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The map label for this gene is ygcA [C]

Identifier: 238917769

GI number: 238917769

Start: 1911939

End: 1913393

Strand: Reverse

Name: ygcA [C]

Synonym: EUBELI_01850

Alternate gene names: 238917769

Gene position: 1913393-1911939 (Counterclockwise)

Preceding gene: 238917770

Following gene: 238917767

Centisome position: 89.24

GC content: 43.71

Gene sequence:

>1455_bases
ATGAGTTTTAAGAAAGATGATAAAGTAACATTTGTAATAGAAGATATAGGAACCGGAGGAGAGGGTATCGGCAAGGTTGA
CGGATATACTCTCTTTGTTAAGGATGCGATAATCGGAGATAAGATTGAGGCAAAGATTATTAAAGCCAAGAAGAATTACG
GCTATGCAAGGCTTGAAAAGATTATCGAGGCTTCATCTGACAGAGTGACTCCTGCCTGTCTTGTTGCGAGACAGTGCGGT
GGCTGTCAGATTCAGCAGATGAGTTATCAGGCACAGCTAAGATTTAAGGAAAAGCTGGTTGACGATAATCTCAAGCGAAT
CGGTAAGATAGAAGGCTATGAGTTTTTCCCGGCTATCGGAATGGAAGAGCCTTTCAGATACAGAAATAAAGCACAGTATC
CGGTTGGAACTGCCAAAGATGGAAGCGTTGTGATGGGCTTCTATGCAGGAAGAACTCATTCTATTATCTCATGTACAGAC
TGCAAGATTGGTGCTGTCGAGAACCAATATATTCTTGCTGTGATAAAGAGCTGGATGGAGCTCAACGGTGTTGCACCATA
TGATGAACAGACCAGAAAAGGGCTTGTGCGTCATGTCCTTATAAGAACAGGCTTTCACACAGACGAGATAATGGTCTGTC
TTGTTATTAACGGCACCAAGATGTCTGATAAGTTAAAGGAATCGCTTGTAGGGCGCCTTACAGAAGTGTCGCTTGATTCA
GATATAAGTACAGACAAATGCATCAAATCAATTATGCTTAATTACAACACGGAGAACACTAATGTCATTCTTGGCAGACA
GTGCGAGACTCTGTGGGGAAAAAGTTATATTGAAGATTATATCGGTGACATTAAGTATCAGATATCACCGCTTTCGTTCT
TTCAGGTTAATCCAAGACAGACTGAGAAGTTGTACGGAAAAGCCCTTGAATACGCAGGACTTACAGGCAATGAGACTGTA
TGGGACTTGTATTGTGGAATAGGAACAATATCGTTATTCCTTGCCAAGAATGCAAGAAAGGTATATGGTGTTGAGATTGT
TCCGCAAGCCATAGAAGATGCTAAGAACAATGCGGCAATTAACGGCATTGATAATGCTGAATTCTTTGTCGGAAAGGCTG
AGGAGGTCGTACCACATTTTTATGAAGAAATGGCGCGGCTGGCAACAGACACATCTGCAACAGAGGCTCAGCGTGAGGAA
GCAAGAAAGAGCATTACTCCTGATGTCGTAGTCGTTGACCCGCCAAGAAAGGGCTGCGATGAGTCGCTTCTTGACACGAT
TGTCAAGATGTCGCCTGAGCGTATCGTGTATGTAAGCTGCGATTCGGCAACACTCGCCCGTGACTTAGGACTCCTTGCGG
CTAAGGGTTACAAGACTGTTAAGGTACAGCCTGTGGACCAGTTTTCGCATACGGTGCACGTTGAATGTGTGTGCCTTTTG
GTTCGGATGGAATAA

Upstream 100 bases:

>100_bases
GCAAAGCTTGAGACACTAAGAGAAGCGCTTGAAGCCAAGGATACCAACGACTGGCTTGGTTATAACAGATGGCTTGATTC
TAATATAAGAAGGACAACTA

Downstream 100 bases:

>100_bases
TTTCATAAGCTTATATGGAGCATATATGAAGTATATATGGAGCGTGTCAGCCCGAAATGTTTTATAGATGGGTTGGTACG
CTCCTTTTTGGACGTCTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSFKKDDKVTFVIEDIGTGGEGIGKVDGYTLFVKDAIIGDKIEAKIIKAKKNYGYARLEKIIEASSDRVTPACLVARQCG
GCQIQQMSYQAQLRFKEKLVDDNLKRIGKIEGYEFFPAIGMEEPFRYRNKAQYPVGTAKDGSVVMGFYAGRTHSIISCTD
CKIGAVENQYILAVIKSWMELNGVAPYDEQTRKGLVRHVLIRTGFHTDEIMVCLVINGTKMSDKLKESLVGRLTEVSLDS
DISTDKCIKSIMLNYNTENTNVILGRQCETLWGKSYIEDYIGDIKYQISPLSFFQVNPRQTEKLYGKALEYAGLTGNETV
WDLYCGIGTISLFLAKNARKVYGVEIVPQAIEDAKNNAAINGIDNAEFFVGKAEEVVPHFYEEMARLATDTSATEAQREE
ARKSITPDVVVVDPPRKGCDESLLDTIVKMSPERIVYVSCDSATLARDLGLLAAKGYKTVKVQPVDQFSHTVHVECVCLL
VRME

Sequences:

>Translated_484_residues
MSFKKDDKVTFVIEDIGTGGEGIGKVDGYTLFVKDAIIGDKIEAKIIKAKKNYGYARLEKIIEASSDRVTPACLVARQCG
GCQIQQMSYQAQLRFKEKLVDDNLKRIGKIEGYEFFPAIGMEEPFRYRNKAQYPVGTAKDGSVVMGFYAGRTHSIISCTD
CKIGAVENQYILAVIKSWMELNGVAPYDEQTRKGLVRHVLIRTGFHTDEIMVCLVINGTKMSDKLKESLVGRLTEVSLDS
DISTDKCIKSIMLNYNTENTNVILGRQCETLWGKSYIEDYIGDIKYQISPLSFFQVNPRQTEKLYGKALEYAGLTGNETV
WDLYCGIGTISLFLAKNARKVYGVEIVPQAIEDAKNNAAINGIDNAEFFVGKAEEVVPHFYEEMARLATDTSATEAQREE
ARKSITPDVVVVDPPRKGCDESLLDTIVKMSPERIVYVSCDSATLARDLGLLAAKGYKTVKVQPVDQFSHTVHVECVCLL
VRME
>Mature_483_residues
SFKKDDKVTFVIEDIGTGGEGIGKVDGYTLFVKDAIIGDKIEAKIIKAKKNYGYARLEKIIEASSDRVTPACLVARQCGG
CQIQQMSYQAQLRFKEKLVDDNLKRIGKIEGYEFFPAIGMEEPFRYRNKAQYPVGTAKDGSVVMGFYAGRTHSIISCTDC
KIGAVENQYILAVIKSWMELNGVAPYDEQTRKGLVRHVLIRTGFHTDEIMVCLVINGTKMSDKLKESLVGRLTEVSLDSD
ISTDKCIKSIMLNYNTENTNVILGRQCETLWGKSYIEDYIGDIKYQISPLSFFQVNPRQTEKLYGKALEYAGLTGNETVW
DLYCGIGTISLFLAKNARKVYGVEIVPQAIEDAKNNAAINGIDNAEFFVGKAEEVVPHFYEEMARLATDTSATEAQREEA
RKSITPDVVVVDPPRKGCDESLLDTIVKMSPERIVYVSCDSATLARDLGLLAAKGYKTVKVQPVDQFSHTVHVECVCLLV
RME

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=376, Percent_Identity=28.7234042553192, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI51173878, Length=376, Percent_Identity=28.7234042553192, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI269784678, Length=382, Percent_Identity=26.1780104712042, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI269784680, Length=382, Percent_Identity=26.1780104712042, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI269784676, Length=382, Percent_Identity=26.1780104712042, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI20149688, Length=382, Percent_Identity=26.1780104712042, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789148, Length=477, Percent_Identity=27.4633123689727, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1787083, Length=366, Percent_Identity=24.8633879781421, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790403, Length=237, Percent_Identity=32.0675105485232, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322909, Length=170, Percent_Identity=32.3529411764706, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666579, Length=434, Percent_Identity=29.2626728110599, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 53939; Mature: 53807

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKKDDKVTFVIEDIGTGGEGIGKVDGYTLFVKDAIIGDKIEAKIIKAKKNYGYARLEK
CCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHEEEEEECCCCCHHHHHH
IIEASSDRVTPACLVARQCGGCQIQQMSYQAQLRFKEKLVDDNLKRIGKIEGYEFFPAIG
HHHCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
MEEPFRYRNKAQYPVGTAKDGSVVMGFYAGRTHSIISCTDCKIGAVENQYILAVIKSWME
CCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCEECCCCCHHHHHHHHHHHH
LNGVAPYDEQTRKGLVRHVLIRTGFHTDEIMVCLVINGTKMSDKLKESLVGRLTEVSLDS
HCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
DISTDKCIKSIMLNYNTENTNVILGRQCETLWGKSYIEDYIGDIKYQISPLSFFQVNPRQ
CCCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEECCEEEEEECCHH
TEKLYGKALEYAGLTGNETVWDLYCGIGTISLFLAKNARKVYGVEIVPQAIEDAKNNAAI
HHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEECHHHHHCCCCCCEE
NGIDNAEFFVGKAEEVVPHFYEEMARLATDTSATEAQREEARKSITPDVVVVDPPRKGCD
CCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
ESLLDTIVKMSPERIVYVSCDSATLARDLGLLAAKGYKTVKVQPVDQFSHTVHVECVCLL
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEHHHCCCEEEEEEEEEE
VRME
EECC
>Mature Secondary Structure 
SFKKDDKVTFVIEDIGTGGEGIGKVDGYTLFVKDAIIGDKIEAKIIKAKKNYGYARLEK
CCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHEEEEEECCCCCHHHHHH
IIEASSDRVTPACLVARQCGGCQIQQMSYQAQLRFKEKLVDDNLKRIGKIEGYEFFPAIG
HHHCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
MEEPFRYRNKAQYPVGTAKDGSVVMGFYAGRTHSIISCTDCKIGAVENQYILAVIKSWME
CCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCEECCCCCHHHHHHHHHHHH
LNGVAPYDEQTRKGLVRHVLIRTGFHTDEIMVCLVINGTKMSDKLKESLVGRLTEVSLDS
HCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
DISTDKCIKSIMLNYNTENTNVILGRQCETLWGKSYIEDYIGDIKYQISPLSFFQVNPRQ
CCCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEECCEEEEEECCHH
TEKLYGKALEYAGLTGNETVWDLYCGIGTISLFLAKNARKVYGVEIVPQAIEDAKNNAAI
HHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEECHHHHHCCCCCCEE
NGIDNAEFFVGKAEEVVPHFYEEMARLATDTSATEAQREEARKSITPDVVVVDPPRKGCD
CCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
ESLLDTIVKMSPERIVYVSCDSATLARDLGLLAAKGYKTVKVQPVDQFSHTVHVECVCLL
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEHHHCCCEEEEEEEEEE
VRME
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]