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The map label for this gene is typA [H]

Identifier: 238917512

GI number: 238917512

Start: 1642793

End: 1644622

Strand: Direct

Name: typA [H]

Synonym: EUBELI_01591

Alternate gene names: 238917512

Gene position: 1642793-1644622 (Clockwise)

Preceding gene: 238917508

Following gene: 238917513

Centisome position: 76.62

GC content: 39.62

Gene sequence:

>1830_bases
ATGAAAACAAAGCGTGATGATATTCGTAATATTGCAATTATTGCCCACGTTGATCATGGTAAGACAACCCTTGTTGATGA
GCTGTTGAAGCAGAGCGGAACTTTCAGAGCTAATCAGGAAGTCGCTGAACGAGTTATGGATTCCAATGATATCGAAAGAG
AAAGAGGAATCACTATTCTTTCTAAGAATACAGCTATCACATATAAGGATACTAAGATTAACATTATTGATACTCCTGGC
CATGCCGATTTTGGCGGTGAGGTTGAACGAGTACTTAAAATGGTTAACGGCGTTATTCTTGTTGTTGACGCATTCGAAGG
TGTTATGCCTCAGACTAAGTTCGTATTACAGAAAGCCCTTGATATGAATCTTTCTGTTATAGTATGTATTAACAAGATAG
ACAGACCAGAAGCAAGACCAGAAGAAGTTATCGATGAGATCTTAGAGCTTTTCATTGACCTTGATGCTAATGAAGATCAG
CTTGATTGTCCATTCATTTTTGCTTCAGCTAAGTCAGGCTATGCTATGGCAGACCTTAATGATGAAAAGAAAGACATGCA
GCCACTCTTCGACTGTATCGTCAATAACATTCCTGCACCAGAGGGTGACCCTGATGCAGATACACAGATGCTTATCTCTA
CTATTGACTACAACGAATTCGTTGGTAGAATTGGTGTAGGTAAGATTGATAATGGAAGCCTTAAGGTTAATCAAGAGGTT
ATGATTGTTAACCACCATGATCCAAGCGTTAAGAAGCGTGTAAGAATTACTAAGCTTTATACATTTAACGGACTTAATAA
GGTAGAAGTTAATGAAGCAGGAATCGGTGAAATTGTTGCTGTATCAGGTATTGCTGATATTCATATCGGTGATACAATCT
GTTCACTTAACAACCCTGTTGCCATTCCTTTCCAGAAGATTTCAGAGCCTACTCTTTCTATGGACTTCATGGTTAATGAC
AGTCCTCTTGCAGGTAAAGAAGGTAAATTCGTTACTTCAAGACATTTAAGAGACAGACTTTTCAAGGAACTTAATACAGA
TGTTAGTTTAAGAGTTGAGGAAACACCTGGCGTTGAGAACTCATTTAAGGTTTCAGGACGTGGTGAGCTTCATCTTTCAG
TTCTTATTGAGAATATGAGAAGAGAAGGTTATGAATTTGCAGTAAGTAAAGCCGAGGTACTCTACCACACAGATGAGAGA
GGTAAGAAGCTTGAGCCTATGGAACTTGCTTATATCGATGTCCCAGATGACTGCACAGGATCTGTTATCCAGAAGTTAAG
CCAGAGAAAAGGCGAACTCCTTGGTATGTCACCAATTAACGGCGGATACACAAGACTTCAATTCTCTATTCCTTCAAGAG
GTCTTATCGGATACAGAGGCGAATTCCTTACTGATACTAAGGGTAACGGTATTATCAATTCTTCTTTTGAAGGATATGAA
GAATACAAAGGAGACATTTCTTACAGAAAGAATGGTTCTCTTATCGCTTACGAAAGCGGTGATGCTATCACTTATGGTCT
TTTCAATGCGCAGGAAAGAGGTACTCTTTTCATTGGACCAGGTGAGAAAGTATATGCCGGAATGATCGTTGGCGAGAATC
CTCGTACTGAGGATATTGAGGTTAATGTATGCAAGACAAAGCATCTTACCAACACTCGTTCTTCAAGTGCTGATGAGGCC
CTCCGTCTTGTTCCGCCTAAGATTCTTAGCTTGGAGCAGGCACTGGATTATATTGACACAGACGAATTACTTGAAGTAAC
ACCTAAGAGTCTTAGAATCCGTAAGAAGATTCTTGATCACACAGCTCGTTACAGAGCAAACAAAAAGTAA

Upstream 100 bases:

>100_bases
TTTATATATTTAGTATTGTTTTTTAAGAATATTGTGATAGAATATAAAAGTTGCTAATCATAGAAGATATTTTGAGTTTA
ATTCAGGAAGGACATTATTA

Downstream 100 bases:

>100_bases
TTATTTTTAGGAGGTTTGAATTATGGATAGCGATTTAGGAGCTAAAGTTAAGAAGTTAAGAATTGCACACGGTCTTACAC
AGGAAGACGTTGCTAAAGCA

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MKTKRDDIRNIAIIAHVDHGKTTLVDELLKQSGTFRANQEVAERVMDSNDIERERGITILSKNTAITYKDTKINIIDTPG
HADFGGEVERVLKMVNGVILVVDAFEGVMPQTKFVLQKALDMNLSVIVCINKIDRPEARPEEVIDEILELFIDLDANEDQ
LDCPFIFASAKSGYAMADLNDEKKDMQPLFDCIVNNIPAPEGDPDADTQMLISTIDYNEFVGRIGVGKIDNGSLKVNQEV
MIVNHHDPSVKKRVRITKLYTFNGLNKVEVNEAGIGEIVAVSGIADIHIGDTICSLNNPVAIPFQKISEPTLSMDFMVND
SPLAGKEGKFVTSRHLRDRLFKELNTDVSLRVEETPGVENSFKVSGRGELHLSVLIENMRREGYEFAVSKAEVLYHTDER
GKKLEPMELAYIDVPDDCTGSVIQKLSQRKGELLGMSPINGGYTRLQFSIPSRGLIGYRGEFLTDTKGNGIINSSFEGYE
EYKGDISYRKNGSLIAYESGDAITYGLFNAQERGTLFIGPGEKVYAGMIVGENPRTEDIEVNVCKTKHLTNTRSSSADEA
LRLVPPKILSLEQALDYIDTDELLEVTPKSLRIRKKILDHTARYRANKK

Sequences:

>Translated_609_residues
MKTKRDDIRNIAIIAHVDHGKTTLVDELLKQSGTFRANQEVAERVMDSNDIERERGITILSKNTAITYKDTKINIIDTPG
HADFGGEVERVLKMVNGVILVVDAFEGVMPQTKFVLQKALDMNLSVIVCINKIDRPEARPEEVIDEILELFIDLDANEDQ
LDCPFIFASAKSGYAMADLNDEKKDMQPLFDCIVNNIPAPEGDPDADTQMLISTIDYNEFVGRIGVGKIDNGSLKVNQEV
MIVNHHDPSVKKRVRITKLYTFNGLNKVEVNEAGIGEIVAVSGIADIHIGDTICSLNNPVAIPFQKISEPTLSMDFMVND
SPLAGKEGKFVTSRHLRDRLFKELNTDVSLRVEETPGVENSFKVSGRGELHLSVLIENMRREGYEFAVSKAEVLYHTDER
GKKLEPMELAYIDVPDDCTGSVIQKLSQRKGELLGMSPINGGYTRLQFSIPSRGLIGYRGEFLTDTKGNGIINSSFEGYE
EYKGDISYRKNGSLIAYESGDAITYGLFNAQERGTLFIGPGEKVYAGMIVGENPRTEDIEVNVCKTKHLTNTRSSSADEA
LRLVPPKILSLEQALDYIDTDELLEVTPKSLRIRKKILDHTARYRANKK
>Mature_609_residues
MKTKRDDIRNIAIIAHVDHGKTTLVDELLKQSGTFRANQEVAERVMDSNDIERERGITILSKNTAITYKDTKINIIDTPG
HADFGGEVERVLKMVNGVILVVDAFEGVMPQTKFVLQKALDMNLSVIVCINKIDRPEARPEEVIDEILELFIDLDANEDQ
LDCPFIFASAKSGYAMADLNDEKKDMQPLFDCIVNNIPAPEGDPDADTQMLISTIDYNEFVGRIGVGKIDNGSLKVNQEV
MIVNHHDPSVKKRVRITKLYTFNGLNKVEVNEAGIGEIVAVSGIADIHIGDTICSLNNPVAIPFQKISEPTLSMDFMVND
SPLAGKEGKFVTSRHLRDRLFKELNTDVSLRVEETPGVENSFKVSGRGELHLSVLIENMRREGYEFAVSKAEVLYHTDER
GKKLEPMELAYIDVPDDCTGSVIQKLSQRKGELLGMSPINGGYTRLQFSIPSRGLIGYRGEFLTDTKGNGIINSSFEGYE
EYKGDISYRKNGSLIAYESGDAITYGLFNAQERGTLFIGPGEKVYAGMIVGENPRTEDIEVNVCKTKHLTNTRSSSADEA
LRLVPPKILSLEQALDYIDTDELLEVTPKSLRIRKKILDHTARYRANKK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=492, Percent_Identity=28.8617886178862, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=45.8646616541353, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=43.5374149659864, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4503483, Length=148, Percent_Identity=37.8378378378378, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI25306283, Length=144, Percent_Identity=40.9722222222222, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19923640, Length=144, Percent_Identity=40.9722222222222, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI25306287, Length=144, Percent_Identity=40.9722222222222, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI217272892, Length=139, Percent_Identity=41.0071942446043, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI217272894, Length=139, Percent_Identity=41.0071942446043, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI34147630, Length=275, Percent_Identity=29.0909090909091, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI53729339, Length=138, Percent_Identity=37.6811594202899, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI53729337, Length=138, Percent_Identity=37.6811594202899, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=34.8837209302326, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI48994988, Length=602, Percent_Identity=53.4883720930233, Blast_Score=642, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=509, Percent_Identity=29.8624754420432, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=40.5405405405405, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=31.7241379310345, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789559, Length=171, Percent_Identity=34.5029239766082, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789737, Length=239, Percent_Identity=29.2887029288703, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790412, Length=239, Percent_Identity=29.2887029288703, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17557151, Length=284, Percent_Identity=34.8591549295775, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=42.2535211267606, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17533571, Length=143, Percent_Identity=43.3566433566434, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=39.5522388059701, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=37.6923076923077, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=37.6923076923077, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17506493, Length=178, Percent_Identity=32.5842696629214, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=267, Percent_Identity=28.4644194756554, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994658, Length=141, Percent_Identity=35.4609929078014, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323320, Length=517, Percent_Identity=28.2398452611219, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324707, Length=150, Percent_Identity=42, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=150, Percent_Identity=42, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323098, Length=151, Percent_Identity=41.0596026490066, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=36.4864864864865, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324761, Length=255, Percent_Identity=29.0196078431373, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=35, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324550, Length=200, Percent_Identity=28.5, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706572, Length=490, Percent_Identity=26.530612244898, Blast_Score=148, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24582462, Length=145, Percent_Identity=44.8275862068966, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=41.044776119403, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28574573, Length=144, Percent_Identity=38.8888888888889, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24585711, Length=152, Percent_Identity=37.5, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585713, Length=152, Percent_Identity=37.5, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585709, Length=152, Percent_Identity=37.5, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221458488, Length=142, Percent_Identity=43.6619718309859, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281363316, Length=249, Percent_Identity=29.3172690763052, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864358, Length=249, Percent_Identity=29.3172690763052, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28572034, Length=146, Percent_Identity=34.2465753424658, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19921738, Length=243, Percent_Identity=28.8065843621399, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67854; Mature: 67854

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKRDDIRNIAIIAHVDHGKTTLVDELLKQSGTFRANQEVAERVMDSNDIERERGITIL
CCCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHCCEEEE
SKNTAITYKDTKINIIDTPGHADFGGEVERVLKMVNGVILVVDAFEGVMPQTKFVLQKAL
ECCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
DMNLSVIVCINKIDRPEARPEEVIDEILELFIDLDANEDQLDCPFIFASAKSGYAMADLN
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCEEEECCC
DEKKDMQPLFDCIVNNIPAPEGDPDADTQMLISTIDYNEFVGRIGVGKIDNGSLKVNQEV
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCHHHHHCCCCCCEECCCCEEECCEE
MIVNHHDPSVKKRVRITKLYTFNGLNKVEVNEAGIGEIVAVSGIADIHIGDTICSLNNPV
EEEECCCCCHHHEEEEEEEEEECCCCEEEECCCCCCCEEEECCEEEEEECCEEECCCCCE
AIPFQKISEPTLSMDFMVNDSPLAGKEGKFVTSRHLRDRLFKELNTDVSLRVEETPGVEN
ECCHHHCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCC
SFKVSGRGELHLSVLIENMRREGYEFAVSKAEVLYHTDERGKKLEPMELAYIDVPDDCTG
CEEECCCCCEEHHHHHHHHHHCCCEEEEECEEEEEEECCCCCCCCCEEEEEEECCCCCHH
SVIQKLSQRKGELLGMSPINGGYTRLQFSIPSRGLIGYRGEFLTDTKGNGIINSSFEGYE
HHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCEECCCCCCHH
EYKGDISYRKNGSLIAYESGDAITYGLFNAQERGTLFIGPGEKVYAGMIVGENPRTEDIE
HHCCCCEEECCCCEEEEECCCEEEEEEECCCCCCEEEECCCCEEEEEEEECCCCCCCCEE
VNVCKTKHLTNTRSSSADEALRLVPPKILSLEQALDYIDTDELLEVTPKSLRIRKKILDH
EEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHH
TARYRANKK
HHHHCCCCC
>Mature Secondary Structure
MKTKRDDIRNIAIIAHVDHGKTTLVDELLKQSGTFRANQEVAERVMDSNDIERERGITIL
CCCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHCCEEEE
SKNTAITYKDTKINIIDTPGHADFGGEVERVLKMVNGVILVVDAFEGVMPQTKFVLQKAL
ECCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
DMNLSVIVCINKIDRPEARPEEVIDEILELFIDLDANEDQLDCPFIFASAKSGYAMADLN
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCEEEECCC
DEKKDMQPLFDCIVNNIPAPEGDPDADTQMLISTIDYNEFVGRIGVGKIDNGSLKVNQEV
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCHHHHHCCCCCCEECCCCEEECCEE
MIVNHHDPSVKKRVRITKLYTFNGLNKVEVNEAGIGEIVAVSGIADIHIGDTICSLNNPV
EEEECCCCCHHHEEEEEEEEEECCCCEEEECCCCCCCEEEECCEEEEEECCEEECCCCCE
AIPFQKISEPTLSMDFMVNDSPLAGKEGKFVTSRHLRDRLFKELNTDVSLRVEETPGVEN
ECCHHHCCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCC
SFKVSGRGELHLSVLIENMRREGYEFAVSKAEVLYHTDERGKKLEPMELAYIDVPDDCTG
CEEECCCCCEEHHHHHHHHHHCCCEEEEECEEEEEEECCCCCCCCCEEEEEEECCCCCHH
SVIQKLSQRKGELLGMSPINGGYTRLQFSIPSRGLIGYRGEFLTDTKGNGIINSSFEGYE
HHHHHHHHCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCEECCCCCCHH
EYKGDISYRKNGSLIAYESGDAITYGLFNAQERGTLFIGPGEKVYAGMIVGENPRTEDIE
HHCCCCEEECCCCEEEEECCCEEEEEEECCCCCCEEEECCCCEEEEEEEECCCCCCCCEE
VNVCKTKHLTNTRSSSADEALRLVPPKILSLEQALDYIDTDELLEVTPKSLRIRKKILDH
EEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHH
TARYRANKK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]