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The map label for this gene is luxS [H]

Identifier: 238917755

GI number: 238917755

Start: 1896093

End: 1896578

Strand: Reverse

Name: luxS [H]

Synonym: EUBELI_01836

Alternate gene names: 238917755

Gene position: 1896578-1896093 (Counterclockwise)

Preceding gene: 238917756

Following gene: 238917751

Centisome position: 88.45

GC content: 36.42

Gene sequence:

>486_bases
ATGAACAAGATAGCAAGTTTTACGGTGAATCATCTTGATTTACTGACAGGTGTATATGTATCAAGAAAGGATTATATCGG
AGATGTATGTCTTACAACATTTGATTTAAGATTTACAAGACCTAATGAAGAGCCACCTATGGATACTCCGGGGATTCATT
CAATTGAACATCTTGTTGCTACATTTTTAAGAAATCATGCAGAATGGGCTGAGAAAACTATATATTTCGGACCTATGGGC
TGCAGAACAGGTTTTTATGTTATATTTGCAGGAGATTTAAAGTCAGAGGATATTATCGGGATATTAAGAGAAGCTGCCGA
CTATGTTCTTAATTATGACGATAATACACCAATTCCTGGATATTCACCAAGAGACTGTGGTAATTATCTGGATAACAATC
TTAAGCTTGCGAAGATATATATGAGGAAGTTTAAGGAGGAGGTTCTGGATAATCCGGTTGAGGAGAGGTTGAGTTATCCA
CAGTAG

Upstream 100 bases:

>100_bases
GATATTCAACTCTGACAAAATTTGTATCAAGCATAAAAGAACTGCTAATAGAAACAACAGATAACAAAAGAATAGTATTT
ATAAGAAAGAAGGAGTCATA

Downstream 100 bases:

>100_bases
CGTGTAGGTGGTGCCAGTCTGGGGATATCGGGCTGTGGCTTTCATGGATTACTCCTGCACAACTCGTAATAAATCAAGCC
ACAGCCCGATACCCCCAGAC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MNKIASFTVNHLDLLTGVYVSRKDYIGDVCLTTFDLRFTRPNEEPPMDTPGIHSIEHLVATFLRNHAEWAEKTIYFGPMG
CRTGFYVIFAGDLKSEDIIGILREAADYVLNYDDNTPIPGYSPRDCGNYLDNNLKLAKIYMRKFKEEVLDNPVEERLSYP
Q

Sequences:

>Translated_161_residues
MNKIASFTVNHLDLLTGVYVSRKDYIGDVCLTTFDLRFTRPNEEPPMDTPGIHSIEHLVATFLRNHAEWAEKTIYFGPMG
CRTGFYVIFAGDLKSEDIIGILREAADYVLNYDDNTPIPGYSPRDCGNYLDNNLKLAKIYMRKFKEEVLDNPVEERLSYP
Q
>Mature_161_residues
MNKIASFTVNHLDLLTGVYVSRKDYIGDVCLTTFDLRFTRPNEEPPMDTPGIHSIEHLVATFLRNHAEWAEKTIYFGPMG
CRTGFYVIFAGDLKSEDIIGILREAADYVLNYDDNTPIPGYSPRDCGNYLDNNLKLAKIYMRKFKEEVLDNPVEERLSYP
Q

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=160, Percent_Identity=35.625, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18491; Mature: 18491

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIASFTVNHLDLLTGVYVSRKDYIGDVCLTTFDLRFTRPNEEPPMDTPGIHSIEHLVA
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHH
TFLRNHAEWAEKTIYFGPMGCRTGFYVIFAGDLKSEDIIGILREAADYVLNYDDNTPIPG
HHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCCCCC
YSPRDCGNYLDNNLKLAKIYMRKFKEEVLDNPVEERLSYPQ
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure
MNKIASFTVNHLDLLTGVYVSRKDYIGDVCLTTFDLRFTRPNEEPPMDTPGIHSIEHLVA
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHH
TFLRNHAEWAEKTIYFGPMGCRTGFYVIFAGDLKSEDIIGILREAADYVLNYDDNTPIPG
HHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCCCCC
YSPRDCGNYLDNNLKLAKIYMRKFKEEVLDNPVEERLSYPQ
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]