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The map label for this gene is arsC [H]

Identifier: 238917576

GI number: 238917576

Start: 1714979

End: 1715389

Strand: Reverse

Name: arsC [H]

Synonym: EUBELI_01655

Alternate gene names: 238917576

Gene position: 1715389-1714979 (Counterclockwise)

Preceding gene: 238917577

Following gene: 238917575

Centisome position: 80.0

GC content: 36.98

Gene sequence:

>411_bases
ATGAGTAAGATAAAAGTAGCTTTTATTTGTGTCCATAATTCCTGCCGAAGTCAGATTGCTGAGGCTTTTGGAAGACATAT
GGCATCAGATGTGTTTCAAAGTTATTCGGCGGGGACAGAAACAAAACCACGGATTAATCAGGATGCTGTCCGTATTATGA
AGGAATTATATAATATAGATATGGAAGCAGAAGGACAGTTCAGTAAGCTGGTTAGTGATATTCCAGAACCGGATATTGCA
ATATCAATGGGATGCAATGTAGGGTGTCCATTTATAGGCAGACCATTTGATGATAATTGGGGACTTGAAGATCCAACTGG
GAAAAGCGATGAGGAATTTAAGATAGTCATTGAACAAATAAAGCATGATATTTTGGAGTTAAAAAGTCGATTGAACCATA
ATGAGATTTAA

Upstream 100 bases:

>100_bases
TATGTAAATGCTCATTATGGAGTAACATTGCAATACGAACAAATGCAATGCGGATTCACAGATTTTAATGAGCAATGTAT
AAAGGAGAGGTGTCCATTTT

Downstream 100 bases:

>100_bases
TAAACTTTTTTGTCTGACTGAGAAAATTAATAATAAACTTACACAGCACTTTAGTCAGAGGATGGAGTAGTTATTTCGAA
AACGATGTACTAGGAATTGA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSKIKVAFICVHNSCRSQIAEAFGRHMASDVFQSYSAGTETKPRINQDAVRIMKELYNIDMEAEGQFSKLVSDIPEPDIA
ISMGCNVGCPFIGRPFDDNWGLEDPTGKSDEEFKIVIEQIKHDILELKSRLNHNEI

Sequences:

>Translated_136_residues
MSKIKVAFICVHNSCRSQIAEAFGRHMASDVFQSYSAGTETKPRINQDAVRIMKELYNIDMEAEGQFSKLVSDIPEPDIA
ISMGCNVGCPFIGRPFDDNWGLEDPTGKSDEEFKIVIEQIKHDILELKSRLNHNEI
>Mature_135_residues
SKIKVAFICVHNSCRSQIAEAFGRHMASDVFQSYSAGTETKPRINQDAVRIMKELYNIDMEAEGQFSKLVSDIPEPDIAI
SMGCNVGCPFIGRPFDDNWGLEDPTGKSDEEFKIVIEQIKHDILELKSRLNHNEI

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15348; Mature: 15216

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIKVAFICVHNSCRSQIAEAFGRHMASDVFQSYSAGTETKPRINQDAVRIMKELYNID
CCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
MEAEGQFSKLVSDIPEPDIAISMGCNVGCPFIGRPFDDNWGLEDPTGKSDEEFKIVIEQI
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KHDILELKSRLNHNEI
HHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKIKVAFICVHNSCRSQIAEAFGRHMASDVFQSYSAGTETKPRINQDAVRIMKELYNID
CCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
MEAEGQFSKLVSDIPEPDIAISMGCNVGCPFIGRPFDDNWGLEDPTGKSDEEFKIVIEQI
CCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
KHDILELKSRLNHNEI
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1534327 [H]