELKEENEFKLTKEELLASIT
DKTKVLVMPFPNNPTGAVMTREELEELVPVIIEKDIFVISDEIYSALTYNGEHCSIGSLSGMKERTIVINGFSKAFAMTG
WRLGYACGPKEIISQMTKLHQYAIMCAPTNSQFAAVEALKNCDMEVEKMVTAYDQRRRYLMHAFKEMGIDCFEPFGAFYV
FPSIKKFGLTSEEFANRLLREQKLAVVPGTAFGDCGEGFLRISYAYSIDNLKEGLERIEKFINTLK

Sequences:

>Translated_386_residues
MRNPLSQKITGIQPSGIRKFFDVVSEMPDAISLGVGEPDFDTPWNVREEGIYALEKGRTFYTSNAGLKELREEICNYLAR
KMDLHYDPIKEVLVTVGGSEAIDVALRCMCDPGDEVLIPQPSYVSYLPCAVMADAKPVIIELKEENEFKLTKEELLASIT
DKTKVLVMPFPNNPTGAVMTREELEELVPVIIEKDIFVISDEIYSALTYNGEHCSIGSLSGMKERTIVINGFSKAFAMTG
WRLGYACGPKEIISQMTKLHQYAIMCAPTNSQFAAVEALKNCDMEVEKMVTAYDQRRRYLMHAFKEMGIDCFEPFGAFYV
FPSIKKFGLTSEEFANRLLREQKLAVVPGTAFGDCGEGFLRISYAYSIDNLKEGLERIEKFINTLK
>Mature_386_residues
MRNPLSQKITGIQPSGIRKFFDVVSEMPDAISLGVGEPDFDTPWNVREEGIYALEKGRTFYTSNAGLKELREEICNYLAR
KMDLHYDPIKEVLVTVGGSEAIDVALRCMCDPGDEVLIPQPSYVSYLPCAVMADAKPVIIELKEENEFKLTKEELLASIT
DKTKVLVMPFPNNPTGAVMTREELEELVPVIIEKDIFVISDEIYSALTYNGEHCSIGSLSGMKERTIVINGFSKAFAMTG
WRLGYACGPKEIISQMTKLHQYAIMCAPTNSQFAAVEALKNCDMEVEKMVTAYDQRRRYLMHAFKEMGIDCFEPFGAFYV
FPSIKKFGLTSEEFANRLLREQKLAVVPGTAFGDCGEGFLRISYAYSIDNLKEGLERIEKFINTLK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=379, Percent_Identity=29.5514511873351, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI169881279, Length=379, Percent_Identity=29.5514511873351, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI56713256, Length=376, Percent_Identity=27.9255319148936, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI56713254, Length=376, Percent_Identity=27.9255319148936, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI169881281, Length=267, Percent_Identity=29.2134831460674, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4507369, Length=394, Percent_Identity=24.8730964467005, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI215599424, Length=374, Percent_Identity=25.1336898395722, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI19263340, Length=375, Percent_Identity=26.1333333333333, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI187936925, Length=385, Percent_Identity=24.4155844155844, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI14211921, Length=385, Percent_Identity=24.4155844155844, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI7705897, Length=394, Percent_Identity=22.3350253807107, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI33469970, Length=394, Percent_Identity=22.3350253807107, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI149944424, Length=365, Percent_Identity=25.2054794520548, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788722, Length=355, Percent_Identity=29.2957746478873, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786816, Length=365, Percent_Identity=26.8493150684932, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788627, Length=371, Percent_Identity=29.3800539083558, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788332, Length=230, Percent_Identity=27.3913043478261, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=29.5918367346939, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=29.5918367346939, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17567369, Length=361, Percent_Identity=28.2548476454294, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=397, Percent_Identity=23.1738035264484, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981209, Length=339, Percent_Identity=24.188790560472, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=335, Percent_Identity=27.1641791044776, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=338, Percent_Identity=24.8520710059172, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=367, Percent_Identity=25.3405994550409, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=25.9708737864078, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=25.9708737864078, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=25.9708737864078, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=25.9708737864078, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24641770, Length=369, Percent_Identity=28.1842818428184, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641760, Length=369, Percent_Identity=28.1842818428184, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641768, Length=369, Percent_Identity=28.1842818428184, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641766, Length=369, Percent_Identity=28.1842818428184, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641764, Length=369, Percent_Identity=28.1842818428184, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI45551451, Length=369, Percent_Identity=28.1842818428184, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=24.3386243386243, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.17

Molecular weight: Translated: 43394; Mature: 43394

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNPLSQKITGIQPSGIRKFFDVVSEMPDAISLGVGEPDFDTPWNVREEGIYALEKGRTF
CCCCHHHHHCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCEE
YTSNAGLKELREEICNYLARKMDLHYDPIKEVLVTVGGSEAIDVALRCMCDPGDEVLIPQ
EECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECC
PSYVSYLPCAVMADAKPVIIELKEENEFKLTKEELLASITDKTKVLVMPFPNNPTGAVMT
CCCHHHCCHHHCCCCCCEEEEEECCCCCEECHHHHHHHHCCCCEEEEEECCCCCCCCEEE
REELEELVPVIIEKDIFVISDEIYSALTYNGEHCSIGSLSGMKERTIVINGFSKAFAMTG
HHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCC
WRLGYACGPKEIISQMTKLHQYAIMCAPTNSQFAAVEALKNCDMEVEKMVTAYDQRRRYL
CEECCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MHAFKEMGIDCFEPFGAFYVFPSIKKFGLTSEEFANRLLREQKLAVVPGTAFGDCGEGFL
HHHHHHCCCHHHCCCCCEEECCCHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCEE
RISYAYSIDNLKEGLERIEKFINTLK
EEEEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNPLSQKITGIQPSGIRKFFDVVSEMPDAISLGVGEPDFDTPWNVREEGIYALEKGRTF
CCCCHHHHHCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCEE
YTSNAGLKELREEICNYLARKMDLHYDPIKEVLVTVGGSEAIDVALRCMCDPGDEVLIPQ
EECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEECC
PSYVSYLPCAVMADAKPVIIELKEENEFKLTKEELLASITDKTKVLVMPFPNNPTGAVMT
CCCHHHCCHHHCCCCCCEEEEEECCCCCEECHHHHHHHHCCCCEEEEEECCCCCCCCEEE
REELEELVPVIIEKDIFVISDEIYSALTYNGEHCSIGSLSGMKERTIVINGFSKAFAMTG
HHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCC
WRLGYACGPKEIISQMTKLHQYAIMCAPTNSQFAAVEALKNCDMEVEKMVTAYDQRRRYL
CEECCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MHAFKEMGIDCFEPFGAFYVFPSIKKFGLTSEEFANRLLREQKLAVVPGTAFGDCGEGFL
HHHHHHCCCHHHCCCCCEEECCCHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCEE
RISYAYSIDNLKEGLERIEKFINTLK
EEEEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-succinyl-L-2,6-diaminoheptanedioate; 2-oxoglutarate

Specific reaction: N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-succinyl-2-L-amino-6-oxoheptanedioate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]