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The map label for this gene is yoeA [H]

Identifier: 238917652

GI number: 238917652

Start: 1797048

End: 1798403

Strand: Reverse

Name: yoeA [H]

Synonym: EUBELI_01731

Alternate gene names: 238917652

Gene position: 1798403-1797048 (Counterclockwise)

Preceding gene: 238917653

Following gene: 238917650

Centisome position: 83.87

GC content: 38.27

Gene sequence:

>1356_bases
ATGAGTAAGAATAAATACGAAATAGATATGTGCAATGGCACAATAATGGACAAGTTAATATCGTTTTCAGTGCCATTGAT
GCTTTCAGGAATACTACAGCTAATGTTTAATGCTGTAGATATAATTGTTGTTGGAAGATTTGCAGGAAGCCAGTCGTTAG
CAGCAGTAGGTTCAACGACAGCGCTTATTAATATGTTTGTTAATCTTTTCATAGGAGTTTCTTTGGGAGCAAATGTACTG
GCTGCCAGATTCTATGCGTCAGGCAAACATAAAGAGATGTCAGAGACAGTGCATACTGCGATAACATTTGCAGCAATAAG
CGGAGTTGTGATGGCGCTGATAGGCGTGCTGATGGCTAAGCCGGCACTTGAGCTTATGGGAACACCGGATGATGTAATTA
ATCTCTCAACACTGTATATGAGAATATATTTTCTTGGTATGCCATTCTTTATGCTTTATAACTATGGTGCGGCTGTTCTT
AGAGCAGTTGGTGATACCAAGAGACCGCTGATGTTTCTTATGGCAGCGGGAATCATAAATGCATGCCTTAATATGGTACT
TGTTATTGTGTTTAACTTAGGGGTTGCAGGAGTGGCAATCGCAACAATATTTTCACAGTTTATATCGTGTGTGCTTGTAT
TAAGATGTCTGAATAAGACAGATGCAAGTTACCAGTTGAGATTCTCAAAGCTAAAGATAAAGGGATACTATCTTAAACAG
ATATTTCAGGTTGGAATTCCGGCAGGAATACAGAGTACAGTTATTAATTTCTCAAATGCTTTGCTGCAGTCGTCGGTTAA
TTCATTCGGTTCAACAGCAATGGCAGGATATACAGCAGCCAACAATATTCTTGGCTTTCTATATGCATCAATTAATTCAG
TAACACAGGCCTGCATGAGTTTTACAAGTCAGAATTATGGTGTAAGAAAGTTCAAGAGAATGGACAAGGTGCTTATAGAT
TGTGCAATACTTTCGGTAGGAGCATCACTTGTATTTGGATGCGGTGCATATATATTTGGTGATAAAGTGCTTATGATATA
CACTAACAGTGAAGATGTTATCAAATGTGGTGTTGAGATATTATCAATTACTACAGTACCATATTTCTTATGTGGAATAA
TGGATCTGTTTCCGGGCGCGCTTCGTGGAATGGGGTATTCGCTAGTACCTATGATATTATCAGTTATTGGTACAGTAGGA
ATGAGAATATTCTGGATATTCGTCATATTCCCAAGTCACAGAACACTTTATGACCTGTTCATATCATATCCGGCATCATG
GACGGCAACGATAATTATGCAGGTTATATGTTTCCTTGTAGTACGTCGAAAAGTGCATTCACAGATTAATAAATGA

Upstream 100 bases:

>100_bases
TTTAATGCATATGGATATTATGCTAAGGGGCTTGGTTTATATCAGAAGGGTGTTGAACTGGGTTACTGGGAATAAGGATG
CTTCATGAGGGAATGCGGTA

Downstream 100 bases:

>100_bases
TTATAAAATATTTAAGCCATTCCGGAAGGAGTGGCTTATTAACTATAAAGTTCTTCAAGAGTCCTGGCTATCTCGCCAGC
ATCACAGTCACATCCGTTTT

Product: MATE family multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSKNKYEIDMCNGTIMDKLISFSVPLMLSGILQLMFNAVDIIVVGRFAGSQSLAAVGSTTALINMFVNLFIGVSLGANVL
AARFYASGKHKEMSETVHTAITFAAISGVVMALIGVLMAKPALELMGTPDDVINLSTLYMRIYFLGMPFFMLYNYGAAVL
RAVGDTKRPLMFLMAAGIINACLNMVLVIVFNLGVAGVAIATIFSQFISCVLVLRCLNKTDASYQLRFSKLKIKGYYLKQ
IFQVGIPAGIQSTVINFSNALLQSSVNSFGSTAMAGYTAANNILGFLYASINSVTQACMSFTSQNYGVRKFKRMDKVLID
CAILSVGASLVFGCGAYIFGDKVLMIYTNSEDVIKCGVEILSITTVPYFLCGIMDLFPGALRGMGYSLVPMILSVIGTVG
MRIFWIFVIFPSHRTLYDLFISYPASWTATIIMQVICFLVVRRKVHSQINK

Sequences:

>Translated_451_residues
MSKNKYEIDMCNGTIMDKLISFSVPLMLSGILQLMFNAVDIIVVGRFAGSQSLAAVGSTTALINMFVNLFIGVSLGANVL
AARFYASGKHKEMSETVHTAITFAAISGVVMALIGVLMAKPALELMGTPDDVINLSTLYMRIYFLGMPFFMLYNYGAAVL
RAVGDTKRPLMFLMAAGIINACLNMVLVIVFNLGVAGVAIATIFSQFISCVLVLRCLNKTDASYQLRFSKLKIKGYYLKQ
IFQVGIPAGIQSTVINFSNALLQSSVNSFGSTAMAGYTAANNILGFLYASINSVTQACMSFTSQNYGVRKFKRMDKVLID
CAILSVGASLVFGCGAYIFGDKVLMIYTNSEDVIKCGVEILSITTVPYFLCGIMDLFPGALRGMGYSLVPMILSVIGTVG
MRIFWIFVIFPSHRTLYDLFISYPASWTATIIMQVICFLVVRRKVHSQINK
>Mature_450_residues
SKNKYEIDMCNGTIMDKLISFSVPLMLSGILQLMFNAVDIIVVGRFAGSQSLAAVGSTTALINMFVNLFIGVSLGANVLA
ARFYASGKHKEMSETVHTAITFAAISGVVMALIGVLMAKPALELMGTPDDVINLSTLYMRIYFLGMPFFMLYNYGAAVLR
AVGDTKRPLMFLMAAGIINACLNMVLVIVFNLGVAGVAIATIFSQFISCVLVLRCLNKTDASYQLRFSKLKIKGYYLKQI
FQVGIPAGIQSTVINFSNALLQSSVNSFGSTAMAGYTAANNILGFLYASINSVTQACMSFTSQNYGVRKFKRMDKVLIDC
AILSVGASLVFGCGAYIFGDKVLMIYTNSEDVIKCGVEILSITTVPYFLCGIMDLFPGALRGMGYSLVPMILSVIGTVGM
RIFWIFVIFPSHRTLYDLFISYPASWTATIIMQVICFLVVRRKVHSQINK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI153792564, Length=383, Percent_Identity=26.1096605744125, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49188; Mature: 49057

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNKYEIDMCNGTIMDKLISFSVPLMLSGILQLMFNAVDIIVVGRFAGSQSLAAVGSTT
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHH
ALINMFVNLFIGVSLGANVLAARFYASGKHKEMSETVHTAITFAAISGVVMALIGVLMAK
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PALELMGTPDDVINLSTLYMRIYFLGMPFFMLYNYGAAVLRAVGDTKRPLMFLMAAGIIN
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ACLNMVLVIVFNLGVAGVAIATIFSQFISCVLVLRCLNKTDASYQLRFSKLKIKGYYLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHEEEHHHHHHH
IFQVGIPAGIQSTVINFSNALLQSSVNSFGSTAMAGYTAANNILGFLYASINSVTQACMS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTSQNYGVRKFKRMDKVLIDCAILSVGASLVFGCGAYIFGDKVLMIYTNSEDVIKCGVEI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEEEEEECCCHHHHHHHHH
LSITTVPYFLCGIMDLFPGALRGMGYSLVPMILSVIGTVGMRIFWIFVIFPSHRTLYDLF
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHH
ISYPASWTATIIMQVICFLVVRRKVHSQINK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKNKYEIDMCNGTIMDKLISFSVPLMLSGILQLMFNAVDIIVVGRFAGSQSLAAVGSTT
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHH
ALINMFVNLFIGVSLGANVLAARFYASGKHKEMSETVHTAITFAAISGVVMALIGVLMAK
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PALELMGTPDDVINLSTLYMRIYFLGMPFFMLYNYGAAVLRAVGDTKRPLMFLMAAGIIN
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ACLNMVLVIVFNLGVAGVAIATIFSQFISCVLVLRCLNKTDASYQLRFSKLKIKGYYLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHEEEHHHHHHH
IFQVGIPAGIQSTVINFSNALLQSSVNSFGSTAMAGYTAANNILGFLYASINSVTQACMS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTSQNYGVRKFKRMDKVLIDCAILSVGASLVFGCGAYIFGDKVLMIYTNSEDVIKCGVEI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEEEEEECCCHHHHHHHHH
LSITTVPYFLCGIMDLFPGALRGMGYSLVPMILSVIGTVGMRIFWIFVIFPSHRTLYDLF
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHH
ISYPASWTATIIMQVICFLVVRRKVHSQINK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]