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The map label for this gene is yesM [H]

Identifier: 238917631

GI number: 238917631

Start: 1776900

End: 1778657

Strand: Reverse

Name: yesM [H]

Synonym: EUBELI_01710

Alternate gene names: 238917631

Gene position: 1778657-1776900 (Counterclockwise)

Preceding gene: 238917632

Following gene: 238917630

Centisome position: 82.95

GC content: 37.71

Gene sequence:

>1758_bases
TTGAAAAAGATTAAGCAGAAAATCAATGATATAAGATTGCAGAACAAGCTTGTCATCATATATGTAGTGACCGGACTTAT
TCCCCTGATTGTGCTTTTTGTTTTTGCATACTGTCAGATGAGAAACATTCTTATGGACAGGGACTTAAAGAGCATCAAGG
GGACAATTGAACAGTCTGTTACAACGGTGGATGGGCAGATAGAGGTGTATGATAATCTGTCTAATTATATAACATTTAAT
GATACGCTGTCGGGAGTGCTTTCATACGATTACAAAAGCACATATGAGATGTATAACCAGATTGTCACTACATTTGACCC
TATGCTTTCATCATTAAAGTATTTTCACAATGATATTAACAGAGTAACAATATATGTGGATAAAGCTATTAAACATGATA
CGACTATAGCTCCAATAGAAGAGATAAAAGACAGACCTTTTTATAATTCTGCTGCTGAAAGCACTAAGATACAGTGGTTT
GTTGATGAAGACAGCAGGACACTTGTTTCAGCACGAAAAATGTCAACGCTTGACCAGTTAGGAATTCTTGGAATCATGTA
CATAGATGTTGATTATGACAGCATGATGAGTTCATTTACAGGTGGTCTTGAGCAGAACTGCGGAATGGTGGTGCTTGACG
CTGATGGAAAAGTTATATGCAGCAGTGACACATTTGAAAACAATAACACCAGATACAGATTAAACAGCAAGAAACTGCTT
TCGTTAATCGACGGGGCAGAATGGGATAATGATACATGTGGAAATACAGAGGGTTATTCTGTAGTAAAGAAGGAAAGCTC
TGTTACCGGATGGACAGTATATGTCTATGAACCAAGAAAACTTGTGCTCAGGTCAGCTAATTCAATGATTACAATGATTG
TAGTTGCATTTGTGGTAGCAGTTGCAGGTGCCGCTGCGGCGAGTATATTTACAACAGGCTTCATTACAAGAAGAATTAAT
AAATTAAAAAACAGTATGGCAAAGGTTGAAAATGGAGACTTTGATGCGGTAATTAATACACAGGACAAAGATGAAATAGG
TGACCTTATTCATAGCTTTAACAGCATGACAACCCAGATTAAGAATCTTATCACGCAGGTATATGAAGGACGTATAAGCC
AGAAAGAATCAGAGATGCGGGCATTAAGGGCACAGATTAATCCGCATTTTCTCTACAATTCATTATCGCTTATCAACTGG
AAAGCAATAGAATATGAGCAGGAGGATATAAGTGAGATAACACTTGCATTGTCTAACTACTACCGTACATCGCTTAATAA
GGGAAAGAATATACTAAGCTTTGAGCAGGAATTAAGCAACATGCAGTCGTATCTTAAGATTCAGCAGATAATGCATGACA
ACTCATTTGATGTGGTGATAAATGTATCAGAGGAAGTTATGCCATGCGAATCTTTAAACCTTATACTCCAGCCATTGGTA
GAAAATGCAATAGACCACGGTATAGATCTGCTGACAGACAGGAAAGGTGTAATAACAGTAGAGGCCAAGATGCAGACGGA
TGAAGAAGGTAAAAAGCTTGTATGTGTAACAGTGTCTGATAACGGTGTAGGAATGGACAAAGAAACTGCACAAAACTTCT
TAACAGTCCAGTCAAAAGGGTATGGTGCAAGAAATGTTAATGACAGAATAAGACTTTATTACGGCGAAAGCTATCATCTG
GAAGTGCAGAGCATACCTGATGAGGGAACAACAATAACAATAAAATTCCCGGCAAAACCATACAACACAAAAAACTGA

Upstream 100 bases:

>100_bases
GTGAGCAGGTGGGTTATCCAAATGTTTCATATTTTGTACAGAGCTTCAGGGAGTACTTTGGTATAAGTCCTCAGAAATTC
AGGGATCAGGGAGAATTGAG

Downstream 100 bases:

>100_bases
TATGTTTCTAAAATATCTTATATTTTAATATTAACCCCTCCTTAATATAATTAGATTATCAAAAGAGGACAGTAATCAAA
GCTGTCTCGGATAATTATTA

Product: two-component system sensor histidine kinase YesM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MKKIKQKINDIRLQNKLVIIYVVTGLIPLIVLFVFAYCQMRNILMDRDLKSIKGTIEQSVTTVDGQIEVYDNLSNYITFN
DTLSGVLSYDYKSTYEMYNQIVTTFDPMLSSLKYFHNDINRVTIYVDKAIKHDTTIAPIEEIKDRPFYNSAAESTKIQWF
VDEDSRTLVSARKMSTLDQLGILGIMYIDVDYDSMMSSFTGGLEQNCGMVVLDADGKVICSSDTFENNNTRYRLNSKKLL
SLIDGAEWDNDTCGNTEGYSVVKKESSVTGWTVYVYEPRKLVLRSANSMITMIVVAFVVAVAGAAAASIFTTGFITRRIN
KLKNSMAKVENGDFDAVINTQDKDEIGDLIHSFNSMTTQIKNLITQVYEGRISQKESEMRALRAQINPHFLYNSLSLINW
KAIEYEQEDISEITLALSNYYRTSLNKGKNILSFEQELSNMQSYLKIQQIMHDNSFDVVINVSEEVMPCESLNLILQPLV
ENAIDHGIDLLTDRKGVITVEAKMQTDEEGKKLVCVTVSDNGVGMDKETAQNFLTVQSKGYGARNVNDRIRLYYGESYHL
EVQSIPDEGTTITIKFPAKPYNTKN

Sequences:

>Translated_585_residues
MKKIKQKINDIRLQNKLVIIYVVTGLIPLIVLFVFAYCQMRNILMDRDLKSIKGTIEQSVTTVDGQIEVYDNLSNYITFN
DTLSGVLSYDYKSTYEMYNQIVTTFDPMLSSLKYFHNDINRVTIYVDKAIKHDTTIAPIEEIKDRPFYNSAAESTKIQWF
VDEDSRTLVSARKMSTLDQLGILGIMYIDVDYDSMMSSFTGGLEQNCGMVVLDADGKVICSSDTFENNNTRYRLNSKKLL
SLIDGAEWDNDTCGNTEGYSVVKKESSVTGWTVYVYEPRKLVLRSANSMITMIVVAFVVAVAGAAAASIFTTGFITRRIN
KLKNSMAKVENGDFDAVINTQDKDEIGDLIHSFNSMTTQIKNLITQVYEGRISQKESEMRALRAQINPHFLYNSLSLINW
KAIEYEQEDISEITLALSNYYRTSLNKGKNILSFEQELSNMQSYLKIQQIMHDNSFDVVINVSEEVMPCESLNLILQPLV
ENAIDHGIDLLTDRKGVITVEAKMQTDEEGKKLVCVTVSDNGVGMDKETAQNFLTVQSKGYGARNVNDRIRLYYGESYHL
EVQSIPDEGTTITIKFPAKPYNTKN
>Mature_585_residues
MKKIKQKINDIRLQNKLVIIYVVTGLIPLIVLFVFAYCQMRNILMDRDLKSIKGTIEQSVTTVDGQIEVYDNLSNYITFN
DTLSGVLSYDYKSTYEMYNQIVTTFDPMLSSLKYFHNDINRVTIYVDKAIKHDTTIAPIEEIKDRPFYNSAAESTKIQWF
VDEDSRTLVSARKMSTLDQLGILGIMYIDVDYDSMMSSFTGGLEQNCGMVVLDADGKVICSSDTFENNNTRYRLNSKKLL
SLIDGAEWDNDTCGNTEGYSVVKKESSVTGWTVYVYEPRKLVLRSANSMITMIVVAFVVAVAGAAAASIFTTGFITRRIN
KLKNSMAKVENGDFDAVINTQDKDEIGDLIHSFNSMTTQIKNLITQVYEGRISQKESEMRALRAQINPHFLYNSLSLINW
KAIEYEQEDISEITLALSNYYRTSLNKGKNILSFEQELSNMQSYLKIQQIMHDNSFDVVINVSEEVMPCESLNLILQPLV
ENAIDHGIDLLTDRKGVITVEAKMQTDEEGKKLVCVTVSDNGVGMDKETAQNFLTVQSKGYGARNVNDRIRLYYGESYHL
EVQSIPDEGTTITIKFPAKPYNTKN

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=204, Percent_Identity=29.9019607843137, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788723, Length=235, Percent_Identity=31.4893617021277, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66256; Mature: 66256

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKQKINDIRLQNKLVIIYVVTGLIPLIVLFVFAYCQMRNILMDRDLKSIKGTIEQSV
CCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TTVDGQIEVYDNLSNYITFNDTLSGVLSYDYKSTYEMYNQIVTTFDPMLSSLKYFHNDIN
EEECCEEEEEECCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVTIYVDKAIKHDTTIAPIEEIKDRPFYNSAAESTKIQWFVDEDSRTLVSARKMSTLDQL
EEEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHC
GILGIMYIDVDYDSMMSSFTGGLEQNCGMVVLDADGKVICSSDTFENNNTRYRLNSKKLL
CCEEEEEEECCHHHHHHHHCCCCCCCCCEEEECCCCCEEECCCCCCCCCCEEEECHHHHH
SLIDGAEWDNDTCGNTEGYSVVKKESSVTGWTVYVYEPRKLVLRSANSMITMIVVAFVVA
HHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHH
VAGAAAASIFTTGFITRRINKLKNSMAKVENGDFDAVINTQDKDEIGDLIHSFNSMTTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
KNLITQVYEGRISQKESEMRALRAQINPHFLYNSLSLINWKAIEYEQEDISEITLALSNY
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHH
YRTSLNKGKNILSFEQELSNMQSYLKIQQIMHDNSFDVVINVSEEVMPCESLNLILQPLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCHHHHHHHHHHHH
ENAIDHGIDLLTDRKGVITVEAKMQTDEEGKKLVCVTVSDNGVGMDKETAQNFLTVQSKG
HHHHHCCCCEEECCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHEEEEECCC
YGARNVNDRIRLYYGESYHLEVQSIPDEGTTITIKFPAKPYNTKN
CCCCCCCCCEEEEECCEEEEEEEECCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKKIKQKINDIRLQNKLVIIYVVTGLIPLIVLFVFAYCQMRNILMDRDLKSIKGTIEQSV
CCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TTVDGQIEVYDNLSNYITFNDTLSGVLSYDYKSTYEMYNQIVTTFDPMLSSLKYFHNDIN
EEECCEEEEEECCCCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RVTIYVDKAIKHDTTIAPIEEIKDRPFYNSAAESTKIQWFVDEDSRTLVSARKMSTLDQL
EEEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHC
GILGIMYIDVDYDSMMSSFTGGLEQNCGMVVLDADGKVICSSDTFENNNTRYRLNSKKLL
CCEEEEEEECCHHHHHHHHCCCCCCCCCEEEECCCCCEEECCCCCCCCCCEEEECHHHHH
SLIDGAEWDNDTCGNTEGYSVVKKESSVTGWTVYVYEPRKLVLRSANSMITMIVVAFVVA
HHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHH
VAGAAAASIFTTGFITRRINKLKNSMAKVENGDFDAVINTQDKDEIGDLIHSFNSMTTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
KNLITQVYEGRISQKESEMRALRAQINPHFLYNSLSLINWKAIEYEQEDISEITLALSNY
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHH
YRTSLNKGKNILSFEQELSNMQSYLKIQQIMHDNSFDVVINVSEEVMPCESLNLILQPLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCHHHHHHHHHHHH
ENAIDHGIDLLTDRKGVITVEAKMQTDEEGKKLVCVTVSDNGVGMDKETAQNFLTVQSKG
HHHHHCCCCEEECCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHEEEEECCC
YGARNVNDRIRLYYGESYHLEVQSIPDEGTTITIKFPAKPYNTKN
CCCCCCCCCEEEEECCEEEEEEEECCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]